Page last updated: 2024-08-21

toluene 2,4-diisocyanate and Dermatitis, Allergic Contact

toluene 2,4-diisocyanate has been researched along with Dermatitis, Allergic Contact in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.35)18.2507
2000's14 (60.87)29.6817
2010's6 (26.09)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Aerts, O; Dendooven, E; Foubert, K; Lambert, J; Naessens, T; Pieters, L1
Aihara, R; Fukuyama, T; Iwashita, N; Kushiro, M; Miyake, S; Miyasaka, A; Morimoto, A; Ookawara, T; Takagi, Y1
Fukuyama, T; Ishimota, M; Makino, E; Tajiki-Nishino, R; Tajima, H; Watanabe, Y1
Bäumer, W; Ehling, S; Fukuyama, T; Ko, MC; Olivry, T1
Bungo, T; Higaki, T; Inawaka, K; Kawamura, S; Morimoto, T; Ota, M1
Anderson, SE; Kashon, ML; Long, CM; Lukomska, E; Marshall, NB; Meade, BJ; Shane, H1
Bäumer, W; Crapo, JD; Daniele, MA; Fukuyama, T; Oberley, R; Stover, K; Young, AT1
Cho, JH; Jeong, SH; Kang, HG; Kim, HR; Ku, HO; Lee, KJ; Pyo, HM; Ryu, DY; Son, SW1
Fukuyama, T; Harada, T; Hayashi, K; Kosaka, T; Saito, TR; Shuto, Y; Tajima, Y; Ueda, H1
Lammintausta, K; Liippo, J1
Bäumer, W; Kietzmann, M; Kleuser, B; Lüth, A; Mischke, R; Reines, I; Tschernig, T1
Cho, JH; Jeong, SH; Kang, HG; Ku, HO; Pyo, HM; Ryu, DY; Son, SW; Yun, SM1
Aalto-Korte, K; Henriks-Eckerman, ML; Jolanki, R; Kuuliala, O; Suuronen, K1
Mahendran, R; Stables, GI; Wilkinson, SM1
Danno, K; Fuchibe, K; Fujii, M; Koda, A; Kohno, S; Mizutani, N; Nabe, T1
Cunningham, AR; Hoet, PH; Mandervelt, C; Nemery, B; Vanhooren, HM; Vanoirbeek, JA; Xu, H1
Ceuppens, JL; Hoet, PH; Nemery, B; Tarkowski, M; Vanoirbeek, JA; Verbeken, EK1
Arredouani, MS; Fedulov, A; Hubeau, C; Kobzik, L; Lim, RH1
Belsito, DV; Thompson, T1
Ehinger, AM; Ehinger, B; Gorr, G; Hoppmann, J; Kietzmann, M; Telser, E1
Meade, BJ; Munson, AE; Woolhiser, MR1
Estlander, T; Jolanki, R; Kanerva, L; Keskinen, H1
Bäumer, W; Ehinger, AM; Ehinger, B; Gorr, G; Hoppmann, J; Kietzmann, M1

Other Studies

23 other study(ies) available for toluene 2,4-diisocyanate and Dermatitis, Allergic Contact

ArticleYear
Isocyanates may contribute to allergic contact dermatitis from diabetes devices and wound dressings.
    Contact dermatitis, 2022, Volume: 87, Issue:5

    Topics: Allergens; Amines; Bandages; Dermatitis, Allergic Contact; Diabetes Mellitus; Humans; Isocyanates; Polyurethanes; Toluene 2,4-Diisocyanate

2022
Acute and subacute oral administration of mycotoxin deoxynivalenol exacerbates the pro-inflammatory and pro-pruritic responses in a mouse model of allergic dermatitis.
    Archives of toxicology, 2020, Volume: 94, Issue:12

    Topics: Administration, Oral; Animals; Cytokines; Dendritic Cells; Dermatitis, Allergic Contact; Disease Models, Animal; Female; Humans; Inflammation Mediators; Keratinocytes; Mice, Inbred BALB C; Pruritus; Skin; Th2 Cells; THP-1 Cells; Toluene 2,4-Diisocyanate; Trichothecenes

2020
Oral Administration of Bisphenol A Directly Exacerbates Allergic Airway Inflammation but Not Allergic Skin Inflammation in Mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 10-01, Volume: 165, Issue:2

    Topics: Administration, Oral; Animals; Benzhydryl Compounds; Cell Line; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Disease Progression; Environmental Pollutants; Epithelial Cells; Female; Humans; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Phenols; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate

2018
Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons.
    Acta dermato-venereologica, 2019, May-01, Volume: 99, Issue:6

    Topics: Animals; Calcium; Cell Degranulation; Cells, Cultured; Dermatitis, Allergic Contact; Female; Ganglia, Spinal; Gene Expression; Indoles; Injections, Intradermal; Macaca mulatta; Male; Mast Cells; Mice; Neurokinin B; Pruritus; Pyridines; Receptors, Bombesin; RNA, Messenger; Sensory Receptor Cells; Single-Cell Analysis; Toluene 2,4-Diisocyanate

2019
Effect of simultaneous exposure to mixture of two skin sensitizers on skin sensitization response in guinea pigs and mice.
    The Journal of toxicological sciences, 2014, Volume: 39, Issue:1

    Topics: Animals; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Mice; Mice, Inbred CBA; Oxazolone; Phthalic Anhydrides; Skin; Skin Tests; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate

2014
A Role for Regulatory T Cells in a Murine Model of Epicutaneous Toluene Diisocyanate Sensitization.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 152, Issue:1

    Topics: Animals; Antigens, CD; Cell Proliferation; Cells, Cultured; CTLA-4 Antigen; Dermatitis, Allergic Contact; Disease Models, Animal; Female; Inducible T-Cell Co-Stimulator Protein; Integrin alpha Chains; Kinetics; Lymphocyte Activation; Mice, Inbred BALB C; Neuropilin-1; Phenotype; Receptors, CCR6; Skin; T-Lymphocytes, Regulatory; Toluene 2,4-Diisocyanate

2016
Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis.
    Archives of dermatological research, 2016, Volume: 308, Issue:10

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Cell Line; Dendritic Cells; Dermatitis, Allergic Contact; Disease Models, Animal; Ear; Female; Humans; Infant, Newborn; Inflammation; Interleukin-1beta; Interleukin-4; Keratinocytes; Metalloporphyrins; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Pruritus; Skin; Skin Cream; Superoxide Dismutase; Toluene 2,4-Diisocyanate

2016
Intracellular expression of cytokines and granzyme B in auricular lymph nodes draining skin exposed to irritants and sensitizers.
    Toxicology, 2008, Sep-04, Volume: 250, Issue:2-3

    Topics: Animals; Cytokines; Dermatitis, Allergic Contact; Dermatitis, Contact; Diagnosis, Differential; Dinitrochlorobenzene; Ear Auricle; Female; Granzymes; Immunoassay; Irritants; Local Lymph Node Assay; Lymph Nodes; Mice; Mice, Inbred CBA; Oxytocin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Skin Physiological Phenomena; Toluene 2,4-Diisocyanate

2008
Use of long term dermal sensitization followed by intratracheal challenge method to identify low-dose chemical-induced respiratory allergic responses in mice.
    Toxicology letters, 2008, Oct-01, Volume: 181, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Dose-Response Relationship, Immunologic; Environmental Pollutants; Female; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Phthalic Anhydrides; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Trachea

2008
Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients.
    Contact dermatitis, 2008, Volume: 59, Issue:2

    Topics: Allergens; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Finland; Humans; Isocyanates; Male; Patch Tests; Risk Factors; Toluene 2,4-Diisocyanate

2008
Topical application of sphingosine-1-phosphate and FTY720 attenuate allergic contact dermatitis reaction through inhibition of dendritic cell migration.
    The Journal of investigative dermatology, 2009, Volume: 129, Issue:8

    Topics: Administration, Topical; Animals; Cell Movement; Dendritic Cells; Dermatitis, Allergic Contact; Female; Fingolimod Hydrochloride; Histocompatibility Antigens Class II; Immunosuppressive Agents; Lysophospholipids; Mice; Mice, Inbred BALB C; Oxadiazoles; Propylene Glycols; Receptors, Lysosphingolipid; Skin; Sphingosine; Thiophenes; Toluene 2,4-Diisocyanate

2009
Gene expression profiles and pathways in skin inflammation induced by three different sensitizers and an irritant.
    Toxicology letters, 2009, Oct-28, Volume: 190, Issue:2

    Topics: Allergens; Animals; Cytokines; Dermatitis, Allergic Contact; Dermatitis, Contact; Dinitrochlorobenzene; DNA Primers; Ear, External; Female; Gene Expression Profiling; Irritants; Mice; Mice, Inbred CBA; Oligonucleotide Array Sequence Analysis; Oxazolone; Receptors, Cytokine; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin; Toluene 2,4-Diisocyanate

2009
Occupational contact allergy to monomeric isocyanates.
    Contact dermatitis, 2012, Volume: 67, Issue:2

    Topics: Allergens; Aniline Compounds; Cyanates; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Humans; Isocyanates; Male; Occupations; Toluene 2,4-Diisocyanate

2012
Contact leukoderma secondary to occupational toluenediamine sulfate exposure.
    Contact dermatitis, 2002, Volume: 47, Issue:2

    Topics: Adult; Allergens; Chemical Industry; Dermatitis, Allergic Contact; Dermatitis, Occupational; Follow-Up Studies; Hair Dyes; Hand Dermatoses; Humans; Hypopigmentation; Male; Occupational Exposure; Patch Tests; Risk Assessment; Toluene 2,4-Diisocyanate

2002
Delayed type allergic itch-associated response induced by toluene-2,4-diisocyanate in hairless mice.
    Journal of pharmacological sciences, 2003, Volume: 93, Issue:1

    Topics: Animals; Dermatitis, Allergic Contact; Male; Mice; Mice, Hairless; Mice, Inbred ICR; Pruritus; Time Factors; Toluene 2,4-Diisocyanate

2003
Validity of methods to predict the respiratory sensitizing potential of chemicals: A study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 76, Issue:2

    Topics: Adjuvants, Immunologic; Administration, Cutaneous; Allergens; Animals; Asthma; Bronchoalveolar Lavage; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Immunoglobulin E; Local Lymph Node Assay; Lung; Lymph Nodes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Occupational Exposure; Oxazolone; Piperidines; Predictive Value of Tests; Structure-Activity Relationship; Toluene 2,4-Diisocyanate; Triazines

2003
Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 80, Issue:2

    Topics: Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dermatitis, Allergic Contact; Disease Models, Animal; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Occupational Exposure; Plethysmography, Whole Body; Respiratory Mechanics; Toluene 2,4-Diisocyanate

2004
Maternal allergic contact dermatitis causes increased asthma risk in offspring.
    Respiratory research, 2007, Jul-27, Volume: 8

    Topics: Animals; Asthma; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Disease Susceptibility; Female; Gene Expression Regulation; Interleukin-4; Irritants; Lung; Male; Maternal Exposure; Mice; Mice, Inbred BALB C; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate

2007
Allergic contact dermatitis from a diisocyanate in wool processing.
    Contact dermatitis, 1997, Volume: 37, Issue:5

    Topics: Animals; Dermatitis, Allergic Contact; Female; Humans; Middle Aged; Occupational Exposure; Patch Tests; Toluene 2,4-Diisocyanate; Wool

1997
Effects of the phosphodiesterase 4 inhibitor RPR 73401 in a model of immunological inflammation.
    European journal of pharmacology, 2000, Mar-24, Volume: 392, Issue:1-2

    Topics: Administration, Topical; Animals; Benzamides; Cyclosporine; Dermatitis, Allergic Contact; Dinitrobenzenes; Disease Models, Animal; Female; Interleukin-4; Mice; Mice, Inbred BALB C; Phosphodiesterase Inhibitors; Pyridines; Toluene 2,4-Diisocyanate

2000
Comparison of mouse strains using the local lymph node assay.
    Toxicology, 2000, May-05, Volume: 146, Issue:2-3

    Topics: Acrolein; Animals; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Female; Lymph Nodes; Mice; Mice, Inbred Strains; Species Specificity; Stimulation, Chemical; Thymidine; Toluene 2,4-Diisocyanate

2000
Asthma from diisocyanates is not mediated through a Type IV, patch-test-positive mechanism.
    Contact dermatitis, 2001, Volume: 44, Issue:4

    Topics: Adult; Allergens; Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hand Dermatoses; Humans; Isocyanates; Male; Middle Aged; Paint; Patch Tests; Toluene 2,4-Diisocyanate

2001
Effects of the phosphodiesterase 4 inhibitors SB 207499 and AWD 12-281 on the inflammatory reaction in a model of allergic dermatitis.
    European journal of pharmacology, 2002, Jun-20, Volume: 446, Issue:1-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amides; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Dermatitis, Allergic Contact; Ear; Edema; Immunoglobulin E; Indoles; Interleukin-1; Interleukin-4; Mice; Mice, Inbred BALB C; Nitriles; Phosphodiesterase Inhibitors; Skin; Time Factors; Toluene 2,4-Diisocyanate

2002