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toluene 2,4-diisocyanate and Bronchial Hyperreactivity

toluene 2,4-diisocyanate has been researched along with Bronchial Hyperreactivity in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (48.48)	18.2507
2000's	13 (39.39)	29.6817
2010's	4 (12.12)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alpizar, YA; Boonen, B; Devos, FC; Hoet, PH; Hox, V; Liston, A; Maes, T; Nemery, B; Pollaris, L; Seys, S; Talavera, K; Vanoirbeek, JA	1
De Vooght, V; Haenen, S; Hoet, PH; Nemery, B; Vanoirbeek, JA; Verbeken, E	1
Boland, S; De Vooght, V; Dinsdale, D; Hoet, PH; Hussain, S; Luyts, K; Marano, F; Martens, JA; Nemery, B; Thomassen, LC; Vanoirbeek, JA; Verbeken, E	1
Moscato, G; Pala, G; Pignatti, P	1
Pałczyński, C; Swierczyńska-Machura, D	1
Cuesta, J; De Las Heras, M; Fernández-Nieto, M; Novalbos, A; Quirce, S; Sastre, J	1
Jin, SM; Kim, SS; Lee, KS; Lee, YC	1
Johnson, VJ; Luster, MI; Matheson, JM	1
Johnson, VJ; Luster, MI; Matheson, JM; Vallyathan, V	1
Ariizumi, M; Kouadio, K; Todoriki, H; Tuekpe, MK; Zheng, KC	1
Fujimura, M; Furusho, S; Kasahara, K; Kita, T; Myou, S; Nakao, S; Sato, S; Takehara, K; Yasui, M	1
Alenius, H; Laitinen, A; Luukkonen, R; Majuri, ML; Mäntylä, T; Meuronen, A; Nordman, H; Piirilä, PL; Wolff, HJ	1
Baur, X; Marczynski, B; Marek, W; Potthast, J; Raulf, M; Tennie, L	1
Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Pivirotto, F; Saetta, M; Turato, G	1
Campbell, TP; Fabbri, L; Karol, MH; Maestrelli, P; Mapp, CE; Saetta, M; Tollerud, DJ	1
Bacci, E; Bancalari, L; Carrara, M; Dente, FL; Di Franco, A; Giannini, D; Giuntini, C; Paggiaro, PL; Vagaggini, B	1
Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A	1
Marek, W; Philippou, S; Potthast, J	1
Baur, X; Marczynski, B; Marek, W; Potthast, J	2
Boscaro, M; De Marzo, N; Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M	1
Biscaldi, G; Corsico, A; Dellabianca, A; Gherson, G; Moscato, G; Vinci, G	1
Ban, M; Bonnet, P; Gagnaire, F; Lemonnier, M; Micillino, JC	1
Ban, M; Bonnet, P; Cour, C; Gagnaire, F; Hettich, D; Micillino, JC	1
Nahm, DH; Park, HS	1
Fedan, JS; Frazer, DG; Huang, J; Millecchia, LL	1
Frossard, N; Kopferschmitt-Kubler, MC; Pauli, G; Rohde, G	1
Buckley, TL; Dormans, J; Garssen, J; Muis, TL; Nijkamp, FP; Scheerens, H; Van Loveren, H	1
Choi, IS; Jang, AS; Koh, YI; Lee, KJ; Moon, JD	1
Karol, MH; Lange, RW; Lemus, R; Luster, MI; Matheson, JM	1
Kwak, YG; Lee, YC; Song, CH	1
Kim, HY; Kim, SS; Lee, SK; Nahm, DH; Park, HS	1
Boschetto, P; De Marzo, N; Fryer, AA; Hemmingsen, A; Mapp, CE; Padoan, M; Pozzato, V; Spiteri, MA; Strange, RC	1

Reviews

1 review(s) available for toluene 2,4-diisocyanate and Bronchial Hyperreactivity

Article	Year
[Pathogenetic and clinical aspects of diisocyanate asthma]. Medycyna pracy, 2012, Volume: 63, Issue:1 Topics: Air Pollutants, Occupational; Animals; Asthma; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Humans; Immunoglobulin E; Mice; Occupational Diseases; Occupational Exposure; T-Lymphocytes; Toluene 2,4-Diisocyanate	2012

Trials

1 trial(s) available for toluene 2,4-diisocyanate and Bronchial Hyperreactivity

Article	Year
Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate. The American review of respiratory disease, 1993, Volume: 148, Issue:2 Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Placebos; Toluene 2,4-Diisocyanate	1993

Article

Year

Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate.

The American review of respiratory disease, 1993, Volume: 148, Issue:2

Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Placebos; Toluene 2,4-Diisocyanate

1993

Other Studies

31 other study(ies) available for toluene 2,4-diisocyanate and Bronchial Hyperreactivity

Article	Year
Neuro-immune interactions in chemical-induced airway hyperreactivity. The European respiratory journal, 2016, Volume: 48, Issue:2 Topics: Animals; Asthma; Bronchial Hyperreactivity; Calcium; CHO Cells; Cricetulus; Inflammation; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Sensory Receptor Cells; Toluene 2,4-Diisocyanate; TRPA1 Cation Channel; TRPV Cation Channels	2016
Oropharyngeal aspiration: an alternative route for challenging in a mouse model of chemical-induced asthma. Toxicology, 2009, May-02, Volume: 259, Issue:1-2 Topics: Administration, Intranasal; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Disease Models, Animal; Eosinophils; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Respiratory Aspiration; Toluene 2,4-Diisocyanate; Up-Regulation	2009
Lung exposure to nanoparticles modulates an asthmatic response in a mouse model. The European respiratory journal, 2011, Volume: 37, Issue:2 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Gold; Immunoglobulin E; Lung; Macrophages; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neutrophils; Pulmonary Edema; Titanium; Toluene 2,4-Diisocyanate	2011
Occupational exposure to toluene diisocyanate and neutrophilic bronchitis without asthma. Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:6 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchitis; Chronic Disease; Cough; Female; Humans; Lymphocyte Count; Neutrophils; Occupational Diseases; Occupational Exposure; Spirometry; Sputum; Toluene 2,4-Diisocyanate	2011
Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge. Chest, 2003, Volume: 123, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyanates; False Negative Reactions; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Middle Aged; Monitoring, Physiologic; Occupational Diseases; Prospective Studies; Toluene 2,4-Diisocyanate	2003
Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma. The Journal of allergy and clinical immunology, 2004, Volume: 113, Issue:5 Topics: Animals; Anti-Bacterial Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Doxycycline; Female; Inflammation; Lung; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Ovalbumin; Protease Inhibitors; RNA, Messenger; Toluene 2,4-Diisocyanate	2004
Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate. Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1 Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Enzyme-Linked Immunosorbent Assay; Eosinophils; Immunoglobulin E; Mice; Mice, Inbred C57BL; Mice, Knockout; Occupational Diseases; Peroxidases; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Th2 Cells; Toluene 2,4-Diisocyanate	2005
Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma. Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1 Topics: Adoptive Transfer; Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dermatitis, Contact; Eosinophils; Gene Expression; Immunoglobulin E; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peroxidase; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Toluene 2,4-Diisocyanate	2005
Airway inflammatory and immunological events in a rat model exposed to toluene diisocyanate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2005, Volume: 43, Issue:8 Topics: Administration, Inhalation; Allergens; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Female; Inhalation Exposure; Rats; Rats, Wistar; Toluene 2,4-Diisocyanate	2005
Role of intercellular adhesion molecule-1 in a murine model of toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:10 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokine CXCL2; Chemokines; Immunoglobulin E; Immunoglobulin G; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-4; Interleukin-5; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2006
Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure. Allergy, 2008, Volume: 63, Issue:5 Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoscopy; Female; Humans; Inflammation; Interleukin-4; Macrophages; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Respiratory Mucosa; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha	2008
Cellular and mediator profile in bronchoalveolar lavage of guinea pigs after toluene diisocyanate (TDI) exposure. Lung, 1995, Volume: 173, Issue:1 Topics: Animals; Arachidonic Acid; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Calcimycin; Dose-Response Relationship, Drug; Eosinophils; Female; Guinea Pigs; Inflammation Mediators; Leukocyte Count; Leukotrienes; Prostaglandin D2; Thromboxane B2; Toluene 2,4-Diisocyanate	1995
Airway wall remodeling after cessation of exposure to isocyanates in sensitized asthmatic subjects. American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:2 Pt 1 Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate	1995
Predictive value of airways hyperresponsiveness and circulating IgE for identifying types of responses to toluene diisocyanate inhalation challenge. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:3 Pt 1 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi-Square Distribution; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Occupational Diseases; Predictive Value of Tests; Reproducibility of Results; Skin Tests; Toluene 2,4-Diisocyanate	1994
Bronchial hyperresponsiveness and toluene diisocyanate. Long-term change in sensitized asthmatic subjects. Chest, 1993, Volume: 103, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate	1993
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1994, Volume: 24, Issue:1 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate	1994
Ultrastructural study of rabbit lung tissue subsequent to capsaicin treatment over several days. Respiration; international review of thoracic diseases, 1993, Volume: 60, Issue:4 Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Capsaicin; Injections, Subcutaneous; Lung; Nerve Fibers; Neurosecretory Systems; Rabbits; Toluene 2,4-Diisocyanate	1993
[Toluene diisocyanate-induced bronchial hyperreactivity in an animal model of occupationally-induced lung diseases]. Pneumologie (Stuttgart, Germany), 1993, Volume: 47, Issue:3 Topics: Animals; Bronchial Hyperreactivity; Lung Volume Measurements; Maximum Allowable Concentration; Occupational Diseases; Rabbits; Toluene 2,4-Diisocyanate	1993
Bronchial responsiveness to ultrasonic fog in occupational asthma due to toluene diisocyanate. Chest, 1993, Volume: 104, Issue:4 Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Chloride; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Ultrasonics; Water	1993
Toluene diisocyanate induction of airway hyperresponsiveness at the threshold limit value (10 ppb) in rabbits. Lung, 1995, Volume: 173, Issue:6 Topics: Acetylcholine; Airway Resistance; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchial Provocation Tests; Disease Models, Animal; Elasticity; Lung Diseases; Maximum Allowable Concentration; Occupational Diseases; Rabbits; Reproducibility of Results; Toluene 2,4-Diisocyanate	1995
Bronchial responsiveness and inflammation in guinea-pigs exposed to toluene diisocyanate: a study on single and repeated exposure. Toxicology, 1996, Dec-02, Volume: 114, Issue:2 Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Female; Guinea Pigs; Inflammation; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate	1996
Role of tachykinins and neutral endopeptidase in toluene diisocyanate-induced bronchial hyperresponsiveness in guinea pigs. Toxicology, 1997, Jan-15, Volume: 116, Issue:1-3 Topics: Animals; Bronchial Hyperreactivity; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Neprilysin; Tachykinins; Toluene 2,4-Diisocyanate	1997
Prognostic factors for toluene diisocyanate-induced occupational asthma after removal from exposure. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27, Issue:10 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Environmental Exposure; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Longitudinal Studies; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Prognosis; Smoking; Steroids; Toluene 2,4-Diisocyanate	1997
Airway hyperreactivity elicited by toluene diisocyanate (TDI)-albumin conjugate is not accompanied by airway eosinophilic infiltration in guinea pigs. Archives of toxicology, 1998, Volume: 72, Issue:3 Topics: Albumins; Allergens; Animals; Bronchi; Bronchial Hyperreactivity; Eosinophils; Guinea Pigs; Male; Toluene 2,4-Diisocyanate; Trachea	1998
Increase in non-specific bronchial hyperresponsiveness without specific response to isocyanate in isocyanate-induced asthma: a pilot study. Respiratory medicine, 1998, Volume: 92, Issue:9 Topics: Adult; Air Pollutants, Occupational; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Female; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Parasympathomimetics; Pilot Projects; Predictive Value of Tests; Statistics, Nonparametric; Toluene 2,4-Diisocyanate	1998
Long-term topical exposure to toluene diisocyanate in mice leads to antibody production and in vivo airway hyperresponsiveness three hours after intranasal challenge. American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:4 Pt 1 Topics: Administration, Intranasal; Administration, Topical; Airway Resistance; Animals; Antibody Formation; Bronchial Hyperreactivity; Immunization; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Lung; Male; Mice; Mice, Inbred BALB C; Respiratory Hypersensitivity; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate; Trachea	1999
Increase in airway hyperresponsiveness among workers exposed to methylene diphenyldiisocyanate compared to workers exposed to toluene diisocyanate at a petrochemical plant in Korea. American journal of industrial medicine, 2000, Volume: 37, Issue:6 Topics: Adult; Air Pollutants, Occupational; Allergens; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chemical Industry; Female; Forced Expiratory Volume; Humans; Intradermal Tests; Isocyanates; Korea; Male; Occupational Diseases; Petroleum; Toluene 2,4-Diisocyanate	2000
Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI). Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:7 Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Disease Models, Animal; Female; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Nude; Toluene 2,4-Diisocyanate	2001
Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. Journal of immunology (Baltimore, Md. : 1950), 2002, Apr-01, Volume: 168, Issue:7 Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Migration Inhibition; Cell Movement; Disease Models, Animal; Endothelial Growth Factors; Extravasation of Diagnostic and Therapeutic Materials; Female; Indoles; Inflammation; Leukocyte Count; Lymphokines; Mice; Mice, Inbred BALB C; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Toluene 2,4-Diisocyanate; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Specific immunoglobulin E and immunoglobulin G antibodies to toluene diisocyanate-human serum albumin conjugate: useful markers for predicting long-term prognosis in toluene diisocyanate-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:4 Topics: Asthma; Biomarkers; Bronchial Hyperreactivity; Humans; Immunoglobulin E; Immunoglobulin G; Kinetics; Prognosis; Serum Albumin; Toluene 2,4-Diisocyanate	2002
Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates. The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:5 Topics: Adult; Asthma; Bronchial Hyperreactivity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate	2002