toluene 2,4-diisocyanate has been researched along with Asthma, Bronchial in 299 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 101 (33.78) | 18.7374 |
| 1990's | 69 (23.08) | 18.2507 |
| 2000's | 70 (23.41) | 29.6817 |
| 2010's | 47 (15.72) | 24.3611 |
| 2020's | 12 (4.01) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Cai, S; Dong, H; Huang, M; Lan, Z; Li, B; Liu, L; Peng, X; Wang, X; Yu, C; Yuan, Y; Zhao, H; Zhao, W | 1 |
| Plehiers, PM; Schupp, T | 1 |
| Cai, S; Chen, Y; Han, H; Huang, J; Lan, Z; Peng, X; Yang, S; Zhao, H; Zhao, W | 1 |
| Albert Kolstad, H; Baur, X; Dalbøge, A; Ebbehøj, N; Meyer, HW; Schlünssen, V; Sherson, DL; Sigsgaard, T; Ulrik, CS; Zock, JP | 1 |
| Cai, S; Chen, X; Chen, Y; Gong, Z; Huang, J; Li, Y; Peng, X; Wang, Y; Yang, S; Yu, C; Zhao, H; Zhao, W | 1 |
| Bo, C; Jia, Q; Lavin, MF; Peng, C; Sai, L; Shao, H; Wang, X; Yeo, AJ; Yu, G; Zhang, Y | 1 |
| Cui, H; He, J; He, Y; Luo, G; Sun, E; Yang, F; Zhai, Z; Zhao, H; Zhao, W; Zhuang, J; Zhuang, L | 1 |
| Li, J; Shi, J; Song, J; Xu, C; Yao, L | 1 |
| Cai, S; Cheng, W; Cheng, Y; Cui, H; Dong, J; He, Y; Wang, L; Zhao, H; Zhao, W; Zhou, FH | 1 |
| Cai, S; Deng, Z; Dong, H; Huang, G; Su, J; Wang, P; Zhao, H; Zhao, W | 1 |
| Chen, R; Chen, S; Deng, Y; Huang, Y; Song, S; Tao, A | 1 |
| Chang, P; Chen, S; Chen, X; Deng, Y; Li, J; Song, J; Tang, H; Xu, C; Yao, L | 1 |
| Chen, R; Chen, S; Chen, Z; Deng, Y; Li, D; Liang, Z; Liu, S; Yang, K; Yu, L; Zha, S | 1 |
| Cai, S; Dong, H; Le, Y; Lin, Y; Wang, Y; Wu, Y; Xiong, J; Yu, C; Zhao, H; Zhao, W; Zou, F | 1 |
| Ceuppens, J; Cremer, J; Devos, FC; Hoet, PHM; Hoshino, T; Nemery, B; Pollaris, L; Seys, S; Talavera, K; Vanoirbeek, JAJ | 1 |
| Cai, SX; Dong, HM; Huang, GH; Xiong, J; Yao, LH; Yu, CH; Zhao, HJ; Zhao, WQ | 1 |
| Cai, S; Dong, H; Huang, G; Lin, Y; Xiao, G; Xiong, J; Yao, L; Yu, C; Zhao, H; Zhao, W | 1 |
| Cai, S; Deng, Q; Dong, H; Huang, G; Lin, Y; Wang, Y; Xiong, J; Yao, L; Yu, C; Zhao, H; Zhao, W | 1 |
| Ban, GY; Choi, Y; Izuhara, K; Kim, SH; Lee, JH; Park, HS; Shin, YS; Trinh, HKT; Yang, EM; Ye, YM | 1 |
| Chen, R; Chen, S; Chen, X; Huang, P; Liang, Z; Tang, H; Tao, A; Wei, S; Yang, H; Yao, L; Zhang, Q | 1 |
| Chen, R; Chen, S; Chen, X; Huang, P; Liang, Z; Tang, H; Tao, A; Wei, S; Yao, L; Zhang, Q | 1 |
| Chen, R; Chen, S; Guan, H; He, Q; Huang, P; Luo, Y; Peng, G; Tao, A; Wei, S; Yan, J; Yao, L; Zhang, Q; Zou, Z | 1 |
| Cremer, J; Decaesteker, T; Devos, FC; Hoet, PHM; Maes, T; Nemery, B; Pollaris, L; Provoost, S; Seys, S; Van Den Broucke, S; Vande Velde, G; Vanoirbeek, JAJ; Verbeken, E | 1 |
| Bernstein, DI; Boulet, LP; Cartier, A; Gautrin, D; Ho, SM; Lummus, ZL; Ouyang, B; Ying, J | 1 |
| Cai, S; Dong, H; Liang, Z; Liu, L; Lv, Y; Song, J; Tang, H; Zhang, D; Zhao, H; Zou, F; Zou, M | 1 |
| Berckmans, S; Spence, M; Vangronsveld, E | 1 |
| Li, W; Liu, F; Pauluhn, J; Trübel, H; Wang, C | 1 |
| Carlier, V; De Vooght, V; Devos, FC; Haenen, S; Hoet, PH; Nemery, B; Vanoirbeek, JA; Verbeken, E | 1 |
| Patil, UK; Smita, J | 1 |
| Cai, S; Dong, H; Liang, Z; LV, Y; Song, J; Tang, H; Yao, L; Zhao, H; Zou, F | 1 |
| Hu, M; Wang, J; Wang, Q; Xiao, L; Yan, T; Zhu, L | 1 |
| Cai, S; Dong, H; Liang, J; Liu, L; Tang, H; Wu, Y; Yao, L; Zhao, H; Zou, F | 1 |
| Cai, S; Dong, H; Li, W; Liu, L; Song, J; Tang, H; Tong, W; Yao, L; Zhao, H; Zou, F; Zou, M | 1 |
| Cai, S; Dong, H; Song, J; Tang, H; Yao, L; Zhao, H; Zou, F | 2 |
| Bokhari, J; Khan, MR | 1 |
| Clynen, E; De Vooght, V; Haenen, S; Hoet, PH; Nemery, B; Schoofs, L; Vanoirbeek, JA | 2 |
| De Vooght, V; Devos, F; Hoet, PH; Nemery, B; Pollaris, L; Seys, S; Vanoirbeek, JA | 1 |
| Alpizar, YA; Boonen, B; Devos, FC; Hoet, PH; Hox, V; Liston, A; Maes, T; Nemery, B; Pollaris, L; Seys, S; Talavera, K; Vanoirbeek, JA | 1 |
| Cai, S; Dong, H; Liang, J; Liu, L; Tang, H; Yao, L; Zhao, H; Zou, F | 1 |
| Cai, S; Dong, H; Liu, L; Tang, H; Xiong, J; Yao, L; Zhao, H; Zhao, W; Zou, F | 1 |
| Kim, SR; Lee, YC | 1 |
| Cho, BY; Cho, EY; Hong, CS; Kim, CW; Kim, SH; Lee, JE; Park, CS; Park, HS; Shin, ES; Yang, EM | 1 |
| De Vooght, V; Hoet, PH; Nemery, B; Synhaeve, N; Vanoirbeek, JA | 1 |
| De Vooght, V; Haenen, S; Hoet, PH; Nemery, B; Vanoirbeek, JA; Verbeken, E | 2 |
| Choi, JH; Hong, CS; Hur, GY; Jang, AS; Kim, CW; Kim, SH; Lee, HY; Lee, KW; Park, CS; Park, HS | 1 |
| Bucht, A; Gustafsson, A; Koch, BL; Svensson-Elfsmark, L | 1 |
| Hong, CS; Hur, GY; Jang, AS; Kim, CW; Kim, SH; Park, CS; Park, HS; Park, SM; Ye, YM | 1 |
| Cai, SX; Li, W; Peng, H; Tong, W; Zhao, H; Zou, F | 1 |
| del Pozo, V; Fernández-Nieto, M; Pérez-Camo, I; Sánchez, JJ; Sastre, B; Sastre, J | 1 |
| Choi, GS; Jou, I; Kim, SH; Park, HS; Park, SM; Ye, YM | 1 |
| Boland, S; De Vooght, V; Dinsdale, D; Hoet, PH; Hussain, S; Luyts, K; Marano, F; Martens, JA; Nemery, B; Thomassen, LC; Vanoirbeek, JA; Verbeken, E | 1 |
| Beezhold, D; Johnson, VJ; Ruwona, TB; Schmechel, D; Siegel, PD; Simoyi, RH | 1 |
| Clynen, E; De Vooght, V; Haenen, S; Hoet, PH; Maes, E; Nemery, B; Schoofs, L; Vanoirbeek, JA | 1 |
| Boczkowski, J; Lanone, S | 1 |
| Choi, GS; Kim, HY; Kim, JE; Kim, JH; Park, HS; Ye, YM | 1 |
| Moscato, G; Pala, G; Pignatti, P | 1 |
| Gu, Q; Sabbioni, G; Vanimireddy, LR | 1 |
| Choi, GS; Hur, GY; Kim, JH; Kim, SH; Nam, YH; Park, HS; Park, SM | 1 |
| Bernstein, DI; Boulet, LP; Cartier, A; Cruz, MJ; Fluharty, K; Gautrin, D; Germolec, DR; Johnson, VJ; Kissling, GE; Lummus, ZL; Luster, MI; Malo, JL; Munoz, X; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B | 1 |
| Chae, HJ; Jeon, MS; Kim, DI; Kim, SR; Lee, KS; Lee, YC; Park, SJ; Yoo, WH | 1 |
| Pałczyński, C; Swierczyńska-Machura, D | 1 |
| Belmans, J; De Vooght, V; Haenen, S; Hoet, PH; Nemery, B; Opdenakker, G; Smulders, S; Vanoirbeek, JA; Verbeken, E | 1 |
| Nowakowska-Świrta, E; Pałczyński, C; Piasecka-Zelga, J; Świercz, R; Świerczyńska-Machura, D; Walusiak-Skorupa, J | 1 |
| Gordon, T; Redlich, CA; Wisnewski, AV | 1 |
| Karol, MH; Lange, RW; Lemus, R; Luster, MI; Matheson, JM | 2 |
| Folkerts, G; Frossard, N; Haag, M; Le Bouquin, R; Leusink-Muis, T; Lugnier, A; Nijkamp, FP; Pons, F | 1 |
| Brown, WE; Burkert, AL | 1 |
| Conner, PR | 1 |
| Diller, WF | 1 |
| Ott, MG | 1 |
| Liss, GM; Tarlo, SM | 2 |
| Jung, JW; Kim, HA; Kim, SS; Kim, YK; Lee, SK; Nahm, DH; Park, HS | 1 |
| Kim, SS; Lee, SK; Lee, YM; Nahm, DH; Park, HS | 1 |
| Cuesta, J; De Las Heras, M; Fernández-Nieto, M; Novalbos, A; Quirce, S; Sastre, J | 1 |
| Hirayama, Y; Imai, T; Miyayasu, K; Mutoh, S; Ohkubo, Y; Yamagami, K | 1 |
| Bononi, I; Boschetto, P; Maestrelli, P; Mapp, CE; Milan, G; Padoan, M; Piola, C; Pozzato, V; Simoni, M; Zedda, L | 1 |
| Liu, Q; Wisnewski, AV | 1 |
| Jin, SM; Kim, HJ; Lee, KS; Lee, YC | 1 |
| SILVER, HM | 1 |
| Cunningham, AR; Hoet, PH; Mandervelt, C; Nemery, B; Vanhooren, HM; Vanoirbeek, JA; Xu, H | 1 |
| Barton, SJ; Beghé, B; Holgate, ST; Holloway, JW; Howell, WM; Mapp, CE; Moss, CT; Padoan, M | 1 |
| Kim, HA; Lee, SK; Lee, YM; Nahm, DH; Park, HS | 1 |
| Jin, SM; Lee, H; Lee, KS; Lee, YC | 1 |
| Ceuppens, JL; Hoet, PH; Nemery, B; Tarkowski, M; Vanoirbeek, JA; Verbeken, EK | 1 |
| Jin, SM; Kim, SS; Lee, KS; Lee, YC | 1 |
| Choi, JH; Lee, SK; Nahm, DH; Park, HS; Suh, CH; Suh, YJ | 1 |
| Ahn, SW; Choi, JH; Kim, SH; Kim, YS; Nahm, DH; Park, HS; Suh, CH | 1 |
| Johnson, VJ; Luster, MI; Matheson, JM | 1 |
| Johnson, VJ; Luster, MI; Matheson, JM; Vallyathan, V | 1 |
| Bousová, K; Krcmová, I | 1 |
| Hwang, CS; Im, GJ; Jung, HH | 1 |
| Imoto, K; Koda, A; Kohno, S; Nabe, T; Niwa, T; Shinjo, Y; Yamauchi, K | 1 |
| Bonauto, DK; Curwick, CC; Lofgren, DJ; Sumner, AD; Whittaker, SG | 1 |
| Johnson, VJ; Luster, MI; Yucesoy, B | 1 |
| Krone, CA | 1 |
| Choi, IW; Kim, SH; Lee, CM; Lee, HK; Moon, DO; Park, HJ; Park, YM; Roh, HJ | 1 |
| Hong, CS; Kim, CW; Kim, SH; Lee, KW; Nahm, DH; Oh, HB; Park, HS; Shin, ES | 1 |
| Hoet, PH; Nemery, B; Toussaint, G; Vanoirbeek, JA | 1 |
| Baruffini, A; Bernabeo, F; Cerri, S; Mangili, A; Pisati, G | 1 |
| Hong, CS; Kang, YM; Kim, CW; Kim, HM; Kim, HR; Kim, SH; Nahm, DH; Park, CS; Park, HS; Ye, YM | 1 |
| Ceuppens, J; De Vooght, V; Hoet, PH; Mercier, CM; Nemery, B; Tarkowski, M; Vanhooren, HM; Vanoirbeek, JA | 1 |
| Fujimura, M; Furusho, S; Kasahara, K; Kita, T; Myou, S; Nakao, S; Sato, S; Takehara, K; Yasui, M | 1 |
| Jin, SM; Kim, SR; Lee, HK; Lee, KS; Lee, YC; Min, KH; Park, SJ | 1 |
| Kim, CW; Kim, HM; Kim, HR; Nahm, DH; Park, HS; Redlich, CA; Suh, CH; Wisnewski, AV; Ye, YM | 1 |
| Hong, CS; Kim, CW; Kim, HR; Nahm, DH; Park, CS; Park, HS; Suh, CH; Ye, YM | 1 |
| Aardal, NP; Aasen, TB; Bronstad, AM; Elsayed, S; Irgens, A; Sun, LZ; Van Do, T | 1 |
| Arredouani, MS; Fedulov, A; Hubeau, C; Kobzik, L; Lim, RH | 1 |
| Choe, YH; Hong, SJ; Kim, JS; Kim, SR; Lee, KS; Lee, KY; Lee, YC; Lee, YR; Min, KH; Park, SJ | 1 |
| Alenius, H; Laitinen, A; Luukkonen, R; Majuri, ML; Mäntylä, T; Meuronen, A; Nordman, H; Piirilä, PL; Wolff, HJ | 1 |
| Ahn, MH; An, SH; Jang, AS; Kwon, JH; Park, BJ; Park, CS; Park, JW; Rhim, T | 1 |
| Hargreave, FE; Pugsley, SO; Ramsdale, EH | 1 |
| Filieri, M; Gerosa, F; Paggiaro, P; Pezzini, A; Riviera, A; Spiazzi, A; Toma, G; Tridente, G | 1 |
| Baschieri, L; Ferrante, B; Loi, AM; Paggiaro, PL; Pardi, F; Roselli, MG; Rossi, O | 1 |
| Candura, F; Moscato, G | 1 |
| Biscaldi, G; Candura, F; Gherson, G; Moscato, G | 1 |
| Biscaldi, G; Candura, F; Cottica, D; Moscato, G | 1 |
| Morris, MJ; Sugden, E; White, WG; Zapata, E | 1 |
| Kido, T; Teranishi, H; Yamada, Y | 1 |
| Ino, T; Kawai, M; Maekawa, N; Ohata, K; Okamoto, Y; Takeoka, A; Tanaka, K; Watanabe-Kohno, S | 1 |
| Salvaggio, JE; Wilson, MR | 1 |
| Bellone, JD; Kanellakes, TM; Levitz, D; Patterson, R; Pruzansky, JJ; Zeiss, CR | 1 |
| Bernstein, IL; Blanchard, J; Brooks, SM; Gallagher, J; Smith, AB | 1 |
| Check, WA | 1 |
| Butcher, BT | 4 |
| Buckingham, JA; Cromwell, O; Danks, JM; Davies, RJ; Newman-Taylor, AJ | 1 |
| Sepúlveda, R | 1 |
| Baur, X; Fruhmann, G | 1 |
| Reed, CE | 1 |
| Bernstein, IL; Brooks, SM; Gallagher, JS; Tse, CS | 1 |
| Hurst, DJ | 1 |
| Bernstein, IL | 1 |
| Bernstein, IL; Chen, SE | 1 |
| Bernstein, IL; Chen, SE; Splansky, GL; Vinegar, A | 1 |
| Kawai, M; Maekawa, N; Tanaka, K | 2 |
| Baur, X | 1 |
| Burge, PS | 1 |
| Butcher, BT; O'Neil, CE; Reed, MA; Salvaggio, JE | 1 |
| Baschieri, L; Cantalupi, R; Filieri, M; Loi, AM; Paggiaro, PL; Parlanti, A; Roselli, MG; Toma, G | 1 |
| Wang, SR; Wang, SS | 1 |
| Harris, KE; Patterson, R; Zeiss, CR | 1 |
| Daimon, N; Kido, T; Shimizu, T; Teranishi, H; Yamada, Y | 1 |
| Blainey, D; Davies, R | 1 |
| Bernstein, DI; Herd, ZL | 1 |
| di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Occari, P; Pivirotto, F; Saetta, M; Turato, G | 1 |
| Okamoto, Y; Sawahata, T; Sugawara, Y; Tanaka, K | 1 |
| Baur, X; Marczynski, B; Marek, W; Potthast, J; Raulf, M; Tennie, L | 1 |
| Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Pivirotto, F; Saetta, M; Turato, G | 1 |
| D'Elios, MM; De Carli, M; Del Prete, GF; Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Romagnani, S; Saetta, M | 1 |
| Borghesan, F; Calcagni, P; Fabbri, LM; Faggian, D; Maestrelli, P; Mapp, CE; Plebani, M; Saetta, M | 1 |
| Ciaccia, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M | 1 |
| Campbell, TP; Fabbri, L; Karol, MH; Maestrelli, P; Mapp, CE; Saetta, M; Tollerud, DJ | 1 |
| Bacci, E; Bancalari, L; Carrara, M; Dente, FL; Di Franco, A; Giannini, D; Giuntini, C; Paggiaro, PL; Vagaggini, B | 1 |
| Calcagni, PG; Di Stefano, A; Fabbri, LM; Hosselet, JJ; Maestrelli, P; Mapp, CE; Saetta, M; Santonastaso, A | 1 |
| Amitani, R; Kawai, M; Kuze, F; Niimi, A; Tanaka, K; Yamada, K | 2 |
| Bando, T; Fujimura, M; Hirose, J; Matsuda, T; Noda, Y; Ohta, G; Shibata, K | 1 |
| Baruffini, A; Pisati, G; Zedda, S | 1 |
| Rees, D; Roodt, L; Soderlund, N; Wasserfall, C | 1 |
| Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, G; Pivirotto, F; Saetta, M | 1 |
| Cartier, A; Cloutier, Y; Ghezzo, H; Malo, JL; Vandenplas, O | 1 |
| Okamoto, Y; Sawahate, T; Sugawara, Y; Tanaka, K | 1 |
| Boscaro, M; De Marzo, N; Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M | 1 |
| Biscaldi, G; Corsico, A; Dellabianca, A; Gherson, G; Moscato, G; Vinci, G | 1 |
| Amitani, R; Kuze, F; Niimi, A; Tanaka, K; Yamada, K | 1 |
| Chitano, P; Fabbri, LM; Karol, MH; Lapa e Silva, JR; Lucchini, RE; Maestrelli, P; Mapp, CE; Pretolani, M; Rado, V; Saetta, M | 1 |
| Balboni, A; Baricordi, OR; Ciaccia, A; Fabbri, LM; Gandini, E; Mapp, CE | 1 |
| Nahm, DH; Park, HS | 2 |
| Buckley, TL; Davidse, EM; Garssen, J; Nijkamp, FP; Scheerens, H; Van Loveren, H | 1 |
| Karol, MH; Kramarik, JA | 1 |
| Bacci, E; Bancalari, L; Dente, FL; Di Franco, A; Gherson, G; Giannini, D; Giuntini, C; Moscato, G; Paggiaro, PL; Vagaggini, B | 1 |
| Bradley, D | 1 |
| Choi, J; Kim, H; Kim, YD | 1 |
| Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, GF; Occari, P; Papiris, SA; Saetta, M; Turato, G | 1 |
| Hwang, SC; Nahm, DH; Park, HS; Yim, HE | 1 |
| Agami, O; Fireman, E; Kivity, S; Lerman, Y; Veintrov, V | 1 |
| Kim, YT; Lee, M; Park, H; Son, M; Youn, JK | 1 |
| Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL | 1 |
| Desrosiers, M; Ghezzo, H; Leblanc, C; Malo, JL; Nguyen, B | 1 |
| Lee, M; Park, HS; Park, S; Youn, JK | 1 |
| Frossard, N; Kopferschmitt-Kubler, MC; Pauli, G; Rohde, G | 1 |
| Aul, DJ; Bhaumik, A; Brown, WE; Kennedy, AL; Lesage, J; Malo, JL | 1 |
| Kim, HY; Kim, YY; Nahm, DH; Park, HS; Son, JW | 1 |
| Jung, K; Kang, K; Kim, H; Nahm, D; Park, H | 1 |
| Klees, JE; Ott, MG; Poche, SL | 1 |
| Balboni, A; Baricordi, OR; Beghè, B; Fabbri, LM; Jovine, L; Mapp, CE; Padoan, M; Zamorani, G | 1 |
| Fischer, A; Frossard, N; Lugnier, A; Pons, F | 1 |
| Keskinen, HM; Luukkonen, R; Nordman, H; Piirilä, PL; Salo, SP; Tuomi, TO; Tuppurainen, M | 1 |
| Bugler, J; Clark, RL; Meredith, SK | 1 |
| De Zotti, R; Muran, A; Zambon, F | 1 |
| Beasley, BW; Frazier, LM; Mohyuddin, AA; Sharma, GK | 1 |
| Kim, HY; Kim, SS; Lee, SK; Nahm, DH; Park, HS | 2 |
| Estlander, T; Jolanki, R; Kanerva, L; Keskinen, H | 1 |
| Koh, GY; Lee, HB; Lee, YC; Oh, JL; Park, HS; Rhee, YK; Song, CH | 1 |
| Ariizumi, M; Morioka, T; Nong, DX; Todoriki, H; Zheng, KC | 1 |
| Karol, MH; Redlich, CA | 1 |
| Kwak, YG; Lee, YC; Song, CH | 1 |
| Redlich, CA; Wisnewski, AV | 1 |
| Boschetto, P; De Marzo, N; Fryer, AA; Hemmingsen, A; Mapp, CE; Padoan, M; Pozzato, V; Spiteri, MA; Strange, RC | 1 |
| Burge, PS; Harries, MG; O'Brien, I; Taylor, AJ | 1 |
| Peters, JM; Wegman, DH | 1 |
| Aresini, G; Cirla, A; Sala, C; Zedda, S | 1 |
| Hutchcroft, BJ; Pepys, J | 1 |
| Dahl, R; Zetterström, O | 1 |
| Lachnit, V | 1 |
| Carroll, KB; Pepys, J; Secombe, CJ | 1 |
| Alanko, K; Häkkinen, I; Vaaranen, IH | 1 |
| Butcher, BT; Davies, RJ; Salvaggio, JE | 1 |
| Butcher, BT; Davies, RJ; O'Neil, CE; Salvaggio, JE | 1 |
| Abbritti, G; Curradi, F; Siracusa, A | 1 |
| Okada, A; Yamada, Y | 1 |
| Cirla, AM; Sala, C; Zedda, S | 1 |
| Braman, SS; Teplitz, C | 1 |
| Burge, PS; Harries, MG; O'Brien, IM; Pepys, J | 1 |
| Burge, PS; Fawcett, IW; Harries, MG; Newman-Taylor, AJ; O'Brien, IM; Pepys, J | 1 |
| Brethauer, R; Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, J; Martinez-Catinchi, FL; McDonald, EW; Schwartz, HJ | 1 |
| Burge, PS; Harries, MG; O'Brien, IM | 1 |
| Lubach, D | 1 |
| Salvaggio, JE | 1 |
| Chester, EH; Fleming, GM; Gerblich, AA; Horowitz, J; Schwartz, HJ | 1 |
| Baur, X; Fruhmann, G; Römmelt, H | 1 |
| De Marzo, N; Di Stefano, A; Fabbri, LM; Maestrelli, P; Mapp, CE; Milani, GF; Pivirotto, F; Saetta, M | 2 |
| Cartier, A; Grammer, LC; Lesage, J; Malo, JL; Perrault, G; Vandenplas, O | 1 |
| Kim, JW; Kim, SK; Park, HS; Park, JN | 1 |
| Boschetto, P; Ciaccia, A; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Plebani, M; Spinazzi, A | 1 |
| Foster, TA; Glindmeyer, HW; Hughes, JM; Jones, RN; O'Neil, CE; Rando, RJ; Weill, H | 1 |
| Baur, X; Fruhmann, G; Vogelmeier, C | 1 |
| Bossi, MC; Candura, SM; Dellabianca, A; Moscato, G; Vinci, G | 1 |
| Fabbri, LM; Mapp, CE; Picotti, G; Saetta, M | 1 |
| Fabbri, LM; Mapp, CE; Picotti, G | 1 |
| Aoyama, K; Chen, BM; Huang, J; Matsushita, T; Ueda, A; Wang, XP | 1 |
| Berode, M | 1 |
| Liu, JY | 2 |
| Fabbri, LM; Finotto, S; Maestrelli, P; Mapp, CE; Rado, V | 1 |
| Fabbri, LM; Maestrelli, P; Mapp, CE; Saetta, M | 1 |
| Fabbri, LM; Mapp, C | 1 |
| Baik, JH; Cho, DI; Cho, YS; Kim, JW; Park, HS; Park, JN; Rhu, NS | 1 |
| Fabbri, LM | 3 |
| Banks, DE; Barkman, HW; Rando, RJ | 1 |
| Banks, DE; Barkman, HW; Lopez, M; Salvaggio, JE; Sastre, J | 1 |
| Fischbein, A; Luo, JC; Nelsen, KG | 1 |
| Boschetto, P; Fabbri, LM; Mapp, CE; Masiero, M; Milani, GF; Pivirotto, F; Plebani, M; Zocca, E | 1 |
| Bacci, E; Bernard, P; Dente, FL; Giuntini, C; Marchetti, G; Menconi, GF; Paggiaro, P; Paoletti, P; Talini, D | 1 |
| Lee, HS; Phoon, WH; Poh, SC; Wang, YT | 1 |
| Belin, L; Wass, U | 1 |
| Dahl, R; Rasmussen, K | 1 |
| Chiesura-Corona, P; Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Picotti, G; Tossin, L | 1 |
| Corona, PC; Crescioli, S; De Marzo, N; Fabbri, LM; Leproux, GB; Mapp, CE; Tossin, L | 1 |
| Duan, YY | 1 |
| Sheppard, D | 1 |
| Boschetto, P; Bruchi, O; Cappellazzo, G; Fabbri, LM; Mapp, CE; Milani, GF; Pivirotto, F; Zocca, E | 1 |
| Bacci, E; Dente, FL; Fabbri, LM; Giuntini, C; Paggiaro, P; Pulerá, N; Rossi, O; Talini, D | 1 |
| Boschetto, P; Crescioli, S; dal Vecchio, L; de Marzo, N; Fabbri, LM; Mapp, C; Paleari, D | 1 |
| Huang, PH; Lin, JM; Su, SY; Wang, JD; Wu, MC | 1 |
| Boulet, LP | 1 |
| Cirla, AM; Innocenti, A; Mariano, A; Pisati, G | 1 |
| Banks, DE; Rando, RJ | 1 |
| Corona, PC; De Marzo, N; Fabbri, L; Mapp, CE | 1 |
| Bevilacqua, P; Crescioli, S; Danieli, D; Fabbri, LM; Mapp, CE; Meli, S; Saetta, M | 1 |
| Fiorini, R; Governa, M; Valentino, M | 1 |
| Keskinen, H; Nordman, H; Tiikkainen, U; Tupasela, O | 1 |
| Crescioli, S; De Marzo, N; Fabbri, LM; Mapp, CE; Plebani, M; Testi, R | 1 |
| Baschieri, L; Lastrucci, L; Paggiaro, PL; Pardi, F; Pezzini, A; Rossi, O | 1 |
| Fabbri, LM; Hendrick, DJ; Maestrelli, P; Mapp, CE; Polato, R | 1 |
| Boschetto, P; Dal Vecchio, L; Fabbri, LM; Mapp, CE | 1 |
| Burge, PS; Dally, MB; Newman Taylor, AJ; Pickering, CA; Venables, KM | 1 |
| Chiesura-Corona, P; Dal Vecchio, L; de Marzo, N; di Giacomo, GR; Fabbri, LM; Maestrelli, P; Mapp, CE; Zocca, E | 1 |
| Konno, A; Okamoto, Y; Terada, N | 1 |
| Boschetto, P; Dal Vecchio, L; De Marzo, N; Fabbri, LM; Mapp, CE | 1 |
| Bernstein, IL; Brooks, SM; McKay, RT; Moller, DR | 1 |
| Bacci, E; Innocenti, A; Paggiaro, PL; Rossi, O; Talini, D | 1 |
| Bernstein, IL; Brooks, SM; Cassedy, K; Kopp, S; McKay, RT; Moller, DR | 1 |
| Ito, T; Kudo, T; Miki, T; Shima, S; Tachikawa, S; Yoshida, T | 1 |
| Banks, DE; Butcher, BT; Salvaggio, JE | 1 |
| Bacci, E; Lastrucci, L; Paggiaro, PL; Pardi, F; Rossi, O; Talini, D | 1 |
| Broseghini, C; Di Giacomo, GR; Fabbri, LM; Mapp, CE; Omini, C | 1 |
| Comai, M; Governa, M; Rocco, M; Ruschioni, A; Valentino, M | 1 |
| Boschetto, P; Burlina, A; Fabbri, LM; Licata, B; Mapp, CE; Milani, G; Pivirotto, F; Plebani, M; Zocca, E | 1 |
| Ahti, J; Assmuth, T; Haahtela, T; Kurvonen, E; Nieminen, T; Nuorteva, P; Saarainen, T; Seppälä, K; Veide, P; Viholainen, S | 1 |
| Dolovich, J; Grammer, LC; Hargreave, FE; Harris, KE; Patterson, R | 1 |
| Boschetto, P; Dal Vecchio, A; Fabbri, LM; Mapp, CE; Milani, G; Pivirotto, F; Plebani, M; Zocca, E | 1 |
21 review(s) available for toluene 2,4-diisocyanate and Asthma, Bronchial
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
Absorption, distribution, metabolism, and excretion of methylene diphenyl diisocyanate and toluene diisocyanate: Many similarities and few differences.
Topics: Asthma; Chemical Phenomena; Humans; Isocyanates; Toluene 2,4-Diisocyanate | 2022 |
The Relationship Between Potential Occupational Sensitizing Exposures and Asthma: An Overview of Systematic Reviews.
Topics: Animals; Asthma; Occupational Exposure; Systematic Reviews as Topic; Toluene 2,4-Diisocyanate; Wood | 2023 |
PTEN as a unique promising therapeutic target for occupational asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Drug Delivery Systems; Humans; Occupational Diseases; PTEN Phosphohydrolase; Signal Transduction; Toluene 2,4-Diisocyanate | 2008 |
[Pathogenetic and clinical aspects of diisocyanate asthma].
Topics: Air Pollutants, Occupational; Animals; Asthma; Bronchial Hyperreactivity; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; Humans; Immunoglobulin E; Mice; Occupational Diseases; Occupational Exposure; T-Lymphocytes; Toluene 2,4-Diisocyanate | 2012 |
Mouse models of diisocyanate asthma.
Topics: Allergens; Animals; Asthma; Cyanates; Disease Models, Animal; Isocyanates; Mice; Models, Biological; Models, Chemical; Toluene 2,4-Diisocyanate | 2002 |
Biomarkers of toluene diisocyanate exposure.
Topics: Air Pollutants, Occupational; Asthma; Biomarkers; Environmental Monitoring; Humans; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate | 2002 |
Experience with early detection of toluene diisocyanate-associated occupational asthma.
Topics: Air Pollutants, Occupational; Asthma; Environmental Monitoring; Humans; Occupational Diseases; Occupational Exposure; Occupational Health; Surveys and Questionnaires; Toluene 2,4-Diisocyanate | 2002 |
Frequency and trends of occupational asthma due to toluene diisocyanate: a critical review.
Topics: Air Pollutants, Occupational; Asthma; Chemical Industry; Cross-Sectional Studies; Global Health; Humans; Incidence; Longitudinal Studies; Occupational Diseases; Prevalence; Toluene 2,4-Diisocyanate | 2002 |
Occupational asthma, lung function decrement, and toluene diisocyanate (TDI) exposure: a critical review of exposure-response relationships.
Topics: Air Pollutants, Occupational; Asthma; Chemical Industry; Cross-Sectional Studies; Dose-Response Relationship, Drug; Europe; Humans; Longitudinal Studies; Occupational Diseases; Occupational Exposure; Outcome Assessment, Health Care; Respiratory Function Tests; Toluene 2,4-Diisocyanate; United States | 2002 |
Diisocyanate-induced asthma: diagnosis, prognosis, and effects of medical surveillance measures.
Topics: Air Pollutants, Occupational; Asthma; Diagnosis, Differential; Environmental Monitoring; Epidemiological Monitoring; Humans; Occupational Diseases; Ontario; Population Surveillance; Prognosis; Toluene 2,4-Diisocyanate | 2002 |
Recent developments in diisocyanate asthma.
Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate | 2003 |
Isocyanate-induced pulmonary diseases: a current perspective.
Topics: Animals; Asthma; Cyanates; Humans; Lung Diseases; Occupational Diseases; Occupational Health Services; Toluene 2,4-Diisocyanate | 1982 |
Diisocyanate asthma: clinical aspects and immunopathogenesis.
Topics: Animals; Asthma; Humans; Risk Factors; Toluene 2,4-Diisocyanate | 2002 |
Recent developments in diisocyanate asthma.
Topics: Asthma; Cyanates; Genes, MHC Class II; Genetic Predisposition to Disease; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Skin; T-Lymphocytes, Helper-Inducer; Toluene 2,4-Diisocyanate | 2001 |
[The problem of isocyanates in industry. From pathology to control of the risk].
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchitis; Cough; Cyanates; Humans; Industry; Lung Diseases; Occupational Diseases; Polyurethanes; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1978 |
Late asthmatic reactions, airway inflammation and chronic asthma in TDI sensitized subjects.
Topics: Asthma; Chronic Disease; Humans; Inflammation; Occupational Diseases; Prognosis; Respiratory Hypersensitivity; Time Factors; Toluene 2,4-Diisocyanate | 1991 |
Bronchial hyperresponsiveness, airway inflammation and occupational asthma induced by toluene diisocyanate.
Topics: Animals; Asthma; Bronchi; Humans; Inflammation; Occupational Diseases; Prognosis; Toluene 2,4-Diisocyanate | 1991 |
Airway hyperresponsiveness. Mechanisms in experimental models.
Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Humans; Muscle Contraction; Muscle, Smooth; Toluene 2,4-Diisocyanate | 1989 |
Airway inflammation and asthma. Importance of arachidonate metabolites for airway hyperresponsiveness.
Topics: Acetylcholine; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Humans; Inflammation; Ozone; Prednisone; Time Factors; Toluene 2,4-Diisocyanate | 1985 |
Isocyanate-induced respiratory disease.
Topics: Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Occupational Diseases; Respiratory Hypersensitivity; Respiratory System; Toluene 2,4-Diisocyanate | 1986 |
9 trial(s) available for toluene 2,4-diisocyanate and Asthma, Bronchial
| Article | Year |
|---|---|
Protective effect of nifedipine upon specific bronchial responses to isocyanates.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Constriction, Pathologic; Cyanates; Humans; Male; Nifedipine; Occupational Diseases; Random Allocation; Toluene 2,4-Diisocyanate | 1983 |
Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate.
Topics: Adolescent; Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Placebos; Toluene 2,4-Diisocyanate | 1993 |
Theophylline inhibits late asthmatic reactions induced by toluene diisocyanate in sensitised subjects.
Topics: Administration, Inhalation; Administration, Oral; Analysis of Variance; Asthma; Bronchial Provocation Tests; Double-Blind Method; Humans; Placebos; Theophylline; Toluene 2,4-Diisocyanate | 1992 |
Effect of antiasthma drugs on asthmatic reactions induced by toluene diisocyanate in sensitized subjects.
Topics: Adrenergic beta-Agonists; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Cyanates; Humans; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1990 |
Ketotifen does not inhibit asthmatic reactions induced by toluene di-isocyanate in sensitized subjects.
Topics: Asthma; Cyanates; Double-Blind Method; Forced Expiratory Volume; Humans; Hypersensitivity, Delayed; Immunization; Ketotifen; Methacholine Chloride; Methacholine Compounds; Random Allocation; Toluene 2,4-Diisocyanate | 1989 |
Dexamethasone isonicotinate inhibits dual and late asthmatic reactions but not the increase of airway responsiveness induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Dexamethasone; Dexamethasone Isonicotinate; Female; Humans; Male; Toluene 2,4-Diisocyanate | 1989 |
Protective effect of antiasthma drugs on late asthmatic reactions and increased airway responsiveness induced by toluene diisocyanate in sensitized subjects.
Topics: Asthma; Beclomethasone; Bronchial Provocation Tests; Clinical Trials as Topic; Cromolyn Sodium; Cyanates; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Immunization; Lung; Methacholine Chloride; Methacholine Compounds; Placebos; Random Allocation; Respiratory System; Theophylline; Time Factors; Toluene 2,4-Diisocyanate; Verapamil | 1987 |
Dose-dependent inhibitory effect of inhaled beclomethasone on late asthmatic reactions and increased responsiveness to methacholine induced by toluene diisocyanate in sensitised subjects.
Topics: Administration, Inhalation; Adult; Asthma; Beclomethasone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Methacholine Compounds; Middle Aged; Toluene 2,4-Diisocyanate | 1988 |
Prednisone inhibits late asthmatic reactions and airway inflammation induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Albumins; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Exudates and Transudates; Female; Forced Expiratory Volume; Humans; Inflammation; Leukocytosis; Male; Middle Aged; Prednisone; Respiratory System; Therapeutic Irrigation; Toluene 2,4-Diisocyanate | 1987 |
269 other study(ies) available for toluene 2,4-diisocyanate and Asthma, Bronchial
| Article | Year |
|---|---|
RAGE mediates airway inflammation via the HDAC1 pathway in a toluene diisocyanate-induced murine asthma model.
Topics: Animals; Asthma; Benzamides; Cell Line; Cytokines; Depsipeptides; Disease Models, Animal; Histone Deacetylase 1; Humans; Inflammation; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Receptor for Advanced Glycation End Products; Signal Transduction; Toluene 2,4-Diisocyanate | 2022 |
[Inhibition of TAK1 aggravates airway inflammation by increasing RIPK1 activity and promoting macrophage death in a mouse model of toluene diisocyanate-induced asthma].
Topics: Animals; Asthma; Inflammation; Macrophages; Mice; Receptor-Interacting Protein Serine-Threonine Kinases; Respiratory System; Toluene 2,4-Diisocyanate | 2022 |
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Topics: Animals; Asthma; Dexamethasone; Disease Models, Animal; Extracellular Traps; Humans; Inflammation; Interleukin-8; Mice; Steroids; Toluene 2,4-Diisocyanate | 2023 |
Thymic stromal lymphopoietin (TSLP) and Toluene-diisocyanate-induced airway inflammation: Alleviation by TSLP neutralizing antibody.
Topics: Adult; Animals; Anti-Inflammatory Agents; Antibodies, Neutralizing; Asthma; Case-Control Studies; Cross-Sectional Studies; Cytokines; Humans; Immunoglobulin E; Inflammation Mediators; Inhalation Exposure; Interleukin-17; Lung; Male; Mice, Inbred BALB C; Middle Aged; Occupational Exposure; Pneumonia; Signal Transduction; Thymic Stromal Lymphopoietin; Toluene 2,4-Diisocyanate | 2019 |
Bronchial epithelial pyroptosis promotes airway inflammation in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Bronchi; Cell Line; Cytokines; Disease Models, Animal; Epithelial Cells; Humans; Inflammasomes; Inflammation; Male; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 2020 |
Protective effects of N-acetylcysteine on a chemical-induced murine model of asthma.
Topics: Acetylcysteine; Allergens; Animals; Anti-Asthmatic Agents; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Glutathione; Immunoglobulin E; Interleukin-4; Interleukin-5; Leukocyte Count; Lung; Male; Mice, Inbred BALB C; Neutrophils; Superoxide Dismutase; Toluene 2,4-Diisocyanate | 2021 |
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Dexamethasone; Disease Models, Animal; Heterocyclic Compounds, 3-Ring; Immunoglobulin E; Inflammation; Male; Mice; Mice, Inbred BALB C; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Toluene 2,4-Diisocyanate; Treatment Outcome | 2020 |
JNK modulates RAGE/β-catenin signaling and is essential for allergic airway inflammation in asthma.
Topics: Adult; Aged; Animals; Anti-Asthmatic Agents; Asthma; beta Catenin; Bronchoconstriction; Case-Control Studies; Cell Line; Disease Models, Animal; Female; Humans; JNK Mitogen-Activated Protein Kinases; Lung; Male; Mice, Inbred C57BL; Middle Aged; Phosphorylation; Pneumonia; Protein Kinase Inhibitors; Receptor for Advanced Glycation End Products; Serum Albumin, Human; Signal Transduction; Toluene 2,4-Diisocyanate | 2021 |
Anti-DLL4 ameliorates toluene diisocyanate-induced experimental asthma by inhibiting Th17 response.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antibodies; Asthma; Calcium-Binding Proteins; Disease Models, Animal; Female; Immunoglobulin E; Lung; Mice, Inbred BALB C; Spleen; Th17 Cells; Toluene 2,4-Diisocyanate | 2021 |
Distinct roles of PI3Kδ and PI3Kγ in a toluene diisocyanate-induced murine asthma model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Class I Phosphatidylinositol 3-Kinases; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Eosinophils; Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Neutrophils; Toluene 2,4-Diisocyanate | 2021 |
Prevention of IL-6 signaling ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Topics: Animals; Antibodies, Monoclonal, Humanized; Asthma; Disease Models, Animal; Drug Resistance; Humans; Interleukin-6; Mice; Mice, Inbred BALB C; Respiratory Hypersensitivity; Signal Transduction; Toluene 2,4-Diisocyanate | 2022 |
Short Thymic Stromal Lymphopoietin Attenuates Toluene Diisocyanate-induced Airway Inflammation and Inhibits High Mobility Group Box 1-Receptor for Advanced Glycation End Products and Long Thymic Stromal Lymphopoietin Expression.
Topics: Animals; Asthma; Cell Line; Cytokines; Disease Models, Animal; Gene Expression; Glycation End Products, Advanced; HMGB1 Protein; Humans; Male; Mice, Inbred BALB C; Peptides; Phosphorylation; Protein Conformation; Receptor for Advanced Glycation End Products; STAT5 Transcription Factor; Thymic Stromal Lymphopoietin; Toluene 2,4-Diisocyanate | 2017 |
IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice.
Topics: Animals; Antibodies; Asthma; Disease Models, Animal; Immunoglobulin E; Interleukin-13; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Toluene 2,4-Diisocyanate | 2017 |
[Receptor for advanced glycation end products upregulates MUC5AC expression and promotes mucus overproduction in mice with toluene diisocyanate-induced asthma].
Topics: Animals; Asthma; Benzamides; Butadienes; Extracellular Signal-Regulated MAP Kinases; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucus; Nitriles; Random Allocation; Receptor for Advanced Glycation End Products; Toluene 2,4-Diisocyanate | 2017 |
Phosphorylation of low density lipoprotein receptor-related protein 6 is involved in receptor for advanced glycation end product-mediated β-catenin stabilization in a toluene diisocyanate-induced asthma model.
Topics: Animals; Asthma; beta Catenin; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line; Disease Models, Animal; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Lung; Male; Mice, Inbred BALB C; Phosphorylation; Receptor for Advanced Glycation End Products; Toluene 2,4-Diisocyanate | 2018 |
RAGE mediates β-catenin stabilization via activation of the Src/p-Cav-1 axis in a chemical-induced asthma model.
Topics: Animals; Asthma; beta Catenin; Caveolin 1; Disease Models, Animal; Male; Mice, Inbred BALB C; Protein Stability; Receptor for Advanced Glycation End Products; Signal Transduction; src-Family Kinases; Toluene 2,4-Diisocyanate | 2018 |
Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma.
Topics: Adult; Asthma; Asthma, Occupational; Biomarkers; Case-Control Studies; Cell Adhesion Molecules; Endothelial Cells; Female; Humans; Inflammation; Male; Neutrophils; Occupational Diseases; Reactive Oxygen Species; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1 | 2018 |
Transient Receptor Potential Ion Channels Mediate Adherens Junctions Dysfunction in a Toluene Diisocyanate-Induced Murine Asthma Model.
Topics: Acetanilides; Adherens Junctions; Animals; Asthma; beta Catenin; Bronchoalveolar Lavage Fluid; Cadherins; Cytokines; Epithelial Cells; Inflammation; Lung; Mice; Mice, Inbred C57BL; Phosphorylation; Piperidines; Purines; Quinolines; Toluene 2,4-Diisocyanate; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2019 |
IL-17F, rather than IL-17A, underlies airway inflammation in a steroid-insensitive toluene diisocyanate-induced asthma model.
Topics: Animals; Asthma; Bronchodilator Agents; Disease Models, Animal; Drug Resistance; Fluticasone; Glucocorticoids; Interleukin-17; Mice; Mice, Inbred BALB C; Prednisone; Toluene 2,4-Diisocyanate | 2019 |
Blockade of the NLRP3/Caspase-1 Axis Ameliorates Airway Neutrophilic Inflammation in a Toluene Diisocyanate-Induced Murine Asthma Model.
Topics: Airway Remodeling; Animals; Asthma; Caspase 1; Disease Models, Animal; Furans; Heterocyclic Compounds, 4 or More Rings; Indenes; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Neutrophils; NLR Family, Pyrin Domain-Containing 3 Protein; Respiratory Hypersensitivity; Serpins; Sulfonamides; Sulfones; Th17 Cells; Th2 Cells; Toluene 2,4-Diisocyanate; Viral Proteins | 2019 |
Dermal exposure determines the outcome of repeated airway exposure in a long-term chemical-induced asthma-like mouse model.
Topics: Administration, Cutaneous; Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dendritic Cells; Disease Models, Animal; Immunoglobulin E; Immunoglobulin G; Leukocytes; Lung; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Toluene 2,4-Diisocyanate | 2019 |
Interferon-γ promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma.
Topics: Adult; Asthma; DNA; DNA Methylation; Epigenesis, Genetic; Female; Humans; Interferon-gamma; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Promoter Regions, Genetic; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Young Adult | 2013 |
Mechanism of E-cadherin redistribution in bronchial airway epithelial cells in a TDI-induced asthma model.
Topics: Allergens; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cadherins; Cells, Cultured; Dexamethasone; Disease Models, Animal; Drug Antagonism; Epithelial Cells; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Neutrophils; Toluene 2,4-Diisocyanate | 2013 |
Toluene diisocyanate emission to air and migration to a surface from a flexible polyurethane foam.
Topics: Air Pollutants, Occupational; Asthma; Dermis; Humans; Inhalation Exposure; Occupational Exposure; Piperazines; Polyurethanes; Toluene 2,4-Diisocyanate | 2013 |
Rat models of acute lung injury: exhaled nitric oxide as a sensitive, noninvasive real-time biomarker of prognosis and efficacy of intervention.
Topics: Acute Lung Injury; Animals; Asthma; Biomarkers; Breath Tests; Carbon Dioxide; Chlorine; Disease Models, Animal; Equipment Design; Exhalation; Inhalation Exposure; Lipopolysaccharides; Male; Nitric Oxide; Phosgene; Plethysmography, Impedance; Rats; Rats, Inbred BN; Rats, Wistar; Toluene 2,4-Diisocyanate | 2013 |
B-lymphocytes as key players in chemical-induced asthma.
Topics: Animals; Asthma; B-Lymphocyte Subsets; B7-1 Antigen; B7-2 Antigen; Bronchoconstrictor Agents; CD40 Antigens; Disease Models, Animal; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, SCID; Toluene 2,4-Diisocyanate | 2013 |
Effect of Ipomea carnea Jacq. flowers on hematological changes in toluene diisocyanate-induced inflammation in Wistar rats.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Eosinophils; Female; Flowers; Hematology; Inflammation; Ipomoea; Leukocyte Count; Male; Molecular Structure; Neutrophils; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Stigmasterol; Toluene 2,4-Diisocyanate | 2014 |
Ethyl pyruvate decreases airway neutrophil infiltration partly through a high mobility group box 1-dependent mechanism in a chemical-induced murine asthma model.
Topics: Animals; Asthma; Cell Count; Cell Movement; Cells, Cultured; Chemokine CXCL2; Disease Models, Animal; HMGB1 Protein; Lung; Male; Mice; Neutrophils; Pyruvates; Receptors, Interleukin-8B; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2014 |
The effect of synthetic salidroside on cytokines and airway inflammation of asthma induced by diisocyanate (TDI) in mice by regulating GATA3/T-bet.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Eosinophils; Female; GATA3 Transcription Factor; Glucosides; Mice; Mice, Inbred BALB C; Phenols; T-Box Domain Proteins; Toluene 2,4-Diisocyanate | 2015 |
Phosphatidylinositol 3-kinases pathway mediates lung caspase-1 activation and high mobility group box 1 production in a toluene-diisocyanate induced murine asthma model.
Topics: Administration, Inhalation; Airway Resistance; Animals; Asthma; Carrier Proteins; Caspase 1; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; HMGB1 Protein; Inflammasomes; Lung; Male; Mice, Inbred BALB C; Neutrophil Infiltration; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Transport; Random Allocation; Respiratory Mucosa; Signal Transduction; Specific Pathogen-Free Organisms; Toluene 2,4-Diisocyanate | 2015 |
1,25-Dihydroxyvitamin D3 prevents toluene diisocyanate-induced airway epithelial barrier disruption.
Topics: Animals; Asthma; Cadherins; Calcitriol; Cell Line; Cell Membrane Permeability; Electric Impedance; Eosinophils; Extracellular Signal-Regulated MAP Kinases; Humans; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-4; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Occludin; Respiratory Mucosa; Tight Junctions; Toluene 2,4-Diisocyanate; Zonula Occludens-1 Protein | 2015 |
Phosphatidylinositol 3-Kinase Mediates β-Catenin Dysfunction of Airway Epithelium in a Toluene Diisocyanate-Induced Murine Asthma Model.
Topics: Animals; Asthma; beta Catenin; Cadherins; Chromones; Enzyme Inhibitors; Interleukins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Respiratory Mucosa; Signal Transduction; Toluene 2,4-Diisocyanate | 2015 |
Evaluation of anti-asthmatic and antioxidant potential of Boerhavia procumbens in toluene diisocyanate (TDI) treated rats.
Topics: Animals; Anti-Asthmatic Agents; Antioxidants; Asthma; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen Peroxide; Male; Nyctaginaceae; Plant Extracts; Rats; Rats, Sprague-Dawley; Toluene 2,4-Diisocyanate | 2015 |
Chicken IgY facilitates allergic airway inflammation in a chemical-induced murine asthma model by potentiating IL-4 release.
Topics: Animals; Asthma; Chickens; Disease Models, Animal; HMGB1 Protein; Immunoglobulins; Interleukin-4; Male; Mice; Mice, Inbred BALB C; Neutrophils; Toluene 2,4-Diisocyanate | 2015 |
Proteomic Alterations in B Lymphocytes of Sensitized Mice in a Model of Chemical-Induced Asthma.
Topics: Animals; Asthma; B-Lymphocytes; Male; Mice, Inbred BALB C; Mice, Knockout; Mice, SCID; Proteome; Toluene 2,4-Diisocyanate | 2015 |
Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model.
Topics: Air Pollutants, Occupational; Animals; Asthma; Cross Reactions; Disease Models, Animal; Immunoglobulin E; Isocyanates; Male; Mice, Inbred C57BL; Th1-Th2 Balance; Toluene 2,4-Diisocyanate | 2016 |
Neuro-immune interactions in chemical-induced airway hyperreactivity.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Calcium; CHO Cells; Cricetulus; Inflammation; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Patch-Clamp Techniques; Sensory Receptor Cells; Toluene 2,4-Diisocyanate; TRPA1 Cation Channel; TRPV Cation Channels | 2016 |
The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model.
Topics: Animals; Asthma; beta Catenin; Disease Models, Animal; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Male; Mice; Mice, Inbred BALB C; Receptor for Advanced Glycation End Products; Structure-Activity Relationship; Toluene 2,4-Diisocyanate | 2016 |
Blockade of β-catenin signaling attenuates toluene diisocyanate-induced experimental asthma.
Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; beta Catenin; Biomarkers; Bridged Bicyclo Compounds, Heterocyclic; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Heterocyclic Compounds, 3-Ring; Immunoglobulin E; Immunohistochemistry; Lymphocytes; Male; Mice; Molecular Targeted Therapy; Pyrimidinones; Signal Transduction; Toluene 2,4-Diisocyanate | 2017 |
Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.
Topics: Adult; alpha Catenin; Asthma; B-Lymphocytes; Bronchial Provocation Tests; Cell Line, Transformed; Female; Gene Expression; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Immunoglobulin E; Immunoglobulin G; Keratin-19; Male; Middle Aged; Occupational Diseases; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Risk Factors; Toluene 2,4-Diisocyanate | 2009 |
Is toluene diamine a sensitizer and is there cross-reactivity between toluene diamine and toluene diisocyanate?
Topics: Animals; Antigens, CD; Asthma; Cells, Cultured; Cross Reactions; Cytokines; Disease Models, Animal; Immunoglobulins; Local Lymph Node Assay; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Phenylenediamines; Statistics, Nonparametric; Toluene 2,4-Diisocyanate | 2009 |
Oropharyngeal aspiration: an alternative route for challenging in a mouse model of chemical-induced asthma.
Topics: Administration, Intranasal; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytokines; Disease Models, Animal; Eosinophils; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Respiratory Aspiration; Toluene 2,4-Diisocyanate; Up-Regulation | 2009 |
The HLA DRB1*1501-DQB1*0602-DPB1*0501 haplotype is a risk factor for toluene diisocyanate-induced occupational asthma.
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Gene Frequency; Haplotypes; HLA-DP Antigens; HLA-DP beta-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunoglobulin E; Korea; Male; Membrane Glycoproteins; Middle Aged; Occupational Diseases; Risk Factors; Toluene 2,4-Diisocyanate | 2009 |
Rats repeatedly exposed to toluene diisocyanate exhibit immune reactivity against methyl isocyanate-protein conjugates.
Topics: Administration, Inhalation; Animals; Asthma; Epitopes; Female; Humans; Immunoglobulin G; Isocyanates; Male; Multiprotein Complexes; Neutrophil Infiltration; Occupational Exposure; Rats; Rats, Inbred F344; Rats, Wistar; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Weight Gain | 2009 |
Tissue transglutaminase can be involved in airway inflammation of toluene diisocyanate-induced occupational asthma.
Topics: Adult; Asthma; Case-Control Studies; Female; GTP-Binding Proteins; Humans; Immunoglobulin E; Immunoglobulin G; Inflammation; Male; Middle Aged; Occupational Diseases; Protein Glutamine gamma Glutamyltransferase 2; Reactive Oxygen Species; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Transglutaminases; Young Adult | 2009 |
Toluene diisocyanate enhances human bronchial epithelial cells' permeability partly through the vascular endothelial growth factor pathway.
Topics: Antibodies, Monoclonal; Asthma; Bronchi; Cell Line; Cell Membrane; Epithelial Cells; Humans; Permeability; Respiratory Mucosa; Serum Albumin; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A | 2009 |
Serum ferritin and transferrin levels are not serologic markers of toluene diisocyanate-induced occupational asthma.
Topics: Adult; Area Under Curve; Asthma; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Ferritins; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate; Transferrin | 2010 |
Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma.
Topics: Active Transport, Cell Nucleus; Adult; Apoferritins; Asthma; Catalase; Cell Line; Cell Nucleus; Chemical Industry; Female; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; Humans; Hypoglycemic Agents; Immunologic Factors; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase Kinases; NF-E2-Related Factor 2; Occupational Exposure; Peroxiredoxins; PPAR gamma; Prostaglandin D2; Respiratory Mucosa; Rosiglitazone; Thiazolidinediones; Thioredoxins; Toluene 2,4-Diisocyanate; Transferrin | 2010 |
Lung exposure to nanoparticles modulates an asthmatic response in a mouse model.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Gold; Immunoglobulin E; Lung; Macrophages; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neutrophils; Pulmonary Edema; Titanium; Toluene 2,4-Diisocyanate | 2011 |
Monoclonal antibodies against toluene diisocyanate haptenated proteins from vapor-exposed mice.
Topics: Administration, Inhalation; Animals; Antibodies, Monoclonal; Antibody Specificity; Asthma; Enzyme-Linked Immunosorbent Assay; Female; Haptens; Humans; Hybridomas; Immunoblotting; Immunoglobulin M; Isocyanates; Mice; Mice, Inbred C57BL; Serum Albumin; Toluene 2,4-Diisocyanate | 2010 |
Proteome analysis of multiple compartments in a mouse model of chemical-induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Mass Spectrometry; Methacholine Chloride; Mice; Neutrophils; Oxidative Stress; Proteome; Toluene 2,4-Diisocyanate | 2010 |
Successful transfer of chemical-induced asthma by adoptive transfer of low amounts of lymphocytes in a mouse model.
Topics: Adoptive Transfer; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Immunoglobulin E; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate | 2011 |
Titanium and gold nanoparticles in asthma: the bad and the ugly.
Topics: Animals; Asthma; Gold; Humans; Immunity, Cellular; Immunoglobulin E; Metal Nanoparticles; Mice; Titanium; Toluene 2,4-Diisocyanate | 2011 |
Serum cytokines markers in toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Biomarkers; Chemical Industry; Early Diagnosis; Female; Humans; Male; Matrix Metalloproteinase 9; Occupational Diseases; Occupational Exposure; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2011 |
Occupational exposure to toluene diisocyanate and neutrophilic bronchitis without asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchitis; Chronic Disease; Cough; Female; Humans; Lymphocyte Count; Neutrophils; Occupational Diseases; Occupational Exposure; Spirometry; Sputum; Toluene 2,4-Diisocyanate | 2011 |
Determination of isocyanate specific albumin-adducts in workers exposed to toluene diisocyanates.
Topics: Adult; Air Pollutants, Occupational; Albumins; Asthma; Biomarkers; Chemical Industry; Chromatography, Liquid; Humans; Isocyanates; Lysine; Mass Spectrometry; Middle Aged; Toluene 2,4-Diisocyanate | 2012 |
Role of vitamin D-binding protein in isocyanate-induced occupational asthma.
Topics: Adult; Animals; Asthma; Cell Line; Epithelial Cells; Female; Gene Expression; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Rats; Toluene 2,4-Diisocyanate; Vitamin D-Binding Protein | 2012 |
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.
Topics: Adult; Antioxidants; Asthma; Canada; Cyanates; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Isocyanates; Male; Toluene 2,4-Diisocyanate | 2012 |
AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Asthma; Basic Helix-Loop-Helix Transcription Factors; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cytokines; Disease Models, Animal; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred BALB C; Pneumonia; Reactive Oxygen Species; Ribonucleotides; Signal Transduction; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A | 2012 |
Proteome changes in auricular lymph nodes and serum after dermal sensitization to toluene diisocyanate in mice.
Topics: Animals; Asthma; Blood Proteins; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Proteome; Signal Transduction; Toluene 2,4-Diisocyanate; Two-Dimensional Difference Gel Electrophoresis | 2012 |
Neutrophil and eosinophil granulocytes as key players in a mouse model of chemical-induced asthma.
Topics: Animals; Asthma; Body Weight; Cyclophosphamide; Eosinophils; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Neutrophils; Toluene 2,4-Diisocyanate | 2013 |
Immunological determinants in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Female; Inhalation Exposure; Leukocytes; Macrophages; Mice; Toluene 2,4-Diisocyanate | 2012 |
Role of tumor necrosis factor in toluene diisocyanate asthma.
Topics: Allergens; Animals; Antigens, CD; Asthma; B7-2 Antigen; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunoglobulin E; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lymph Nodes; Membrane Glycoproteins; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Occupational Exposure; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2002 |
Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Cytochrome P-450 CYP1A1; Male; Methylcholanthrene; Mice; Mice, Inbred BALB C; Microsomes, Liver; RNA, Messenger; Toluene 2,4-Diisocyanate | 2002 |
Metalloproteinase-9 is increased after toluene diisocyanate exposure in the induced sputum from patients with toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Female; Gelatinases; Humans; Irritants; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methacholine Chloride; Middle Aged; Occupational Diseases; Sputum; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate | 2003 |
Longitudinal study of specific antibodies to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in patients with TDI-induced asthma.
Topics: Adult; Asthma; Biomarkers; Humans; Immunoglobulin E; Immunoglobulin G; Longitudinal Studies; Male; Middle Aged; Serum Albumin; Toluene 2,4-Diisocyanate | 2002 |
Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyanates; False Negative Reactions; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Middle Aged; Monitoring, Physiologic; Occupational Diseases; Prospective Studies; Toluene 2,4-Diisocyanate | 2003 |
Effect of FK3657, a non-peptide bradykinin B2 receptor antagonist, on allergic airway disease models.
Topics: Animals; Asthma; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Capillary Permeability; Guinea Pigs; Male; Nasal Mucosa; Ovalbumin; Plasma; Quinolines; Toluene 2,4-Diisocyanate; Trachea | 2003 |
Long-term follow-up of toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Follow-Up Studies; Humans; Logistic Models; Longitudinal Studies; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Occupational Exposure; Prognosis; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 2003 |
Matrix metalloproteinase inhibitor regulates inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Movement; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-4; Leukocytes; Lung; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; RNA, Messenger; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2003 |
TOLUENE DIISOCYANATE ASTHMA. REVIEW AND CASE REPORT WITH RESPONSE TO STEROIDS.
Topics: Asthma; Bronchial Spasm; Cyanates; Humans; Occupational Diseases; Respiratory Function Tests; Steroids; Toluene; Toluene 2,4-Diisocyanate; Toxicology | 1963 |
Validity of methods to predict the respiratory sensitizing potential of chemicals: A study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Allergens; Animals; Asthma; Bronchoalveolar Lavage; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Female; Immunoglobulin E; Local Lymph Node Assay; Lung; Lymph Nodes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Occupational Exposure; Oxazolone; Piperidines; Predictive Value of Tests; Structure-Activity Relationship; Toluene 2,4-Diisocyanate; Triazines | 2003 |
Lack of association of HLA class I genes and TNF alpha-308 polymorphism in toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Case-Control Studies; Female; Genetic Predisposition to Disease; Histocompatibility Antigens Class I; Humans; Male; Middle Aged; Occupational Diseases; Polymorphism, Genetic; Probability; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2004 |
Exposure to toluene diisocyanate (TDI) induces IL-8 production from bronchial epithelial cells: effect of pro-inflammatory cytokines.
Topics: Asthma; Bronchi; Cell Line; Dexamethasone; Epithelial Cells; Glucocorticoids; Humans; Interleukin-8; Leukocytes, Mononuclear; Toluene 2,4-Diisocyanate | 2003 |
Imbalance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Blotting, Western; Bronchi; Bronchoalveolar Lavage Fluid; Female; Immunoblotting; Immunohistochemistry; Lung; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Models, Animal; Occupational Diseases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solvents; Tissue Inhibitor of Metalloproteinase-1; Toluene 2,4-Diisocyanate | 2004 |
Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice.
Topics: Administration, Intranasal; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Dermatitis, Allergic Contact; Disease Models, Animal; Immunoglobulin E; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Occupational Exposure; Plethysmography, Whole Body; Respiratory Mechanics; Toluene 2,4-Diisocyanate | 2004 |
Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Anti-Bacterial Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Doxycycline; Female; Inflammation; Lung; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Ovalbumin; Protease Inhibitors; RNA, Messenger; Toluene 2,4-Diisocyanate | 2004 |
Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients.
Topics: Adult; Asthma; Bronchi; Enzyme-Linked Immunosorbent Assay; Exercise; Humans; Methacholine Chloride; Middle Aged; Placebos; Sputum; Time Factors; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A | 2004 |
Increased levels of IgG to cytokeratin 19 in sera of patients with toluene diisocyanate-induced asthma.
Topics: Adult; Allergens; Antibody Specificity; Asthma; Autoantibodies; Autoantigens; Bronchi; Bronchial Provocation Tests; Cell Line, Transformed; Cells, Cultured; Coculture Techniques; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Gene Expression Profiling; Humans; Immunoconjugates; Immunoglobulin E; Immunoglobulin G; Keratins; Male; Methacholine Chloride; Middle Aged; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Serum Albumin; Toluene 2,4-Diisocyanate | 2004 |
Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Enzyme-Linked Immunosorbent Assay; Eosinophils; Immunoglobulin E; Mice; Mice, Inbred C57BL; Mice, Knockout; Occupational Diseases; Peroxidases; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Th2 Cells; Toluene 2,4-Diisocyanate | 2005 |
Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma.
Topics: Adoptive Transfer; Aerosols; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dermatitis, Contact; Eosinophils; Gene Expression; Immunoglobulin E; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peroxidase; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Toluene 2,4-Diisocyanate | 2005 |
[Diisocyanate exposure as a cause of occupational asthma].
Topics: Adult; Asthma; Cyanates; Humans; Middle Aged; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate | 2004 |
Quantitative expression levels of regulated on activation, normal T cell expressed and secreted and eotaxin transcripts in toluene diisocyanate-induced allergic rats.
Topics: Animals; Asthma; beta 2-Microglobulin; Chemokine CCL11; Chemokine CCL5; Chemokines, CC; Eosinophilia; Gene Expression Regulation; Leukocyte Count; Lymphocyte Activation; Male; Nasal Mucosa; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Reverse Transcriptase Polymerase Chain Reaction; Rhinitis, Allergic, Perennial; RNA, Messenger; T-Lymphocytes; Toluene 2,4-Diisocyanate; Vascular Cell Adhesion Molecule-1 | 2005 |
Delayed-type asthmatic response induced by repeated intratracheal exposure to toluene-2,4-diisocyanate in guinea pigs.
Topics: Airway Resistance; Albumins; Albuterol; Allergens; Animals; Asthma; Chromones; Dexamethasone; Disease Models, Animal; Fucose; Guinea Pigs; Hypersensitivity, Delayed; Immunoglobulin E; Immunoglobulin G; Male; Time Factors; Toluene 2,4-Diisocyanate; Trachea | 2005 |
Work-related asthma in the spray-on truck bed lining industry.
Topics: Adolescent; Adult; Asthma; Automobiles; Humans; Incidence; Male; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Washington; Workers' Compensation | 2005 |
Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Antibody Formation; Antibody Specificity; Asthma; Disease Models, Animal; Female; Inflammation; Interleukin-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Interleukin-1; Respiratory Hypersensitivity; Signal Transduction; Toluene 2,4-Diisocyanate; Up-Regulation | 2005 |
Diisocyanates and nonoccupational disease: a review.
Topics: Asthma; Child; Cyanates; Environmental Exposure; Household Products; Humans; Polyurethanes; Toluene 2,4-Diisocyanate | 2004 |
Epigallocatechin-3-gallate protects toluene diisocyanate-induced airway inflammation in a murine model of asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Catechin; Disease Models, Animal; Gene Expression Regulation; Inflammation; Interleukin-5; Matrix Metalloproteinase 9; Mice; Reactive Oxygen Species; Respiratory System; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2006 |
HLA DRB1*15-DPB1*05 haplotype: a susceptible gene marker for isocyanate-induced occupational asthma?
Topics: Adult; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Female; Haplotypes; HLA-DP Antigens; HLA-DP beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Korea; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Occupational Exposure; Skin Tests; Toluene 2,4-Diisocyanate | 2006 |
Reduced exercise capacity in a mouse model of asthma.
Topics: Animals; Asthma; Exercise Tolerance; Male; Mice; Mice, Inbred BALB C; Models, Animal; Toluene 2,4-Diisocyanate | 2006 |
Rechallenging subjects with occupational asthma due to toluene diisocyanate (TDI), after long-term removal from exposure.
Topics: Adult; Asthma; Bronchial Provocation Tests; Follow-Up Studies; Forced Expiratory Volume; Humans; Occupational Diseases; Occupational Exposure; Recovery of Function; Toluene 2,4-Diisocyanate | 2007 |
Relationship between neurokinin 2 receptor gene polymorphisms and serum vascular endothelial growth factor levels in patients with toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Immunoglobulin E; Male; Middle Aged; Occupational Diseases; Polymorphism, Single Nucleotide; Receptors, Neurokinin-2; Toluene 2,4-Diisocyanate; Vascular Endothelial Growth Factor A | 2006 |
Immunological determinants of ventilatory changes induced in mice by dermal sensitization and respiratory challenge with toluene diisocyanate.
Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Immunoglobulins; In Vitro Techniques; Lymphocytes; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, SCID; Skin; Toluene 2,4-Diisocyanate | 2007 |
Role of intercellular adhesion molecule-1 in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Chemokine CXCL2; Chemokines; Immunoglobulin E; Immunoglobulin G; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-4; Interleukin-5; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2006 |
Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma.
Topics: Animals; Asthma; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Inflammation; Mice; NF-kappa B; PPAR gamma; Respiratory System; Th2 Cells; Toluene 2,4-Diisocyanate; Transforming Growth Factor beta1 | 2006 |
Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma.
Topics: Adult; Albumins; Antigens; Asthma; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Immunoglobulin G; Male; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Toluene 2,4-Diisocyanate | 2006 |
Cytokeratin autoantibodies: useful serologic markers for toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Autoantibodies; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoblotting; Keratin-18; Keratin-19; Keratin-8; Keratins; Male; Middle Aged; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate | 2006 |
Airway inflammation and bronchial remodelling in toluene diisocyanate-exposed BALB/c mouse model.
Topics: Alum Compounds; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Inflammation; Interleukin-4; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Th2 Cells; Toluene 2,4-Diisocyanate | 2007 |
Maternal allergic contact dermatitis causes increased asthma risk in offspring.
Topics: Animals; Asthma; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Disease Susceptibility; Female; Gene Expression Regulation; Interleukin-4; Irritants; Lung; Male; Maternal Exposure; Mice; Mice, Inbred BALB C; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Th1 Cells; Th2 Cells; Toluene 2,4-Diisocyanate | 2007 |
PTEN down-regulates IL-17 expression in a murine model of toluene diisocyanate-induced airway disease.
Topics: Adenoviridae; Animals; Asthma; Disease Models, Animal; Down-Regulation; Female; Inflammation; Inhalation Exposure; Interleukin-17; Mice; Mice, Inbred BALB C; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Sulfones; Toluene 2,4-Diisocyanate | 2007 |
Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure.
Topics: Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoscopy; Female; Humans; Inflammation; Interleukin-4; Macrophages; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Respiratory Mucosa; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2008 |
Asp-Tyr-Leu-Lys tetrapeptide inhibits airway inflammation in toluene-2,4-diisocyanate-induced asthma mice.
Topics: Actins; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cattle; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Immunohistochemistry; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucin 5AC; Mucins; Oligopeptides; Proliferating Cell Nuclear Antigen; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Trachea; Vascular Endothelial Growth Factor A | 2008 |
Occupational asthma without bronchial hyperresponsiveness.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Peak Expiratory Flow Rate; Pulmonary Ventilation; Toluene 2,4-Diisocyanate | 1984 |
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 1984 |
Follow-up study of patients with respiratory disease due to toluene diisocyanate (TDI).
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1984 |
Do amines induce occupational asthma in workers manufacturing polyurethane foams?
Topics: Amines; Asthma; Chemical Industry; Humans; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Phenylenediamines; Polyurethanes; Toluene 2,4-Diisocyanate | 1984 |
Specific bronchial provocation tests in occupational asthma and methods of stimulation: case report.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Occupational Diseases; Paint; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1983 |
Isocyanate-induced asthma in a car factory.
Topics: Asthma; Automobiles; Cyanates; Female; Humans; Immunoglobulin E; Occupational Diseases; Occupations; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1980 |
[Toluene-diisocyanate-induced asthma. 2. Histamine liberation test using leukocytes from toluene-diisocyanate sensitized guinea pigs].
Topics: Animals; Asthma; Cyanates; Female; Guinea Pigs; Histamine Release; Leukocytes; Toluene 2,4-Diisocyanate | 1983 |
[Nasal allergy observed in an asthma model by toluene diisocyanate (TDI)].
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Guinea Pigs; Histamine Release; Rhinitis, Allergic, Perennial; Toluene 2,4-Diisocyanate | 1984 |
Activation of the alternative pathway of complement: a mechanism in search of diseases.
Topics: Anaphylaxis; Asthma; Byssinosis; Complement Activation; Complement C1s; Complement C3b; Complement C3b Inactivator Proteins; Complement Pathway, Alternative; Humans; Inflammation; Toluene 2,4-Diisocyanate | 1980 |
Immunoglobulin E-mediated asthma and hypersensitivity pneumonitis with precipitating anti-hapten antibodies due to diphenylmethane diisocyanate (MDI) exposure.
Topics: Adult; Alveolitis, Extrinsic Allergic; Antibodies; Asthma; Benzhydryl Compounds; Cross Reactions; Cyanates; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Middle Aged; Serum Albumin; Toluene 2,4-Diisocyanate | 1980 |
Absence of airway hyperreactivity to methacholine in a worker sensitized to toluene diisocyanate (TDI).
Topics: Adult; Airway Obstruction; Asthma; Bronchi; Cyanates; Dose-Response Relationship, Drug; Female; Humans; Methacholine Compounds; Occupational Diseases; Toluene 2,4-Diisocyanate | 1980 |
Work-related asthma comes out of hiding.
Topics: Allergens; Asthma; Cyanates; Molecular Weight; Occupational Diseases; Phthalic Anhydrides; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1980 |
Approaches to the understanding of mechanisms in occupational asthma.
Topics: Allergens; Asthma; Humans; Lymphocytes; Occupational Diseases; Receptors, Adrenergic, beta; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1980 |
Toluene-diisocyanate induced asthma: evaluation of antibodies in the serum of affected workers against a tolyl mono-isocyanate protein conjugate.
Topics: Antibody Formation; Antibody Specificity; Asthma; Cyanates; Humans; Immunoglobulin E; Isocyanates; Occupational Diseases; Radioimmunoassay; Serum Albumin; Toluene 2,4-Diisocyanate | 1981 |
[Occupational asthma (author's transl)].
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1980 |
Specific IgE antibodies in patients with isocyanate asthma.
Topics: Antibodies; Asthma; Benzhydryl Compounds; Cyanates; Humans; Immunoglobulin E; Isocyanates; Toluene 2,4-Diisocyanate | 1981 |
Occupational asthma: a challenge in patient management and community care.
Topics: Asthma; Environmental Exposure; Humans; Immunization; Immunoglobulin E; Occupational Diseases; Occupational Medicine; Skin Tests; Toluene 2,4-Diisocyanate; United States | 1981 |
Diverse profiles of immunoreactivity in toluene diisocyanate (TDI) asthma.
Topics: Adult; Antigen-Antibody Reactions; Asthma; Cell Migration Inhibition; Cyanates; Female; Humans; Immunity, Cellular; Lymphokines; Male; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate | 1981 |
Occupational asthma.
Topics: Animals; Asthma; Bronchi; Cyanates; Dogs; Humans; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1982 |
The guinea pig model of diisocyanate sensitization. I. Immunologic studies.
Topics: Animals; Asthma; Cross Reactions; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Humans; Immunization; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Passive Cutaneous Anaphylaxis; Serum Albumin; Toluene 2,4-Diisocyanate; Transferrin | 1982 |
The guinea pig model of diisocyanate sensitization. II. Physiologic studies.
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Immune Sera; Immunoglobulin E; Isocyanates; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Transferrin | 1982 |
Occupational asthma.
Topics: Asthma; Cyanates; Humans; Male; Middle Aged; Occupational Diseases; Pneumoconiosis; Toluene 2,4-Diisocyanate | 1982 |
[On the induction of asthma in guinea pigs by toluene diisocyanate (TDI)].
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Guinea Pigs; Toluene 2,4-Diisocyanate | 1982 |
Immunologic cross-reactivity between different albumin-bound isocyanates.
Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1983 |
Isocyanate induced asthma.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate | 1982 |
Mechanisms of isocyanate induced asthma.
Topics: Asthma; Cyanates; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Immunoglobulin E; Lymphocytes; Occupational Diseases; Radioimmunoassay; Skin Tests; Toluene 2,4-Diisocyanate | 1982 |
Non-specific bronchial hyper-reactivity in workers exposed to toluene di-isocyanate, diphenyl methane di-isocyanate and colophony.
Topics: Asthma; Bronchi; Cyanates; Electronics; Environmental Exposure; Histamine; Humans; Isocyanates; Occupational Diseases; Resins, Plant; Toluene 2,4-Diisocyanate | 1982 |
Radioallergosorbent testing with p-tolyl monoisocyanate in toluene diisocyanate workers.
Topics: Asthma; Cyanates; Dermatitis, Atopic; Drug Hypersensitivity; False Positive Reactions; Humans; Immunoglobulin E; Isocyanates; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1983 |
Absence of IgG antibodies to TDI-HSA in a radioimmunological study.
Topics: Animals; Asthma; Cyanates; Humans; Immunoglobulin G; Occupational Diseases; Rabbits; Radioimmunoassay; Respiratory Hypersensitivity; Serum Albumin; Toluene 2,4-Diisocyanate | 1983 |
[Asthma induced by diphenylmethane diisocyanate].
Topics: Adult; Asthma; Chemical Phenomena; Chemistry; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Risk; Toluene 2,4-Diisocyanate | 1983 |
Immunologic and respiratory responses to airway challenges of dogs with toluene diisocyanate.
Topics: Animals; Antibody Formation; Asthma; Bronchial Provocation Tests; Cyanates; Dogs; Forced Expiratory Flow Rates; Hypersensitivity, Immediate; Immunoglobulin A; Immunoglobulin E; Immunoglobulin G; Immunoglobulin M; Lymphocyte Activation; Tidal Volume; Toluene 2,4-Diisocyanate | 1983 |
[Toluene diisocyanate asthma. 1. Clinico-immunological evaluation].
Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Male; Occupational Diseases; Radioallergosorbent Test; Toluene 2,4-Diisocyanate | 1983 |
Experimental model of asthma by toluene diisocyanate (TDI).
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Lung; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 1983 |
Anaphylactic reactions to industrial toxins.
Topics: Air Pollutants, Occupational; Anaphylaxis; Asthma; Dust; Edible Grain; Female; Humans; Male; Mites; Occupational Diseases; Potassium; Potassium Compounds; Skin Tests; Sulfates; Toluene 2,4-Diisocyanate | 1983 |
Antigen-specific stimulation of histamine releasing factors in diisocyanate-induced occupational asthma.
Topics: Allergens; Antibody Specificity; Asthma; Biomarkers; Biomarkers, Tumor; Cells, Cultured; Dose-Response Relationship, Immunologic; Epitopes; Female; Histamine Release; Humans; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Occupational Diseases; Statistics, Nonparametric; Toluene 2,4-Diisocyanate; Tumor Protein, Translationally-Controlled 1 | 1994 |
Cytokines in the airway mucosa of subjects with asthma induced by toluene diisocyanate.
Topics: Adult; Asthma; Biopsy; Bronchi; Cell Adhesion; Cell Adhesion Molecules; Cytokines; E-Selectin; Female; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Leukocytes; Lymphocyte Activation; Male; Mast Cells; Occupational Diseases; Receptors, Interleukin-2; Receptors, Very Late Antigen; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 1995 |
An asthma model developed in the guinea pig by intranasal application of 2,4-toluene diisocyanate.
Topics: Administration, Intranasal; Animals; Asthma; Disease Models, Animal; Guinea Pigs; Histamine Release; Immunoglobulin E; Immunoglobulin G; Lung; Male; Passive Cutaneous Anaphylaxis; Respiration; Toluene 2,4-Diisocyanate | 1993 |
Cellular and mediator profile in bronchoalveolar lavage of guinea pigs after toluene diisocyanate (TDI) exposure.
Topics: Animals; Arachidonic Acid; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Calcimycin; Dose-Response Relationship, Drug; Eosinophils; Female; Guinea Pigs; Inflammation Mediators; Leukocyte Count; Leukotrienes; Prostaglandin D2; Thromboxane B2; Toluene 2,4-Diisocyanate | 1995 |
Airway wall remodeling after cessation of exposure to isocyanates in sensitized asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate | 1995 |
CD8 T-cell clones producing interleukin-5 and interferon-gamma in bronchial mucosa of patients with asthma induced by toluene diisocyanate.
Topics: Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Case-Control Studies; CD8-Positive T-Lymphocytes; Cells, Cultured; Clone Cells; Humans; Immunophenotyping; Interferon-gamma; Interleukin-5; Lymphocyte Activation; Male; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate | 1994 |
Eosinophil cationic protein (ECP), histamine and tryptase in peripheral blood before and during inhalation challenge with toluene diisocyanate (TDI) in sensitized subjects.
Topics: Administration, Inhalation; Adult; Asthma; Blood Proteins; Chymases; Eosinophil Granule Proteins; Female; Histamine; Humans; Male; Middle Aged; Ribonucleases; Serine Endopeptidases; Toluene 2,4-Diisocyanate; Tryptases | 1994 |
Low molecular weight pollutants and asthma: pathogenetic mechanisms and genetic factors.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Immunity, Cellular; Molecular Weight; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate | 1994 |
Predictive value of airways hyperresponsiveness and circulating IgE for identifying types of responses to toluene diisocyanate inhalation challenge.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chi-Square Distribution; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Immunoglobulin G; Male; Methacholine Chloride; Occupational Diseases; Predictive Value of Tests; Reproducibility of Results; Skin Tests; Toluene 2,4-Diisocyanate | 1994 |
Bronchial hyperresponsiveness and toluene diisocyanate. Long-term change in sensitized asthmatic subjects.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate | 1993 |
Toluene diisocyanate induced asthma: outcome according to persistence or cessation of exposure.
Topics: Asthma; Follow-Up Studies; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate | 1993 |
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Eosinophilia; Female; Humans; Isocyanates; Leukocyte Count; Male; Occupational Diseases; Sputum; Toluene 2,4-Diisocyanate | 1994 |
[Airway inflammatory cell dynamics during late asthmatic reactions induced by toluene diisocyanate in guinea pigs. I. Bronchoalveolar lavage study].
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Guinea Pigs; Hypersensitivity, Delayed; Inflammation; Male; Respiratory System; Toluene 2,4-Diisocyanate | 1993 |
[A case of hypersensitivity pneumonitis induced by toluene diisocyanate presenting with transient bronchoconstriction].
Topics: Alveolitis, Extrinsic Allergic; Asthma; Bronchoconstriction; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1993 |
[Airway inflammatory cell dynamics during late asthmatic reactions induced by toluene diisocyanate in guinea pigs. II. Histological study].
Topics: Animals; Asthma; Bronchi; Eosinophils; Guinea Pigs; Hypersensitivity, Delayed; Inflammation; Male; Neutrophils; Toluene 2,4-Diisocyanate | 1993 |
Toluene diisocyanate induced asthma: outcome according to persistence or cessation of exposure.
Topics: Adult; Asthma; Chemical Industry; Follow-Up Studies; Forced Expiratory Volume; Humans; Occupational Diseases; Occupational Exposure; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate; Vital Capacity | 1993 |
A survey of a small group of workers exposed to toluene di-isocyanate.
Topics: Asthma; Chemical Industry; Humans; Occupational Exposure; Radioallergosorbent Test; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate | 1993 |
Mast cells in the airway mucosa and rapid development of occupational asthma induced by toluene diisocyanate.
Topics: Adult; Aged; Asthma; Bronchi; Female; Humans; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate | 1993 |
Response to isocyanates: effect of concentration, duration of exposure, and dose.
Topics: Adult; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Toluene 2,4-Diisocyanate | 1993 |
[Toluene 2,4-diisocyanate induced late asthmatic response and dual asthmatic response in guinea pigs].
Topics: Animals; Asthma; Disease Models, Animal; Guinea Pigs; Hypersensitivity, Delayed; Immunoglobulin E; Immunoglobulin G; Male; Passive Cutaneous Anaphylaxis; Toluene 2,4-Diisocyanate | 1993 |
Bronchial responsiveness to ultrasonic fog in occupational asthma due to toluene diisocyanate.
Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Chloride; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Ultrasonics; Water | 1993 |
Late respiratory response and associated eosinophilic inflammation induced by repeated exposure to toluene diisocyanate in guinea pigs.
Topics: Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Hydrocortisone; Leukocyte Count; Lymphocyte Count; Macrophages; Male; Metyrapone; Neutrophils; Respiration; Time Factors; Toluene 2,4-Diisocyanate | 1996 |
Inflammatory events in the blood and airways of guinea pigs immunized to toluene diisocyanate.
Topics: Animals; Antibodies; Asthma; Blood Cell Count; Bronchi; Eosinophils; Guinea Pigs; Immunization; Immunoglobulin G; Immunohistochemistry; Inflammation; Lung; Male; Mast Cells; Toluene 2,4-Diisocyanate | 1996 |
Association between toluene diisocyanate-induced asthma and DQB1 markers: a possible role for aspartic acid at position 57.
Topics: Adult; Alleles; Aspartic Acid; Asthma; Female; Gene Frequency; Genetic Markers; Haplotypes; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Polymerase Chain Reaction; Toluene 2,4-Diisocyanate | 1996 |
Isocyanate-induced occupational asthma: challenge and immunologic studies.
Topics: Allergens; Asthma; Female; Humans; Immunoglobulin E; Male; Occupational Exposure; Toluene 2,4-Diisocyanate | 1996 |
Toluene diisocyanate-induced in vitro tracheal hyperreactivity in the mouse.
Topics: Adoptive Transfer; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Eosinophil Peroxidase; Eosinophils; Immunoglobulin E; Lung; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Peroxidase; Peroxidases; Time Factors; Toluene 2,4-Diisocyanate; Trachea | 1996 |
Phenyl isocyanate is a potent chemical sensitizer.
Topics: Animals; Antibody Formation; Asthma; Cyanates; Dermatitis, Contact; Ear, External; Immunity, Cellular; Immunoglobulin E; Isocyanates; Mice; Mice, Inbred BALB C; Toluene 2,4-Diisocyanate | 1996 |
Comparison between peak expiratory flow and forced expiratory volume in one second (FEV1) during bronchoconstriction induced by different stimuli.
Topics: Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Exercise Test; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Nebulizers and Vaporizers; Peak Expiratory Flow Rate; Regression Analysis; Sensitivity and Specificity; Toluene 2,4-Diisocyanate; Water | 1997 |
Linking isocyanates and asthma.
Topics: Asthma; Blood Proteins; Carcinogens; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Phenylenediamines; Polymers; Stereoisomerism; Sweden; Toluene 2,4-Diisocyanate | 1997 |
Seroimmunological characteristics of Korean workers exposed to toluene diisocyanate.
Topics: Adult; Asthma; Female; Humans; Immunoglobulin E; Immunoglobulin G; Korea; Male; Middle Aged; Occupational Diseases; Sensitivity and Specificity; Toluene 2,4-Diisocyanate | 1997 |
Prognostic factors for toluene diisocyanate-induced occupational asthma after removal from exposure.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Environmental Exposure; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Longitudinal Studies; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Prognosis; Smoking; Steroids; Toluene 2,4-Diisocyanate | 1997 |
Expression of interleukin (IL)-4 and IL-5 proteins in asthma induced by toluene diisocyanate (TDI).
Topics: Adult; Asthma; Biopsy; Bronchi; Chronic Disease; Eosinophils; Female; Humans; Immunohistochemistry; Interleukin-4; Interleukin-5; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; T-Lymphocytes; Toluene 2,4-Diisocyanate | 1997 |
Immunohistochemical characterization of the cellular infiltrate in airway mucosa of toluene diisocyanate (TDI)-induced asthma: comparison with allergic asthma.
Topics: Adult; Asthma; Bronchi; Eosinophils; Female; Humans; Leukocyte Count; Male; Mast Cells; Middle Aged; Mucous Membrane; Neutrophils; T-Lymphocytes; Toluene 2,4-Diisocyanate | 1998 |
The in vivo effect of isocyanate-induced asthma on basophil histamine release.
Topics: Adult; Aged; Asthma; Basophils; Forced Expiratory Volume; Histamine Release; Humans; Male; Middle Aged; Toluene 2,4-Diisocyanate | 1998 |
Heterogeneity of IgE response to TDI-HSA conjugates by ELISA in toluene diisocyanate (TDI) -induced occupational asthma (OA) patients.
Topics: Antibody Specificity; Asthma; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E; Occupational Diseases; Serum Albumin; Toluene 2,4-Diisocyanate | 1998 |
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma.
Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1 | 1998 |
Nasal response in subjects undergoing challenges by inhaling occupational agents causing asthma through the nose and mouth.
Topics: Administration, Inhalation; Adult; Allergens; Asthma; Female; Flour; Forced Expiratory Volume; Galactans; Humans; Male; Mannans; Middle Aged; Mouth Mucosa; Nasal Mucosa; Nasal Provocation Tests; Occupational Diseases; Occupational Exposure; Plant Gums; Toluene 2,4-Diisocyanate | 1998 |
Cytokine secretion patterns of T cells responding to haptenized-human serum albumin in toluene diisocyanate (TDI)-induced asthma patients.
Topics: Allergens; Asthma; Cell Division; Cells, Cultured; Haptens; Humans; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Serum Albumin; T-Lymphocytes; Toluene 2,4-Diisocyanate | 1998 |
Increase in non-specific bronchial hyperresponsiveness without specific response to isocyanate in isocyanate-induced asthma: a pilot study.
Topics: Adult; Air Pollutants, Occupational; Analysis of Variance; Asthma; Bronchial Hyperreactivity; Female; Humans; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Parasympathomimetics; Pilot Projects; Predictive Value of Tests; Statistics, Nonparametric; Toluene 2,4-Diisocyanate | 1998 |
Specific IgG response to monomeric and polymeric diphenylmethane diisocyanate conjugates in subjects with respiratory reactions to isocyanates.
Topics: Adult; Allergens; Antibody Specificity; Asthma; Cross Reactions; Female; Forced Expiratory Volume; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1999 |
Specific IgG, but not specific IgE, antibodies to toluene diisocyanate-human serum albumin conjugate are associated with toluene diisocyanate bronchoprovocation test results.
Topics: Adult; Antibody Specificity; Asthma; Bronchial Provocation Tests; Female; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Male; Serum Albumin; Toluene 2,4-Diisocyanate | 1999 |
Neutrophil activation following TDI bronchial challenges to the airway secretion from subjects with TDI-induced asthma.
Topics: Adult; Asthma; Bronchi; Bronchoconstrictor Agents; Female; Humans; Interleukin-8; Male; Methacholine Chloride; Middle Aged; Neutrophil Activation; Occupational Diseases; Peroxidase; Sputum; Toluene 2,4-Diisocyanate | 1999 |
Respiratory health surveillance in a toluene di-isocyanate production unit, 1967-97: clinical observations and lung function analyses.
Topics: Asthma; Cohort Studies; Cross-Sectional Studies; Female; Forced Expiratory Volume; Humans; Incidence; Longitudinal Studies; Male; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate; Vital Capacity | 2000 |
Association between HLA genes and susceptibility to toluene diisocyanate-induced asthma.
Topics: Adult; Asthma; Female; Genes, MHC Class II; Genetic Predisposition to Disease; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Male; Occupational Diseases; Toluene 2,4-Diisocyanate | 2000 |
Effect of toluene diisocyanate and its corresponding amines on viability and growth of human lung fibroblasts in culture.
Topics: Asthma; Carcinogens; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cytotoxins; Fibroblasts; Humans; Hydrogen Peroxide; Lung; Occupational Diseases; Oxidants; Phenylenediamines; Tetrazolium Salts; Thiazoles; Toluene 2,4-Diisocyanate | 1999 |
Long-term follow-up of hexamethylene diisocyanate-, diphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma.
Topics: Adult; Air Pollutants; Allergens; Asthma; Cyanates; Female; Follow-Up Studies; Humans; Immunoglobulin E; Isocyanates; Male; Surveys and Questionnaires; Toluene 2,4-Diisocyanate | 2000 |
Isocyanate exposure and occupational asthma: a case-referent study.
Topics: Adolescent; Adult; Allergens; Asthma; Case-Control Studies; Female; Humans; Hypersensitivity, Immediate; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Risk Factors; Smoking; Toluene 2,4-Diisocyanate | 2000 |
Two cases of paraoccupational asthma due to toluene diisocyanate (TDI).
Topics: Adult; Asthma; Female; Humans; Male; Middle Aged; Occupational Diseases; Paint; Polyurethanes; Toluene 2,4-Diisocyanate | 2000 |
Health information in material safety data sheets for a chemical which causes asthma.
Topics: Asthma; Drug Labeling; Humans; Occupational Diseases; Occupational Exposure; Toluene 2,4-Diisocyanate | 2001 |
Diverse profiles of specific IgE response to toluene diisocyanate (TDI)-human serum albumin conjugate in TDI-induced asthma patients.
Topics: Asthma; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin E; Serum Albumin; Toluene 2,4-Diisocyanate | 2001 |
Asthma from diisocyanates is not mediated through a Type IV, patch-test-positive mechanism.
Topics: Adult; Allergens; Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Female; Hand Dermatoses; Humans; Isocyanates; Male; Middle Aged; Paint; Patch Tests; Toluene 2,4-Diisocyanate | 2001 |
Importance of inflammatory and immune components in a mouse model of airway reactivity to toluene diisocyanate (TDI).
Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Disease Models, Animal; Female; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Nude; Toluene 2,4-Diisocyanate | 2001 |
A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Protease Inhibitors; Toluene 2,4-Diisocyanate | 2001 |
Elevated interleukin-4 and interleukin-6 in rats sensitized with toluene diisocyanate.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-4; Interleukin-6; Lung; Lymphocyte Subsets; Lymphocytes; Male; Occupational Diseases; Rats; Rats, Wistar; Spleen; Statistics, Nonparametric; Toluene 2,4-Diisocyanate | 2001 |
Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma.
Topics: Administration, Inhalation; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Migration Inhibition; Cell Movement; Disease Models, Animal; Endothelial Growth Factors; Extravasation of Diagnostic and Therapeutic Materials; Female; Indoles; Inflammation; Leukocyte Count; Lymphokines; Mice; Mice, Inbred BALB C; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Toluene 2,4-Diisocyanate; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Specific immunoglobulin E and immunoglobulin G antibodies to toluene diisocyanate-human serum albumin conjugate: useful markers for predicting long-term prognosis in toluene diisocyanate-induced asthma.
Topics: Asthma; Biomarkers; Bronchial Hyperreactivity; Humans; Immunoglobulin E; Immunoglobulin G; Kinetics; Prognosis; Serum Albumin; Toluene 2,4-Diisocyanate | 2002 |
Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Time Factors; Toluene 2,4-Diisocyanate | 2002 |
Toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Cyanates; Dose-Response Relationship, Drug; Humans; Maximum Allowable Concentration; Occupational Diseases; Toluene 2,4-Diisocyanate | 1978 |
Epidemiology of toluene diisocyanate (TDI)-induced respiratory disease.
Topics: Asthma; Bronchitis; Chemical Industry; Cyanates; Environmental Exposure; Eosinophils; Forced Expiratory Volume; Humans; Leukocyte Count; Lung Diseases, Obstructive; Maximum Allowable Concentration; Occupational Diseases; Respiratory Tract Diseases; Toluene 2,4-Diisocyanate | 1975 |
Occupational type test for the etiological diagnosis of asthma due to toluene di-isocyanate.
Topics: Acetylcholine; Adult; Aerosols; Asthma; Bronchi; Cyanates; Evaluation Studies as Topic; Forced Expiratory Volume; Humans; Male; Methods; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
Bronchial provocation tests in etiologic diagnosis and analysis of asthma.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Aspergillus fumigatus; Asthma; Bronchi; Bronchodilator Agents; Cromolyn Sodium; Dust; Environmental Exposure; Flour; Foreign-Body Reaction; Granuloma; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunoglobulin E; Immunoglobulin G; Occupational Diseases; Piperazines; Platinum; Pulmonary Alveoli; Resins, Plant; Resins, Synthetic; Respiratory Function Tests; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate; Wood | 1975 |
[Asthma caused by di-isocyanate].
Topics: Asthma; Cyanates; Environmental Exposure; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
[Isocyanate poisoning].
Topics: Air Pollutants; Air Pollutants, Occupational; Animals; Asthma; Bronchitis; Cyanates; Humans; Occupational Medicine; Toluene 2,4-Diisocyanate | 1975 |
Asthma due to non-occupational exposure to toluene (tolylene) di-isocyanate.
Topics: Adult; Air Pollutants; Air Pollutants, Occupational; Asthma; Cyanates; Environmental Exposure; Female; Humans; Male; Middle Aged; Time Factors; Toluene 2,4-Diisocyanate; Ventilation | 1976 |
[Asthma and respiratory symptome induced by isocyanates].
Topics: Adult; Asthma; Bronchitis; Cyanates; Environmental Exposure; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1976 |
Occupational asthma caused by low molecular weight chemical agents.
Topics: Anhydrides; Asthma; Humans; Lymphokines; Molecular Weight; Occupational Diseases; Occupational Medicine; Phthalic Acids; Toluene 2,4-Diisocyanate; Tricarboxylic Acids | 1977 |
The in vitro effect of toluene diisocyanate on lymphocyte cyclic adenosine monophosphate production by isoproterenol, prostaglandin, and histamine: a possible mode of action.
Topics: Asthma; Cyanates; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lung; Lymphocytes; Prostaglandins E; Solvents; Toluene 2,4-Diisocyanate | 1977 |
Toluene di-isocyanate (TDI).
Topics: Asthma; Cyanates; Humans; Nasal Polyps; Occupational Diseases; Respiratory System; Toluene 2,4-Diisocyanate; United Kingdom | 1977 |
Recurrent nocturnal asthma due to tolylene di-isocyanate: a case report.
Topics: Adult; Allergens; Asthma; Circadian Rhythm; Cyanates; Humans; Male; Occupational Diseases; Occupations; Recurrence; Toluene 2,4-Diisocyanate | 1978 |
[Bronchial asthma presumably caused by isocyanate in "Yamanaka, Japan-Ware" workers (author's transl)].
Topics: Adult; Asthma; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1978 |
Occupational lung disease.
Topics: Asthma; Berylliosis; Bronchitis; Byssinosis; Carcinoma, Bronchogenic; Environmental Exposure; Humans; Lung Diseases; Lung Neoplasms; Occupational Diseases; Pneumoconiosis; Pulmonary Alveoli; Respiratory Hypersensitivity; Silicosis; Toluene 2,4-Diisocyanate | 1978 |
Toluene di-isocyanate-induced asthma. I. Reactions to TDI, MDI, HDI and histamine.
Topics: Asthma; Benzhydryl Compounds; Cyanates; Hexamethonium Compounds; Histamine; Humans; Male; Toluene 2,4-Diisocyanate | 1979 |
Toluene di-isocyanate-induced asthma. II. Inhalation challenge tests and bronchial reactivity studies.
Topics: Adult; Asthma; Cyanates; Exercise Test; Histamine; Humans; Middle Aged; Respiratory Function Tests; Rhinitis, Allergic, Seasonal; Smoking; Toluene 2,4-Diisocyanate | 1979 |
Patterns of airway reactivity to asthma produced by exposure to toluene di-isocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Airway Resistance; Asthma; Bronchi; Cyanates; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Humans; Maximal Expiratory Flow-Volume Curves; Methacholine Compounds; Occupational Diseases; Ohio; Toluene 2,4-Diisocyanate | 1979 |
Peak flow rate records in the diagnosis of occupational asthma due to isocyanates.
Topics: Asthma; Cyanates; England; Humans; Occupational Diseases; Peak Expiratory Flow Rate; Printing; Time Factors; Toluene 2,4-Diisocyanate | 1979 |
[Diseases caused by diisocyanates. 2. Diisocyanate asthma].
Topics: Asthma; Cyanates; Humans; Immune Complex Diseases; Immunity, Cellular; Immunoglobulin E; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
Occupational asthma: overview and mechanisms.
Topics: Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
Inhalation challenge testing with toluene diisocyanate.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
A proposed standardized method for bronchoprovocation tests in toluene diisocyanate--induced asthma.
Topics: Air Pollutants; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Occupational Diseases; Toluene 2,4-Diisocyanate | 1979 |
[On the pathogenesis of isocyanate-induced asthma].
Topics: Adult; Asthma; Cyanates; Humans; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Respiratory Function Tests; Toluene 2,4-Diisocyanate | 1979 |
Airway mucosal inflammation in occupational asthma induced by toluene diisocyanate.
Topics: Adolescent; Adult; Asthma; Basement Membrane; Bronchi; Bronchoscopy; Eosinophils; Epithelium; Female; Humans; Inflammation; Male; Mast Cells; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate | 1992 |
Effect of cessation of exposure to toluene diisocyanate (TDI) on bronchial mucosa of subjects with TDI-induced asthma.
Topics: Adult; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchoscopy; Female; Humans; Inflammation; Male; Middle Aged; Mucous Membrane; Occupational Diseases; Toluene 2,4-Diisocyanate | 1992 |
Occupational asthma caused by a prepolymer but not the monomer of toluene diisocyanate (TDI).
Topics: Adult; Antibodies; Antibody Specificity; Asthma; Bronchial Provocation Tests; Chronic Disease; Construction Materials; Humans; Male; Middle Aged; Occupational Diseases; Polymers; Spirometry; Structure-Activity Relationship; Time Factors; Toluene 2,4-Diisocyanate | 1992 |
Clinical and immunological evaluation of isocyanate-exposed workers.
Topics: Adult; Asthma; Bronchial Provocation Tests; Humans; Immunoglobulin E; Occupational Diseases; Occupational Exposure; Serum Albumin; Toluene 2,4-Diisocyanate | 1992 |
Abnormal lung function in polyurethane foam producers. Weak relationship to toluene diisocyanate exposures.
Topics: Adult; Asthma; Bronchitis; Construction Materials; Female; Humans; Male; Occupational Diseases; Occupational Exposure; Polyurethanes; Prevalence; Regression Analysis; Respiratory Function Tests; Risk Factors; Smoking; Toluene 2,4-Diisocyanate | 1992 |
Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Isocyanates; Male; Methacholine Chloride; Middle Aged; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate | 1991 |
Toluene diisocyanate-induced asthma: clinical findings and bronchial responsiveness studies in 113 exposed subjects with work-related respiratory symptoms.
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Occupational Diseases; Spirometry; Toluene 2,4-Diisocyanate; Vital Capacity | 1991 |
Late asthmatic reactions, airway inflammation and chronic asthma in toluene-diisocyanate-sensitized subjects.
Topics: Asthma; Bronchi; Eosinophils; Humans; Immunization; Inflammation; Lung; Occupational Diseases; Prognosis; Toluene 2,4-Diisocyanate | 1991 |
Allergologic evaluation for workers exposed to toluene diisocyanate.
Topics: Adult; Asthma; China; Cross-Sectional Studies; Dermatitis, Contact; Female; Humans; Male; Occupational Diseases; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate | 1991 |
Detoxification of an aliphatic amine by N-acetylation: experimental and clinical studies.
Topics: Acetylation; alpha 1-Antitrypsin; Asthma; Diamines; Female; Heterozygote; Homozygote; Humans; Inactivation, Metabolic; Male; Phenotype; Polymorphism, Genetic; Toluene 2,4-Diisocyanate | 1991 |
[An experimental etiological study of toluene diisocyanate (TDI) induced occupational asthma].
Topics: Animals; Asthma; Disease Models, Animal; Guinea Pigs; Immunoglobulin E; Occupational Diseases; Passive Cutaneous Anaphylaxis; Toluene 2,4-Diisocyanate | 1991 |
Increase in numbers of CD8 positive lymphocytes and eosinophils in peripheral blood of subjects with late asthmatic reactions induced by toluene diisocyanate.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Asthma; CD8 Antigens; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Lung; Male; Middle Aged; Occupational Diseases; Occupational Exposure; T-Lymphocytes, Regulatory; Toluene 2,4-Diisocyanate | 1991 |
Airway inflammation during late asthmatic reactions induced by toluene diisocyanate.
Topics: Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Humans; Inflammation; Toluene 2,4-Diisocyanate | 1991 |
Significant changes of bronchial responsiveness to methacholine after early asthmatic reaction to toluene diisocyanate (TDI) in a TDI-sensitive asthmatic worker.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Humans; Male; Methacholine Chloride; Occupational Diseases; Skin Tests; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Persistence of toluene diisocyanate-induced asthma despite negligible workplace exposures.
Topics: Asthma; Cyanates; Forced Expiratory Volume; Humans; Longitudinal Studies; Occupational Diseases; Spirometry; Toluene 2,4-Diisocyanate; Vital Capacity | 1990 |
Neutrophil chemotactic activity in toluene diisocyanate (TDI)-induced asthma.
Topics: Animals; Asthma; Basophils; Bronchial Provocation Tests; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Chromatography, Gel; Cyanates; Forced Expiratory Volume; Humans; Mast Cells; Methacholine Chloride; Methacholine Compounds; Mites; Molecular Weight; Neutrophils; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Persistent reactive airway dysfunction syndrome after exposure to toluene diisocyanate.
Topics: Accidents, Traffic; Adult; Asthma; Cyanates; Follow-Up Studies; Humans; Lung; Male; Middle Aged; Occupational Diseases; Prednisolone; Social Control, Formal; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Airway inflammation and late asthmatic reactions.
Topics: Asthma; Bronchi; Cyanates; Humans; Pulmonary Ventilation; Time Factors; Toluene 2,4-Diisocyanate | 1990 |
Leukotriene B4 and late asthmatic reactions induced by toluene diisocyanate.
Topics: Adult; Asthma; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cyanates; Female; Humans; Leukocyte Count; Leukotriene B4; Male; Neutrophils; Toluene 2,4-Diisocyanate | 1990 |
Bronchoalveolar lavage and morphology of the airways after cessation of exposure in asthmatic subjects sensitized to toluene diisocyanate.
Topics: Adult; Asthma; Biopsy; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Count; Cyanates; Female; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1990 |
Occupational asthma due to isocyanates in Singapore.
Topics: Adolescent; Adult; Aged; Asthma; Cyanates; Female; Humans; Infant; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1990 |
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers.
Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate | 1989 |
[Bronchial asthma caused by isocyanate in the internal/external environment].
Topics: Asthma; Cyanates; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1989 |
[Occupational toluene diisocyanate (TDI) asthma--inhalation challenge test and TDI-HSA (human serum albumin) skin test and detection of specific IgE].
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Male; Occupational Diseases; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate | 1989 |
Importance of airway inflammation for late asthmatic reactions induced by toluene diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Cyanates; Humans; Inflammation; Male; Methacholine Chloride; Methacholine Compounds; Respiratory System; Time Factors; Toluene 2,4-Diisocyanate | 1987 |
Atropine does not inhibit late asthmatic responses induced by toluene-diisocyanate in sensitized subjects.
Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Atropine; Carbachol; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1987 |
Occupational asthma due to toluene diisocyanate among velcro-like tape manufacturers.
Topics: Adhesives; Air Pollutants, Occupational; Asthma; Cyanates; Female; Humans; Male; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Ventilation | 1988 |
Increases in airway responsiveness following acute exposure to respiratory irritants. Reactive airway dysfunction syndrome or occupational asthma?
Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Bronchial Provocation Tests; Female; Humans; Hydrochloric Acid; Male; Middle Aged; Occupational Diseases; Respiratory Tract Diseases; Sulfuric Acids; Tetrachloroethylene; Toluene 2,4-Diisocyanate | 1988 |
Cross-reaction between aromatic isocyanates (TDI and MDI): a specific bronchial provocation test study.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cross Reactions; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate | 1988 |
Recurrent asthma induced by toluene diisocyanate.
Topics: Adult; Asthma; Chemical Industry; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Recurrence; Toluene 2,4-Diisocyanate | 1988 |
Persistent asthma due to isocyanates. A follow-up study of subjects with occupational asthma due to toluene diisocyanate (TDI).
Topics: Asthma; Bronchial Provocation Tests; Chronic Disease; Cyanates; Environmental Exposure; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Toluene 2,4-Diisocyanate | 1988 |
Fatal asthma in a subject sensitized to toluene diisocyanate.
Topics: Adult; Asthma; Bronchial Spasm; Cyanates; Environmental Exposure; Humans; Lung; Male; Paint; Polyurethanes; Toluene 2,4-Diisocyanate | 1988 |
Increased neutrophil leukocyte chemotaxis induced by release of a serum factor in toluene-diisocyanate (TDI) asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Chemotactic Factors; Chemotaxis, Leukocyte; Cyanates; Female; Humans; Interleukin-8; Male; Neutrophils; Occupational Diseases; Toluene 2,4-Diisocyanate | 1988 |
Experiences of specific IgE in asthma due to diisocyanates.
Topics: Antibody Formation; Antibody Specificity; Antigen-Antibody Complex; Asthma; Bronchial Provocation Tests; Cyanates; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Isocyanates; Radioallergosorbent Test; Skin Tests; Toluene 2,4-Diisocyanate | 1988 |
TDI-induced oculorhinitis and bronchial asthma.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Endophthalmitis; Humans; Immunoglobulin E; Male; Middle Aged; Occupational Diseases; Paint; Rhinitis; Toluene 2,4-Diisocyanate | 1985 |
Time course of the increase in airway responsiveness associated with late asthmatic reactions to toluene diisocyanate in sensitized subjects.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Cyanates; Female; Humans; Hypersensitivity, Delayed; Male; Toluene 2,4-Diisocyanate | 1985 |
Combined asthma and alveolitis due to diphenylmethane diisocyanate (MDI) with demonstration of no crossed respiratory reactivity to toluene diisocyanate (TDI).
Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Neutrophils; Therapeutic Irrigation; Toluene 2,4-Diisocyanate | 1985 |
Occupational asthma in a steel coating plant.
Topics: Adult; Asthma; Cross-Sectional Studies; Cyanates; Disease Outbreaks; England; Female; Follow-Up Studies; Humans; Male; Metallurgy; Middle Aged; Occupational Diseases; Peak Expiratory Flow Rate; Respiratory Function Tests; Skin Tests; Toluene 2,4-Diisocyanate | 1985 |
[Toluene diisocyanate induced asthma].
Topics: Adult; Asthma; Cyanates; Female; Humans; Immunoglobulin E; Male; Middle Aged; Respiratory Hypersensitivity; Toluene 2,4-Diisocyanate | 1985 |
Prednisone inhibits late asthmatic reactions and the associated increase in airway responsiveness induced by toluene-diisocyanate in sensitized subjects.
Topics: Adult; Asthma; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Prednisone; Respiratory System; Toluene 2,4-Diisocyanate | 1985 |
Cholinergic muscarinic receptor in the nasal mucosa of guinea pigs with bronchial asthma with and without hypersensitive nasal symptoms.
Topics: alpha-Amylases; Animals; Asthma; Binding Sites; Guinea Pigs; Immunoglobulin E; Male; Nasal Mucosa; Receptors, Cholinergic; Receptors, Muscarinic; Rhinitis; Toluene 2,4-Diisocyanate | 1985 |
Toluene diisocyanate-induced asthma without airway hyperresponsiveness.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate | 1986 |
Persistent airways disease caused by toluene diisocyanate.
Topics: Asthma; Bronchial Provocation Tests; Cyanates; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate | 1986 |
Specific bronchial reactivity to toluene diisocyanate: relationship with baseline clinical findings.
Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Toluene 2,4-Diisocyanate | 1986 |
Chronic asthma due to toluene diisocyanate.
Topics: Adult; Asthma; Chronic Disease; Cyanates; Forced Expiratory Volume; Humans; Middle Aged; Occupational Diseases; Prognosis; Retrospective Studies; Time Factors; Toluene 2,4-Diisocyanate; Vital Capacity | 1986 |
[Health hazards in workers of small scale polyurethane production factory].
Topics: Adolescent; Adult; Aged; Asthma; Chemical Industry; Cyanates; Female; Humans; Isocyanates; Male; Middle Aged; Morbidity; Occupational Diseases; Polyurethanes; Toluene 2,4-Diisocyanate | 1986 |
Specific bronchial reactivity to toluene diisocyanate: dose-response relationship.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Differential Threshold; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Methacholine Chloride; Methacholine Compounds; Toluene 2,4-Diisocyanate | 1986 |
Late, but not early, asthmatic reactions induced by toluene-diisocyanate are associated with increased airway responsiveness to methacholine.
Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Occupational Diseases; Time Factors; Toluene 2,4-Diisocyanate | 1986 |
[Chemotaxic activity of granulocytes in toluene diisocyanate-induced asthma].
Topics: Adult; Asthma; Chemotaxis, Leukocyte; Cyanates; Female; Humans; Male; Neutrophils; Toluene 2,4-Diisocyanate | 1986 |
[A case report on death due to an asthmatic attack observed in a guinea pig with TDI-induced asthma].
Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Guinea Pigs; Lung; Male; Nasal Mucosa; Toluene 2,4-Diisocyanate | 1986 |
Bronchoalveolar neutrophilia during late asthmatic reactions induced by toluene diisocyanate.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyanates; Dose-Response Relationship, Drug; Eosinophils; Forced Expiratory Volume; Humans; Leukocyte Count; Methacholine Chloride; Methacholine Compounds; Neutrophils; Pulmonary Alveoli; Therapeutic Irrigation; Time Factors; Toluene 2,4-Diisocyanate | 1987 |
The prevalence of asthma among inhabitants in the vicinity of a polyurethane factory in Finland.
Topics: Adolescent; Adult; Air Pollutants, Occupational; Asthma; Child; Environmental Exposure; Finland; Humans; Isomerism; Middle Aged; Polyurethanes; Sulfur Dioxide; Toluene 2,4-Diisocyanate | 1987 |
Toluene diisocyanate respiratory reactions. I. Reassessment of the problem.
Topics: Adult; Asthma; Cyanates; Humans; Immunoglobulins; Isomerism; Middle Aged; Occupational Diseases; Respiration; Toluene 2,4-Diisocyanate | 1987 |