tolterodine-tartrate and Spasm

To evaluate the efficacy of tolterodine on bladder spasm caused by the indwelling catheter after prostate operation.. Eighty-two patients with bladder spasm caused by the indwelling catheter after prostate operation received tolterodine (2 mg twice daily), until 24 hours before the removal of the catheter.. After 24 hours of treatment, bladder spasm was alleviated totally in 21 patients (25.6%), partially in 45 (54.9%), and unrelieved in 16 (19.5%). After 72 hours of treatment, bladder spasm was alleviated totally in 45 patients (54.9%), partially in 30 (36.6%), and unrelieved in 7 (8.5%). No severe adverse events occurred during the treatment.. The tolterodine therapy for patients with bladder spasm caused by the indwelling catheter after prostate operations is rapid, effective, persistent and safe.

Topics: Aged; Aged, 80 and over; Benzhydryl Compounds; Catheters, Indwelling; Cresols; Humans; Male; Middle Aged; Phenylpropanolamine; Spasm; Tolterodine Tartrate; Transurethral Resection of Prostate; Urinary Bladder Diseases; Urinary Catheterization