Page last updated: 2024-08-23

tolrestat and Disease Models, Animal

tolrestat has been researched along with Disease Models, Animal in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Behera, P; Sahoo, PK1
Lou, MF; Xu, GT; York, B; Zigler, S1
Epstein, M; Forster, HG; Hohman, TC; ter Wee, PM1
Hohman, TC; Kinoshita, JH; Laver, N; Nagata, M; Robison, WG1
Kinoshita, JH; Laver, N; Nagata, M; Robison, WG; Tillis, TN1
Kador, PF; Kinoshita, JH; Sharpless, NE1

Reviews

1 review(s) available for tolrestat and Disease Models, Animal

ArticleYear
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution

1985

Other Studies

5 other study(ies) available for tolrestat and Disease Models, Animal

ArticleYear
Synthesis and biological evaluation of [1,2,4]triazino[4,3-a] benzimidazole acetic acid derivatives as selective aldose reductase inhibitors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Acetic Acid; Aldehyde Reductase; Animals; Benzimidazoles; Cataract; Disease Models, Animal; Enzyme Inhibitors; Galactosemias; Inhibitory Concentration 50; Molecular Structure; Naphthalenes; Ophthalmic Solutions; Rats

2010
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
    Current eye research, 1996, Volume: 15, Issue:4

    Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Spiro Compounds

1996
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat.
    Diabetologia, 1996, Volume: 39, Issue:8

    Topics: Aldehyde Reductase; Angiotensin II; Animals; Arterioles; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Galactitol; Galactose; Image Processing, Computer-Assisted; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Naphthalenes; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents

1996
Diabetic-like retinopathy in rats prevented with an aldose reductase inhibitor.
    Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:11

    Topics: Aldehyde Reductase; Animals; Basement Membrane; Blood Glucose; Diabetic Retinopathy; Disease Models, Animal; Female; Galactose; Naphthalenes; Polymers; Random Allocation; Rats; Rats, Inbred Strains; Retinal Vessels; Sugar Alcohol Dehydrogenases

1989
Aldose reductase and pericyte-endothelial cell contacts in retina and optic nerve.
    Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:11

    Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Diabetic Retinopathy; Disease Models, Animal; Endothelium, Vascular; Female; Galactose; Intercellular Junctions; Naphthalenes; Optic Nerve; Rats; Rats, Inbred Strains; Retina; Retinal Vessels; Sugar Alcohol Dehydrogenases

1989