tolrestat has been researched along with Diabetic Glomerulosclerosis in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomlinson, DR | 1 |
| D'Onofrio, F; De Cicco, A; Marrazzo, G; Passariello, N; Peluso, A; Pisano, MC; Sepe, J; Sgambato, S; Tesauro, P | 1 |
| Epstein, M; Forster, HG; Hohman, TC; ter Wee, PM | 1 |
| Donnelly, SM; Huang, JT; Whiteside, CI; Zhou, XP | 1 |
| Cameron, NE; Cotter, MA; Hohman, TC | 1 |
| Azal, O; Baydar, A; Cakir, B; Corakçi, A; Güler, S; Kutlu, M; Yönem, A | 1 |
| Hotta, N; Sakamoto, N | 1 |
| Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
3 review(s) available for tolrestat and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Aldose reductase inhibitors and the complications of diabetes mellitus.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Humans; Kidney; Naphthalenes; Rats | 1993 |
[Clinical application of aldose reductase inhibitors--prevention and therapy of diabetic complications].
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Humans; Imidazoles; Imidazolidines; L-Iditol 2-Dehydrogenase; Naphthalenes; Phthalazines; Sugar Alcohol Dehydrogenases | 1987 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
1 trial(s) available for tolrestat and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Effect of aldose reductase inhibitor (tolrestat) on urinary albumin excretion rate and glomerular filtration rate in IDDM subjects with nephropathy.
Topics: Adult; Albuminuria; Aldehyde Reductase; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Naphthalenes; Regional Blood Flow; Time Factors | 1993 |
4 other study(ies) available for tolrestat and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat.
Topics: Aldehyde Reductase; Angiotensin II; Animals; Arterioles; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Galactitol; Galactose; Image Processing, Computer-Assisted; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Naphthalenes; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1996 |
Prevention of early glomerulopathy with tolrestat in the streptozotocin-induced diabetic rat.
Topics: Ampholyte Mixtures; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney Glomerulus; Male; Naphthalenes; Polymers; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1996 |
Correction of nerve conduction and endoneurial blood flow deficits by the aldose reductase inhibitor, tolrestat, in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Male; Naphthalenes; Neural Conduction; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve | 1998 |
Effects of aminoguanidine and tolrestat on the development of ocular and renal structural changes in experimental diabetic rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Cataract; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diabetic Retinopathy; Diuresis; Enzyme Inhibitors; Guanidines; Kidney; Male; Naphthalenes; Nitric Oxide Synthase; Organ Size; Rats; Rats, Sprague-Dawley; Reference Values | 2002 |