tolrestat has been researched along with Diabetes Mellitus, Type 2 in 12 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 12 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tjon-A-Tsien, AM; van Gerven, JM | 1 |
Balsano, F; Bravi, C; De Mattia, G; Ghiselli, A; Iuliano, L; Laurenti, O | 1 |
van Gerven, JM | 1 |
Ceriello, A; Cozzolino, D; De Rosa, N; Giugliano, D; Marfella, R; Quatraro, A; Salvatore, T; Torella, R | 1 |
De Vincentis, N; Fabiani, F; Staffilano, A | 1 |
Carta, Q; Dani, F; De Mattei, M; Monge, L; Sciarretta, A | 1 |
Carinci, F; Ferris, F; Graepel, JG; Hohman, TC; Lachin, JM; Nicolucci, A | 1 |
Feman, SS; Leonard-Martin, TC; Redman, JR | 1 |
Ihm, SH; Park, CJ; Park, SW; Yoo, HJ | 1 |
Basili, S; Bravi, MC; Cassone-Faldetta, M; De Mattia, G; Ferri, C; Laurenti, O; Pietrangeli, P | 1 |
Brooks, BA; Fisher, EJ; McAuliffe, AV; Molyneaux, LM; Yue, DK | 1 |
Boulton, AJ; Comstock, J; Levin, S | 1 |
2 review(s) available for tolrestat and Diabetes Mellitus, Type 2
Article | Year |
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The efficacy of aldose reductase inhibitors in the management of diabetic complications. Comparison with intensive insulin treatment and pancreatic transplantation.
Topics: Adult; Aged; Aldehyde Reductase; Cross-Sectional Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Imidazoles; Imidazolidines; Insulin; Islets of Langerhans Transplantation; Middle Aged; Naphthalenes; Pancreas Transplantation; Treatment Outcome | 1995 |
The efficacy of tolrestat in the treatment of diabetic peripheral neuropathy. A meta-analysis of individual patient data.
Topics: Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme Inhibitors; Female; Humans; Male; Median Nerve; Middle Aged; Naphthalenes; Neural Conduction; Peroneal Nerve; Randomized Controlled Trials as Topic; Tibial Nerve; Treatment Outcome; Ulnar Nerve | 1996 |
9 trial(s) available for tolrestat and Diabetes Mellitus, Type 2
Article | Year |
---|---|
Further clinical studies with an aldose reductase inhibitor in diabetic neuropathy.
Topics: Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Evoked Potentials, Somatosensory; Female; Humans; Male; Middle Aged; Naphthalenes; Neural Conduction | 1993 |
Tolrestat for mild diabetic neuropathy. A 52-week, randomized, placebo-controlled trial.
Topics: Aldehyde Reductase; Autonomic Nervous System Diseases; Blood Pressure; Cardiovascular System; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Naphthalenes; Peripheral Nerves; Reflex; Sensation; Single-Blind Method | 1993 |
Effect of Tolrestat on oesophageal transit time and cholecystic motility in type 2 diabetic patients with asymptomatic diabetic neuropathy.
Topics: Aged; Aldehyde Reductase; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme Inhibitors; Esophagus; Female; Follow-Up Studies; Gallbladder; Gastrointestinal Transit; Humans; Male; Middle Aged; Naphthalenes; Statistics as Topic; Time Factors | 1995 |
Effect of treatment with an aldose-reductase inhibitor on symptomatic carpal tunnel syndrome in type 2 diabetes.
Topics: Aldehyde Reductase; Carpal Tunnel Syndrome; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Male; Median Nerve; Middle Aged; Motor Neurons; Naphthalenes; Neural Conduction; Neurons, Afferent; Time Factors; Ulnar Nerve | 1995 |
The Vanderbilt Classification System in the evaluation of diabetic retinopathy patients treated with Alredase.
Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Naphthalenes; Observer Variation; Prospective Studies; Reproducibility of Results; Tennessee | 1996 |
Effect of tolrestat, an aldose reductase inhibitor, on neutrophil respiratory burst activity in diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Naphthalenes; Neutrophils; Reference Values; Regression Analysis; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Polyol pathway activation and glutathione redox status in non-insulin-dependent diabetic patients.
Topics: Adult; Aged; Aldehyde Reductase; Diabetes Mellitus, Type 2; Double-Blind Method; Enzyme Inhibitors; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Humans; Male; Middle Aged; NADP; Naphthalenes; Oxidation-Reduction; Reference Values | 1997 |
Administration of ascorbic acid and an aldose reductase inhibitor (tolrestat) in diabetes: effect on urinary albumin excretion.
Topics: Administration, Oral; Adult; Aged; Albuminuria; Aldehyde Reductase; Ascorbic Acid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Glycosaminoglycans; Humans; Male; Middle Aged; Naphthalenes; Placebos; Proteoglycans; Time Factors | 1998 |
A multicentre trial of the aldose-reductase inhibitor, tolrestat, in patients with symptomatic diabetic neuropathy.
Topics: Aldehyde Reductase; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Motor Neurons; Multicenter Studies as Topic; Naphthalenes; Neural Conduction; Pain; Random Allocation; Spinal Nerves; Sugar Alcohol Dehydrogenases | 1990 |
1 other study(ies) available for tolrestat and Diabetes Mellitus, Type 2
Article | Year |
---|---|
Effect of aldose reductase inhibition on glutathione redox status in erythrocytes of diabetic patients.
Topics: Aged; Aldehyde Reductase; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Erythrocytes; Female; Glutathione; Humans; Male; Middle Aged; NADP; Naphthalenes; Oxidation-Reduction | 1994 |