tolrestat has been researched along with Diabetes Mellitus, Type 1 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 10 (90.91) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cayen, MN; Dubuc, J; Dvornik, D; Hicks, DR; Kraml, M; Ryder, S | 1 |
| van Gerven, JM | 1 |
| D'Onofrio, F; De Cicco, A; Marrazzo, G; Passariello, N; Peluso, A; Pisano, MC; Sepe, J; Sgambato, S; Tesauro, P | 1 |
| Chiang, ST; Cohen, AF; Jusko, WJ; Kroon, R; Lemkes, HH; van Griensven, JM; Verhorst, CJ | 1 |
| Coco, MP; Daniele, E | 1 |
| Ziegler, D | 1 |
| Carinci, F; Ferris, F; Graepel, JG; Hohman, TC; Lachin, JM; Nicolucci, A | 1 |
| Feman, SS; Leonard-Martin, TC; Redman, JR | 1 |
| Ihm, SH; Park, CJ; Park, SW; Yoo, HJ | 1 |
| Brooks, BA; Fisher, EJ; McAuliffe, AV; Molyneaux, LM; Yue, DK | 1 |
| Boulton, AJ; Comstock, J; Levin, S | 1 |
3 review(s) available for tolrestat and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
[Tolrestat in the therapy of diabetic peripheral neuropathy: is this drug really useful?].
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hyperglycemia; Male; Middle Aged; Naphthalenes | 1995 |
Diagnosis and management of diabetic peripheral neuropathy.
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Electrodiagnosis; Enzyme Inhibitors; Humans; Naphthalenes; Pain; Prevalence | 1996 |
The efficacy of tolrestat in the treatment of diabetic peripheral neuropathy. A meta-analysis of individual patient data.
Topics: Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme Inhibitors; Female; Humans; Male; Median Nerve; Middle Aged; Naphthalenes; Neural Conduction; Peroneal Nerve; Randomized Controlled Trials as Topic; Tibial Nerve; Treatment Outcome; Ulnar Nerve | 1996 |
8 trial(s) available for tolrestat and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Further clinical studies with an aldose reductase inhibitor in diabetic neuropathy.
Topics: Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Evoked Potentials, Somatosensory; Female; Humans; Male; Middle Aged; Naphthalenes; Neural Conduction | 1993 |
Effect of aldose reductase inhibitor (tolrestat) on urinary albumin excretion rate and glomerular filtration rate in IDDM subjects with nephropathy.
Topics: Adult; Albuminuria; Aldehyde Reductase; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Naphthalenes; Regional Blood Flow; Time Factors | 1993 |
Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.
Topics: Adult; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Erythrocytes; Half-Life; Humans; Male; Matched-Pair Analysis; Naphthalenes; Sorbitol | 1995 |
[Tolrestat in the therapy of diabetic peripheral neuropathy: is this drug really useful?].
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hyperglycemia; Male; Middle Aged; Naphthalenes | 1995 |
The Vanderbilt Classification System in the evaluation of diabetic retinopathy patients treated with Alredase.
Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Double-Blind Method; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Naphthalenes; Observer Variation; Prospective Studies; Reproducibility of Results; Tennessee | 1996 |
Effect of tolrestat, an aldose reductase inhibitor, on neutrophil respiratory burst activity in diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Naphthalenes; Neutrophils; Reference Values; Regression Analysis; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Administration of ascorbic acid and an aldose reductase inhibitor (tolrestat) in diabetes: effect on urinary albumin excretion.
Topics: Administration, Oral; Adult; Aged; Albuminuria; Aldehyde Reductase; Ascorbic Acid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Glycosaminoglycans; Humans; Male; Middle Aged; Naphthalenes; Placebos; Proteoglycans; Time Factors | 1998 |
A multicentre trial of the aldose-reductase inhibitor, tolrestat, in patients with symptomatic diabetic neuropathy.
Topics: Aldehyde Reductase; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Motor Neurons; Multicenter Studies as Topic; Naphthalenes; Neural Conduction; Pain; Random Allocation; Spinal Nerves; Sugar Alcohol Dehydrogenases | 1990 |
1 other study(ies) available for tolrestat and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Tolrestat kinetics.
Topics: Absorption; Adult; Biological Availability; Blood Proteins; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Humans; Kinetics; Male; Naphthalenes; Protein Binding | 1984 |