tolrestat has been researched along with Ache in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calcutt, NA; Malmberg, AB; Yaksh, TL; Yamamoto, T | 1 |
| Ziegler, D | 1 |
| Boulton, AJ; Comstock, J; Levin, S | 1 |
1 review(s) available for tolrestat and Ache
| Article | Year |
|---|---|
Diagnosis and management of diabetic peripheral neuropathy.
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Electrodiagnosis; Enzyme Inhibitors; Humans; Naphthalenes; Pain; Prevalence | 1996 |
1 trial(s) available for tolrestat and Ache
| Article | Year |
|---|---|
A multicentre trial of the aldose-reductase inhibitor, tolrestat, in patients with symptomatic diabetic neuropathy.
Topics: Aldehyde Reductase; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Motor Neurons; Multicenter Studies as Topic; Naphthalenes; Neural Conduction; Pain; Random Allocation; Spinal Nerves; Sugar Alcohol Dehydrogenases | 1990 |
1 other study(ies) available for tolrestat and Ache
| Article | Year |
|---|---|
Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats.
Topics: Aldehyde Reductase; Animals; Behavior, Animal; Body Weight; Diabetes Mellitus, Experimental; Female; Formaldehyde; Galactose; Hyperalgesia; Hyperglycemia; Naphthalenes; Neural Pathways; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sorbitol | 1994 |