tolperisone has been researched along with Stroke in 9 studies
Tolperisone: A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1211)
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the efficacy and safety of tolperisone--a centrally acting muscle relaxant with membrane stabilizing activity--in the treatment of stroke-related spasticity." | 9.12 | [A randomized, double blind, placebo-controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke]. ( Hanasen, C; Horvath, F; Koytchev, R; Kuhn, K; Pongratz, D; Ramm, S; Stamenova, P, 2006) |
| "To study the efficacy and safety of tolperisone - a centrally acting muscle relaxant with membrane stabilizing activity - in the treatment of stroke-related spasticity." | 9.11 | A randomized, double-blind, placebo-controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke. ( Hansen, C; Horvath, F; Koytchev, R; Kuhn, K; Pongratz, D; Ramm, S; Stamenova, P, 2005) |
| "To study the efficacy and safety of tolperisone--a centrally acting muscle relaxant with membrane stabilizing activity--in the treatment of stroke-related spasticity." | 5.12 | [A randomized, double blind, placebo-controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke]. ( Hanasen, C; Horvath, F; Koytchev, R; Kuhn, K; Pongratz, D; Ramm, S; Stamenova, P, 2006) |
| "To study the efficacy and safety of tolperisone - a centrally acting muscle relaxant with membrane stabilizing activity - in the treatment of stroke-related spasticity." | 5.11 | A randomized, double-blind, placebo-controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke. ( Hansen, C; Horvath, F; Koytchev, R; Kuhn, K; Pongratz, D; Ramm, S; Stamenova, P, 2005) |
| " Adverse events in the mydocalm group have been identified more rarely than in the control group." | 2.78 | [Evaluation of efficacy and safety of mydocalm in the early rehabilitation of stroke]. ( Kovalchuk, VV, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovalchuk, VV | 1 |
| Lipták, J | 2 |
| Lindsay, C | 1 |
| Kouzouna, A | 1 |
| Simcox, C | 1 |
| Pandyan, AD | 1 |
| Agarwal, S | 1 |
| Patel, T | 1 |
| Shah, N | 1 |
| Patel, BM | 1 |
| Stamenova, P | 2 |
| Koytchev, R | 2 |
| Kuhn, K | 2 |
| Hansen, C | 1 |
| Horvath, F | 2 |
| Ramm, S | 2 |
| Pongratz, D | 2 |
| Hanasen, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Neuromuscular Electrical Stimulation on Walking Ability and Quality of Life in Individuals With Chronic Stroke[NCT04673045] | 40 participants (Anticipated) | Interventional | 2021-02-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tolperisone and Stroke
| Article | Year |
|---|---|
Pharmacological interventions other than botulinum toxin for spasticity after stroke.
Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle S | 2016 |
5 trials available for tolperisone and Stroke
| Article | Year |
|---|---|
[Evaluation of efficacy and safety of mydocalm in the early rehabilitation of stroke].
Topics: Adult; Case-Control Studies; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle To | 2013 |
[Effectiveness and safety of tolperisone in spasticity following cerebral stroke: randomized, double-blind, placebo-controlled trial].
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Musc | 2013 |
Comparative study of therapeutic response to baclofen vs tolperisone in spasticity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Baclofen; Cerebral Palsy; Child; Child, Preschool; Femal | 2017 |
A randomized, double-blind, placebo-controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke.
Topics: Aged; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; | 2005 |
[A randomized, double blind, placebo-controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke].
Topics: Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Human | 2006 |
3 other studies available for tolperisone and Stroke
| Article | Year |
|---|---|
[Comparative effectiveness of different muscle relaxants in the rehabilitation of post-stroke patients with spasticity].
Topics: Aged; Baclofen; Clonidine; Comparative Effectiveness Research; Dantrolene; Female; Humans; Male; Mus | 2013 |
[To make easier everyday life of stroke patients. Muscle relaxants diminish spasms].
Topics: Double-Blind Method; Humans; Muscle Relaxants, Central; Muscle Spasticity; Placebos; Randomized Cont | 2003 |
[Spastic syndrome. More mobile again after stroke].
Topics: Hemiplegia; Humans; Muscle Relaxants, Central; Muscle Spasticity; Stroke; Tolperisone | 2001 |