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tolperisone and Pain

tolperisone has been researched along with Pain in 12 studies

Tolperisone: A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1211)

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"To generate real world clinical data on efficacy and tolerability of tolperisone 150 mg in painful muscle spasms in Indian population."9.15A phase IV observational multi-centre, open-label study on efficacy and safety of tolperisone 150 mg in patients with painful muscle spasm associated with degenerative or inflammatory diseases of the musculoskeletal system. ( Keny, S; Prabhoo, R; Prabhoo, T; Rana, R; Singh, A, 2011)
"Four patients with anaphylaxis attributed to the intake of the centrally acting muscle relaxant tolperisone hydrochloride (Mydocalm) were observed at the Emergency Department of the Geneva University Hospital between November 2001 and March 2003."7.72Anaphylactic reactions to tolperisone (Mydocalm). ( Hauser, C; Ribi, C; Vermeulen, C, 2003)
"To generate real world clinical data on efficacy and tolerability of tolperisone 150 mg in painful muscle spasms in Indian population."5.15A phase IV observational multi-centre, open-label study on efficacy and safety of tolperisone 150 mg in patients with painful muscle spasm associated with degenerative or inflammatory diseases of the musculoskeletal system. ( Keny, S; Prabhoo, R; Prabhoo, T; Rana, R; Singh, A, 2011)
"The role of tolperisone hydrochloride, a centrally acting muscle relaxant in relieving painful muscle spasm is recently being discussed."5.10Prophylactic tolperisone for post-exercise muscle soreness causes reduced isometric force--a double-blind randomized crossover control study. ( Arendt-Nielsen, L; Bajaj, P; Madeleine, P; Svensson, P, 2003)
"A randomised, double-blind, placebo-controlled three-way cross-over study was performed to investigate the effect of two muscle relaxants (tolperisone hydrochloride and pridinol mesilate) on experimental jaw-muscle pain and jaw-stretch reflexes."5.10Effect of muscle relaxants on experimental jaw-muscle pain and jaw-stretch reflexes: a double-blind and placebo-controlled trial. ( Arendt-Nielsen, L; Svensson, P; Wang, K, 2003)
"Four patients with anaphylaxis attributed to the intake of the centrally acting muscle relaxant tolperisone hydrochloride (Mydocalm) were observed at the Emergency Department of the Geneva University Hospital between November 2001 and March 2003."3.72Anaphylactic reactions to tolperisone (Mydocalm). ( Hauser, C; Ribi, C; Vermeulen, C, 2003)
"The high efficacy of mydocalm in the treatment of pain syndromes with the muscle spasm has been demonstrated."2.80[The results of the multicenter pharmaco-epidemiological observational project on the use of mydocalm in the treatment of pain syndromes with the muscle spasm]. ( Baliazin, VA; Barantsevich, ER; Belova, AN; Bogdanov, EI; Danilenko, OA; Gafurov, BG; Galanov, DV; Guekht, AB; Guseinov, SG; Khabirov, FA; Lebedeva, AV; Miakotnykh, VS; Mishchenko, TS; Musaev, SK; Prokopenko, SV; Shprakh, VV; Shyralieva, RK; Skoromets, AA; Spirin, NN; Toktomushev, CT; Volkova, LI, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's9 (75.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Skoromets, AA1
Guekht, AB1
Galanov, DV1
Danilenko, OA1
Barantsevich, ER1
Lebedeva, AV1
Belova, AN1
Shprakh, VV1
Bogdanov, EI1
Prokopenko, SV1
Khabirov, FA1
Spirin, NN1
Baliazin, VA1
Miakotnykh, VS1
Volkova, LI1
Gafurov, BG1
Mishchenko, TS1
Toktomushev, CT1
Shyralieva, RK1
Musaev, SK1
Guseinov, SG1
Prabhoo, R1
Keny, S1
Prabhoo, T1
Singh, A1
Rana, R1
Parfenov, VA1
Batysheva, TT1
Bajaj, P1
Arendt-Nielsen, L2
Madeleine, P1
Svensson, P2
Wang, K1
Ribi, C1
Vermeulen, C1
Hauser, C1
Neverov, VA1
Kurbanov, SKh1
Kiss, AM1
Martos, J1
Bastigkeit, M1
Avakian, GN1
Chukanova, EI1
Nikonov, AA1

Trials

6 trials available for tolperisone and Pain

ArticleYear
[The results of the multicenter pharmaco-epidemiological observational project on the use of mydocalm in the treatment of pain syndromes with the muscle spasm].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:12

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Male; Middle Aged; Muscle Relaxants,

2015
A phase IV observational multi-centre, open-label study on efficacy and safety of tolperisone 150 mg in patients with painful muscle spasm associated with degenerative or inflammatory diseases of the musculoskeletal system.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Female; Humans; India; Male; Middle A

2011
Prophylactic tolperisone for post-exercise muscle soreness causes reduced isometric force--a double-blind randomized crossover control study.
    European journal of pain (London, England), 2003, Volume: 7, Issue:5

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Electromyography; Exercise; Humans; Isometric Contra

2003
Effect of muscle relaxants on experimental jaw-muscle pain and jaw-stretch reflexes: a double-blind and placebo-controlled trial.
    European journal of pain (London, England), 2003, Volume: 7, Issue:5

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Humans; Male; Masticatory Muscles; Muscle Relaxants,

2003
Observations with high-dose Mydocalm therapy.
    Therapia Hungarica (English edition), 1993, Volume: 41, Issue:2

    Topics: Adult; Combined Modality Therapy; Female; Humans; Intervertebral Disc Displacement; Male; Middle Age

1993
[The administration of midocalm in the treatment of vertebrogenic algesic syndromes].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2000, Volume: 100, Issue:5

    Topics: Adaptation, Psychological; Adult; Electromyography; Female; Humans; Magnetic Resonance Imaging; Male

2000

Other Studies

6 other studies available for tolperisone and Pain

ArticleYear
[Preventing chronification. So pain isn't branded into memory].
    MMW Fortschritte der Medizin, 2002, May-16, Volume: 144, Issue:20

    Topics: Analgesics; Chronic Disease; Drug Therapy, Combination; Humans; Nociceptors; Pain; Sodium Channel Bl

2002
[Muscular pain and fatigue: is fibromyalgia sticking behind? These points bring it to light].
    MMW Fortschritte der Medizin, 2002, Oct-31, Volume: 144, Issue:44

    Topics: Adult; Chronic Disease; Female; Fibromyalgia; Humans; Male; Middle Aged; Muscle Relaxants, Central;

2002
[Spinal pain and its treatment with midocalm].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Middle Aged; Muscle Relaxants, C

2003
Anaphylactic reactions to tolperisone (Mydocalm).
    Swiss medical weekly, 2003, Jun-28, Volume: 133, Issue:25-26

    Topics: Anaphylaxis; Back Pain; Female; Humans; Middle Aged; Muscle Relaxants, Central; Muscular Diseases; P

2003
[Restorative treatment of degenerative-dystrophic diseases of large joints].
    Vestnik khirurgii imeni I. I. Grekova, 2004, Volume: 163, Issue:2

    Topics: Adult; Female; Humans; Joint Diseases; Male; Middle Aged; Muscle Relaxants, Central; Muscle, Skeleta

2004
[No sodium--no pain. New guidelines in bone and muscle pain].
    MMW Fortschritte der Medizin, 2000, Mar-30, Volume: 142, Issue:13

    Topics: Humans; Muscle Relaxants, Central; Musculoskeletal Diseases; Pain; Parasympatholytics; Piperidines;

2000