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tolperisone and Motor Neuron Disease

tolperisone has been researched along with Motor Neuron Disease in 1 studies

Tolperisone: A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1211)

Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)

Research Excerpts

ExcerptRelevanceReference
"Neurolathyrism is a form of spastic paraparesis caused by the neuroexcitatory amino acid 3-N-oxalyl-L-2,3-diaminopropanoic acid (beta-ODAP) present in the seeds and foliage of Lathyrus sativus."2.67New findings and symptomatic treatment for neurolathyrism, a motor neuron disease occurring in north west Bangladesh. ( De Reuck, J; Haque, A; Hossain, M; Khan, JK; Kuo, YH; Lambein, F, 1994)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haque, A1
Hossain, M1
Khan, JK1
Kuo, YH1
Lambein, F1
De Reuck, J1

Trials

1 trial available for tolperisone and Motor Neuron Disease

ArticleYear
New findings and symptomatic treatment for neurolathyrism, a motor neuron disease occurring in north west Bangladesh.
    Paraplegia, 1994, Volume: 32, Issue:3

    Topics: Bangladesh; Bone Diseases; HTLV-I Antibodies; Humans; Lathyrism; Motor Neuron Disease; Paraparesis,

1994