tolperisone has been researched along with Back Pain in 8 studies
Tolperisone: A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1211)
Back Pain: Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tolperisone is a nonopioid, centrally acting muscle relaxant in clinical development in the USA for the treatment of symptoms associated with acute, painful muscles spasms of the back." | 9.51 | RESUME-1: a Phase III study of tolperisone in the treatment of painful, acute muscle spasms of the back. ( Kaye, R; Torres, K; Vaughan, SA, 2022) |
| "Four patients with anaphylaxis attributed to the intake of the centrally acting muscle relaxant tolperisone hydrochloride (Mydocalm) were observed at the Emergency Department of the Geneva University Hospital between November 2001 and March 2003." | 7.72 | Anaphylactic reactions to tolperisone (Mydocalm). ( Hauser, C; Ribi, C; Vermeulen, C, 2003) |
| "Tolperisone is a nonopioid, centrally acting muscle relaxant in clinical development in the USA for the treatment of symptoms associated with acute, painful muscles spasms of the back." | 5.51 | RESUME-1: a Phase III study of tolperisone in the treatment of painful, acute muscle spasms of the back. ( Kaye, R; Torres, K; Vaughan, SA, 2022) |
| "Four patients with anaphylaxis attributed to the intake of the centrally acting muscle relaxant tolperisone hydrochloride (Mydocalm) were observed at the Emergency Department of the Geneva University Hospital between November 2001 and March 2003." | 3.72 | Anaphylactic reactions to tolperisone (Mydocalm). ( Hauser, C; Ribi, C; Vermeulen, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Vaughan, SA | 1 |
| Torres, K | 1 |
| Kaye, R | 1 |
| Barulin, AE | 1 |
| Kurushina, OV | 1 |
| Ribi, C | 1 |
| Vermeulen, C | 1 |
| Hauser, C | 1 |
| Chernysheva, TV | 1 |
| Bagirova, GG | 1 |
| Vorob'eva, OV | 1 |
| Kozlova, IM | 1 |
| Kumin, M | 1 |
| Saál, M | 1 |
| Ambrózy, G | 1 |
| Ammer, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 3, 14-Day, Double-blind, Randomized, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm[NCT04671082] | Phase 3 | 1,004 participants (Actual) | Interventional | 2020-12-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for tolperisone and Back Pain
| Article | Year |
|---|---|
RESUME-1: a Phase III study of tolperisone in the treatment of painful, acute muscle spasms of the back.
Topics: Back Pain; Female; Humans; Male; Muscle Relaxants, Central; Spasm; Tolperisone; Treatment Outcome | 2022 |
[Comparative effciency of bakloferon and tolperizon central muscle relaxants in complex therapy of back pain].
Topics: Adult; Aged; Back Pain; Baclofen; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Musc | 2006 |
6 other studies available for tolperisone and Back Pain
| Article | Year |
|---|---|
[Complex therapy of acute and chronic back pain with dexalgin].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Combined Modality Therapy; Drug Therapy, | 2012 |
[Back aches often become a chronic problem. Sodium channel block against chronification].
Topics: Back Pain; Ganglia, Spinal; Humans; Muscle Relaxants, Central; Pain Threshold; Secondary Prevention; | 2003 |
Anaphylactic reactions to tolperisone (Mydocalm).
Topics: Anaphylaxis; Back Pain; Female; Humans; Middle Aged; Muscle Relaxants, Central; Muscular Diseases; P | 2003 |
[Midocalm in complex therapy of chronic low back pain syndrome].
Topics: Absorptiometry, Photon; Back Pain; Chronic Disease; Female; Follow-Up Studies; Humans; Male; Middle | 2005 |
Experiences with the combined use of Mydocalm + Donalgin in the treatment of patients suffering from lumboischialgia.
Topics: Adult; Back Pain; Drug Therapy, Combination; Female; Humans; Male; Nicotinic Acids; Niflumic Acid; P | 1984 |
Mydocalm (Tolperison) in the treatment of myogenic dorsal pain.
Topics: Adult; Age Factors; Aged; Back Pain; Female; Humans; Male; Middle Aged; Propiophenones; Tolperisone | 1980 |