Page last updated: 2024-08-17

tolonium chloride and Alzheimer Disease

tolonium chloride has been researched along with Alzheimer Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Cisek, K; Honson, NS; Jensen, JR; Kuret, J1
Hawker, DD; Jansen Labby, K; Mataka, JJ; Silverman, RB; Trippier, PC1
Bulic, B; Mandelkow, E; Pickhardt, M1
Biberoglu, K; Onder, S; Tacal, O; Yuksel, M1
Chandrashekar, M; Chinnathambi, S; Dubey, T1
Akbulut, KG; Biberoglu, K; Onder, S; Tacal, O; Yuksel, M2
Biberoglu, K; Ghasemi, ST; Tacal, O; Tek, MY1
Espinosa, B; Guevara, J; Guzmán, A; Ortiz, A; Rembao, D; Sánchez, A; Zenteno, E1
Wegiel, J; Wisniewski, HM1

Reviews

2 review(s) available for tolonium chloride and Alzheimer Disease

ArticleYear
Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers.
    Journal of medicinal chemistry, 2013, Apr-25, Volume: 56, Issue:8

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Calcium Channels; Drug Combinations; Drug Design; Humans; Huntington Disease; Neurodegenerative Diseases; Nitric Oxide Synthase Type I; Oxidative Stress; Parkinson Disease; Protein Folding; Protein Structure, Quaternary; Proteostasis Deficiencies; Receptors, N-Methyl-D-Aspartate

2013
Progress and developments in tau aggregation inhibitors for Alzheimer disease.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Alzheimer Disease; Animals; Clinical Trials as Topic; Humans; Hydrogen Bonding; Models, Molecular; Protein Binding; Protein Conformation; Structure-Activity Relationship; tau Proteins

2013

Other Studies

8 other study(ies) available for tolonium chloride and Alzheimer Disease

ArticleYear
Ligand polarizability contributes to tau fibril binding affinity.
    Bioorganic & medicinal chemistry, 2011, Sep-01, Volume: 19, Issue:17

    Topics: Alzheimer Disease; Benzothiazoles; Binding Sites; Humans; Indoles; Ligands; Oxindoles; Phenothiazines; Protein Binding; tau Proteins; Thiazoles

2011
Toluidine blue O attenuates tau phosphorylation in N2a-APPSwe cells.
    Chemico-biological interactions, 2022, Oct-01, Volume: 366

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cholinesterase Inhibitors; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Transgenic; Phosphoric Monoester Hydrolases; Phosphorylation; Presenilin-1; Proto-Oncogene Proteins c-akt; tau Proteins; Tolonium Chloride

2022
Photo-Excited Toluidine Blue Disaggregates the Repeat Tau and Modulates End-Binding Protein EB1, Cytoskeletal Structure in Neuronal Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2023, Apr-19, Volume: 57, Issue:2

    Topics: Actins; Alzheimer Disease; Carrier Proteins; Cytoskeleton; Humans; tau Proteins; Tolonium Chloride; Tubulin

2023
Effects of phenothiazine-structured compounds on APP processing in Alzheimer's disease cellular model.
    Biochimie, 2017, Volume: 138

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; CHO Cells; Cholinesterase Inhibitors; Cricetulus; Phenothiazines; Tolonium Chloride

2017
Toluidine blue O modifies hippocampal amyloid pathology in a transgenic mouse model of Alzheimer's disease.
    Biochimie, 2018, Volume: 146

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Transgenic; Phosphorylation; Protein Aggregates; tau Proteins; Tolonium Chloride

2018
Toluidine blue O is a potent inhibitor of human cholinesterases.
    Archives of biochemistry and biophysics, 2016, 08-15, Volume: 604

    Topics: Acetylcholinesterase; Alzheimer Disease; Anions; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Neuroprotective Agents; Phenothiazines; Protein Binding; Regression Analysis; Tolonium Chloride

2016
Toluidine blue-O staining of prion protein deposits.
    Histochemistry and cell biology, 2001, Volume: 116, Issue:6

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Brain Chemistry; Coloring Agents; Creutzfeldt-Jakob Syndrome; Fluorescent Antibody Technique, Indirect; Gerstmann-Straussler-Scheinker Disease; Humans; Immunoenzyme Techniques; Middle Aged; PrPSc Proteins; Sensitivity and Specificity; Staining and Labeling; Tolonium Chloride

2001
The complex of microglial cells and amyloid star in three-dimensional reconstruction.
    Acta neuropathologica, 1990, Volume: 81, Issue:2

    Topics: Aged; Alzheimer Disease; Amyloid; Cerebral Cortex; Female; Humans; Macrophages; Microscopy, Electron; Neuroglia; Tolonium Chloride

1990