tolmetin has been researched along with Uremia in 4 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pritchard, JF | 2 |
| O'Neill, PJ | 2 |
| Affrime, MB | 2 |
| Lowenthal, DT | 2 |
| Dasgupta, A | 2 |
| Volk, A | 1 |
| Timmerman, TG | 1 |
4 other studies available for tolmetin and Uremia
| Article | Year |
|---|---|
Influence of uremia and hemodialysis on the plasma protein binding of tolmetin.
Topics: Adult; Blood Proteins; Fatty Acids, Nonesterified; Female; Humans; Kinetics; Male; Protein Binding; | 1984 |
Influence of uremia, hemodialysis, and nonesterified fatty acids on zomepirac plasma protein binding.
Topics: Adult; Aged; Drug Interactions; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Prote | 1983 |
Displacement of valproic acid and carbamazepine from protein binding in normal and uremic sera by tolmetin, ibuprofen, and naproxen: presence of inhibitor in uremic serum that blocks valproic acid-naproxen interactions.
Topics: Binding, Competitive; Blood Proteins; Carbamazepine; Cyclooxygenase Inhibitors; Drug Interactions; H | 1996 |
In vitro displacement of phenytoin from protein binding by nonsteroidal antiinflammatory drugs tolmetin, ibuprofen, and naproxen in normal and uremic sera.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Humans; Ibuprofen; Naproxen; Phenytoin; Pro | 1996 |