tolmetin has been researched along with Peptic Ulcer in 9 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the risk of hospitalization for gastroduodenal ulcer associated with the use of ketorolac and other non-steroidal anti-inflammatory drugs (NSAIDs)." | 5.08 | Ketorolac use in outpatients and gastrointestinal hospitalization: a comparison with other non-steroidal anti-inflammatory drugs in Italy. ( Da Cas, R; Maggini, M; Menniti-Ippolito, F; Raschetti, R; Traversa, G; Walker, AM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yokoyama, Y | 2 |
| Nakamura, H | 2 |
| Shimizu, M | 2 |
| Motoyoshi, S | 1 |
| Seto, Y | 1 |
| Kadokawa, T | 1 |
| Traversa, G | 2 |
| Walker, AM | 3 |
| Ippolito, FM | 1 |
| Caffari, B | 1 |
| Capurso, L | 1 |
| Dezi, A | 1 |
| Koch, M | 1 |
| Maggini, M | 2 |
| Alegiani, SS | 1 |
| Raschetti, R | 2 |
| Maneatis, TJ | 1 |
| Lewis, RH | 1 |
| Menniti-Ippolito, F | 1 |
| Da Cas, R | 1 |
| Turner, R | 1 |
| Caruso, A | 1 |
| Cutuli, VM | 1 |
| De Bernardis, E | 1 |
| Attaguile, G | 1 |
| Amico-Roxas, M | 1 |
| Wallin, BA | 1 |
| Frank, WO | 1 |
| Young, MD | 1 |
| Jick, H | 1 |
| Jick, SS | 1 |
| Hunter, JR | 1 |
1 trial available for tolmetin and Peptic Ulcer
| Article | Year |
|---|---|
Ketorolac use in outpatients and gastrointestinal hospitalization: a comparison with other non-steroidal anti-inflammatory drugs in Italy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control S | 1998 |
8 other studies available for tolmetin and Peptic Ulcer
| Article | Year |
|---|---|
Gastrointestinal ulcerogenic activity of tolmetin sodium in rats in comparison with those of indomethacin and aspirin.
Topics: Animals; Aspirin; Indomethacin; Male; Peptic Ulcer; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin | 1984 |
[Anti-inflammatory activity of a non-steroidal anti-inflammatory agent, zomepirac sodium, in experimental animals].
Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Per | 1982 |
Gastroduodenal toxicity of different nonsteroidal antiinflammatory drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Case-Control St | 1995 |
Comment: Ketorolac and gastrointestinal ulceration.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Humans; Injections, Intramuscular; Ketor | 1994 |
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethaci | 1977 |
Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Glycine; Lethal Dose | 1992 |
Misoprostol versus cimetidine in tolmetin-induced mucosal injury.
Topics: Alprostadil; Anti-Ulcer Agents; Cimetidine; Gastric Mucosa; Humans; Intestinal Mucosa; Misoprostol; | 1989 |
Follow-up study of tolmetin users.
Topics: Adult; Aged; Aging; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peptic Ulcer; Product Surv | 1989 |