Page last updated: 2024-11-05

tolmetin and Migraine Disorders

tolmetin has been researched along with Migraine Disorders in 10 studies

Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Forty-seven adult patients with migraines enrolled on 50 visits."2.67Ketorolac versus meperidine and hydroxyzine in the treatment of acute migraine headache: a randomized, prospective, double-blind trial. ( Aldag, J; Duarte, C; Dunaway, F; Frederick, R; Turner, L, 1992)
"Ketorolac IM was compared to DHE and metoclopramide IV in migraine patients whose regular abortive medication had failed and who presented to a headache clinic for acute treatment."1.28Ketorolac versus DHE and metoclopramide in the treatment of migraine headaches. ( Klapper, JA; Stanton, JS, 1991)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, CP2
Torre, PR2
Williams, C1
Gray, C1
Barrett, K1
Krucke, G1
Peake, D1
Bass, B2
Kumar, KL1
Mignot, G1
Kopp, C1
Lobo, BL1
Landy, S1
Schafer, NC1
Dave, B1
Seim, MB1
March, JA1
Dunn, KA1
Larkin, G1
Larkin, GL1
Prescott, JE1
Duarte, C1
Dunaway, F1
Turner, L1
Aldag, J1
Frederick, R1
Klapper, JA1
Stanton, JS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Double Blinded Study Comparing Use of Prochlorperazine Versus Prochlorperazine and Ketorolac in the Treatment of Pediatric Migraine in the Emergency Department[NCT01534806]Phase 40 participants (Actual)Interventional2012-01-31Withdrawn (stopped due to Drug is backordered;)
IM Ketorolac vs Diclofenac Potassium Powder for Oral Solution (Cambia) for the Acute Treatment of Severe Migraine[NCT02664116]Phase 440 participants (Anticipated)Interventional2016-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tolmetin and Migraine Disorders

ArticleYear
Recent advances in the acute management of migraine and cluster headaches.
    Journal of general internal medicine, 1994, Volume: 9, Issue:6

    Topics: Analgesics; Butorphanol; Capsaicin; Cluster Headache; Dihydroergotamine; Humans; Ketorolac; Metoclop

1994

Trials

5 trials available for tolmetin and Migraine Disorders

ArticleYear
Ketorolac versus meperidine-plus-promethazine treatment of migraine headache: evaluations by patients.
    The American journal of emergency medicine, 1995, Volume: 13, Issue:2

    Topics: Adult; Analgesics, Non-Narcotic; Double-Blind Method; Drug Combinations; Female; Humans; Ionophores;

1995
Ketorolac as a rapid and effective treatment of migraine headache: evaluations by patients.
    The American journal of emergency medicine, 1993, Volume: 11, Issue:6

    Topics: Acute Disease; Adult; Analgesics; Body Weight; Emergency Service, Hospital; Female; Humans; Injectio

1993
Intravenous ketorolac vs intravenous prochlorperazine for the treatment of migraine headaches.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1998, Volume: 5, Issue:6

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method;

1998
A randomized, double-blind, comparative study of the efficacy of ketorolac tromethamine versus meperidine in the treatment of severe migraine.
    Annals of emergency medicine, 1992, Volume: 21, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Emergencies; F

1992
Ketorolac versus meperidine and hydroxyzine in the treatment of acute migraine headache: a randomized, prospective, double-blind trial.
    Annals of emergency medicine, 1992, Volume: 21, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Female; Humans

1992

Other Studies

4 other studies available for tolmetin and Migraine Disorders

ArticleYear
Drug therapy of migraine.
    The New England journal of medicine, 1994, Apr-07, Volume: 330, Issue:14

    Topics: Analgesics; Emergencies; Humans; Ketorolac; Migraine Disorders; Tolmetin

1994
Recommendations for the emergency treatment of migraine headache.
    Journal of the Tennessee Medical Association, 1994, Volume: 87, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Dexamethasone; Dihydroergotamine; Emergency Me

1994
Intravenous ketorolac vs intravenous prochlorperazine for the treatment of migraine headaches.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1999, Volume: 6, Issue:6

    Topics: Analgesics, Non-Narcotic; Antipsychotic Agents; Female; Humans; Infusions, Intravenous; Ketorolac; M

1999
Ketorolac versus DHE and metoclopramide in the treatment of migraine headaches.
    Headache, 1991, Volume: 31, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dihydroergotamine; Drug Therapy, Combination; Humans; Ketor

1991