tolmetin has been researched along with Macular Edema in 9 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate whether ketorolac ophthalmic drops prescribed four times a day can be associated with improved visual acuity and prompt resolution of edema for patients with pseudophakic cystoid macular edema identified more than 24 months after cataract surgery." | 9.09 | Ketorolac treatment of pseudophakic cystoid macular edema identified more than 24 months after cataract extraction. ( Bressler, NM; Bressler, SB; Schachat, AP; Weisz, JM, 1999) |
| "To report two cases in which cystoid macular edema developed after initiation of topical latanoprost for glaucoma." | 7.70 | Latanoprost-associated cystoid macular edema. ( Callanan, D; Fellman, RL; Savage, JA, 1998) |
| "To evaluate whether ketorolac ophthalmic drops prescribed four times a day can be associated with improved visual acuity and prompt resolution of edema for patients with pseudophakic cystoid macular edema identified more than 24 months after cataract surgery." | 5.09 | Ketorolac treatment of pseudophakic cystoid macular edema identified more than 24 months after cataract extraction. ( Bressler, NM; Bressler, SB; Schachat, AP; Weisz, JM, 1999) |
| "To report two cases in which cystoid macular edema developed after initiation of topical latanoprost for glaucoma." | 3.70 | Latanoprost-associated cystoid macular edema. ( Callanan, D; Fellman, RL; Savage, JA, 1998) |
| "In one eye, the cystoid macular edema was worsened by formation of a dense juxtafoveal epiretinal membrane." | 1.30 | Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. ( Cunningham, ET; Jones, MR; Schwartz, D; Silverstein, BE; Smith, JH; Sykes, SO, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 8 (88.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maguire, AM | 1 |
| Nichols, CW | 1 |
| Crooks, GW | 1 |
| Weinberg, DV | 1 |
| Moorthy, RS | 1 |
| Silverstein, BE | 1 |
| Smith, JH | 1 |
| Sykes, SO | 1 |
| Jones, MR | 1 |
| Schwartz, D | 1 |
| Cunningham, ET | 1 |
| Callanan, D | 1 |
| Fellman, RL | 1 |
| Savage, JA | 1 |
| Flach, AJ | 4 |
| Weisz, JM | 1 |
| Bressler, NM | 1 |
| Bressler, SB | 1 |
| Schachat, AP | 1 |
| Jampol, LM | 1 |
| Weinberg, D | 1 |
| Kraff, MC | 1 |
| Yannuzzi, LA | 1 |
| Campo, RV | 1 |
| Neumann, AC | 1 |
| Cupples, HP | 1 |
| Lefler, WH | 1 |
| Pulido, JS | 1 |
| Stegman, RC | 1 |
| Graham, J | 1 |
| Kruger, LP | 1 |
| Dolan, BJ | 1 |
| Irvine, AR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Topical Corticosteroids and Topical NSAIDs Perioperatively on IL6 Levels in Aqueous Humor and on Incidence of PCME in Patients With NPDR[NCT04940338] | Phase 4 | 90 participants (Actual) | Interventional | 2021-05-01 | Completed | ||
| Changes of Macular Vasculature After Uncomplicated Phacoemulsification Surgery Using Optical Coherence Tomography Angiography[NCT04594603] | 30 participants (Anticipated) | Observational [Patient Registry] | 2021-04-13 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tolmetin and Macular Edema
| Article | Year |
|---|---|
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
4 trials available for tolmetin and Macular Edema
| Article | Year |
|---|---|
Ketorolac treatment of pseudophakic cystoid macular edema identified more than 24 months after cataract extraction.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Chronic Disea | 1999 |
Improvement in visual acuity in chronic aphakic and pseudophakic cystoid macular edema after treatment with topical 0.5% ketorolac tromethamine.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Aphakia; Chronic Disease; Double-B | 1991 |
Prophylaxis of aphakic cystoid macular edema without corticosteroids. A paired-comparison, placebo-controlled double-masked study.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Aphakia, | 1990 |
Effectiveness of ketorolac tromethamine 0.5% ophthalmic solution for chronic aphakic and pseudophakic cystoid macular edema.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aphakia, Postcataract; Chronic Disease; Clinical Trials as | 1987 |
4 other studies available for tolmetin and Macular Edema
| Article | Year |
|---|---|
Visual loss in cytomegalovirus retinitis caused by cystoid macular edema in patients without the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-St | 1996 |
Cystoid macular edema due to cytomegalovirus retinitis in a patient with acquired immune deficiency syndrome.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Age | 1996 |
Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: Acetazolamide; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal | 1998 |
Latanoprost-associated cystoid macular edema.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; G | 1998 |