tolmetin has been researched along with Kidney Diseases in 12 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The time to first administration of rescue analgesic, up to 24 h following dosing with the study medication, was recorded." | 2.67 | A comparison of intramuscular ketorolac and pethidine in the alleviation of renal colic. ( Arkell, DG; Fletcher, MS; Iacovou, JW; Kaisary, AV; Philip, NH; Sandhu, DP, 1994) |
| "Twenty-five patients with renal colic were participants." | 1.29 | The use of intravenous ketorolac for the treatment of renal colic in the emergency department. ( Allegra, JR; Larsen, LS; Miller, A, 1993) |
| "Ketorolac proved safe for short-term intravenous use in children more than 1 year of age when patients with known contraindications to the use of non-steroidal antiinflammatory drugs were excluded." | 1.29 | Safety of intravenous ketorolac therapy in children and cost savings with a unit dosing system. ( Berde, CB; Houck, CS; McDermott, JS; Sethna, NF; Wilder, RT, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 11 (91.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bender, WL | 1 |
| Whelton, A | 1 |
| Beschorner, WE | 1 |
| Darwish, MO | 1 |
| Hall-Craggs, M | 1 |
| Solez, K | 1 |
| Sandhu, DP | 1 |
| Iacovou, JW | 1 |
| Fletcher, MS | 1 |
| Kaisary, AV | 1 |
| Philip, NH | 1 |
| Arkell, DG | 1 |
| Martín Carrasco, C | 1 |
| Rodríguez Vázquez, M | 1 |
| Palacios Garciá, R | 1 |
| Perlmutter, A | 1 |
| Miller, L | 1 |
| Trimble, LA | 1 |
| Marion, DN | 1 |
| Vaughan, ED | 1 |
| Felsen, D | 1 |
| Larsen, LS | 1 |
| Miller, A | 1 |
| Allegra, JR | 1 |
| Cordell, WH | 1 |
| Wright, SW | 1 |
| Wolfson, AB | 1 |
| Timerding, BL | 1 |
| Maneatis, TJ | 1 |
| Lewis, RH | 1 |
| Bynum, L | 1 |
| Nelson, DR | 1 |
| Houck, CS | 1 |
| Wilder, RT | 1 |
| McDermott, JS | 1 |
| Sethna, NF | 1 |
| Berde, CB | 1 |
| Stein, A | 1 |
| Ben Dov, D | 1 |
| Finkel, B | 1 |
| Mecz, Y | 1 |
| Kitzes, R | 1 |
| Lurie, A | 1 |
| Bergus, GR | 1 |
| Cohen, E | 1 |
| Hafner, R | 1 |
| Rotenberg, Z | 1 |
| Fadilla, M | 1 |
| Garty, M | 1 |
| Nicolás Torralba, JA | 1 |
| Rigabert Montiel, M | 1 |
| Bañón Pérez, V | 1 |
| Valdelvira Nadal, P | 1 |
| Pérez Albacete, M | 1 |
| Oosterlinck, W | 1 |
| Philp, NH | 1 |
| Charig, C | 1 |
| Gillies, G | 1 |
| Hetherington, JW | 1 |
| Lloyd, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial Comparing the Combination of Intravenous Lidocaine and Ketorolac to Either Analgesics Alone for ED Patients With Acute Renal Colic[NCT02902770] | Phase 4 | 150 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The trial will compare the patient's pain score on a 11 point Likert scale, ranging from 0 to 10 with 0 being no pain, 5 moderate pain and 10 very severe pain, at 30 minutes (NCT02902770)
Timeframe: 30 minutes
| Intervention | score on a scale (Mean) |
|---|---|
| Lidocaine and Normal Saline Push | 5.52 |
| Ketorolac and Normal Saline Drip | 3.88 |
| Lidocaine and Ketorolac | 3.14 |
8 trials available for tolmetin and Kidney Diseases
| Article | Year |
|---|---|
A comparison of intramuscular ketorolac and pethidine in the alleviation of renal colic.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Colic; Double-B | 1994 |
[A double-blind study of the analgesic efficacy in kidney colic of the combination of dipyrone and spasmolytic with ketorolac trometamol].
Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Butylscopolammonium Bromide; Colic; Dipyrone; Do | 1993 |
Comparison of intravenous ketorolac, meperidine, and both (balanced analgesia) for renal colic.
Topics: Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Double-Blind Method; Dr | 1996 |
Single-dose intramuscular ketorolac versus diclofenac for pain management in renal colic.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Double-Blind Method; Female | 1996 |
Pain relief for renal colic.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Double-Blind Method; Drug | 1996 |
Comparison of ketorolac and diclofenac in the treatment of renal colic.
Topics: Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Coli | 1998 |
[Intramuscular ketorolac compared to subcutaneous tramadol in the initial emergency treatment of renal colic].
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Emergencies; Humans; Injections, Intramuscular; | 1999 |
A double-blind single dose comparison of intramuscular ketorolac tromethamine and pethidine in the treatment of renal colic.
Topics: Adolescent; Adult; Aged; Colic; Double-Blind Method; Drug Administration Schedule; Female; Humans; I | 1990 |
4 other studies available for tolmetin and Kidney Diseases
| Article | Year |
|---|---|
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Biopsy; Female; Fenoprofen; Fluoresce | 1984 |
Toradol, an NSAID used for renal colic, decreases renal perfusion and ureteral pressure in a canine model of unilateral ureteral obstruction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colic; Depression, Chemical; Dinoprostone; Dogs; D | 1993 |
The use of intravenous ketorolac for the treatment of renal colic in the emergency department.
Topics: Adult; Analgesics; Colic; Emergencies; Humans; Injections, Intravenous; Ketorolac; Kidney Diseases; | 1993 |
Safety of intravenous ketorolac therapy in children and cost savings with a unit dosing system.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Prescho | 1996 |