tolmetin has been researched along with Innate Inflammatory Response in 10 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effect of tolmetin sodium(Tol) on acute and subacute exudative inflammation was tested in experimental animals." | 7.66 | [Effect of a non-steroidal anti-inflammatory agent, tolmetin sodium on exudative inflammation in experimental animals (author's transl)]. ( Ishii, K; Motoyoshi, S; Nakamura, H; Shimizu, M; Yokoyama, Y, 1979) |
| "Tolmetin-zinc promotes gain in breaking strength, not by increasing the collagen content, but by favouring better maturation of available collagen at the wound site." | 5.28 | Comparative evaluation of tolmetin & tolmetin-zinc on wound-repair & inflammation. ( Bairy, KL; Kulkarni, DR; Ramesh, KV; Rao, CM, 1990) |
| "In a controlled double blind study the therapeutic efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy] acetic acid (acemetacin, TV 1322, Rantudil¿) and tolmetin were compared in 40 patients suffering from acute and subacute painful irritant conditions in the spinal area and joints." | 5.05 | [Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)]. ( Handrich, L, 1980) |
| "Effect of tolmetin sodium(Tol) on acute and subacute exudative inflammation was tested in experimental animals." | 3.66 | [Effect of a non-steroidal anti-inflammatory agent, tolmetin sodium on exudative inflammation in experimental animals (author's transl)]. ( Ishii, K; Motoyoshi, S; Nakamura, H; Shimizu, M; Yokoyama, Y, 1979) |
| " Footpad PG levels returned to base line or below within 5 min of dosing with ketorolac, which suggests rapid turnover of PG in the inflamed tissue." | 1.30 | Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production. ( Isakson, PC; Portanova, J; Seibert, K; Shaffer, A; Zhang, Y, 1997) |
| "Tolmetin-zinc promotes gain in breaking strength, not by increasing the collagen content, but by favouring better maturation of available collagen at the wound site." | 1.28 | Comparative evaluation of tolmetin & tolmetin-zinc on wound-repair & inflammation. ( Bairy, KL; Kulkarni, DR; Ramesh, KV; Rao, CM, 1990) |
| " After a single topical application of tolmetin gel to the shaved backs of rats, tolmetin was well absorbed percutaneously into the non-inflamed dorsal muscle." | 1.27 | Tolmetin uptake into inflamed tissue in the rat. ( Chasseaud, LF; John, BA; Wood, SG, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdellatif, KRA | 1 |
| Abdelall, EKA | 1 |
| Labib, MB | 1 |
| Fadaly, WAA | 1 |
| Zidan, TH | 1 |
| Wood, SG | 1 |
| John, BA | 1 |
| Chasseaud, LF | 1 |
| McDaniel, DH | 1 |
| Welton, WA | 1 |
| Handrich, L | 1 |
| Chellman, GJ | 1 |
| Lollini, LO | 1 |
| Dorr, AE | 1 |
| DePass, LR | 1 |
| Brook, JW | 1 |
| Boike, A | 1 |
| Zema, RL | 1 |
| Weaver, M | 1 |
| Postak, P | 1 |
| Zhang, Y | 1 |
| Shaffer, A | 1 |
| Portanova, J | 1 |
| Seibert, K | 1 |
| Isakson, PC | 1 |
| Flach, AJ | 1 |
| Dolan, BJ | 1 |
| Donahue, ME | 1 |
| Faktorovich, EG | 1 |
| Gonzalez, GA | 1 |
| Nakamura, H | 1 |
| Yokoyama, Y | 1 |
| Motoyoshi, S | 1 |
| Ishii, K | 1 |
| Shimizu, M | 1 |
| Rao, CM | 1 |
| Ramesh, KV | 1 |
| Bairy, KL | 1 |
| Kulkarni, DR | 1 |
2 trials available for tolmetin and Innate Inflammatory Response
| Article | Year |
|---|---|
[Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Humans; In Vitro Techniques; Ind | 1980 |
Comparative effects of ketorolac 0.5% or diclofenac 0.1% ophthalmic solutions on inflammation after cataract surgery.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; F | 1998 |
8 other studies available for tolmetin and Innate Inflammatory Response
| Article | Year |
|---|---|
Design, synthesis of celecoxib-tolmetin drug hybrids as selective and potent COX-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Catalytic Domain; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 I | 2019 |
Tolmetin uptake into inflamed tissue in the rat.
Topics: Administration, Topical; Animals; Inflammation; Male; Muscles; Pyrroles; Rats; Rats, Inbred Strains; | 1983 |
Furunculosis and hidradenitis suppurativa response.
Topics: Adolescent; Adult; Child; Child, Preschool; Furunculosis; Humans; Inflammation; Pyrroles; Sweat Glan | 1984 |
Comparison of ketorolac tromethamine with other injectable nonsteroidal anti-inflammatory drugs for pain-on-injection and muscle damage in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Drug Combinations; Edema; Hemorrh | 1994 |
1997 William J. Stickel Silver Award. The anti-inflammatory action of locally injected ketorolac.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Awards and Prizes; Disease Models | 1997 |
Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Hyperalgesia; Inflammation; Ketorolac; Male; Rats; | 1997 |
[Effect of a non-steroidal anti-inflammatory agent, tolmetin sodium on exudative inflammation in experimental animals (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cell Differentiation; Edema; | 1979 |
Comparative evaluation of tolmetin & tolmetin-zinc on wound-repair & inflammation.
Topics: Animals; Collagen; Inflammation; Male; Organometallic Compounds; Rats; Tolmetin; Wound Healing | 1990 |