Page last updated: 2024-11-05

tolmetin and Gastric Ulcer

tolmetin has been researched along with Gastric Ulcer in 9 studies

Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.

Research Excerpts

ExcerptRelevanceReference
"To report a case of a perforated gastric ulcer associated with the use of injectable ketorolac tromethamine."3.68Gastric ulcer perforation associated with the use of injectable ketorolac. ( Butwinick, CS; Estes, LL; Fuhs, DW; Heaton, AH, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diamantis, W1
Melton, J1
Sofia, RD1
Ciofalo, VB1
Anderson, NG1
Carson, JR1
Lilley, LL1
Guanci, R1
Yarboro, TL1
Quigley, EM1
Donovan, JP1
Livingston, WC1
Estes, LL1
Fuhs, DW1
Heaton, AH1
Butwinick, CS1
Rainsford, KD1
Whitehouse, MW1
Lanza, FL1
Aspinall, RL1
Swabb, EA1
Davis, RE1
Rack, MF1
Rubin, A1
Ucelay, M1
Lasheras, B1
Cenarruzabeitia, E1

Trials

1 trial available for tolmetin and Gastric Ulcer

ArticleYear
Double-blind, placebo-controlled endoscopic comparison of the mucosal protective effects of misoprostol versus cimetidine on tolmetin-induced mucosal injury to the stomach and duodenum.
    Gastroenterology, 1988, Volume: 95, Issue:2

    Topics: Adult; Alprostadil; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Du

1988

Other Studies

8 other studies available for tolmetin and Gastric Ulcer

ArticleYear
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats.
    Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indometha

1980
Synthesis and biological activity of 5-(4-chlorobenzoyl)-4-(hydroxymethyl)-1-methyl-1H-pyrrole-2-acetic acid, a major metabolite of zomepirac sodium.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:1

    Topics: Analgesics; Animals; Arthritis, Experimental; Humans; In Vitro Techniques; Platelet Aggregation; Pyr

1980
Adverse effects of NSAIDs.
    The American journal of nursing, 1995, Volume: 95, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Female; Humans; Ketorolac; Middle Aged;

1995
Intramuscular Toradol, gastrointestinal bleeding, and peptic ulcer perforation: a case report.
    Journal of the National Medical Association, 1995, Volume: 87, Issue:3

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Drug Combinations; Fema

1995
Ketorolac-related giant gastric ulcers.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ionophores; Ketorolac; Mal

1994
Gastric ulcer perforation associated with the use of injectable ketorolac.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:1

    Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Injections, Intramuscular

1993
Non-steroid anti-inflammatory drugs: combined assay for anti-edemic potency and gastric ulcerogenesis in the same animal.
    Life sciences, 1977, Aug-01, Volume: 21, Issue:3

    Topics: Acacia; Adjuvants, Pharmaceutic; Animals; Aspartic Acid; Aspirin; Carrageenan; Diclofenac; Drug Eval

1977
Pharmacological study of the new nonsteroidal antiinflammatory agent 4'-acetamidophenyl-2-(5'-p-toluyl-1'-methylpyrrole)acetate.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Arthritis, Experimental; Carragee

1988