tolmetin has been researched along with Emesis in 23 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study has attempted to assess postoperative analgesic consumption and nausea and vomiting after general anaesthesia for tonsillectomy using either paracetamol premedication, paracetamol plus a NSAID or intravenous morphine to provide postoperative analgesia." | 9.08 | Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques. ( Mather, SJ; Peutrell, JM, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 9.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| " Postoperative vomiting in the first 24 hr occurred more frequently in the morphine group than in the other groups (P < 0." | 9.08 | Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children. ( Merrick, PM; Purday, JP; Reichert, CC, 1996) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 9.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| "For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery." | 9.07 | A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. ( Nicolson, SC; Schreiner, MS; Weinstein, MS, 1994) |
| "Cyclic vomiting is a rare syndrome that over the years has variously been ascribed to psychogenic causes, sensory seizures, abdominal migraine, and more recently, to mechanical or electrical disturbances in gastric physiology." | 5.29 | Cyclic vomiting: association with multiple homeostatic abnormalities and response to ketorolac. ( Pasricha, PJ; Ravich, WJ; Saudek, CD; Schuster, MM; Wand, G, 1996) |
| " This study has attempted to assess postoperative analgesic consumption and nausea and vomiting after general anaesthesia for tonsillectomy using either paracetamol premedication, paracetamol plus a NSAID or intravenous morphine to provide postoperative analgesia." | 5.08 | Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques. ( Mather, SJ; Peutrell, JM, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 5.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "To compare the incidence of vomiting following codeine or ketorolac for tonsillectomy in children." | 5.08 | Preoperative ketorolac increases bleeding after tonsillectomy in children. ( MacNeill, HB; Reid, CW; Rhine, EJ; Roberts, DW; Splinter, WM, 1996) |
| " Postoperative vomiting in the first 24 hr occurred more frequently in the morphine group than in the other groups (P < 0." | 5.08 | Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children. ( Merrick, PM; Purday, JP; Reichert, CC, 1996) |
| "This prospective, randomized double-blind study was conducted to examine the effect of intraoperative opioid (fentanyl) supplementation on postoperative analgesia, emesis, and recovery in ambulatory patients receiving propofol-nitrous oxide anesthesia." | 5.08 | Recovery after propofol with and without intraoperative fentanyl in patients undergoing ambulatory gynecologic laparoscopy. ( Aasen, M; Frey, K; Pappas, AL; Slogoff, S; Sukhani, R; Vazquez, J, 1996) |
| "05 mg kg(-1) +droperidol 20 microg kg(-1) was given as prophylaxis for postoperative pain and emesis, respectively." | 5.08 | Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy. ( Aasbø, V; Buanes, T; Grøgaard, B; Mjåland, O; Raeder, JC, 1998) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 5.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| "For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery." | 5.07 | A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. ( Nicolson, SC; Schreiner, MS; Weinstein, MS, 1994) |
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "Postoperative pain was assessed by self-report 1." | 2.69 | Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy. ( Ostergaard, D; Rømsing, J; Valentin, N; Walther-Larsen, S, 1998) |
| "Ketorolac tromethamine (Toradol) is a parenteral, nonsteroidal antiinflammatory drug that is being extensively used to provide postoperative analgesia." | 2.68 | Intraoperative ketorolac has an opioid-sparing effect in women after diagnostic laparoscopy but not after laparoscopic tubal ligation. ( Green, CR; Kothary, SP; Levy, L; Pandit, SK; Schork, MA; Tait, AR, 1996) |
| "Postoperative pain was assessed using a visual analogue score (VAS) on 3 separate occasions in recovery." | 2.67 | Intramuscular ketorolac for postoperative analgesia following laparoscopic sterilisation. ( Duffy, BL; Shapiro, MH, 1994) |
| "Postoperative pain was evaluated by the child using a 10-cm linear visual analog scale (VAS) and by a blinded observer using both a VAS and an objective pain scale (OPS) in the postanesthesia care unit (PACU)." | 2.67 | Comparison of ketorolac and morphine as adjuvants during pediatric surgery. ( Jones, MB; Lagueruela, RG; Schweiger, C; Watcha, MF; White, PF, 1992) |
| "Cyclic vomiting is a rare syndrome that over the years has variously been ascribed to psychogenic causes, sensory seizures, abdominal migraine, and more recently, to mechanical or electrical disturbances in gastric physiology." | 1.29 | Cyclic vomiting: association with multiple homeostatic abnormalities and response to ketorolac. ( Pasricha, PJ; Ravich, WJ; Saudek, CD; Schuster, MM; Wand, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gunter, JB | 1 |
| Varughese, AM | 1 |
| Harrington, JF | 1 |
| Wittkugel, EP | 1 |
| Patankar, SS | 1 |
| Matar, MM | 1 |
| Lowe, EE | 1 |
| Myer, CM | 1 |
| Willging, JP | 1 |
| Mather, SJ | 1 |
| Peutrell, JM | 1 |
| Watcha, MF | 2 |
| White, PF | 2 |
| Mendel, HG | 1 |
| Guarnieri, KM | 1 |
| Sundt, LM | 1 |
| Torjman, MC | 1 |
| Jahr, JS | 1 |
| Montalvo, HM | 1 |
| Holton, R | 1 |
| Liukkonen, J | 1 |
| Shapiro, MH | 1 |
| Duffy, BL | 1 |
| Munro, HM | 2 |
| Riegger, LQ | 2 |
| Reynolds, PI | 2 |
| Wilton, NC | 1 |
| Lewis, IH | 1 |
| Geiduschek, JM | 1 |
| Haberkern, CM | 1 |
| McLaughlin, JF | 1 |
| Jacobson, LE | 1 |
| Hays, RM | 1 |
| Roberts, TS | 1 |
| Weinstein, MS | 1 |
| Nicolson, SC | 1 |
| Schreiner, MS | 1 |
| Monagle, J | 1 |
| Wongprasartsuk, P | 1 |
| Shearer, W | 1 |
| Hough, MP | 1 |
| Waugaman, WR | 1 |
| Green, CR | 1 |
| Pandit, SK | 1 |
| Levy, L | 1 |
| Kothary, SP | 1 |
| Tait, AR | 1 |
| Schork, MA | 1 |
| Stein, A | 1 |
| Ben Dov, D | 1 |
| Finkel, B | 1 |
| Mecz, Y | 1 |
| Kitzes, R | 1 |
| Lurie, A | 1 |
| Splinter, WM | 1 |
| Rhine, EJ | 1 |
| Roberts, DW | 1 |
| Reid, CW | 1 |
| MacNeill, HB | 1 |
| Purday, JP | 1 |
| Reichert, CC | 1 |
| Merrick, PM | 1 |
| Pasricha, PJ | 1 |
| Schuster, MM | 1 |
| Saudek, CD | 1 |
| Wand, G | 1 |
| Ravich, WJ | 1 |
| Sukhani, R | 1 |
| Vazquez, J | 1 |
| Pappas, AL | 1 |
| Frey, K | 1 |
| Aasen, M | 1 |
| Slogoff, S | 1 |
| Turner, GA | 1 |
| Anson, N | 1 |
| Williamson, R | 1 |
| Reinhart, DJ | 1 |
| Goldberg, ME | 1 |
| Roth, JV | 1 |
| Dua, R | 1 |
| Nevo, I | 1 |
| Klein, KW | 1 |
| Torjman, M | 1 |
| Vekeman, D | 1 |
| Raeder, JC | 1 |
| Mjåland, O | 1 |
| Aasbø, V | 1 |
| Grøgaard, B | 1 |
| Buanes, T | 1 |
| Rømsing, J | 1 |
| Ostergaard, D | 1 |
| Walther-Larsen, S | 1 |
| Valentin, N | 1 |
| Jones, MB | 1 |
| Lagueruela, RG | 1 |
| Schweiger, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT02973958] | Phase 1 | 30 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| A Randomized Control Trial Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT04646967] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-11-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for tolmetin and Emesis
| Article | Year |
|---|---|
New antiemetic drugs.
Topics: Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; An | 1995 |
Ketorolac and propofol administration for prevention of nausea and vomiting in patients undergoing minor gynecologic surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Genital Diseases, Female | 1993 |
17 trials available for tolmetin and Emesis
| Article | Year |
|---|---|
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recove | 1995 |
The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia; Child; Child, P | 1995 |
Intramuscular ketorolac for postoperative analgesia following laparoscopic sterilisation.
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Humans; Injections, I | 1994 |
Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery.
Topics: Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Method; Female; Hu | 1994 |
A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children.
Topics: Age Factors; Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Metho | 1994 |
Ketorolac versus fentanyl for gynaecological day-case surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia; Female; Fentanyl; Genital Diseases, Female; Human | 1993 |
Intraoperative ketorolac has an opioid-sparing effect in women after diagnostic laparoscopy but not after laparoscopic tubal ligation.
Topics: Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ketorolac Tromethamine; Laparo | 1996 |
Single-dose intramuscular ketorolac versus diclofenac for pain management in renal colic.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Double-Blind Method; Female | 1996 |
Preoperative ketorolac increases bleeding after tonsillectomy in children.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anesthesia, Inhalation; Anesthet | 1996 |
Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; An | 1996 |
Recovery after propofol with and without intraoperative fentanyl in patients undergoing ambulatory gynecologic laparoscopy.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Reco | 1996 |
A comparison of intramuscular ketorolac with indomethacin suppositories in the treatment of pain after oral surgery.
Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethac | 1996 |
Transdermal fentanyl system plus im ketorolac for the treatment of postoperative pain.
Topics: Administration, Cutaneous; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1997 |
Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthetics, D | 1998 |
Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 1998 |
Comparison of ketorolac and morphine as adjuvants during pediatric surgery.
Topics: Adjuvants, Anesthesia; Adolescent; Analgesics; Anesthesia, General; Child; Child, Preschool; Double- | 1992 |
4 other studies available for tolmetin and Emesis
| Article | Year |
|---|---|
Does ketorolac tromethamine, a new analgesic, decrease postoperative recovery time, narcotic requirements, nausea and/or vomiting, and unscheduled hospital admissions: a retrospective analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia Recovery Peri | 1993 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |
Ketorolac and strabismus surgery.
Topics: Analgesics, Non-Narcotic; Humans; Ketorolac; Postoperative Complications; Strabismus; Tolmetin; Vomi | 1996 |
Cyclic vomiting: association with multiple homeostatic abnormalities and response to ketorolac.
Topics: Adrenocorticotropic Hormone; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Mellitus, Type | 1996 |