tolmetin has been researched along with Complication, Postoperative in 52 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether postoperative pain and nausea after laparoscopic sterilization can be reduced with a combination of bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning." | 9.08 | Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. ( Bradford, TH; Meeks, GR; Norman, PF; Robertson, K, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 9.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "This article describes a study that assesses whether patients who received ketorolac tromethamine (Toradol; Syntex Research, Palo Alto, California) during knee surgery had an increased tendency to develop ecchymosis in the lower limb versus patients who did not receive ketorolac tromethamine." | 9.08 | Effect of ketorolac tromethamine (Toradol) on ecchymosis following anterior cruciate ligament reconstruction. ( Dalton, MD; Milne, JC; Russell, JA; Woods, GW, 1995) |
| " Postoperative vomiting in the first 24 hr occurred more frequently in the morphine group than in the other groups (P < 0." | 9.08 | Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children. ( Merrick, PM; Purday, JP; Reichert, CC, 1996) |
| "This double-blind randomized trial assessed the effect of adding an intravenous continuous infusion of ketorolac to a patient-controlled analgesia (PCA) morphine regimen on analgesia, heart rate, arterial blood pressure, and postoperative myocardial ischemia." | 9.08 | The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty. ( Badner, NH; Beattie, WS; Buckley, N; Chan, V; Etches, R; Girard, M; Parsons, D; Warriner, CB, 1997) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 9.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| "For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery." | 9.07 | A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. ( Nicolson, SC; Schreiner, MS; Weinstein, MS, 1994) |
| "0001) and required twice the rescue dosage (p = 0." | 6.68 | Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine. ( Bean-Lijewski, JD; Hunt, RD, 1996) |
| "Ketorolac tromethamine (KT) is a nonsteroidal, antiinflammatory analgesic." | 6.68 | Ketorolac tromethamine and hemorrhage in tonsillectomy: a prospective, randomized, double-blind study. ( Bailey, R; Burgess, LP; Sinha, C, 1997) |
| "To determine whether postoperative pain and nausea after laparoscopic sterilization can be reduced with a combination of bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning." | 5.08 | Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. ( Bradford, TH; Meeks, GR; Norman, PF; Robertson, K, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 5.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "This article describes a study that assesses whether patients who received ketorolac tromethamine (Toradol; Syntex Research, Palo Alto, California) during knee surgery had an increased tendency to develop ecchymosis in the lower limb versus patients who did not receive ketorolac tromethamine." | 5.08 | Effect of ketorolac tromethamine (Toradol) on ecchymosis following anterior cruciate ligament reconstruction. ( Dalton, MD; Milne, JC; Russell, JA; Woods, GW, 1995) |
| "While it appears that ketorolac provides a better postoperative course than either IM or PCA morphine in terms of pain control, postoperative confusion, length of stay, and duration of ileus, 18% of our patients assigned to ketorolac required additional analgesia, and there was a strong patient preference for PCA." | 5.08 | Does patient-controlled analgesia achieve better control of pain and fewer adverse effects than intramuscular analgesia? A prospective randomized trial. ( Avecilla, CS; Berg, RL; Nitschke, LF; Schlösser, CT; Selthafner, JV; Wengert, TJ, 1996) |
| " Postoperative vomiting in the first 24 hr occurred more frequently in the morphine group than in the other groups (P < 0." | 5.08 | Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children. ( Merrick, PM; Purday, JP; Reichert, CC, 1996) |
| "We studied the comparative effects of ketorolac versus bupivacaine supplementation of hydromorphone (HM) patient-controlled epidural analgesia (PCEA) on the HM requirement, postoperative pain, and pulmonary function in 62 consenting patients after thoracotomy procedures." | 5.08 | Effects of ketorolac versus bupivacaine coadministration during patient-controlled hydromorphone epidural analgesia after thoracotomy procedures. ( Bossard, RF; Singh, H; White, PF; Yeatts, RW, 1997) |
| "This double-blind randomized trial assessed the effect of adding an intravenous continuous infusion of ketorolac to a patient-controlled analgesia (PCA) morphine regimen on analgesia, heart rate, arterial blood pressure, and postoperative myocardial ischemia." | 5.08 | The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty. ( Badner, NH; Beattie, WS; Buckley, N; Chan, V; Etches, R; Girard, M; Parsons, D; Warriner, CB, 1997) |
| "05 mg kg(-1) +droperidol 20 microg kg(-1) was given as prophylaxis for postoperative pain and emesis, respectively." | 5.08 | Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy. ( Aasbø, V; Buanes, T; Grøgaard, B; Mjåland, O; Raeder, JC, 1998) |
| " ketorolac and morphine in paediatric outpatients undergoing strabismus surgery." | 5.07 | Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery. ( Lewis, IH; Munro, HM; Reynolds, PI; Riegger, LQ; Wilton, NC, 1994) |
| "For children undergoing inguinal surgery, the administration of a single dose of intravenous morphine after the induction of anesthesia smooths emergence from anesthesia as assessed by improved cooperation and sedation in the PACU, decreases the need for postoperative analgesics, but increases the incidence of vomiting in the first 24 h after surgery." | 5.07 | A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. ( Nicolson, SC; Schreiner, MS; Weinstein, MS, 1994) |
| " For management of postoperative muscle spasm, an intravenous benzodiazepine was used (diazepam 0." | 3.69 | Pain management for children following selective dorsal rhizotomy. ( Geiduschek, JM; Haberkern, CM; Hays, RM; Jacobson, LE; McLaughlin, JF; Roberts, TS, 1994) |
| "Zomepirac sodium is a new nonsteroidal anti-inflammatory agent for management of mild to moderate pain." | 3.66 | Zomepirac-induced renal failure. ( Lacher, JW; Miller, FC; Schorr, WJ, 1983) |
| "Postoperative pain was assessed by self-report 1." | 2.69 | Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy. ( Ostergaard, D; Rømsing, J; Valentin, N; Walther-Larsen, S, 1998) |
| " No adverse events were reported, and there were no significant changes in intraocular pressure in either group." | 2.69 | Comparison of the efficacy and safety of ketorolac tromethamine 0.5% and prednisolone acetate 1% after cataract surgery. ( Jenkins, JE; Pendelton, RA; Simone, JN, 1999) |
| " To ensure participant safety, biomicroscopy, ophthalmoscopy, intraocular pressure, adverse events, and preoperative and postoperative visual acuity and refractive error were also monitored." | 2.69 | Efficacy and safety profile of ketorolac 0.5% ophthalmic solution in the prevention of surgically induced miosis during cataract surgery. ( Cheetham, JK; Grosserode, R; Rosenthal, A; Stewart, R, 1999) |
| "Treatment with ketorolac is completed during hospitalization; therefore, compliance is ensured." | 2.68 | Ketorolac prophylaxis against heterotopic ossification after hip replacement. ( Pritchett, JW, 1995) |
| "0001) and required twice the rescue dosage (p = 0." | 2.68 | Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine. ( Bean-Lijewski, JD; Hunt, RD, 1996) |
| "Ketorolac is a parenteral nonsteroidal antiinflammatory drug (NSAID)." | 2.68 | Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients. ( Bosek, V; Cox, CE, 1996) |
| "Ketorolac tromethamine (KT) is a nonsteroidal, antiinflammatory analgesic." | 2.68 | Ketorolac tromethamine and hemorrhage in tonsillectomy: a prospective, randomized, double-blind study. ( Bailey, R; Burgess, LP; Sinha, C, 1997) |
| "Ketorolac and metamizol were found to be equally safe and effective in reducing postoperative pain after plastic surgery." | 2.68 | A controlled, randomized, double-blind study of ketorolac for postoperative analgesia after plastic surgery. ( Amorrortu-Velayos, J; De Andrés, J; González-Martínez, R; Marín-Bertolín, S; Valia Vera, JC, 1997) |
| "Operative blood losses, postoperative pain, sedation, and on-demand morphine consumption (patient-controlled analgesia [PCA]) were measured." | 2.67 | The effects of perioperative ketorolac infusion on postoperative pain and endocrine-metabolic response. ( Marinangeli, F; Niv, D; Panella, L; Piroli, A; Varrassi, G; Varrassi, S; Wolman, I, 1994) |
| "We describe a case of rapidly appearing acute renal failure following a single intramuscular dose of ketorolac." | 1.29 | Ketorolac induced acute renal failure following a single dose. ( Kayser, SR; Quan, DJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.69) | 18.7374 |
| 1990's | 48 (92.31) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, FC | 1 |
| Schorr, WJ | 1 |
| Lacher, JW | 1 |
| Gunter, JB | 1 |
| Varughese, AM | 1 |
| Harrington, JF | 1 |
| Wittkugel, EP | 1 |
| Patankar, SS | 1 |
| Matar, MM | 1 |
| Lowe, EE | 1 |
| Myer, CM | 1 |
| Willging, JP | 1 |
| Ferraz, AA | 1 |
| Cowles, VE | 1 |
| Condon, RE | 1 |
| Carilli, S | 1 |
| Ezberci, F | 1 |
| Frantzides, CT | 1 |
| Schulte, WJ | 1 |
| Patel, NY | 1 |
| Landercasper, J | 1 |
| Blackburn, A | 1 |
| Stevens, JD | 1 |
| Wheatley, RG | 1 |
| Madej, TH | 1 |
| Hunter, D | 1 |
| Pritchett, JW | 1 |
| Watcha, MF | 1 |
| White, PF | 4 |
| Weale, AE | 1 |
| Warwick, DJ | 1 |
| Durant, N | 1 |
| Prothero, D | 1 |
| Bradford, TH | 1 |
| Robertson, K | 1 |
| Norman, PF | 1 |
| Meeks, GR | 1 |
| Mendel, HG | 1 |
| Guarnieri, KM | 1 |
| Sundt, LM | 1 |
| Torjman, MC | 1 |
| Gallagher, JE | 1 |
| Blauth, J | 1 |
| Fornadley, JA | 1 |
| Milne, JC | 1 |
| Russell, JA | 1 |
| Woods, GW | 1 |
| Dalton, MD | 1 |
| Quan, DJ | 1 |
| Kayser, SR | 1 |
| Munro, HM | 2 |
| Riegger, LQ | 2 |
| Reynolds, PI | 2 |
| Wilton, NC | 1 |
| Lewis, IH | 1 |
| O'Donovan, S | 1 |
| Ferrara, A | 1 |
| Larach, S | 1 |
| Williamson, P | 1 |
| Geiduschek, JM | 1 |
| Haberkern, CM | 1 |
| McLaughlin, JF | 1 |
| Jacobson, LE | 1 |
| Hays, RM | 1 |
| Roberts, TS | 1 |
| Weinstein, MS | 1 |
| Nicolson, SC | 1 |
| Schreiner, MS | 1 |
| Varrassi, G | 1 |
| Panella, L | 1 |
| Piroli, A | 1 |
| Marinangeli, F | 1 |
| Varrassi, S | 1 |
| Wolman, I | 1 |
| Niv, D | 1 |
| Ding, Y | 2 |
| Fredman, B | 1 |
| Kelley, MC | 1 |
| Hocking, MP | 1 |
| Marchand, SD | 1 |
| Sninsky, CA | 1 |
| Montz, FJ | 2 |
| Monk, BJ | 1 |
| Lacy, SM | 1 |
| Fowler, JM | 1 |
| Liu, J | 1 |
| Feinstein, R | 1 |
| Shear, JM | 1 |
| Concannon, MJ | 1 |
| Meng, L | 1 |
| Welsh, CF | 1 |
| Puckett, CL | 1 |
| Hough, MP | 1 |
| Waugaman, WR | 1 |
| Robb, PJ | 1 |
| Rollin, AM | 1 |
| Saunders, DA | 1 |
| Nitschke, LF | 1 |
| Schlösser, CT | 1 |
| Berg, RL | 1 |
| Selthafner, JV | 1 |
| Wengert, TJ | 1 |
| Avecilla, CS | 1 |
| Bean-Lijewski, JD | 1 |
| Hunt, RD | 1 |
| Bosek, V | 1 |
| Cox, CE | 1 |
| Purday, JP | 1 |
| Reichert, CC | 1 |
| Merrick, PM | 1 |
| Bailey, R | 1 |
| Sinha, C | 1 |
| Burgess, LP | 1 |
| Singh, H | 1 |
| Bossard, RF | 1 |
| Yeatts, RW | 1 |
| Beattie, WS | 1 |
| Warriner, CB | 1 |
| Etches, R | 1 |
| Badner, NH | 1 |
| Parsons, D | 1 |
| Buckley, N | 1 |
| Chan, V | 1 |
| Girard, M | 1 |
| Marín-Bertolín, S | 1 |
| De Andrés, J | 1 |
| González-Martínez, R | 1 |
| Valia Vera, JC | 1 |
| Amorrortu-Velayos, J | 1 |
| Raeder, JC | 1 |
| Mjåland, O | 1 |
| Aasbø, V | 1 |
| Grøgaard, B | 1 |
| Buanes, T | 1 |
| De Winter, BY | 1 |
| Boeckxstaens, GE | 1 |
| De Man, JG | 1 |
| Moreels, TG | 1 |
| Herman, AG | 1 |
| Pelckmans, PA | 1 |
| Myles, PS | 1 |
| Power, I | 1 |
| el-Harazi, SM | 1 |
| Ruiz, RS | 1 |
| Feldman, RM | 1 |
| Villanueva, G | 1 |
| Chuang, AZ | 1 |
| Rømsing, J | 1 |
| Ostergaard, D | 1 |
| Walther-Larsen, S | 1 |
| Valentin, N | 1 |
| Holschneider, CH | 1 |
| Nejad, F | 1 |
| Simone, JN | 1 |
| Pendelton, RA | 1 |
| Jenkins, JE | 1 |
| Flach, AJ | 3 |
| Stewart, R | 1 |
| Grosserode, R | 1 |
| Cheetham, JK | 1 |
| Rosenthal, A | 1 |
| O'Hara, DA | 1 |
| Horswell, JL | 1 |
| Fleming, BM | 1 |
| Coombs, DW | 1 |
| Garcha, IS | 1 |
| Bostwick, J | 1 |
| Abe, H | 1 |
| Rodgers, KE | 2 |
| Campeau, JD | 1 |
| Girgis, W | 1 |
| Ellefson, D | 1 |
| DiZerega, GS | 1 |
| Lavelle, CJ | 1 |
| Olander, KW | 1 |
| Retzlaff, JA | 1 |
| Sorenson, LW | 1 |
| Graham, J | 1 |
| Kruger, LP | 1 |
| Stegman, RC | 1 |
| Tanenbaum, L | 1 |
| Smerdon, DL | 1 |
| Hung, SO | 1 |
| Akingbehin, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT02973958] | Phase 1 | 30 participants (Actual) | Interventional | 2017-02-01 | Completed | ||
| A Randomized Control Trial Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision[NCT04646967] | Phase 2 | 100 participants (Anticipated) | Interventional | 2022-11-25 | Recruiting | ||
| Prospective Evaluation of the Effects of IV Ketorolac on Platelet Function Post-Cesarean Delivery[NCT03805607] | Phase 4 | 40 participants (Actual) | Interventional | 2021-01-18 | Active, not recruiting | ||
| A Prospective, Randomized, Control Trial of Ketorolac Versus Placebo on Opioid Analgesic Use, Estimated Blood Loss and Complications Following Cesarean Delivery With Epidural Morphine[NCT02509312] | Phase 4 | 70 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| A Randomized, Double-blinded, Placebo-controlled Study of Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy[NCT03453541] | Phase 4 | 600 participants (Anticipated) | Interventional | 2017-11-21 | Recruiting | ||
| The Effect of Topical Corticosteroids and Topical NSAIDs Perioperatively on IL6 Levels in Aqueous Humor and on Incidence of PCME in Patients With NPDR[NCT04940338] | Phase 4 | 90 participants (Actual) | Interventional | 2021-05-01 | Completed | ||
| Changes of Macular Vasculature After Uncomplicated Phacoemulsification Surgery Using Optical Coherence Tomography Angiography[NCT04594603] | 30 participants (Anticipated) | Observational [Patient Registry] | 2021-04-13 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Total doses of medications to treat pruritus (opioid side-effect) including ondansetron and promethazine. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | doses (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Corrected change in Hct on POD1. Performed by subtracting POD1 Hct from POD0 Hct. Correction for transfusion by further subtracting 3 per unit of pRBC transfused to account for the typical change seen per unit transfused. (NCT02509312)
Timeframe: POD1
| Intervention | mg/dl (Mean) |
|---|---|
| Ketorolac | -5.1 |
| Placebo | -3.5 |
Estimation of blood loss during surgery (NCT02509312)
Timeframe: Immediately post-op
| Intervention | ml (Median) |
|---|---|
| Ketorolac | 900 |
| Placebo | 800 |
Rate of Post-Partum Hemorrhage between groups during the first 24 hours pst-partum. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketorolac | 7 |
| Placebo | 4 |
Total doses of medications to treat pruritus (opioid side-effect) including diphenhydramine, nalbuphine and naloxone. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | doses (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Total hydromorphone doses in mg in the first 24 hours post-partum. (NCT02509312)
Timeframe: 0 - 24 hours post-partum.
| Intervention | mg (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0.2 |
Total number of Units of Packed Reb Blood Cell Transfused in intra-op until 24 hours post-partum. (NCT02509312)
Timeframe: Intra-op until 24 hours post-partum.
| Intervention | units of pRBCs (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Total number of uterotonic doses including methylergonovine, carboprost and misoprostol. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | doses (Median) |
|---|---|
| Ketorolac | 0 |
| Placebo | 0 |
Pain score post-Cesarean Delivery using 11-point numerical rating scale (NRS): 0-10 where 0 is no pain and 10 is the worst pain imaginable (NCT02509312)
Timeframe: Up to 24 hours post-cesarean delivery
| Intervention | units on NRS (Median) | |||||
|---|---|---|---|---|---|---|
| Baseline | 15 mins | 1 hour | 6 hours | 12 hours | 24 hours | |
| Ketorolac | 0 | 0 | 0 | 1 | 2 | 4.5 |
| Placebo | 0 | 0 | 0 | 3 | 3.5 | 5.5 |
Percentile change in diastolic Blood Pressure at 6,12, and 24 hours for each patient's baseline defined by immediate post-op PACU vitals. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | Percent change (Mean) | ||
|---|---|---|---|
| 6 hours | 12 hours | 24 hours | |
| Ketorolac | 12.30 | 8.8 | 12.0 |
| Placebo | 7.6 | 8.8 | 11.1 |
Percentile change in Systolic Blood Pressure at 6,12, and 24 hours for each patient's baseline defined by immediate post-op PACU vitals. (NCT02509312)
Timeframe: 0 - 24 hours post-partum
| Intervention | Percent change (Mean) | ||
|---|---|---|---|
| 6 hours | 12 hours | 24 hours | |
| Ketorolac | -2.0 | -9.10 | -5.9 |
| Placebo | -0.6 | -2.85 | -3.5 |
3 reviews available for tolmetin and Complication, Postoperative
| Article | Year |
|---|---|
New antiemetic drugs.
Topics: Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; An | 1995 |
Ketorolac and propofol administration for prevention of nausea and vomiting in patients undergoing minor gynecologic surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Genital Diseases, Female | 1993 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery.
Topics: Acetazolamide; Administration, Oral; Aged; Aged, 80 and over; Cataract Extraction; Chronic Disease; | 1998 |
30 trials available for tolmetin and Complication, Postoperative
| Article | Year |
|---|---|
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Recovery and complications after tonsillectomy in children: a comparison of ketorolac and morphine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child, Preschool; Double-B | 1995 |
Nonopioid analgesics shorten the duration of postoperative ileus.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Therapy, Combinat | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia; Double | 1995 |
Ketorolac prophylaxis against heterotopic ossification after hip replacement.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female | 1995 |
Is there a clinical interaction between low molecular weight heparin and non-steroidal analgesics after total hip replacement?
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Contusions; Drug Combinat | 1995 |
Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning.
Topics: Analgesics, Non-Narcotic; Bupivacaine; Combined Modality Therapy; Female; Humans; Ketorolac; Laparos | 1995 |
The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia; Child; Child, P | 1995 |
Effect of ketorolac tromethamine (Toradol) on ecchymosis following anterior cruciate ligament reconstruction.
Topics: Adolescent; Adult; Anterior Cruciate Ligament; Anti-Inflammatory Agents, Non-Steroidal; Body Surface | 1995 |
Comparison of the analgesic and emetic properties of ketorolac and morphine for paediatric outpatient strabismus surgery.
Topics: Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Method; Female; Hu | 1994 |
Intraoperative use of Toradol facilitates outpatient hemorrhoidectomy.
Topics: Ambulatory Surgical Procedures; Analgesics; Drug Combinations; Female; Hemorrhoids; Humans; Infusion | 1994 |
A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children.
Topics: Age Factors; Ambulatory Surgical Procedures; Analgesics; Child; Child, Preschool; Double-Blind Metho | 1994 |
The effects of perioperative ketorolac infusion on postoperative pain and endocrine-metabolic response.
Topics: Analgesics; Blood Glucose; Cholecystectomy; Creatinine; Double-Blind Method; Elective Surgical Proce | 1994 |
Use of ketorolac and fentanyl during outpatient gynecologic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Chemotherapy, Adjuvant; Drug Therapy, Combination | 1993 |
Effects of ketorolac on postoperative analgesia and ventilatory function after laparoscopic cholecystectomy.
Topics: Adolescent; Adult; Aged; Analgesics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Hum | 1993 |
Does patient-controlled analgesia achieve better control of pain and fewer adverse effects than intramuscular analgesia? A prospective randomized trial.
Topics: Analgesia, Patient-Controlled; Analgesics; Colon; Confusion; Female; Humans; Injections, Intramuscul | 1996 |
Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bleeding Time; Child; Child, Preschool; Double-Blind M | 1996 |
Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Analysis of Variance; Breast Neoplasms; Double-Bl | 1996 |
Comparative effects of three doses of intravenous ketorolac or morphine on emesis and analgesia for restorative dental surgery in children.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; An | 1996 |
Ketorolac tromethamine and hemorrhage in tonsillectomy: a prospective, randomized, double-blind study.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Hemorrhage; | 1997 |
Effects of ketorolac versus bupivacaine coadministration during patient-controlled hydromorphone epidural analgesia after thoracotomy procedures.
Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Bupiva | 1997 |
The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty.
Topics: Aged; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; E | 1997 |
A controlled, randomized, double-blind study of ketorolac for postoperative analgesia after plastic surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone | 1997 |
Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthetics, D | 1998 |
A randomized double-masked trial comparing ketorolac tromethamine 0.5%, diclofenac sodium 0.1%, and prednisolone acetate 1% in reducing post-phacoemulsification flare and cells.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C | 1998 |
Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 1998 |
Comparison of the efficacy and safety of ketorolac tromethamine 0.5% and prednisolone acetate 1% after cataract surgery.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C | 1999 |
Efficacy and safety profile of ketorolac 0.5% ophthalmic solution in the prevention of surgically induced miosis during cataract surgery.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Double-Blind | 1999 |
The effect of ketorolac tromethamine solution 0.5% in reducing postoperative inflammation after cataract extraction and intraocular lens implantation.
Topics: Adult; Aged; Aged, 80 and over; Anterior Eye Segment; Anti-Inflammatory Agents, Non-Steroidal; Catar | 1988 |
Quantitative assessment of postsurgical breakdown of the blood-aqueous barrier following administration of 0.5% ketorolac tromethamine solution. A double-masked, paired comparison with vehicle-placebo solution study.
Topics: Adult; Aged; Aged, 80 and over; Aqueous Humor; Blood; Cataract Extraction; Double-Blind Method; Drug | 1988 |
Double-blind controlled trial to compare anti-inflammatory effects of tolmetin 2%, prednisolone 0.5%, and placebo in post-cataract extraction eyes.
Topics: Cataract Extraction; Clinical Trials as Topic; Double-Blind Method; Endophthalmitis; Humans; Middle | 1986 |
19 other studies available for tolmetin and Complication, Postoperative
| Article | Year |
|---|---|
Zomepirac-induced renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Arthritis; Back Pain; Body Weight; Coronary Artery Bypass; Creatin | 1983 |
Ketorolac-induced postoperative acute renal failure: a case report.
Topics: Acute Kidney Injury; Analgesics, Non-Narcotic; Fundoplication; Gastroesophageal Reflux; Humans; Inje | 1995 |
Perioperative ketorolac tromethamine and postoperative hemorrhage in cases of tonsillectomy and adenoidectomy.
Topics: Adenoidectomy; Adolescent; Adult; Analgesics; Child; Child, Preschool; Drug Combinations; Female; He | 1995 |
Ketorolac induced acute renal failure following a single dose.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Defibrillators, Imp | 1994 |
Pain management for children following selective dorsal rhizotomy.
Topics: Adolescent; Adult; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Bupiva | 1994 |
Ketorolac prevents postoperative small intestinal ileus in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Transit; Injections, Intraperiton | 1993 |
Ketorolac tromethamine, a nonsteroidal anti-inflammatory drug: ability to inhibit post-radical pelvic surgery adhesions in a porcine model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Combinations; Female; | 1993 |
Inhibition of perioperative platelet aggregation using toradol (ketorolac).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamous Cell; Contraindications; Drug | 1993 |
Diclofenac and post-tonsillectomy haemorrhage.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hemorrhage; Humans; K | 1995 |
Ketorolac and strabismus surgery.
Topics: Analgesics, Non-Narcotic; Humans; Ketorolac; Postoperative Complications; Strabismus; Tolmetin; Vomi | 1996 |
Differential effect of indomethacin and ketorolac on postoperative ileus in rats.
Topics: Animals; Disease Models, Animal; Indomethacin; Intestinal Obstruction; Ketorolac; Nitric Oxide; Nitr | 1998 |
Does ketorolac cause postoperative renal failure: how do we assess the evidence?
Topics: Acute Kidney Injury; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Bas | 1998 |
Immunomodulation with interleukin-10 and interleukin-4 compared with ketorolac tromethamine for prevention of postoperative adhesions in a murine model.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Interleukin-10; In | 1999 |
Bleeding diathesis after perioperative ketorolac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Hemorrhage; Humans; Ketorolac; Postoperati | 1992 |
Bleeding diathesis after perioperative ketorolac.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Hemorrhage; Humans; Ketorolac; Male; | 1992 |
Bleeding diathesis after perioperative ketorolac.
Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Hemorrhagic Disorders; Humans; Ketorolac; | 1991 |
Postoperative hematomas associated with Toradol.
Topics: Analgesics; Hematoma; Humans; Ketorolac; Postoperative Complications; Tolmetin | 1991 |
The effect of intraperitoneal administration of sodium tolmetin-hyaluronic acid on the postsurgical cell infiltration in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Erythrocyte Count; Erythrocytes; Female; Hyaluroni | 1990 |
Nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of postsurgical adhesion.
Topics: Animals; Drug Evaluation, Preclinical; Peritoneal Diseases; Postoperative Complications; Rabbits; Ti | 1990 |