tolmetin has been researched along with Body Weight in 8 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of treatment with hydrochlorothiazide combined with amiloride were compared to hydrochlorothiazide treatment alone in 2 brothers with congenital nephrogenic diabetes insipidus." | 7.67 | Hydrochlorothiazide-amiloride in the treatment of congenital nephrogenic diabetes insipidus. ( Alon, U; Chan, JC, 1985) |
| "The effects of treatment with hydrochlorothiazide combined with amiloride were compared to hydrochlorothiazide treatment alone in 2 brothers with congenital nephrogenic diabetes insipidus." | 3.67 | Hydrochlorothiazide-amiloride in the treatment of congenital nephrogenic diabetes insipidus. ( Alon, U; Chan, JC, 1985) |
| "Zomepirac sodium is a new nonsteroidal anti-inflammatory agent for management of mild to moderate pain." | 3.66 | Zomepirac-induced renal failure. ( Lacher, JW; Miller, FC; Schorr, WJ, 1983) |
| "Both COX inhibitors were toxic to dams in the highest doses evaluated, which caused a significantly greater incidence of intrauterine growth retardation and developmental variations." | 1.32 | Developmental toxicity evaluation of ibuprofen and tolmetin administered in triple daily doses to Wistar CRL:(WI)WUBR rats. ( Burdan, F, 2004) |
| "Ketorolac tromethamine is a relatively new non-steroidal anti-inflammatory drug (NSAID), with potent analgesic activity." | 1.29 | Renal hemodynamic effects of chronic ketorolac tromethamine treatment in aged lean and obese Zucker rats. ( Alavi, FK; Hoff, KK; Zawada, ET, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burdan, F | 1 |
| Miller, FC | 1 |
| Schorr, WJ | 1 |
| Lacher, JW | 1 |
| Alavi, FK | 1 |
| Zawada, ET | 1 |
| Hoff, KK | 1 |
| Davis, CP | 1 |
| Torre, PR | 1 |
| Schafer, NC | 1 |
| Dave, B | 1 |
| Bass, B | 1 |
| Parke, TJ | 1 |
| Lowson, SM | 1 |
| Uncles, DR | 1 |
| Daughtery, MO | 1 |
| Sitzman, BT | 1 |
| Ho, ML | 1 |
| Chang, JK | 1 |
| Wang, GJ | 1 |
| Awouters, F | 1 |
| Niemegeers, CJ | 1 |
| Lenaerts, FM | 1 |
| Janssen, PA | 1 |
| Alon, U | 1 |
| Chan, JC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections: a Prospective Double-Blinded Randomized Trial[NCT04895280] | Phase 4 | 400 participants (Anticipated) | Interventional | 2024-04-30 | Not yet recruiting | ||
| Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial[NCT04115644] | Phase 4 | 82 participants (Actual) | Interventional | 2017-05-01 | Terminated (stopped due to Covid-19 and we failed to submit annual report for 2017 and 2018) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pain as measured by the Visual Analog Scale after first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - immediately after the injection
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.197 |
| Group 2 (Ketorolac) | 3.577 |
| Group 3 (Kenalog) | 3.677 |
Pain as measured by the Visual Analog Scale prior to first injection. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Baseline - pre-injection
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 5.77 |
| Group 2 (Ketorolac) | 4.57 |
| Group 3 (Kenalog) | 4.67 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Day 2
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 2.347 |
| Group 2 (Ketorolac) | 2.837 |
| Group 3 (Kenalog) | 2.67 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 1
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.397 |
| Group 2 (Ketorolac) | 3.7 |
| Group 3 (Kenalog) | 3.257 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 12
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.447 |
| Group 2 (Ketorolac) | 1.417 |
| Group 3 (Kenalog) | 2.027 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 2
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.547 |
| Group 2 (Ketorolac) | 2.67 |
| Group 3 (Kenalog) | 2.57 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 4
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.547 |
| Group 2 (Ketorolac) | 2.67 |
| Group 3 (Kenalog) | 2.317 |
Pain as measured by the Visual Analog Scale. The visual analog scale is a 0-10 scale, 0 being no pain, 10 being unbearable pain. (NCT04115644)
Timeframe: Week 6
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1 (Control) | 3.357 |
| Group 2 (Ketorolac) | 2.757 |
| Group 3 (Kenalog) | 2.687 |
2 trials available for tolmetin and Body Weight
| Article | Year |
|---|---|
Ketorolac as a rapid and effective treatment of migraine headache: evaluations by patients.
Topics: Acute Disease; Adult; Analgesics; Body Weight; Emergency Service, Hospital; Female; Humans; Injectio | 1993 |
Pre-emptive versus post-surgical administration of ketorolac for hysterectomy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic | 1995 |
6 other studies available for tolmetin and Body Weight
| Article | Year |
|---|---|
Developmental toxicity evaluation of ibuprofen and tolmetin administered in triple daily doses to Wistar CRL:(WI)WUBR rats.
Topics: Animals; Aspirin; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; | 2004 |
Zomepirac-induced renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Arthritis; Back Pain; Body Weight; Coronary Artery Bypass; Creatin | 1983 |
Renal hemodynamic effects of chronic ketorolac tromethamine treatment in aged lean and obese Zucker rats.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Dinoprostone; Drug Combination | 1995 |
Effects of ketorolac on bone repair: A radiographic study in modeled demineralized bone matrix grafted rabbits.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bone Matrix | 1998 |
Effects of ketorolac on bone repair: A radiographic study in modeled demineralized bone matrix grafted rabbits.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bone Matrix | 1998 |
Effects of ketorolac on bone repair: A radiographic study in modeled demineralized bone matrix grafted rabbits.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bone Matrix | 1998 |
Effects of ketorolac on bone repair: A radiographic study in modeled demineralized bone matrix grafted rabbits.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bone Matrix | 1998 |
The effects of suprofen in rats with Mycobacterium butyricum-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biometry; Body Weight; Bone and B | 1975 |
Hydrochlorothiazide-amiloride in the treatment of congenital nephrogenic diabetes insipidus.
Topics: Adult; Alkalosis; Amiloride; Body Weight; Child; Diabetes Insipidus; Drug Therapy, Combination; Foll | 1985 |