tolmetin has been researched along with Arthritis in 19 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The glycine amide of tolmetin sodium (TGA) functions as a prodrug and was demonstrated to be more potent than the parent compound as an inhibitor of developing and established adjuvant arthritis in the female Lewis rat." | 7.67 | Effect of tolmetin glycine amide (McN-4366), a prodrug of tolmetin sodium, on adjuvant arthritis in the rat. ( Carson, J; Fisher, MC; Persico, FJ; Pritchard, JF; Wong, S; Yorgey, K, 1988) |
| "The glycine amide of tolmetin sodium (TGA) functions as a prodrug and was demonstrated to be more potent than the parent compound as an inhibitor of developing and established adjuvant arthritis in the female Lewis rat." | 3.67 | Effect of tolmetin glycine amide (McN-4366), a prodrug of tolmetin sodium, on adjuvant arthritis in the rat. ( Carson, J; Fisher, MC; Persico, FJ; Pritchard, JF; Wong, S; Yorgey, K, 1988) |
| "Zomepirac sodium is a new nonsteroidal anti-inflammatory agent for management of mild to moderate pain." | 3.66 | Zomepirac-induced renal failure. ( Lacher, JW; Miller, FC; Schorr, WJ, 1983) |
| "The data obtained from 5-day and long-term evaluations of acetaminophen (APAP) using the adjuvant arthritis rat model, demonstrated the anti-inflammatory and antiarthritic activities of APAP." | 3.66 | Anti-inflammatory and antiarthritic evaluation of acetaminophen and its potentiation of tolmetin. ( Gardocki, JF; Wong, S, 1983) |
| "Aspirin remains the agent of first choice, but ibuprofen, fenoprofen, naproxen and tolmetin are useful drugs in rheumatoid arthritis." | 3.66 | Nonsteroidal anti-inflammatory agents in arthritis. ( Ridolfo, AS, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, FC | 1 |
| Schorr, WJ | 1 |
| Lacher, JW | 1 |
| Herman, JH | 1 |
| Hess, EV | 1 |
| Bhalla, AK | 1 |
| Simon, LS | 2 |
| Sotsky, SM | 1 |
| Tossell, JW | 1 |
| Wong, S | 2 |
| Gardocki, JF | 1 |
| Nakamura, H | 2 |
| Yokoyama, Y | 2 |
| Ishii, K | 2 |
| Motoyoshi, S | 2 |
| Seto, Y | 2 |
| Shimizu, M | 2 |
| Imazu, C | 1 |
| Mills, JA | 1 |
| Nash, DP | 1 |
| Sack, KE | 1 |
| Langlois, R | 1 |
| Paquette, D | 1 |
| Zivony, D | 1 |
| Nocton, J | 1 |
| Wortmann, D | 1 |
| Esterly, N | 1 |
| Irwin, MG | 1 |
| Cheung, KM | 1 |
| Nicholls, JM | 1 |
| Thompson, N | 1 |
| Swift, JQ | 1 |
| Roszkowski, MT | 1 |
| Alton, T | 1 |
| Hargreaves, KM | 1 |
| Ridolfo, AS | 1 |
| Healey, LA | 1 |
| Persico, FJ | 1 |
| Pritchard, JF | 1 |
| Fisher, MC | 1 |
| Yorgey, K | 1 |
| Carson, J | 1 |
2 reviews available for tolmetin and Arthritis
| Article | Year |
|---|---|
Nonsteroidal anti-inflammatory drugs and modulation of cartilaginous changes in osteoarthritis and rheumatoid arthritis. Clinical implications.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Bone Resorption; Cartilage, Articular; Collagen; Human | 1984 |
Nonsteroidal antiinflammatory drugs (second of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic | 1980 |
17 other studies available for tolmetin and Arthritis
| Article | Year |
|---|---|
Zomepirac-induced renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Arthritis; Back Pain; Body Weight; Coronary Artery Bypass; Creatin | 1983 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids | 1984 |
Tolmetin induction of mania.
Topics: Arthritis; Bipolar Disorder; Female; Humans; Middle Aged; Psychoses, Substance-Induced; Pyrroles; To | 1984 |
Anti-inflammatory and antiarthritic evaluation of acetaminophen and its potentiation of tolmetin.
Topics: Acetaminophen; Animals; Arthritis; Arthritis, Experimental; Drug Evaluation, Preclinical; Drug Thera | 1983 |
[Effect of a non-steroidal anti-inflammatory drug, tolmetin sodium on arthritic pain, traumatic edema and LPS-induced fever (author's transl)].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Edema; Fever; Lipopolysaccharides; Male | 1981 |
[Analgesic activity of a non-steroidal antiinflammatory drug, zomepirac sodium, in experimental animals].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; B | 1982 |
Current review and comparison of the new nonsteroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Drug Administration Schedule; Fenoprofen | 1980 |
Arthritis: specifics on long-term management. Part II.
Topics: Anti-Inflammatory Agents; Arthritis; Gold; Humans; Immunosuppressive Agents; Indomethacin; Penicilla | 1980 |
Increased serum lithium levels due to ketorolac therapy.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bipolar Disorder; Drug | 1994 |
Juvenile Reiter's syndrome: a report of four cases.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, | 1998 |
Intra-articular injection of ketorolac in the rat knee joint: effect on articular cartilage and synovium.
Topics: Analgesics; Animals; Arthritis; Cartilage, Articular; Cyclooxygenase Inhibitors; Injections, Intra-A | 1998 |
Effect of intra-articular versus systemic anti-inflammatory drugs in a rabbit model of temporomandibular joint inflammation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bradykinin; D | 1998 |
Nonsteroidal anti-inflammatory agents in arthritis.
Topics: Administration, Oral; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Dose-Resp | 1978 |
New drugs for arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Drug Interactions; Fenoprofen; Humans; Naproxen; Tolmetin | 1976 |
New drugs for arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Drug Interactions; Fenoprofen; Humans; Naproxen; Tolmetin | 1976 |
More on the new arthritis drugs.
Topics: Arthritis; Fenoprofen; Humans; Ibuprofen; Naproxen; Tolmetin | 1976 |
Effect of tolmetin glycine amide (McN-4366), a prodrug of tolmetin sodium, on adjuvant arthritis in the rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Bone and Bones; Digestive System; Female; Indomethacin; | 1988 |