tolmetin has been researched along with Arthritis, Degenerative in 24 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicentered study was carried out, under double-blind conditions, on 160 elderly patients afflicted with differently localized symptomatic osteoarthritis, for the purpose of evaluating the therapeutical efficacy and tolerability of ST-679 (per-os at a dose of 1200 mg pro die in 80 patients) and to compare them with those of tolmetin (per os at a dose of 1200 mg pro die in 80 patients)." | 9.07 | [An evaluation of the therapeutic activity and tolerance of ST-679 in patients with osteoarthritis at different sites. A controlled double-blind study vs tolmetin]. ( Ciarimboli, M; Donati, G; Garzya, G; Imparato, L; Lingetti, M; Nolfe, G; Porfido, FA; Saraceni, G; Sorrentino, GP, 1993) |
| "An open, multi-centre study was carried out in patients with various moderate to severe painful conditions to assess the effectiveness of zomepirac in relieving pain." | 9.05 | A multi-centre study of zomepirac in painful conditions: an analysis of clinical data for 15,484 patients. ( Jefferson, WL; Steele, CE, 1983) |
| "One hundred forty-one subjects with osteoarthritis completed this double-blind, multicenter, crossover trial comparing four nonsteroidal anti-inflammatory (NSAI) agents after single-blind aspirin stabilization." | 9.05 | Four-way, multicenter, crossover trial of ibuprofen, fenoprofen calcium, naproxen, and tolmetin sodium in osteoarthritis: comparative clinical profiles. ( Caldwell, JR; Crain, D; Hoffmeister, RT; Kantrowitz, F; Lloyd, RJ; Nussdorf, RT; Repice, MR; Schmid, FR, 1983) |
| "In order to evaluate the effectiveness and safety of tolmetin sodium in the treatment of both rheumatoid arthritis (RA) and osteoarthritis in geriatric patients, a retrospective study was made of patients 65 years and older who participated in long-term, controlled, double-blind and open trials during both the investigational period and since marketing of the drug." | 9.05 | Long-term efficacy and safety of tolmetin sodium in treatment of geriatric patients with rheumatoid arthritis and osteoarthritis: a retrospective study. ( O'Brien, WM, 1983) |
| " Patients were allocated at random to treatment with either 800 mg tolmetin sodium daily or 500 mg naproxen daily over a period of 12 weeks, both drugs being given in identical capsule form in a dosage of 2 capsules twice daily." | 6.65 | A double-blind comparative evaluation of tolmetin versus naproxen in osteoarthritis. ( Bach-Andersen, R; Persson, B; Telhag, H, 1981) |
| "A multicentered study was carried out, under double-blind conditions, on 160 elderly patients afflicted with differently localized symptomatic osteoarthritis, for the purpose of evaluating the therapeutical efficacy and tolerability of ST-679 (per-os at a dose of 1200 mg pro die in 80 patients) and to compare them with those of tolmetin (per os at a dose of 1200 mg pro die in 80 patients)." | 5.07 | [An evaluation of the therapeutic activity and tolerance of ST-679 in patients with osteoarthritis at different sites. A controlled double-blind study vs tolmetin]. ( Ciarimboli, M; Donati, G; Garzya, G; Imparato, L; Lingetti, M; Nolfe, G; Porfido, FA; Saraceni, G; Sorrentino, GP, 1993) |
| "An open, multi-centre study was carried out in patients with various moderate to severe painful conditions to assess the effectiveness of zomepirac in relieving pain." | 5.05 | A multi-centre study of zomepirac in painful conditions: an analysis of clinical data for 15,484 patients. ( Jefferson, WL; Steele, CE, 1983) |
| "One hundred forty-one subjects with osteoarthritis completed this double-blind, multicenter, crossover trial comparing four nonsteroidal anti-inflammatory (NSAI) agents after single-blind aspirin stabilization." | 5.05 | Four-way, multicenter, crossover trial of ibuprofen, fenoprofen calcium, naproxen, and tolmetin sodium in osteoarthritis: comparative clinical profiles. ( Caldwell, JR; Crain, D; Hoffmeister, RT; Kantrowitz, F; Lloyd, RJ; Nussdorf, RT; Repice, MR; Schmid, FR, 1983) |
| "In order to evaluate the effectiveness and safety of tolmetin sodium in the treatment of both rheumatoid arthritis (RA) and osteoarthritis in geriatric patients, a retrospective study was made of patients 65 years and older who participated in long-term, controlled, double-blind and open trials during both the investigational period and since marketing of the drug." | 5.05 | Long-term efficacy and safety of tolmetin sodium in treatment of geriatric patients with rheumatoid arthritis and osteoarthritis: a retrospective study. ( O'Brien, WM, 1983) |
| " The first compared tolmetin sodium, phenylbutazone and placebo in rheumatoid arthritis." | 5.05 | Clinical experience with tolmetin sodium. ( Balme, HW; Huskisson, EC; Wojtulewski, JA, 1980) |
| "The new antirheumatic agents, fenoprofen calcium, naproxen, and tolmetin sodium, are effective in the management of rheumatoid arthritis." | 3.65 | New antirheumatic agents: Fenoprofen calcium (Nalfon), naproxen (Naprosyn), and tolmetin sodium (Tolectin). ( Lewis, JR, 1977) |
| " Patients were allocated at random to treatment with either 800 mg tolmetin sodium daily or 500 mg naproxen daily over a period of 12 weeks, both drugs being given in identical capsule form in a dosage of 2 capsules twice daily." | 2.65 | A double-blind comparative evaluation of tolmetin versus naproxen in osteoarthritis. ( Bach-Andersen, R; Persson, B; Telhag, H, 1981) |
| "Oxaprozin is an effective, long-acting anti-inflammatory analgesic, but its comparative advantages remain undefined." | 2.39 | A review of selected newer nonsteroidal anti-inflammatory drugs. ( Amadio, P; Cummings, DM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (91.67) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steele, CE | 3 |
| Jefferson, WL | 1 |
| Caldwell, JR | 1 |
| Crain, D | 1 |
| Hoffmeister, RT | 1 |
| Kantrowitz, F | 1 |
| Lloyd, RJ | 1 |
| Nussdorf, RT | 1 |
| Schmid, FR | 1 |
| Repice, MR | 1 |
| O'Brien, WM | 1 |
| Altman, RD | 1 |
| Herman, JH | 1 |
| Hess, EV | 1 |
| Ginsberg, F | 1 |
| Famaey, JP | 1 |
| Schlumpf, U | 1 |
| Davies, J | 1 |
| Dixon, AS | 1 |
| Balme, HW | 1 |
| Wojtulewski, JA | 1 |
| Huskisson, EC | 1 |
| Telhag, H | 1 |
| Bach-Andersen, R | 1 |
| Persson, B | 1 |
| Shephard, NW | 1 |
| Bird, HA | 1 |
| Rhind, VM | 1 |
| Leatham, PA | 1 |
| Wright, V | 1 |
| Katz, SM | 1 |
| Capaldo, R | 1 |
| Everts, EA | 1 |
| DiGregorio, JG | 1 |
| Fellmann, N | 1 |
| Pavletic, B | 1 |
| Cummings, DM | 2 |
| Amadio, P | 2 |
| Lingetti, M | 1 |
| Ciarimboli, M | 1 |
| Porfido, FA | 1 |
| Imparato, L | 1 |
| Sorrentino, GP | 1 |
| Garzya, G | 1 |
| Saraceni, G | 1 |
| Donati, G | 1 |
| Nolfe, G | 1 |
| Lewis, JR | 1 |
| Müller, FO | 1 |
| Gosling, JA | 1 |
| Erdmann, GH | 1 |
| Maibach, E | 2 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Pavelka, K | 1 |
| Susta, A | 1 |
| Macauley, D | 1 |
5 reviews available for tolmetin and Arthritis, Degenerative
| Article | Year |
|---|---|
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Toleran | 1984 |
Nonsteroidal anti-inflammatory drugs and modulation of cartilaginous changes in osteoarthritis and rheumatoid arthritis. Clinical implications.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Bone Resorption; Cartilage, Articular; Collagen; Human | 1984 |
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe | 1982 |
A review of selected newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; | 1994 |
Tolmetin: a review of its pharmacological properties and therapeutic efficacy in rheumatic diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Blood | 1978 |
15 trials available for tolmetin and Arthritis, Degenerative
| Article | Year |
|---|---|
A multi-centre study of zomepirac in painful conditions: an analysis of clinical data for 15,484 patients.
Topics: Adolescent; Adult; Aged; Back Pain; Clinical Trials as Topic; Dose-Response Relationship, Drug; Fema | 1983 |
Four-way, multicenter, crossover trial of ibuprofen, fenoprofen calcium, naproxen, and tolmetin sodium in osteoarthritis: comparative clinical profiles.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Fenopro | 1983 |
Long-term efficacy and safety of tolmetin sodium in treatment of geriatric patients with rheumatoid arthritis and osteoarthritis: a retrospective study.
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Os | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Toleran | 1984 |
Tolmetin sodium and indomethacin in the treatment of osteoarthrosis of the hip: a double-blind crossover study.
Topics: Activities of Daily Living; Aged; Clinical Trials as Topic; Double-Blind Method; Hip; Humans; Indome | 1980 |
Clinical experience with tolmetin sodium.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Fibro | 1980 |
A double-blind comparative evaluation of tolmetin versus naproxen in osteoarthritis.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Naproxen; Osteoarthritis; Pain; | 1981 |
Comparison of tolmetin sodium with indomethacin in osteoarthritis.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Hip Joint; Humans; Indomethacin; Knee Joint; O | 1981 |
[Double-blind study with the antirheumatic tolmetin in the treatment of inpatients with osteoarthritis of hips and knees (author's transl)].
Topics: Double-Blind Method; Drug Evaluation; Female; Hip; Humans; Knee; Male; Osteoarthritis; Placebos; Pyr | 1980 |
[An evaluation of the therapeutic activity and tolerance of ST-679 in patients with osteoarthritis at different sites. A controlled double-blind study vs tolmetin].
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Interaction | 1993 |
A comparison of tolmetin with aspirin in the treatment of osteo-arthritis of the knee.
Topics: Aspirin; Clinical Trials as Topic; Humans; Knee Joint; Osteoarthritis; Pyrroles; Tolmetin | 1977 |
[Therapy of arthroses of the hip and knee with tolectin (author's transl)].
Topics: Adult; Aged; Animals; Clinical Trials as Topic; Drug Evaluation; Female; Hip Joint; Humans; Joint Di | 1977 |
[Long-term administration of tolmetin in patients with osteoarthritis. Overt controled trial].
Topics: Clinical Trials as Topic; Female; Humans; Long-Term Care; Male; Middle Aged; Osteoarthritis; Pyrrole | 1978 |
European experiences with tolmetin in the treatment of rheumatic diseases.
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Ag | 1976 |
The effect of tolmetin on the chronic pain and decreased functional capacity associated with degenerative joint disease.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; M | 1985 |
5 other studies available for tolmetin and Arthritis, Degenerative
| Article | Year |
|---|---|
[Double-blind study of tolmetin osteoarthritis (author's transl)].
Topics: Adult; Aged; Back Pain; Double-Blind Method; Humans; Middle Aged; Naproxen; Osteoarthritis; Pyrroles | 1980 |
Non-steroidals ineffective in OA.
Topics: Humans; Ibuprofen; Osteoarthritis; Placebos; Pyrroles; Tolmetin | 1982 |
Tolmetin. Association with reversible renal failure and acute interstitial nephritis.
Topics: Acute Disease; Acute Kidney Injury; Aged; Biopsy; Female; Humans; Kidney; Nephritis, Interstitial; O | 1981 |
New antirheumatic agents: Fenoprofen calcium (Nalfon), naproxen (Naprosyn), and tolmetin sodium (Tolectin).
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Gastrointestinal Hemorrhage; H | 1977 |
Worldwide experience with diclofenac in rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Humans; Indomethacin; Naproxen; Ost | 1985 |