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tolmetin and Allergic Conjunctivitis

tolmetin has been researched along with Allergic Conjunctivitis in 12 studies

Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.

Research Excerpts

ExcerptRelevanceReference
"The therapeutic utility of cyclooxygenase (CO) inhibitors, such as ketorolac, in reducing the inflammatory events associated with allergic conjunctivitis is not unexpected since prostanoids (PG) elicit conjunctival redness (PGD2, PGE2, PGF2 alpha), edema (PGD2, TxA2), eosinophil infiltration (PGD2, PGJ2) and mucous cell discharge (PGD2, PGJ2, TxA2)."3.69The pruritogenic and inflammatory effects of prostanoids in the conjunctiva. ( Hawley, SB; Joseph, R; Merlino, GF; Nieves, AL; Spada, CS; Woodward, DF, 1995)
"Topically administered ketorolac (Acular), a cyclooxygenase inhibitor, has recently been reported as clinically beneficial for treating allergic conjunctivitis."3.69Characterization of receptor subtypes involved in prostanoid-induced conjunctival pruritus and their role in mediating allergic conjunctival itching. ( Friedlaender, MH; Nieves, AL; Woodward, DF, 1996)
"Ketorolac treated eyes showed 50."2.68Topical ketorolac 0.5% solution for the treatment of vernal keratoconjunctivitis. ( Gupta, A; Gupta, R; Ram, J; Sharma, A, 1997)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwab, IR1
Holdcroft, C1
Lamon, EC1
Meijer, F1
Ruijter, JM1
Van Delft, JL1
Van Haeringen, NJ1
Woodward, DF2
Nieves, AL2
Hawley, SB1
Joseph, R1
Merlino, GF1
Spada, CS1
Sitenga, GL1
Ing, EB1
Van Dellen, RG1
Younge, BR1
Leavitt, JA1
Joseph Titi, M1
Friedlaender, MH2
Sharma, A1
Gupta, R1
Ram, J1
Gupta, A1
Tauber, J1
Raizman, MB1
Ostrov, CS1
Laibovitz, RA1
Abelson, MB1
Betts, JG1
Koester, JM1
Gill, D1
Schaich, L1

Reviews

1 review available for tolmetin and Allergic Conjunctivitis

ArticleYear
A critical look at ocular allergy drugs.
    American family physician, 1996, Volume: 53, Issue:8

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Allergic; Histamine H1 Antagoni

1996

Trials

3 trials available for tolmetin and Allergic Conjunctivitis

ArticleYear
Contact lens induced conjunctivitis: a model of human ocular inflammation.
    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 1996, Volume: 22, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Conjunctiva; Conjunctivitis, Aller

1996
Topical ketorolac 0.5% solution for the treatment of vernal keratoconjunctivitis.
    Indian journal of ophthalmology, 1997, Volume: 45, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, P

1997
A multicenter comparison of the ocular efficacy and safety of diclofenac 0.1% solution with that of ketorolac 0.5% solution in patients with acute seasonal allergic conjunctivitis.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1998, Volume: 14, Issue:2

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Allergic; Diclofenac;

1998

Other Studies

8 other studies available for tolmetin and Allergic Conjunctivitis

ArticleYear
Nonsteroidal eye drops for ocular allergy.
    The Western journal of medicine, 1994, Volume: 161, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Allergic; Drug Combinations; Histamine H1 A

1994
Ketorolac: a new antiinflammatory for seasonal allergic conjunctivitis.
    The Nurse practitioner, 1994, Volume: 19, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Allergic; Humans; Ketorolac; Ophthalmic Sol

1994
Conjunctivitis treatment.
    Pediatric annals, 1993, Volume: 22, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Conjunctivitis, Allergic; Cromolyn

1993
Ketorolac for seasonal allergic conjunctivitis.
    The Medical letter on drugs and therapeutics, 1993, Sep-17, Volume: 35, Issue:905

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Conjunctivitis, Allergic; Drug Combinations; Humans; Ketoro

1993
Nitric oxide induces vascular permeability changes in the guinea pig conjunctiva.
    European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2

    Topics: Albumins; Animals; Arginine; Capillary Permeability; Conjunctiva; Conjunctivitis, Allergic; Enzyme I

1995
The pruritogenic and inflammatory effects of prostanoids in the conjunctiva.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Fall, Volume: 11, Issue:3

    Topics: Animals; Capillary Permeability; Conjunctiva; Conjunctivitis, Allergic; Cyclooxygenase Inhibitors; D

1995
Asthma caused by topical application of ketorolac.
    Ophthalmology, 1996, Volume: 103, Issue:6

    Topics: Administration, Topical; Adult; Albuterol; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-S

1996
Characterization of receptor subtypes involved in prostanoid-induced conjunctival pruritus and their role in mediating allergic conjunctival itching.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1

    Topics: Animals; Conjunctivitis, Allergic; Female; Guinea Pigs; Ketorolac; Male; Prostaglandins; Pruritus; R

1996