tolmetin and Aging
tolmetin has been researched along with Aging in 5 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The absorption of ketorolac is rapid, Cmax being attained between 20 to 60 min." | 2.38 | Clinical pharmacokinetics of ketorolac tromethamine. ( Brocks, DR; Jamali, F, 1992) |
| "Ketorolac tromethamine is a relatively new non-steroidal anti-inflammatory drug (NSAID), with potent analgesic activity." | 1.29 | Renal hemodynamic effects of chronic ketorolac tromethamine treatment in aged lean and obese Zucker rats. ( Alavi, FK; Hoff, KK; Zawada, ET, 1995) |
| "Ketorolac tromethamine is a nonsteroidal, analgesic, anti-inflammatory, antipyretic investigational drug with anti-prostaglandin synthetase activity." | 1.28 | Pharmacokinetics of single-dose oral and intramuscular ketorolac tromethamine in the young and elderly. ( Garg, DC; Jallad, NS; Martinez, JJ; Mroszczak, EJ; Weidler, DJ, 1990) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Alavi, FK | 1 |
| Zawada, ET | 1 |
| Hoff, KK | 1 |
| Fowler, CJ | 1 |
| Janson, U | 1 |
| Johnson, RM | 1 |
| Wahlström, G | 1 |
| Stenström, A | 1 |
| Norström, K | 1 |
| Tiger, G | 1 |
| Brocks, DR | 1 |
| Jamali, F | 1 |
| Jallad, NS | 1 |
| Garg, DC | 1 |
| Martinez, JJ | 1 |
| Mroszczak, EJ | 1 |
| Weidler, DJ | 1 |
| Jick, H | 1 |
| Jick, SS | 1 |
| Hunter, JR | 1 |
| Walker, AM | 1 |
Reviews
1 review available for tolmetin and Aging
| Article | Year |
|---|---|
Clinical pharmacokinetics of ketorolac tromethamine.
Topics: Absorption; Aging; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Inte | 1992 |
Other Studies
4 other studies available for tolmetin and Aging
| Article | Year |
|---|---|
Renal hemodynamic effects of chronic ketorolac tromethamine treatment in aged lean and obese Zucker rats.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Dinoprostone; Drug Combination | 1995 |
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.
Topics: Aging; Animals; Arachidonic Acids; Brain; Cell Extracts; Cell Survival; Dose-Response Relationship, | 1999 |
Pharmacokinetics of single-dose oral and intramuscular ketorolac tromethamine in the young and elderly.
Topics: Administration, Oral; Adult; Aged; Aging; Blood Proteins; Drug Combinations; Female; Half-Life; Huma | 1990 |
Follow-up study of tolmetin users.
Topics: Adult; Aged; Aging; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peptic Ulcer; Product Surv | 1989 |