tolfenamic-acid has been researched along with Nausea* in 1 studies
1 trial(s) available for tolfenamic-acid and Nausea
| Article | Year |
|---|---|
Tolfenamic acid is as effective as ergotamine during migraine attacks.
Tolfenamic acid (a potent inhibitor of prostaglandin biosynthesis), ergotamine tartrate, acetylsalicylic acid, or placebo was administered during 160 migraine attacks in twenty women in a double-blind, cross-over study. Tolfenamic acid and ergotamine were equally effective in reducing the duration and intensity of attacks, but side-effects, especially nausea, were less common with tolfenamic acid. This probably accounted for the patients' preference for tolfenamic acid. The effectiveness of tolfenamic acid in acute migraine attacks accords with the postulated role of prostaglandins in migraine. Topics: Adolescent; Adult; Aspirin; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Consumer Behavior; Double-Blind Method; Drug Evaluation; Ergotamine; Female; Humans; Middle Aged; Migraine Disorders; Nausea; ortho-Aminobenzoates; Placebos; Prostaglandin Antagonists; Vasoconstrictor Agents | 1979 |