tolbutamide has been researched along with Viral Hepatitis, Human in 2 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A pharmacokinetic model that incorporates linear binding of drug to plasma proteins and tissue indicates the same relationship between apparent volume of distribution and drug binding as that proposed by Gillette (1971) based on a simple distribution model." | 1.26 | Apparent volumes of distribution and drug binding to plasma proteins and tissues. ( Gibaldi, M; McNamara, PJ, 1978) |
| " If this clearance does not change during hepatic disease, no dosage alterations for tolbutamide and other comparable drugs are necessary to maintain a constant concentration of unbound drug." | 1.26 | Influence of acute viral hepatitis on disposition and plasma binding of tolbutamide. ( Blaschke, TF; Meffin, PJ; Melmon, KL; Rowland, M; Williams, RL, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gibaldi, M | 1 |
| McNamara, PJ | 1 |
| Williams, RL | 1 |
| Blaschke, TF | 1 |
| Meffin, PJ | 1 |
| Melmon, KL | 1 |
| Rowland, M | 1 |
2 other studies available for tolbutamide and Viral Hepatitis, Human
| Article | Year |
|---|---|
Apparent volumes of distribution and drug binding to plasma proteins and tissues.
Topics: Blood Proteins; Hepatitis, Viral, Human; Humans; Models, Biological; Pharmaceutical Preparations; Pr | 1978 |
Influence of acute viral hepatitis on disposition and plasma binding of tolbutamide.
Topics: Acute Disease; Adult; Bilirubin; Blood Proteins; Half-Life; Hepatitis, Viral, Human; Humans; Injecti | 1977 |