tolbutamide has been researched along with Ventricular Fibrillation in 2 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 7.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 3.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, LR | 1 |
| Collins, JE | 1 |
| Krop, S | 1 |
| Zhang, HL | 1 |
| Li, YS | 1 |
| Fu, SX | 1 |
| Yang, XP | 1 |
2 other studies available for tolbutamide and Ventricular Fibrillation
| Article | Year |
|---|---|
Effects of prolonged tolbutamide treatment on plasma glucose concentrations and isoproterenol-induced cardiac lesions in rats.
Topics: Animals; Blood Glucose; Body Weight; Drug Interactions; Female; Heart Diseases; Isoproterenol; Male; | 1977 |
Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; Hyp | 1991 |