Page last updated: 2024-11-05

tolbutamide and Thalassemia

tolbutamide has been researched along with Thalassemia in 1 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.

Research Excerpts

ExcerptRelevanceReference
"To investigate the development of diabetes mellitus in patients with thalassemia major, plasma glucose and immunoreactive insulin (IRI) levels following oral glucose and intravenous tolbutamide and glucose disappearance rates following intravenous insulin were measured in 10 patients before and during five years on a high transfusion program (HTP)."3.65Carbohydrate metabolism and pancreatic islet-cell function in thalassemia major. ( Costin, G; Hyman, C; Kogut, MD; Ortega, JA, 1977)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Costin, G1
Kogut, MD1
Hyman, C1
Ortega, JA1

Other Studies

1 other study available for tolbutamide and Thalassemia

ArticleYear
Carbohydrate metabolism and pancreatic islet-cell function in thalassemia major.
    Diabetes, 1977, Volume: 26, Issue:3

    Topics: Adolescent; Child; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenou

1977