tolbutamide has been researched along with Reperfusion Injury in 2 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to study the effects of nicorandil (an ATP-sensitive K+ channel opener) and tolbutamide (an ATP-sensitive K+ channel blocker) on reperfusion-induced arrhythmias in pentobarbitone and ketamine anesthetized rabbits." | 7.71 | Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| "The aim was to study the effects of nicorandil (an ATP-sensitive K+ channel opener) and tolbutamide (an ATP-sensitive K+ channel blocker) on reperfusion-induced arrhythmias in pentobarbitone and ketamine anesthetized rabbits." | 3.71 | Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q | 1 |
| Liu, Y | 1 |
| Jiao, J | 1 |
| Zhang, C | 1 |
| Lou, J | 1 |
| Das, B | 1 |
| Sarkar, C | 1 |
| Karanth, KS | 1 |
2 other studies available for tolbutamide and Reperfusion Injury
| Article | Year |
|---|---|
Assessment of effects of IR and IPC on activities of cytochrome P450 isozymes in rats by a five-drug cocktail approach.
Topics: Animals; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactio | 2014 |
Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; | 2001 |