tolbutamide has been researched along with Porphyria in 5 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SCHLESINGER, FG | 1 |
| Streda, M | 1 |
| Wada, O | 1 |
| Yano, Y | 1 |
| Urata, G | 1 |
| Nakao, K | 1 |
| De Matteis, F | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria[NCT03906214] | 60 participants (Actual) | Observational | 2019-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for tolbutamide and Porphyria
| Article | Year |
|---|---|
Glucose tolerance tests in the clinical picture of chronic liver diseases.
Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Body Weight | 1975 |
Toxic hepatic porphyrias.
Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyc | 1968 |
Disturbances of liver porphyrin metabolism caused by drugs.
Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; H | 1967 |
2 other studies available for tolbutamide and Porphyria
| Article | Year |
|---|---|
Possible aggravation of abdominal symptoms by tolbutamide in a patient with diabetes and hepatic porphyria.
Topics: Diabetes Complications; Diabetes Mellitus; Humans; Porphyrias; Porphyrias, Hepatic; Tolbutamide | 1961 |
Behavior of hepatic microsomal cytochromes after treatment of mice with drugs known to disturb porphyrin metabolism in liver.
Topics: Amino Acids; Animals; Barbiturates; Chemical and Drug Induced Liver Injury; Cytochromes; Depression, | 1968 |