tolbutamide has been researched along with Parkinson Disease in 10 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BARBEAU, A | 1 |
| GIGUERE, R | 1 |
| HARDY, J | 1 |
| HELLER, GL | 1 |
| DEJONG, RN | 1 |
| MAGEE, KR | 1 |
| SCHWARTZ, JF | 1 |
| YONET, HM | 1 |
| BALLARD, HS | 1 |
| GATES, EW | 1 |
| HYMAN, I | 1 |
| CASTEX, MR | 1 |
| JERVELL, O | 1 |
| Christensen, LK | 1 |
| Skovsted, L | 1 |
| Van Woert, MH | 1 |
| Mueller, PS | 1 |
| Ambani, LM | 1 |
| Rathey, U | 1 |
| Hansen, JM | 1 |
| Kristensen, M | 1 |
1 trial available for tolbutamide and Parkinson Disease
| Article | Year |
|---|---|
Tolbutamde in the treatment of Parkinson's disease--a double blind trial.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Parkinson Disease; Tolbuta | 1965 |
9 other studies available for tolbutamide and Parkinson Disease
| Article | Year |
|---|---|
[Clinical experience with tolbutamide in Parkinson's disease].
Topics: Humans; Parkinson Disease; Tolbutamide | 1961 |
Tolbutamide in the treatment of parkinsonism.
Topics: Parkinson Disease; Parkinsonian Disorders; Tolbutamide | 1961 |
Tolbutamide-induced hypoglycemia in Parkinson's disease; a case report.
Topics: Hypoglycemia; Parkinson Disease; Tolbutamide | 1961 |
Prolonged severe hypoglycemia following tolbutamide therapy for paralysis agitans.
Topics: Humans; Hypoglycemia; Pancreatic Diseases; Parkinson Disease; Tolbutamide | 1961 |
Use of tolbutamide in paralysis agitans: preliminary report.
Topics: Parkinson Disease; Tolbutamide | 1960 |
[Tolbutamide in the treatment of Parkinson's disease and multiple sclerosis].
Topics: Humans; Multiple Sclerosis; Parkinson Disease; Psychotherapy, Multiple; Tolbutamide | 1961 |
[Tolbutamide in nondiabetic diseases].
Topics: Acne Vulgaris; Angina Pectoris; Intermittent Claudication; Liver Cirrhosis; Multiple Sclerosis; Park | 1962 |
Inhibition of drug metabolism by chloramphenicol.
Topics: Aged; Biotransformation; Carbon Isotopes; Chloramphenicol; Chromatography, Thin Layer; Dicumarol; Hu | 1969 |
Abnormal insulin secretion in Parkinson's disease before and during L-dihydroxyphenylalanine (L-dopa) therapy.
Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insu | 1973 |