tolbutamide has been researched along with Paralysis in 2 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of itraconazole, a triazole antifungal agent, on cytochrome P450 were investigated by measuring the anti-convulsant activity of phenytoin in mice, and zoxazolamine paralysis time, tolbutamide clearance, and plasma dicoumarol concentrations after a single injection of dicoumarol, in rats." | 3.67 | In-vivo effects of itraconazole on hepatic mixed-function oxidase. ( Damanhouri, Z; Gumbleton, M; Nicholls, PJ; Shaw, MA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Damanhouri, Z | 1 |
| Gumbleton, M | 1 |
| Nicholls, PJ | 1 |
| Shaw, MA | 1 |
| Spuler, A | 1 |
| Lehmann-Horn, F | 1 |
| Grafe, P | 1 |
2 other studies available for tolbutamide and Paralysis
| Article | Year |
|---|---|
In-vivo effects of itraconazole on hepatic mixed-function oxidase.
Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dicumarol; Female; Itraconazole; Ketoconaz | 1988 |
Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres.
Topics: Barium; Benzopyrans; Cromakalim; Humans; Hyperkalemia; In Vitro Techniques; Membrane Potentials; Mus | 1989 |