tolbutamide has been researched along with Obesity in 183 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alterations in the production of or the sensitivity to leptin, the protein encoded by the ob gene, cause obesity and diabetes in rodents." | 7.69 | Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. ( Klein, S; Landt, M; Segal, KR, 1996) |
| "The plasma glucose and insulin responses to intravenous administration of tolbutamide in patients with insulinoma and healthy control subjects were compared to determine the sensitivity and specificity of the intravenous tolbutamide test for the diagnosis of insulinoma." | 7.67 | Diagnostic interpretation of the intravenous tolbutamide test for insulinoma. ( McMahon, MM; O'Brien, PC; Service, FJ, 1989) |
| "We have studied the effects of starvation and of obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system in fed and 3- and 5-day fasted Holtzman rats and in obese (fa/fa) and lean (Fa/?) Zucker rats." | 7.66 | Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. ( Baile, CA; Boden, G; Matschinsky, FM; McLaughlin, CL, 1981) |
| "Insulin sensitivity was increased by pioglitazone hydrochloride (P = 0." | 5.29 | Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. ( Baum, ST; Bergman, RN; Elson, DF; Kemnitz, JW; Meglasson, MD; Roecker, EB, 1994) |
| " Whereas body weight and glucose homeostasis remained the same in SF-1(ΔIR) mice as in controls under a normal chow diet, they were protected from diet-induced leptin resistance, weight gain, adiposity and impaired glucose tolerance." | 3.77 | High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. ( Belgardt, BF; Brüning, JC; Dhillon, H; Elmquist, JK; Hampel, B; Hess, S; Horvath, TL; Husch, A; Klöckener, T; Kloppenburg, P; Lowell, BB; Paeger, L; Sohn, JW; Verhagen, LA; Williams, KW; Zigman, JM, 2011) |
| "Alterations in the production of or the sensitivity to leptin, the protein encoded by the ob gene, cause obesity and diabetes in rodents." | 3.69 | Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. ( Klein, S; Landt, M; Segal, KR, 1996) |
| "In high degree obesity there a significantly smaller area under the curve of C-peptide after stimulation with Tolbutamide and significantly lower insulin sensitivity measured in vivo by euglycemic hyperinsulinemic clamp-technique (Biostator) than in moderate obesity." | 3.68 | [High-degree obesity--a risk factor for the development of diabetes mellitus]. ( Borisova, AM; Kirilov, G; Koev, D, 1990) |
| "The plasma glucose and insulin responses to intravenous administration of tolbutamide in patients with insulinoma and healthy control subjects were compared to determine the sensitivity and specificity of the intravenous tolbutamide test for the diagnosis of insulinoma." | 3.67 | Diagnostic interpretation of the intravenous tolbutamide test for insulinoma. ( McMahon, MM; O'Brien, PC; Service, FJ, 1989) |
| "We have studied the effects of starvation and of obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system in fed and 3- and 5-day fasted Holtzman rats and in obese (fa/fa) and lean (Fa/?) Zucker rats." | 3.66 | Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. ( Baile, CA; Boden, G; Matschinsky, FM; McLaughlin, CL, 1981) |
| "The effects of starvation and refeeding and of obesity on pancreatic alpha2- and beta-cell responses to glucose or tolbutamide were studied with the isolated rat or mouse pancreas perfused with an amino acid mixture in the presence and absence of glucose." | 3.66 | Adaptations of alpha2- and beta-cells of rat and mouse pancreatic islets to starvation, to refeeding after starvation, and to obesity. ( Matschinsky, FM; Norfleet, WT; Pagliara, A; Rujanavech, C, 1980) |
| "To elucidate the mechanism for growth following surgery in children with craniopharyngioma, serum somatomedin and prolactin levels, and plasma insulin (IRI) levels in response to oral glucose and intravenous tolbutamide, were determined in 5 and 8 children, respectively, at variable intervals following removal of the tumor." | 3.65 | Craniopharyngioma: the role of insulin in promoting postoperative growth. ( Costin, G; Daughaday, WH; Kogut, MD; Phillips, LS, 1976) |
| "Leptin and insulin have been identified as fuel sensors acting in part through their hypothalamic receptors to inhibit food intake and stimulate energy expenditure." | 1.33 | Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. ( Alber, J; Ashcroft, FM; Balthasar, N; Belgardt, BF; Brüning, JC; Burdakov, D; Coppari, R; Fekete, C; Hampel, B; Horvath, TL; Janoschek, R; Koch, L; Krone, W; Ma, X; Mak, TW; Münzberg, H; Plum, L; Rother, E; Schwenk, F; Seibler, J; Shanabrough, M; Suzuki, A, 2006) |
| "Insulin sensitivity was increased by pioglitazone hydrochloride (P = 0." | 1.29 | Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. ( Baum, ST; Bergman, RN; Elson, DF; Kemnitz, JW; Meglasson, MD; Roecker, EB, 1994) |
| " In three experiments the energy balance and glucose regulatory responses of Zucker obese and lean rats to chronic administration of nalmefene, an opiate antagonist, were measured." | 1.27 | Influence of nalmefene on energy balance and glucose regulation in Zucker rats. ( Baile, CA; Gingerich, RL; McLaughlin, CL; Michel, ME, 1986) |
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 169 (92.35) | 18.7374 |
| 1990's | 8 (4.37) | 18.2507 |
| 2000's | 4 (2.19) | 29.6817 |
| 2010's | 2 (1.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, HT | 1 |
| Chang, CK | 1 |
| Tsao, CW | 1 |
| Wen, YJ | 1 |
| Ling, SM | 1 |
| Cheng, KC | 1 |
| Chang, CJ | 1 |
| Cheng, JT | 1 |
| Matsui, K | 1 |
| Oda, T | 1 |
| Nishizawa, E | 1 |
| Sano, R | 1 |
| Yamamoto, H | 1 |
| Fukuda, S | 1 |
| Sasase, T | 1 |
| Miyajima, K | 1 |
| Ueda, N | 1 |
| Ishii, Y | 1 |
| Ohta, T | 1 |
| Matsushita, M | 1 |
| Vanzela, EC | 1 |
| Ribeiro, RA | 1 |
| de Oliveira, CA | 1 |
| Rodrigues, FB | 1 |
| Bonfleur, ML | 1 |
| Carneiro, EM | 1 |
| Souza, KL | 1 |
| Boschero, AC | 1 |
| Klöckener, T | 1 |
| Hess, S | 1 |
| Belgardt, BF | 2 |
| Paeger, L | 1 |
| Verhagen, LA | 1 |
| Husch, A | 1 |
| Sohn, JW | 1 |
| Hampel, B | 2 |
| Dhillon, H | 1 |
| Zigman, JM | 1 |
| Lowell, BB | 1 |
| Williams, KW | 1 |
| Elmquist, JK | 1 |
| Horvath, TL | 2 |
| Kloppenburg, P | 1 |
| Brüning, JC | 2 |
| FINEBERG, SK | 2 |
| SEFTEL, HC | 2 |
| KEELEY, KJ | 1 |
| SCHWARTZ, W | 1 |
| ROYER, P | 1 |
| MOSS, JM | 1 |
| DELAWTER, DE | 1 |
| GALLAGHER, EJ | 1 |
| BLACK, KO | 1 |
| BIRNSTINGL, MA | 1 |
| BERNHARD, H | 1 |
| SCHWARTZ, MJ | 1 |
| MIRSKY, S | 1 |
| SCHAEFER, LE | 1 |
| BOTTERMANN, P | 3 |
| SCHWARZ, K | 3 |
| KOPETZ, K | 3 |
| SDROBICI, D | 1 |
| PIEPTEA, R | 1 |
| MIHALACHE, N | 1 |
| MOROIANU, M | 1 |
| PAVEL, I | 1 |
| Plum, L | 1 |
| Ma, X | 1 |
| Balthasar, N | 1 |
| Coppari, R | 1 |
| Münzberg, H | 1 |
| Shanabrough, M | 1 |
| Burdakov, D | 1 |
| Rother, E | 1 |
| Janoschek, R | 1 |
| Alber, J | 1 |
| Koch, L | 1 |
| Seibler, J | 1 |
| Schwenk, F | 1 |
| Fekete, C | 1 |
| Suzuki, A | 1 |
| Mak, TW | 1 |
| Krone, W | 1 |
| Ashcroft, FM | 1 |
| Kreisberg, RA | 1 |
| Boshell, BR | 2 |
| DiPlacido, J | 1 |
| Roddam, RF | 2 |
| Selvini, A | 1 |
| Brugi, A | 1 |
| Emanueli, A | 1 |
| Andersen, OO | 1 |
| Friis, T | 1 |
| Cerasi, E | 1 |
| Luft, R | 1 |
| Boden, G | 1 |
| Baile, CA | 2 |
| McLaughlin, CL | 2 |
| Matschinsky, FM | 2 |
| Ziegelasch, HJ | 1 |
| Ziegelasch, H | 1 |
| Mauve, L | 1 |
| Cotrozzi, G | 1 |
| Matteini, M | 1 |
| Relli, P | 1 |
| Lazzari, T | 1 |
| Rujanavech, C | 1 |
| Pagliara, A | 1 |
| Norfleet, WT | 1 |
| Stanik, S | 1 |
| Marcus, R | 1 |
| Lebovitz, HE | 1 |
| Feinglos, MN | 1 |
| Reaven, GM | 1 |
| Reaven, EP | 1 |
| Karam, JH | 1 |
| Sieradzki, J | 1 |
| Clausen, JO | 1 |
| Hansen, T | 1 |
| Bjørbaek, C | 1 |
| Echwald, SM | 1 |
| Urhammer, SA | 1 |
| Rasmussen, S | 1 |
| Andersen, CB | 1 |
| Hansen, L | 1 |
| Almind, K | 1 |
| Winther, K | 1 |
| Krempf, M | 1 |
| Got, I | 1 |
| Ziegler, O | 1 |
| Blanchard, P | 1 |
| Ranganathan, S | 1 |
| Drouin, P | 1 |
| Charbonnel, B | 1 |
| Kemnitz, JW | 1 |
| Elson, DF | 1 |
| Roecker, EB | 1 |
| Baum, ST | 1 |
| Bergman, RN | 2 |
| Meglasson, MD | 1 |
| Segal, KR | 1 |
| Landt, M | 1 |
| Klein, S | 1 |
| Spanswick, D | 2 |
| Smith, MA | 2 |
| Groppi, VE | 1 |
| Logan, SD | 1 |
| Ashford, ML | 2 |
| Mirshamsi, S | 1 |
| Routh, VH | 1 |
| Haller, H | 2 |
| Hanefeld, M | 1 |
| Leonhardt, W | 1 |
| Balestreri, R | 2 |
| Bertolini, S | 1 |
| Elicio, N | 1 |
| Lufkin, EG | 1 |
| Taunton, OD | 1 |
| Stifel, FB | 1 |
| Rosensweig, NS | 1 |
| Hagler, L | 1 |
| Teplick, RS | 1 |
| Herman, RH | 1 |
| Páv, J | 1 |
| Srámková, J | 1 |
| Luccioni, R | 1 |
| Vague, P | 7 |
| Balansard, P | 1 |
| Vague, J | 5 |
| Simonin, R | 1 |
| Gérard, R | 1 |
| Pelkonen, R | 2 |
| Taskinen, MR | 1 |
| Nikkilä, EA | 2 |
| Ramahandridona, G | 4 |
| Vialettes, B | 2 |
| Raymond, JP | 1 |
| Jahnke, KA | 2 |
| Reis, HE | 2 |
| Jahnke, K | 2 |
| Searle, GL | 1 |
| Willms, B | 1 |
| Baranov, VG | 1 |
| Gasparian, EG | 1 |
| Reidenberg, MM | 2 |
| Spanár, E | 1 |
| Uhrín, P | 1 |
| Levcík, A | 1 |
| Záhradný, V | 1 |
| Syvälahti, E | 1 |
| Erkkola, R | 1 |
| Punnonen, R | 1 |
| Rauramo, L | 1 |
| Atzenhofer, K | 1 |
| Schnetz, H | 1 |
| Burman, KD | 1 |
| Vesell, ES | 1 |
| Grabner, W | 1 |
| Matzkies, F | 1 |
| Prestele, H | 1 |
| Rose, A | 1 |
| Daniel, U | 1 |
| Phillip, J | 1 |
| Fischer, K | 1 |
| Sareen, C | 1 |
| Ruvalcaba, RH | 1 |
| Kelley, VC | 1 |
| Barreca, T | 1 |
| Marcenaro, A | 1 |
| Valice, S | 1 |
| Costin, G | 2 |
| Kogut, MD | 2 |
| Phillips, LS | 1 |
| Daughaday, WH | 1 |
| Lee, A | 1 |
| Ader, M | 1 |
| Bray, GA | 1 |
| Falcone, T | 1 |
| Finegood, DT | 1 |
| Fantus, IG | 1 |
| Morris, D | 1 |
| Borisova, AM | 1 |
| Koev, D | 1 |
| Kirilov, G | 1 |
| McMahon, MM | 1 |
| O'Brien, PC | 1 |
| Service, FJ | 1 |
| Coves, MJ | 1 |
| Casanovas, A | 1 |
| Sarto, A | 1 |
| Casamitjana, R | 1 |
| Gomis, R | 1 |
| Vilardell, E | 1 |
| Gingerich, RL | 1 |
| Michel, ME | 1 |
| Yen, TT | 1 |
| Shires, R | 1 |
| Joffe, BI | 1 |
| Ionescu, E | 1 |
| Sauter, JF | 1 |
| Jeanrenaud, B | 1 |
| Miettinen, TA | 1 |
| Vesenne, MR | 1 |
| Butterfield, WJ | 1 |
| Whichelow, MJ | 2 |
| Stowers, JM | 1 |
| Haupt, E | 1 |
| Beyer, J | 1 |
| Schöffling, K | 1 |
| Täljedal, IB | 1 |
| Heine, P | 1 |
| Kewitz, H | 1 |
| Schnapperelle, U | 1 |
| Mashaly, M | 1 |
| el-Ebrashy, N | 1 |
| Higazi, AM | 1 |
| Einen, MA | 1 |
| Aziz, MT | 1 |
| Leupold, H | 1 |
| Hadnagy, C | 1 |
| Dambacher, M | 1 |
| Romani, JD | 1 |
| Boutier, M | 1 |
| Bernheim, R | 1 |
| Loo, H | 1 |
| Reyes, F | 1 |
| Albeaux-Fernet, M | 1 |
| Gajdos, A | 1 |
| Ewer, RW | 1 |
| Deiss, WP | 1 |
| Gorden, P | 2 |
| Roth, J | 2 |
| Rubay, J | 1 |
| Parmentier, J | 1 |
| Gutman, RA | 2 |
| Lazarus, NR | 2 |
| Penhos, JC | 1 |
| Fajans, S | 1 |
| Recant, L | 2 |
| Sherman, B | 1 |
| Shatney, CH | 1 |
| Grage, TB | 1 |
| Carducci Artenisio, A | 3 |
| Ragonese, F | 2 |
| Alibrando, S | 3 |
| Giardina, S | 1 |
| Corsi, V | 4 |
| Gerolami, A | 1 |
| Chiumello, G | 4 |
| Del Guercio, MJ | 3 |
| Di Natale, B | 1 |
| Devetta, M | 1 |
| Caccamo, A | 1 |
| Genuth, SM | 2 |
| Laurian, L | 1 |
| Oberman, Z | 1 |
| Harel, A | 1 |
| Cordova, T | 1 |
| Herzberg, M | 1 |
| Turtle, JR | 1 |
| Pfeiffer, EF | 4 |
| Laube, H | 1 |
| Grodsky, GM | 1 |
| Sando, H | 1 |
| Levin, S | 1 |
| Gerich, J | 1 |
| Karam, J | 1 |
| Pfeifer, EF | 1 |
| Bloom, A | 2 |
| Hausmann, L | 1 |
| Schubotz, R | 1 |
| Born, H | 1 |
| Kaffarnik, H | 1 |
| Kuniyoshi, N | 1 |
| Artenisio, AC | 1 |
| Allegra, V | 3 |
| Albanese, MC | 3 |
| Sprovieri, M | 2 |
| Caruso, A | 1 |
| Pildes, RS | 1 |
| Trautwein, H | 4 |
| Julitz, R | 4 |
| Serrano-Rios, M | 3 |
| Ramos, F | 3 |
| Vivanco, F | 3 |
| Rodriguez-Minon, JL | 3 |
| Keen, H | 1 |
| Jarrett, RJ | 1 |
| Ward, JD | 1 |
| Fuller, JH | 1 |
| Tchobroutsky, G | 1 |
| Kopf, A | 1 |
| Eschwege, E | 1 |
| Assan, R | 1 |
| Ratzmann, KP | 1 |
| Johansen, K | 1 |
| Knick, B | 4 |
| Beringer, A | 1 |
| Hrabal, I | 1 |
| Irsigler, K | 1 |
| Thaler, H | 1 |
| Hellerström, C | 1 |
| Westman, S | 1 |
| Stork, H | 1 |
| Schmidt, FH | 1 |
| Franckson, JR | 1 |
| Malaise, W | 1 |
| Arnould, Y | 1 |
| Rasio, E | 1 |
| Ooms, HA | 2 |
| Balasse, E | 1 |
| Conard, V | 1 |
| Bastenie, PA | 1 |
| Iafusco, F | 3 |
| Stoppoloni, G | 3 |
| von Hattingberg, HM | 1 |
| Gladtke, E | 1 |
| Dost, FH | 1 |
| Melani, F | 2 |
| Kipnis, DM | 3 |
| Rambert, P | 1 |
| Thervet, F | 1 |
| Jackson, WP | 1 |
| Bricker, LA | 1 |
| Mintz, DH | 1 |
| Duprey, J | 1 |
| Lubetzki, J | 1 |
| Schor, S | 1 |
| Arky, RA | 1 |
| Knopp, RH | 1 |
| Hellman, B | 1 |
| Sehlin, J | 1 |
| Töljedal, IB | 1 |
| Tomkins, AM | 1 |
| Devrim, S | 1 |
| Koniçe, M | 1 |
| Sencer, E | 1 |
| Molvalìlar, S | 1 |
| Alp, H | 1 |
| Bompiani, GD | 1 |
| Laudicina, E | 1 |
| Holtorff, J | 1 |
| Strauzenberg, E | 1 |
| Vaishnava, H | 1 |
| Raju, TR | 1 |
| Malik, GB | 1 |
| Gulati, PD | 1 |
| Constam, GR | 1 |
| Khurana, RC | 1 |
| Robin, JA | 1 |
| Jung, Y | 1 |
| Corredor, DG | 2 |
| Gonzalez, A | 1 |
| Sunder, JH | 2 |
| Danowski, TS | 2 |
| McAdams, GL | 1 |
| Navarrete, VN | 1 |
| Torres, IH | 1 |
| Castelazo Ayala, L | 1 |
| Alger, CR | 1 |
| Flores, HV | 1 |
| Sabeh, G | 1 |
| Mendelsohn, LV | 1 |
| Wasserman, RE | 1 |
| Junod, A | 1 |
| Letarte, J | 1 |
| Lambert, AE | 1 |
| Stauffacher, W | 1 |
| Loeb, H | 1 |
| Wolter, R | 1 |
| Brunet, N | 1 |
| Prando, R | 1 |
| Pagliaini, R | 1 |
| Cristofolini, MP | 1 |
| Adezati, L | 1 |
| Cristol, R | 1 |
| Cottet, J | 1 |
| Cloarec, M | 1 |
| Torri, A | 1 |
| Zandomeneghi, R | 1 |
| Sgarbi, E | 1 |
| Tassoni, P | 1 |
| Cicognani, A | 1 |
| Collina, A | 1 |
| Miano, A | 1 |
| Cacciari, E | 1 |
| Wajchenberg, BL | 1 |
| Nakasone, K | 1 |
| Pasternak, K | 1 |
| Möller, E | 1 |
| Klein, B | 1 |
| Lawecki, J | 2 |
| Rogala, H | 1 |
| Kowalski, H | 1 |
| Kuntz, E | 1 |
| Raptis, S | 1 |
| Rothenbuchner, G | 1 |
| Kalkhoff, R | 1 |
| Ferrou, C | 1 |
| Bruns, W | 1 |
| Michaelis, D | 1 |
| Wappler, E | 1 |
| Pierantoni, G | 1 |
| Pacelli, V | 1 |
| Bartelt, KM | 1 |
| Lenti, G | 1 |
| Pellegrini, A | 1 |
| Pagano, G | 1 |
| Mascia, V | 1 |
| Cirillo, R | 1 |
| Kremer, GJ | 1 |
| Lange, HJ | 2 |
| Kössling, FK | 1 |
| Grams, H | 1 |
| Rigas, AN | 1 |
| Bittles, AH | 1 |
| Hadden, DR | 1 |
| Montgomery, DA | 1 |
| Carnelutti, M | 2 |
| Bidone, G | 2 |
| Helge, H | 1 |
| Weber, B | 1 |
| Quabbe, HJ | 1 |
| Werner, E | 1 |
| Cutillo, S | 1 |
| Sgambato, S | 1 |
| Deuil, R | 1 |
| Letailleur, M | 1 |
| Hanusch, AW | 1 |
| Kaiser, G | 1 |
| Cantone, A | 1 |
| Kahn, CB | 1 |
| Soeldner, JS | 1 |
| Gleason, RE | 1 |
| Rojas, L | 1 |
| Camerini-Davalos, RA | 1 |
| Marble, A | 1 |
| Kazda, A | 1 |
| Shameti, H | 1 |
| Yamagata, S | 1 |
| Goto, Y | 1 |
| Oneda, A | 1 |
| Kikuchi, J | 1 |
| Toyota, T | 1 |
| Depieds, R | 1 |
| Codaccioni, JL | 1 |
| Boeuf, G | 1 |
| Cucurachi, L | 1 |
| Strata, A | 1 |
| Zuliani, U | 1 |
| Castello, S | 1 |
| Pieri, A | 1 |
| Maiello, M | 1 |
| Scarpelli, PT | 1 |
| Bianucci, GF | 1 |
| Sailer, S | 1 |
| Sandhofer, F | 1 |
| Braunsteiner, H | 1 |
| Schless, GL | 1 |
| Duncan, GG | 2 |
| Heckmann, K | 1 |
| Gardoni, L | 1 |
| Perley, M | 1 |
| Duncan, TG | 1 |
20 reviews available for tolbutamide and Obesity
| Article | Year |
|---|---|
Effects of age on various aspects of glucose and insulin metabolism.
Topics: Adolescent; Adult; Aged; Aging; Animals; Blood Glucose; Child; Diabetes Mellitus; Female; Glucose; G | 1980 |
The use of isotope turnover techniques in the study of carbohydrate metabolism in man.
Topics: Acromegaly; Alanine; Blood Glucose; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Ethano | 1976 |
[Early diagnosis and prevention of Diabetes mellitus].
Topics: Austria; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; England; Female; Germany, East | 1975 |
Oral treatment in diabetes.
Topics: Acetohexamide; Acidosis; Administration, Oral; Animals; Biguanides; Cardiovascular Diseases; Chlorpr | 1972 |
Recent developments in the management of diabetes mellitus.
Topics: Animals; Australia; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathie | 1974 |
[Insulin secretion in the clinical stages of diabetes (with glucose tolerance test abnormalities)].
Topics: Blood Glucose; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insu | 1972 |
Obesity and diabetes mellitus.
Topics: Adipose Tissue; Age Factors; Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Complication | 1974 |
Synthesis and secretion of insulin in dynamic perfusion systems.
Topics: Animals; Antimetabolites; Arginine; Carbon Radioisotopes; Computers; Glucagon; Glucose; Insulin; Ins | 1974 |
Obesity, islet function and diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diet, Reducing; Dietary Carbohydr | 1974 |
[Current problems of fatty liver].
Topics: Alcoholism; Diabetes Complications; Fatty Liver; Humans; Liver; Obesity; Tolbutamide | 1968 |
[Developmental, clinical and metabolical aspects of functional obesity childhood].
Topics: Body Weight; Carbohydrate Metabolism; Child; Chromatography, Gas; Diagnosis, Differential; Epinephri | 1968 |
[The differential diagnosis of pathological carbohydrate tolerance].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diagnosis, Differential; Fast | 1970 |
[Current pathophysiological and clinical aspects of the mode of action of blood glucose lowering sulfonamides].
Topics: Age Factors; Animals; Blood Glucose; Cattle; Diabetes Mellitus; Glucose; Glucose Tolerance Test; His | 1969 |
[Critical considerations regarding the obesity-hyperinsulinism concept].
Topics: Animals; Blood Glucose; Glucagon; Glucocorticoids; Glucose; Glucose Tolerance Test; Growth Hormone; | 1968 |
Insulin secretion in normal and diabetic individuals.
Topics: Adolescent; Amino Acids; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose; | 1970 |
[The intravenous tolbutamide test].
Topics: Adolescent; Adult; Age Factors; Aged; Carbohydrate Metabolism; Child; Child, Preschool; Diabetes Mel | 1968 |
Oral sulphonylureas in the management of diabetes.
Topics: Acetohexamide; Chlorpropamide; Cyclohexanes; Diabetes Mellitus; Endocrine Glands; Glucose Tolerance | 1971 |
Insulin-independent diabetes mellitus.
Topics: Acetohexamide; Adult; Age Factors; Aged; Basement Membrane; Capillaries; Carbohydrate Metabolism, In | 1971 |
[Blood insulin and diabetes. I. Method of study--normal subjects--diabetic disease].
Topics: Cortisone; Diabetes Mellitus; Dietary Proteins; Gastrointestinal Hormones; Glucagon; Glucose Toleran | 1971 |
Evaluation of islet-cell function in man.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Child; Diabetes Mellitus; Fasting; Glucagon; Glucose | 1971 |
10 trials available for tolbutamide and Obesity
| Article | Year |
|---|---|
The intravenous tolbutamide test in diagnosing mild and latent diabetes mellitus.
Topics: Aged; Blood Glucose; Cortisone; Diabetes Mellitus; Glucose Tolerance Test; Humans; Injections, Intra | 1967 |
Minimal model for determination of insulin sensitivity: repeatability in control and obese subjects.
Topics: Adult; Blood Glucose; Body Mass Index; Computer Simulation; Female; Glucose Tolerance Test; Humans; | 1994 |
Effect of diet, sulphonylureas, and phenformin on peripheral glucose uptake in diabetes and obesity.
Topics: Adult; Aged; Blood Flow Velocity; Body Weight; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Fema | 1968 |
[The influence of various sulphonylurea derivatives on the oral glucose-tolerance tests in healthy subjects and obese and maturity-onset diabetics (author's transl)].
Topics: Administration, Oral; Adult; Blood Glucose; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Glyb | 1974 |
Dose-response relationships of tolbutamide and glibenclamide in diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Colorimetry; Diabetes Mellitus; Dose-Response | 1974 |
Changes in serum cortisol, glucose and free fatty acid levels during tolbutamide-induced hypoglycemia in obese women.
Topics: Adolescent; Adult; Blood Glucose; Body Weight; Clinical Trials as Topic; Fatty Acids, Nonesterified; | 1972 |
Borderline diabetics and their response to tolbutamide.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diab | 1973 |
The effect of tolbutamide on the diabetic fatty liver.
Topics: Aged; Clinical Trials as Topic; Diabetes Mellitus; Fatty Liver; Female; Humans; Male; Methods; Middl | 1968 |
The University Group Diabetes Program. A statistician looks at the mortality results.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diet, Diabetic; Electrocardiog | 1971 |
Circadian variation of glucose, insulin, and free fatty acids during long-term use of oral hypoglycaemic agents in diabetes mellitus.
Topics: Aged; Blood Glucose; Chlorpropamide; Circadian Rhythm; Diabetes Mellitus; Diet, Diabetic; Fatty Acid | 1968 |
153 other studies available for tolbutamide and Obesity
| Article | Year |
|---|---|
Insulin resistance without obesity induced by cotton pellet granuloma in mice.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blood Glucose; Chemokines; Cotton Fiber; Dise | 2009 |
Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Topics: Animals; Arginine; Benzoates; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibi | 2009 |
Pregnancy restores insulin secretion from pancreatic islets in cafeteria diet-induced obese rats.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Calcium Channels; Diet; DNA; Female; Gene Expression; | 2010 |
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Blood Glucose; Body Weight; Calorimetry; | 2011 |
THE TREATMENT OF DIABETES WITH ORAL DRUGS AND DIET.
Topics: Chlorpropamide; Diabetes Mellitus; Diet; Diet, Reducing; Obesity; Phenformin; Phenmetrazine; Tolbuta | 1963 |
STUDIES IN GLYCOSURIA AND DIABETES IN NON-WHITE POPULATIONS OF THE TRANSVAAL. I. AFRICANS.
Topics: Black People; Chlorpropamide; Diabetes Mellitus; Diet; Glycosuria; Health Surveys; Hemochromatosis; | 1963 |
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates; | 1964 |
[DIABETES MELLITUS IN THE WILLI-PRADER SYNDROME].
Topics: Adolescent; Child; Congenital Abnormalities; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dwarfism; | 1963 |
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN.
Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete | 1964 |
INSULINOMA WITH SYMPTOMS FOR THIRTY YEARS.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Geriatrics; Glucose Tolerance Test; Humans; Hypoglycemi | 1964 |
LONG-TERM OBSERVATIONS ON ORAL HYPOGLYCEMIC AGENTS IN DIABETES; THE EFFECT OF CARBUTAMIDE AND TOLBUTAMIDE.
Topics: Biguanides; Biomedical Research; Carbutamide; Diabetes Mellitus; Diet; Diet Therapy; Diseases in Twi | 1965 |
PHENFORMIN, SERUM LIPIDS AND DIABETES MELLITUS.
Topics: Blood Glucose; Cholesterol; Diabetes Mellitus; Drug Therapy; Glycerides; Humans; Insulin; Lipids; Ob | 1965 |
[ON THE BEHAVIOR OF THE INSULIN-LIKE ACTIVITY OF THE BLOOD SERUM IN ADIPOSITY].
Topics: Adiposity; Cushing Syndrome; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hyperinsulinism; Ins | 1965 |
[RESEARCH ON CARBOHYDRATE METABOLISM IN COMMON GENERALIZED OBESITY].
Topics: Carbohydrate Metabolism; Glucose Tolerance Test; Obesity; Pharmacology; Tolbutamide | 1965 |
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Topics: Animals; Chromones; Diet; Eating; Female; Hypoglycemic Agents; Hypothalamus; Insulin; Leptin; Male; | 2006 |
Insulin secretion in obesity.
Topics: Diabetes Complications; Glucose Tolerance Test; Humans; Insulin; Obesity; Tolbutamide | 1967 |
[On the use of ER 102 in the treatment of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Diabetes Mellitus; Female; Humans; Insulin; Liver Cirrhosis; Male; Metformi | 1967 |
"What is inherited--what is added" hypothesis for the pathogenesis of diabetes mellitus.
Topics: Acromegaly; Adult; Carbon Isotopes; Computers, Analog; Diabetes Mellitus; Female; Glucose; Glucose T | 1967 |
Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system.
Topics: Amino Acids; Animals; Fasting; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; | 1981 |
[Incidence of pathological ECG findings, hypertension and obesity in diabetic patients depending on their mode of therapy].
Topics: Cardiomegaly; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Electrocardiograph | 1981 |
[Hyperinsulinism and insulin resistance diagnosed by oral and intravenous glucose loading and by the tolbutamide test in polycystic ovary syndrome].
Topics: Adolescent; Adult; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin Resistance; Obes | 1983 |
Adaptations of alpha2- and beta-cells of rat and mouse pancreatic islets to starvation, to refeeding after starvation, and to obesity.
Topics: Adaptation, Physiological; Animals; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerh | 1980 |
Insulin secretion improves following dietary control of plasma glucose in severely hyperglycemic obese patients.
Topics: Aged; Blood Glucose; Energy Intake; Female; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secreti | 1980 |
Therapy of insulin-independent diabetes mellitus: general considerations.
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance | 1980 |
Diabetes mellitus: therapeutic guidelines based on a functional classification.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Male; Midd | 1980 |
[Use of the determination of serum insulin in evaluating carbohydrate intolerance in obesity].
Topics: Adult; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Mal | 1981 |
Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.
Topics: Adolescent; Adult; Codon; Dexamethasone; Female; Glucose Tolerance Test; Heterozygote; Humans; Insul | 1995 |
Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Eating; Fasting; Feeding Behavior; Female; Gluc | 1994 |
Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men.
Topics: Adult; Analysis of Variance; Animals; Blood Glucose; Glucose Tolerance Test; Humans; Insulin; Insuli | 1996 |
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Cell Membrane; Electrophysiology; Glucose; Hypoglycemic Agents; Hyp | 1997 |
Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats.
Topics: Adenosine Triphosphate; Animals; Arcuate Nucleus of Hypothalamus; Glucose; Hypothalamus; In Vitro Te | 2000 |
[Modern treatment of diabetes mellitus with sulfonylurea compounds].
Topics: Cholesterol; Diabetes Mellitus; Female; Humans; Hyperlipoproteinemias; Hypoglycemia; Male; Obesity; | 1979 |
[Study of the action of tolbutamide on the hypothalamo-hypophyseal-adrenocortical system in normal and obese subjects].
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Blood Glucose; | 1975 |
Effects of insulin, tolbutamide, and glucagon on activities of jejunal carbohydrate-metabolizing enzymes in humans.
Topics: Adolescent; Adult; Carbohydrate Metabolism; Fructose-Bisphosphatase; Fructose-Bisphosphate Aldolase; | 1975 |
[A new beta cell efficiency test in the islands of Langerhans].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Humans; Ins | 1977 |
[Abnormalities of insulin secretion in coronary patients. Apropos of 67 cases].
Topics: Adult; Age Factors; Aged; Coronary Disease; Female; Glucose Tolerance Test; Humans; Hyperglycemia; H | 1977 |
Response of plasma insulin to small doses of tolbutamide in obesity and acromegaly.
Topics: Acromegaly; Blood Glucose; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Insulin; | 1977 |
Defective acute insulin secretion in diabetics. Differences between normal weight and obese subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Middle Aged; Obesity; Tolbutamide | 1978 |
[Assessment of the B-cell function in diabetic patients by means of the determination of insulin secretion following glucose-tolbutamide stimulation].
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Insulin | 1976 |
[A method of studying insulin secretion in humans: the glucose stimulation test, followed by tolbutamide].
Topics: Age Factors; Blood Glucose; Body Weight; Chronic Disease; Diabetes Mellitus; Dose-Response Relations | 1976 |
[The importance of serum insulin determination in the diagnosis and treatment of diabetes mellitus (author's transl)].
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Dose-Response Relationshi | 1975 |
[Treatment of patients with diabetes mellitus associated with obesity].
Topics: Adult; Diabetes Mellitus; Humans; Insulin; Middle Aged; Obesity; Tolbutamide | 1977 |
Obesity and fasting--effects on drug metabolism and drug action in man.
Topics: Adult; Animals; Antipyrine; Atropine; Blood Proteins; Fasting; Female; Humans; Isoniazid; Obesity; P | 1977 |
[Pathogenetic relationships between obesity and maturity-onset diabetes].
Topics: Adult; Biguanides; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; | 1977 |
Serum growth hormone, serum immunoreactive insulin and blood glucose response to intravenous tolbutamide in postmenopausal women with and without natural oestrogen therapy.
Topics: Blood Glucose; Estrogens; Female; Growth Hormone; Humans; Injections, Intravenous; Insulin; Menopaus | 1976 |
What's new for diabetes?
Topics: Adolescent; Adult; Aged; Diabetes Mellitus; Female; Glucagon; Glycosuria; Humans; Insulin; Male; Mid | 1975 |
Unaltered metabolism of antipyrine and tolbutamide in fasting man.
Topics: Administration, Oral; Adult; Antipyrine; Fasting; Female; Half-Life; Humans; Injections, Intravenous | 1975 |
[Diurnal variation of glucose tolerance and insulin secretion in man (author's transl)].
Topics: Adolescent; Adult; Animals; Blood Glucose; Circadian Rhythm; Diabetes Mellitus; Glucose; Glucose Tol | 1975 |
Some aspects of carbohydrate metabolism in Prader-Willi syndrome.
Topics: Adolescent; Adrenal Medulla; Adult; Blood Glucose; Diabetes Mellitus; Epinephrine; Female; Glucose T | 1975 |
[Study of the behavior of plasma free fatty acids during the tolbutamide test in normal and obese subjects].
Topics: Adult; Carbohydrate Metabolism; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Obesi | 1975 |
[Proportion of low insulin responders to glucose among the offspring of maturity-onset diabetics (author's transl)].
Topics: Adolescent; Adult; Age Factors; Blood Glucose; Body Weight; Child; Diabetes Mellitus; Glucose; Human | 1975 |
[Regeneration capacity of B-cell function in obese diabetics after weight reduction (author's transl)].
Topics: Adult; Aged; Diabetes Mellitus; Diet, Reducing; Female; Glucose; Humans; Insulin; Insulin Secretion; | 1976 |
Craniopharyngioma: the role of insulin in promoting postoperative growth.
Topics: Antigens; Blood Glucose; Carbohydrate Metabolism; Child; Child, Preschool; Craniopharyngioma; Endocr | 1976 |
Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects.
Topics: Adult; Arginine; Body Mass Index; Body Weight; Circadian Rhythm; Female; Glucose Tolerance Test; Hum | 1992 |
Androgen response to endogenous insulin secretion during the frequently sampled intravenous glucose tolerance test in normal and hyperandrogenic women.
Topics: Adult; Androgens; Androstenedione; Blood Glucose; Dehydroepiandrosterone; Female; Glucose Tolerance | 1990 |
[High-degree obesity--a risk factor for the development of diabetes mellitus].
Topics: Adolescent; Adult; C-Peptide; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; In | 1990 |
Diagnostic interpretation of the intravenous tolbutamide test for insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Body Weight; Evaluation Studies as Topic; Female; Glucose Tolera | 1989 |
[Effect of tolbutamide on the activity of transglutaminase].
Topics: Adult; Humans; Insulin; Obesity; Receptor, Insulin; Tolbutamide; Transglutaminases | 1988 |
Influence of nalmefene on energy balance and glucose regulation in Zucker rats.
Topics: Administration, Oral; Animals; beta-Endorphin; Blood Glucose; Endorphins; Energy Metabolism; Feeding | 1986 |
MTP-1307, a novel antidiabetic agent, improves the glucose intolerance of viable yellow obese-diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fasting; Glucose Toleran | 1987 |
Maximal pancreatic beta-cell stimulation and the counter-regulatory hormonal responses in South African black and white obese subjects.
Topics: Adult; Black or African American; Blood Glucose; C-Peptide; Female; Glucagon; Glucose; Humans; Insul | 1985 |
Abnormal oral glucose tolerance in genetically obese (fa/fa) rats.
Topics: Age Factors; Animals; Blood Glucose; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; M | 1985 |
Carbohydrate intolerance in gonadal dysgenesis: evidence for insulin resistance and hyperglucagonemia.
Topics: Adolescent; Adult; Aging; Arginine; Blood Glucose; Body Weight; Child; Glucagon; Glucose Tolerance T | 1985 |
Plasma-insulin in coronary heart-disease: response to oral and intravenous glucose and to tolbutamide.
Topics: Adolescent; Adult; Aged; Blood; Cholesterol; Coronary Disease; Fatty Acids; Female; Glucose Toleranc | 1965 |
Uptake of glibornuride by microdissected pancreatic islets.
Topics: Animals; Biological Transport; Camphanes; Carbon Radioisotopes; Female; Glyburide; Hypoglycemic Agen | 1974 |
Oral management of uncomplicated maturity onset diabetes.
Topics: Adult; Aged; Biguanides; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Glucose Toleran | 1974 |
[Studies on the course of mass screening in discovered diabetic patients].
Topics: Adolescent; Adult; Aged; Biguanides; Child; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; Hu | 1974 |
Glyconeogenesis of old diabetics.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Egg White; Gluconeogenesis; Glucose-6-Phosphatase; Hu | 1966 |
[Determination of antibody inhibited and noninhibited serum insulin activity in obesity and the reaction following intravenous glucose administration].
Topics: Adenoma, Islet Cell; Glucose; Humans; Injections, Intravenous; Insulin; Insulin Antibodies; Obesity; | 1966 |
[Obesity and diabetic disease].
Topics: Age Factors; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hypoglycemia | 1968 |
[Some new data on the biochemistry of insulin].
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Amino Acid Sequence; Amino Acids; Animals; Chemical Phe | 1969 |
Clinical experience with human growth hormone immunoassay by a two-antibody method.
Topics: Acromegaly; Adenoma, Chromophobe; Adenoma, Islet Cell; Amenorrhea; Anorexia Nervosa; Arginine; Dwarf | 1969 |
Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Arginine; Fasting; Female; Glucose; Glucose Tole | 1969 |
[2 cases of Langerhans adenoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Islet Cell; Adult; Aged; Angiography; Celiac Ar | 1969 |
Circulating proinsulin-like material in patients with functioning insulinomas.
Topics: Adenoma, Islet Cell; Chromatography, Gel; Electrophoresis; Glucose Tolerance Test; Humans; Hypoglyce | 1971 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
Diagnostic and surgical aspects of insulinoma. A review of twenty-seven cases.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Blood Glucose; Child; Child, Preschool; D | 1974 |
[Effect of aminophylline, a phosphodiesterase inhibitor on somatotropin secretion after intravenous tolbutamide loading in obese subjects].
Topics: Adult; Aged; Aminophylline; Blood Glucose; Fatty Acids, Nonesterified; Growth Hormone; Humans; Male; | 1973 |
Insulin response to glucose and tolbutamide in "essential" versus "pancreatic" mild glucose intolerance.
Topics: Adult; Blood Glucose; Body Weight; Chronic Disease; Diabetes Mellitus; Glucose; Glucose Tolerance Te | 1974 |
B-pancreatic function in obese and diabetic children.
Topics: Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Ethylenediamines; Female; Glucagon; Gluco | 1972 |
Metabolic clearance of insulin in man.
Topics: Adolescent; Adult; Aged; Animals; Body Surface Area; Body Weight; Cattle; Diabetes Mellitus; Fasting | 1972 |
Oral therapy in diabetes.
Topics: Acetohexamide; Administration, Oral; Animals; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Evalu | 1972 |
[Carbohydrate tolerance and insulin secretion in patients with fatty liver].
Topics: Adult; Aged; Alcoholism; Antigens; Diabetes Mellitus; Fatty Liver; Female; Glucose Tolerance Test; H | 1972 |
[Changes in serum immunoreactive insulin in diabetes during the glucose tolerance and tolbutamide tests and its clinical significance].
Topics: Antigens; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hyperthyroidism; Insulin; Male; | 1972 |
[Behavior of blood levels of I.R.I. in obese persons after endovenous tolubtamide loading].
Topics: Adult; Analysis of Variance; Antigens; Blood Glucose; Diabetes Mellitus; Female; Humans; Insulin; In | 1972 |
Adult-onset diabetes mellitus in childhood.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fa | 1973 |
[Diabetic metabolism and arteriosclerosis].
Topics: Adult; Aged; Arteries; Arteriosclerosis; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopa | 1973 |
[Secretion of insulin during the first phases of diabetes. Summary of the experiments of the authors].
Topics: Acromegaly; Adolescent; Adult; Body Weight; Diabetes Mellitus; Female; Glucose Tolerance Test; Human | 1973 |
Serial postprandial plasma insulin levels in 117 subjects with and without diabetes.
Topics: Adolescent; Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus; Eating; Humans; Insulin; Middle | 1973 |
Effects of propranolol on HGH secretion after endovenous tolbutamide load in obese subjects.
Topics: Adult; Aged; Blood Glucose; Fatty Acids, Nonesterified; Growth Hormone; Humans; Middle Aged; Obesity | 1973 |
[Current views on the diagnostic problems of diabetes mellitus].
Topics: Adult; Carbohydrate Metabolism; Child; Diabetes Mellitus; Glucose Tolerance Test; Humans; Insulin; O | 1973 |
[Insulin secretion during the early stages of diabetes (results of our experience)].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin | 1973 |
A new principle for the comparison of insulin secretory responses. II. The effect of obesity on insulin secretion.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Glucose; Glucose Tolera | 1973 |
[Insulin secretion in the early stages of diabetes mellitus (author's transl)].
Topics: Acromegaly; Diabetes Mellitus; Glucose Tolerance Test; Humans; Insulin; Obesity; Prediabetic State; | 1973 |
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice].
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyp | 1969 |
Glucose kinetics in human obesity.
Topics: Adult; Blood Glucose; Carbon Isotopes; Glucose; Glucose Tolerance Test; Humans; Insulin; Kinetics; O | 1966 |
The pancreatic -cell recognition of insulin secretagogues. II. Site of action of tolbutamide.
Topics: Animals; Extracellular Space; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretio | 1971 |
Assessment of the need for continued oral therapy in diabetics.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Fe | 1972 |
Electrophoretic characterization of circulating human proinsulin and insulin.
Topics: Acrylamides; Body Weight; Chromatography, Gel; Electrophoresis; Glucose; Humans; Insulin; Obesity; P | 1972 |
Serum immunoreactive insulin response to oral glucose and intravenous sodium tolbutamide administration in relation to obesity.
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hyperinsul | 1972 |
Obesity and diabetes.
Topics: Adolescent; Adult; Amino Acids; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; H | 1972 |
[Significance of abnormal fetal developments for the detection of prediabetic state].
Topics: Birth Weight; Congenital Abnormalities; Diabetes Mellitus; Embryonic and Fetal Development; Female; | 1972 |
[Behavior of the plasmatic STH level in obese subjects following endovenous administration of tolbutamide].
Topics: Adult; Aged; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Female; Growth Hormone; Humans; Hyp | 1972 |
Hepatic glycogen studies in Indian diabetics.
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Fatty Liver; Female; Hepatomegaly; Humans | 1971 |
Is the use of sulphonylurea derivatives in the treatment of diabetes mellitus dangerous?
Topics: Adult; Aged; Autopsy; Diabetes Complications; Diabetes Mellitus; Diet Therapy; Drug Synergism; Femal | 1971 |
Hyperinsulinemia after tolbutamide in mild glucose intolerance.
Topics: Adult; Age Factors; Aged; Blood Glucose; Body Weight; Carbohydrate Metabolism, Inborn Errors; Female | 1971 |
Effects of phenformin on insulin reserve and release.
Topics: Diabetes Mellitus; Drug Tolerance; Ethanol; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin | 1968 |
Modification of response to the triamcinolone glucose tolerance test by treatment with oral hypoglycemic agents.
Topics: Abortion, Habitual; Adolescent; Adult; Blood Glucose; Congenital Abnormalities; Female; Fetal Death; | 1966 |
Enhanced postglucose hypophosphatemia during starvation therapy of obesity.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Body Weight; Depression, Chemical; Fasting; Fatty Acids, | 1969 |
[Early diagnosis of diabetes mellitus. Results of the intravenous tolbutamide test in 1048 patients].
Topics: Adult; Age Factors; Aged; Cardiovascular Diseases; Diabetes Mellitus; Female; Germany, West; Glucose | 1969 |
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Gluca | 1969 |
Study of the glycoregulation in the obese child.
Topics: Administration, Oral; Adolescent; Blood Glucose; Child; Child, Preschool; Fatty Acids; Female; Gluco | 1970 |
[Significance of the radioimmunological determination of plasmatic insulin].
Topics: Antigen-Antibody Reactions; Chromatography; Diabetes Mellitus; Electrophoresis; Glucose Tolerance Te | 1970 |
[Study of glucose regulation by an intravenous tolbutamide test in coronar insufficiency].
Topics: Adult; Age Factors; Arteriosclerosis; Blood Glucose; Body Weight; Cholesterol; Coronary Disease; Dia | 1970 |
[Obesity and diabetes. II. Tolbutamide intravenous test in obese patients].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; | 1970 |
[Aspects of blood sugar regulation in obese children (behavior of blood sugar, insulin, somatotropin and cortisol in various experimental conditions)].
Topics: Administration, Oral; Blood Glucose; Child; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; | 1970 |
Effect of short-term tolbutamide treatment on insulin dynamics in newly diagnosed obese and non-obese adult diabetics.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Injections, Intrave | 1970 |
[Heart infarct and subclinical diabetes].
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Female; Humans; Hyperte | 1970 |
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; | 1970 |
[Classification and clinical picture of diabetes mellitus].
Topics: Age Factors; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropat | 1970 |
[Progress in the therapy of diabetes].
Topics: Adrenal Cortex Hormones; Adult; Aged; Aminocaproates; Animals; Biguanides; Blood Glucose; Child; Dia | 1971 |
Metabolic differences between obese overweight and muscular overweight men.
Topics: Adipose Tissue; Adult; Body Composition; Body Weight; Glucose Tolerance Test; Growth Hormone; Humans | 1971 |
[Diabetes mellitus. XII. Oral diabetes therapy].
Topics: Administration, Oral; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycem | 1971 |
[Myocardial infarct, diabetic metabolism and lipid value].
Topics: Adult; Aged; Blood Glucose; Cholesterol; Diabetes Complications; Diabetes Mellitus; Diagnosis, Diffe | 1967 |
[Levels of basal insulinemia and changes of the plasmatic concentration of nonesterified fatty acids (NEFA) and of blood sugar after administration of tolbutamide in obese children].
Topics: Blood Glucose; Child; Child, Preschool; Fatty Acids, Nonesterified; Humans; Insulin; Obesity; Tolbut | 1967 |
[Immunologically measurable insulin(IMI) in normal, obese and obese, diabetic subjects after intravenous administration of glucose, tolbutamide and glucagon].
Topics: Diabetes Mellitus; Glucagon; Humans; Injections, Intravenous; Insulin; Iodine Radioisotopes; Obesity | 1967 |
[The dynamics of insulinemia in man after administration of tolbutamide].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Insulin; Mid | 1968 |
[Early diabetic metabolism anomalies and bioptically objectified degree of fatty degeneration of the liver in biliary calculi patients].
Topics: Adult; Aged; Biopsy; Blood Glucose; Body Weight; Cholelithiasis; Cholesterol; Diabetes Complications | 1968 |
Combinations of oral hypoglycemic drugs in obese, insulin-resistant diabetics.
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Drug Synergi | 1968 |
[Study of the beta-pancreatic activity in essential obesity of children].
Topics: Child; Diet Therapy; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Male; Obesity; Pancre | 1968 |
Insulin secretion in diabetes mellitus.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; | 1968 |
[Obesity, arteriosclerosis and diabetes mellitus. Clinical indices for nutritional pathological mechanisms of civilization diseases].
Topics: Arteriosclerosis; Carbohydrate Metabolism; Diabetes Mellitus; Humans; Insulin; Nutritional Physiolog | 1968 |
[Tolbutamide test in adipose children: Relation between insulin, TSH, glucose and free fatty acids].
Topics: Adolescent; Child; Fatty Acids; Female; Glucose; Humans; Hyperinsulinism; Male; Obesity; Prediabetic | 1968 |
[Peculiarities of the insulin response following tolbutamide stimulation in obese children].
Topics: Child; Child, Preschool; Humans; Insulin; Obesity; Tolbutamide | 1968 |
[Diagnosis of latent diabetes in adults].
Topics: Adult; Diabetes Mellitus; Fatty Acids; Fatty Liver; Glucose Tolerance Test; Humans; Obesity; Prediab | 1968 |
[Studies of latent diabetes mellitus].
Topics: Adult; Aged; Blood Glucose; Cortisone; Diabetes Mellitus; Diagnosis, Differential; Female; Glucose; | 1969 |
[Studies on the function of pancreatic-beta in the essential obesity in children].
Topics: Child; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Obesity; Pancreas; Tolbutamide | 1969 |
Studies on factors which increase peripheral glucose uptake in man.
Topics: Diabetes Mellitus; Exercise Therapy; Glucose; Humans; Hypoglycemic Agents; Obesity; Phenformin; Tolb | 1969 |
Clinical and chemical diabetes in offspring of diabetic couples.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Complications; Diabetes Mellitus; Female; Glucose | 1969 |
[Blood glucose curves and peroral tolbutamide tests in the obese].
Topics: Adult; Blood Glucose; Cholesterol; Female; Glucose Tolerance Test; Humans; Male; Middle Aged; Obesit | 1969 |
Clinical evaluation of the effect of glyclopyramide in diabetes mellitus.
Topics: Adult; Age Factors; Aged; Animals; Blood Glucose; Carbohydrates; Chlorpropamide; Cholesterol; Diabet | 1969 |
[Variations of insulinemia and glycemia compared in the course of an intravenous tolbutamide test in 29 persons].
Topics: Blood; Blood Glucose; Diabetes Mellitus; Humans; Injections, Intravenous; Insulin; Obesity; Tolbutam | 1965 |
[Metabolic aspects of essential obesity. Effect of tolbutamide in the process of plasmatic clarification].
Topics: Adolescent; Adult; Child; Female; Humans; In Vitro Techniques; Lipids; Middle Aged; Obesity; Tolbuta | 1965 |
[Significance and value of the blood sugar curve after administration of tolbutamide in female obesity].
Topics: Diabetes Complications; Female; Glucose Tolerance Test; Humans; Obesity; Tolbutamide | 1965 |
[Studies on the behavior of insulin activity and of the metabolites of fat metabolism in the serum in adiposis].
Topics: Fatty Acids; Glucose; Humans; Insulin; Obesity; Tolbutamide | 1965 |
Overweight and triglyceride level in normal persons and patients with diabetes mellitus.
Topics: Body Weight; Diabetes Mellitus; Glycerides; Humans; Insulin; Lipids; Obesity; Tolbutamide; Triglycer | 1966 |
The beneficial effect of intermittent total fasts on the glucose tolerance in obese diabetic patients.
Topics: Blood; Diabetes Mellitus; Fasting; Glucose Tolerance Test; Humans; Ketone Bodies; Obesity; Tolbutami | 1966 |
Effects of prolonged fasting on insulin secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Female; G | 1966 |
Correlation between latent diabetes mellitus, obesity and fatty liver.
Topics: Adult; Aged; Diabetes Complications; Fatty Liver; Humans; In Vitro Techniques; Middle Aged; Obesity; | 1966 |
[The tolbutamide test in essential childhood obesity].
Topics: Blood Glucose; Child; Child, Preschool; Humans; In Vitro Techniques; Obesity; Tolbutamide | 1966 |
[Early diagnosis of diabetes mellitus by means of the tolbutamide test, especially in adipose, hypertensive and cardiovascular patients].
Topics: Diabetes Mellitus; Humans; Hypertension; Myocardial Infarction; Obesity; Tolbutamide | 1966 |
Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects.
Topics: Dexamethasone; Diabetes Mellitus; Fasting; Glucose; Humans; Injections, Intravenous; Insulin; Obesit | 1966 |
Standards of diabetic control.
Topics: Acetohexamide; Adult; Aged; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Female; Human | 1966 |