tolbutamide has been researched along with Nephrotic Syndrome in 7 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The extent and nature of furosemide (F) binding to human albumin (HA) and to the plasma of 6 children with nephrotic syndrome were studied by equilibrium dialysis at 37 degrees C and pH 7." | 3.65 | Furosemide binding to human albumin and plasma of nephrotic children. ( Prandota, J; Pruitt, AW, 1975) |
| " The purpose of the study was to investigate the pharmacokinetic of four probe drugs in adriamycin (ADR)-induced nephropathy rat." | 1.40 | Pharmacokinetic of four probe drugs in adriamycin-induced nephropathy rat. ( Chen, WH; Chen, ZB; Hu, LF; Li, D; Lin, FY; Yu, XG; Zhi, AY, 2014) |
| "The nephrotic syndrome was associated with a smaller secretion of insulin in response to intravenous glucose and tolbutamide than occurred in normals." | 1.25 | Insulin and growth hormone secretion in the nephrotic syndrome. ( Bridgman, JF; Buckler, JM; Hellman, B; Rosen, SM; Summerskill, J, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, ZB | 1 |
| Zhi, AY | 1 |
| Lin, FY | 1 |
| Li, D | 1 |
| Yu, XG | 1 |
| Chen, WH | 1 |
| Hu, LF | 1 |
| Prandota, J | 1 |
| Pruitt, AW | 1 |
| Bridgman, JF | 1 |
| Summerskill, J | 1 |
| Buckler, JM | 1 |
| Hellman, B | 1 |
| Rosen, SM | 1 |
| Kuniyoshi, N | 1 |
| Kleinknecht, D | 1 |
| Laudat, MH | 1 |
| Strauch, G | 1 |
| Jungers, P | 1 |
| Laudat, P | 1 |
| Spitz, IM | 1 |
| Rubenstein, AH | 1 |
| Bersohn, I | 1 |
| Abrahams, C | 1 |
| Lowy, C | 1 |
| Strauss, FG | 1 |
| Argy, WP | 1 |
| Schreiner, GE | 1 |
7 other studies available for tolbutamide and Nephrotic Syndrome
| Article | Year |
|---|---|
Pharmacokinetic of four probe drugs in adriamycin-induced nephropathy rat.
Topics: Animals; Bupropion; Cytochrome P-450 Enzyme System; Doxorubicin; Male; Nephrotic Syndrome; Omeprazol | 2014 |
Furosemide binding to human albumin and plasma of nephrotic children.
Topics: Acetazolamide; Aspirin; Child; Diazoxide; Dose-Response Relationship, Drug; Female; Furosemide; Huma | 1975 |
Insulin and growth hormone secretion in the nephrotic syndrome.
Topics: Adolescent; Adult; Child; Fasting; Fatty Acids, Nonesterified; Female; Glucose; Growth Hormone; Huma | 1975 |
[Changes in serum immunoreactive insulin in diabetes during the glucose tolerance and tolbutamide tests and its clinical significance].
Topics: Antigens; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hyperthyroidism; Insulin; Male; | 1972 |
Lipoprotein and carbohydrate disorders in nephrotic syndrome and uremia.
Topics: Adipose Tissue; Blood Glucose; Carbohydrate Metabolism; Cholesterol; Fatty Acids, Nonesterified; Fem | 1972 |
Carbohydrate metabolism in renal disease.
Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Creatinine; Fatty Acids, Nonesterified; F | 1970 |
Diabetic glomerulosclerosis in the absence of glucose intolerance.
Topics: Adult; Carbohydrate Metabolism; Cortisone; Diabetes Mellitus; Diabetic Nephropathies; Glomerular Fil | 1971 |