tolbutamide has been researched along with Neoplasms in 16 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "10 subjects with cancer who were currently receiving treatment and 10 additional subjects without cancer who were matched to the subjects with cancer based on gender and race were enrolled into the study." | 2.73 | Cytochrome P450 2C9 mediated metabolism in people with and without cancer. ( Cavallari, LH; Deyo, K; Molokie, RE; Momary, K; Neceskas, J; Patel, SR; Shord, SS; Viana, MA, 2008) |
| "Patients with cancer had increased serum concentrations of the acute-phase protein alpha 1-acid glycoprotein (AAG) and lowered serum concentration of albumin." | 1.26 | Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin. ( Jackson, PR; Tucker, GT; Woods, HF, 1982) |
| "The choice of an effective method to treat priapism is challenging because precise causes in the majority of patients have not been well defined." | 1.26 | Priapism: evolution of management in 48 patients in a 22-year series. ( Nelson, JH; Winter, CC, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Bo, S | 1 |
| Castiglione, A | 1 |
| Ghigo, E | 1 |
| Gentile, L | 1 |
| Durazzo, M | 1 |
| Cavallo-Perin, P | 1 |
| Ciccone, G | 1 |
| Shord, SS | 1 |
| Cavallari, LH | 1 |
| Viana, MA | 1 |
| Momary, K | 1 |
| Neceskas, J | 1 |
| Molokie, RE | 1 |
| Deyo, K | 1 |
| Patel, SR | 1 |
| CUNNINGHAM, GC | 1 |
| SHIMIZU, J | 2 |
| KOBAYASHI, J | 2 |
| OTA, T | 2 |
| YOSHIDA, H | 2 |
| FUJII, H | 2 |
| SAKAKIBARA, N | 2 |
| ARIMASA, S | 2 |
| BLACK, KO | 1 |
| BIRNSTINGL, MA | 1 |
| HECKER, E | 1 |
| FROMM, GA | 1 |
| NAJENSON, H | 1 |
| FARAONI, H | 1 |
| GINSBERG, DM | 1 |
| Jackson, PR | 1 |
| Tucker, GT | 1 |
| Woods, HF | 1 |
| Nelson, JH | 1 |
| Winter, CC | 1 |
| Searle, GL | 1 |
| Keen, H | 1 |
| Jarrett, RJ | 1 |
| Ward, JD | 1 |
| Fuller, JH | 1 |
| Wüstenberg, PW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective, Parallel Goups Study, Aimed to Evaluating Possible Benefits of the Treatment of New Generation Hypoglycaemic Drugs Compared to Sulphonylureas for the Tratment of Type 2 Diabetes Mellitus[NCT04272359] | 138 participants (Anticipated) | Observational [Patient Registry] | 2019-05-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for tolbutamide and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
HYPOGLYCEMIA ASSOCIATED WITH EXTRAPANCREATIC NEOPLASMS, WITH A NOTE ON OTHER UNUSUAL FORMS OF HYPOGLYCEMIA.
Topics: Adrenogenital Syndrome; Carcinoma, Hepatocellular; Drug Therapy; Glycogen Storage Disease Type I; Hu | 1964 |
HYPOGLYCEMIA ASSOCIATED WITH EXTRAPANCREATIC NEOPLASMS, WITH A NOTE ON OTHER UNUSUAL FORMS OF HYPOGLYCEMIA.
Topics: Adrenogenital Syndrome; Carcinoma, Hepatocellular; Drug Therapy; Glycogen Storage Disease Type I; Hu | 1964 |
The use of isotope turnover techniques in the study of carbohydrate metabolism in man.
Topics: Acromegaly; Alanine; Blood Glucose; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Ethano | 1976 |
The use of isotope turnover techniques in the study of carbohydrate metabolism in man.
Topics: Acromegaly; Alanine; Blood Glucose; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Ethano | 1976 |
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide | 1970 |
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide | 1970 |
2 trials available for tolbutamide and Neoplasms
| Article | Year |
|---|---|
Cytochrome P450 2C9 mediated metabolism in people with and without cancer.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; | 2008 |
Cytochrome P450 2C9 mediated metabolism in people with and without cancer.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; | 2008 |
Borderline diabetics and their response to tolbutamide.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diab | 1973 |
Borderline diabetics and their response to tolbutamide.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diab | 1973 |
10 other studies available for tolbutamide and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Mortality outcomes of different sulphonylurea drugs: the results of a 14-year cohort study of type 2 diabetic patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Confounding Factors, Epidemiol | 2013 |
Mortality outcomes of different sulphonylurea drugs: the results of a 14-year cohort study of type 2 diabetic patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Confounding Factors, Epidemiol | 2013 |
TOLBUTAMIDE TOLERANCE IN HYPOGLYCEMIC CHILDREN.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Hypoglycemic Agents; Neoplasms; Pancreatic Neoplasms; Pha | 1964 |
TOLBUTAMIDE TOLERANCE IN HYPOGLYCEMIC CHILDREN.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Hypoglycemic Agents; Neoplasms; Pancreatic Neoplasms; Pha | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancr | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancr | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancr | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancr | 1964 |
INSULINOMA WITH SYMPTOMS FOR THIRTY YEARS.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Geriatrics; Glucose Tolerance Test; Humans; Hypoglycemi | 1964 |
INSULINOMA WITH SYMPTOMS FOR THIRTY YEARS.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Geriatrics; Glucose Tolerance Test; Humans; Hypoglycemi | 1964 |
[DIAGNOSTIC VALUE OF TOLBUTAMIDE AND 1-LYSINE IN INSULAR ADENOMA OF THE PANCREAS].
Topics: Adenoma, Islet Cell; Humans; Hyperinsulinism; Hypoglycemia; Lysine; Neoplasms; Pancreatic Neoplasms; | 1964 |
[DIAGNOSTIC VALUE OF TOLBUTAMIDE AND 1-LYSINE IN INSULAR ADENOMA OF THE PANCREAS].
Topics: Adenoma, Islet Cell; Humans; Hyperinsulinism; Hypoglycemia; Lysine; Neoplasms; Pancreatic Neoplasms; | 1964 |
Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin.
Topics: Female; Humans; Lidocaine; Male; Middle Aged; Neoplasms; Orosomucoid; Pharmaceutical Preparations; P | 1982 |
Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin.
Topics: Female; Humans; Lidocaine; Male; Middle Aged; Neoplasms; Orosomucoid; Pharmaceutical Preparations; P | 1982 |
Priapism: evolution of management in 48 patients in a 22-year series.
Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Anticoagulants; Antipsychotic Agents; Child; Child, Pr | 1977 |
Priapism: evolution of management in 48 patients in a 22-year series.
Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Anticoagulants; Antipsychotic Agents; Child; Child, Pr | 1977 |
A study of the effects of hypoglycemia agents on vascular complications in patients with adult-onset diabetes. VI. Supplementary report on nonfatal events in patients treated with tolbutamide.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic | 1976 |
A study of the effects of hypoglycemia agents on vascular complications in patients with adult-onset diabetes. VI. Supplementary report on nonfatal events in patients treated with tolbutamide.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic | 1976 |