tolbutamide has been researched along with Myotonic Dystrophy in 7 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Insulin responses to tolbutamide, glucagon, arginine and leucine were determined and insulin resistance was measured with exogenous iv insulin." | 3.65 | Carbohydrate metabolism and insulin resistance in myotonia dystrophica. ( Hudson, AJ; Tevaarwerk, GJ, 1977) |
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tevaarwerk, GJ | 1 |
| Hudson, AJ | 1 |
| Collis, WJ | 1 |
| Engel, WK | 2 |
| Gorden, P | 1 |
| Sherman, B | 1 |
| Roth, J | 2 |
| Barbosa, J | 1 |
| Nuttall, FQ | 1 |
| Kennedy, W | 1 |
| Goetz, F | 1 |
| Huff, TA | 1 |
| Lebovitz, HE | 1 |
| Goden, P | 1 |
| Griggs, RC | 1 |
| Nissley, SP | 1 |
| Mendelsohn, LV | 1 |
| Friedman, LM | 1 |
| Corredor, DG | 1 |
| Sieracki, JC | 1 |
| Sabeh, G | 1 |
| Vester, JW | 1 |
| Danowski, TS | 1 |
7 other studies available for tolbutamide and Myotonic Dystrophy
| Article | Year |
|---|---|
Carbohydrate metabolism and insulin resistance in myotonia dystrophica.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; | 1977 |
Glucose metabolism in five neuromuscular disorders.
Topics: Amyotrophic Lateral Sclerosis; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Insulin; | 1968 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
Plasma insulin in patients with myotonic dystrophy and their relatives.
Topics: Adolescent; Adult; Aged; Amino Acids; Antigens; Arginine; Child; Child, Preschool; Electromyography; | 1974 |
Dynamics of insulin secretion in myotonic dystrophy.
Topics: Adult; Blood Glucose; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insuli | 1968 |
Studies of plasma insulin in myotonic dystrophy.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Child; Chromatography, Gel; Female; Glucose Tolerance Te | 1969 |
Insulin responses in myotonia dystrophica.
Topics: Adult; Blood Glucose; Body Weight; Depression, Chemical; Female; Glucagon; Glucose; Glucose Toleranc | 1969 |