tolbutamide has been researched along with Leanness in 7 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alterations in the production of or the sensitivity to leptin, the protein encoded by the ob gene, cause obesity and diabetes in rodents." | 7.69 | Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. ( Klein, S; Landt, M; Segal, KR, 1996) |
| "Alterations in the production of or the sensitivity to leptin, the protein encoded by the ob gene, cause obesity and diabetes in rodents." | 3.69 | Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. ( Klein, S; Landt, M; Segal, KR, 1996) |
| "Normal-weight and underweight cancer patients had a 32% to 44% reduction in insulin sensitivity (P < ." | 1.30 | Insulin secretion, glucose production, and insulin sensitivity in underweight and normal-weight volunteers, and in underweight and normal-weight cancer patients: a Clinical Research Center study. ( Abemayor, E; Manglik, S; Tayek, JA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Segal, KR | 1 |
| Landt, M | 1 |
| Klein, S | 1 |
| Tayek, JA | 1 |
| Manglik, S | 1 |
| Abemayor, E | 1 |
| Spanswick, D | 1 |
| Smith, MA | 1 |
| Mirshamsi, S | 1 |
| Routh, VH | 1 |
| Ashford, ML | 1 |
| Bedoya, FJ | 1 |
| Jeanrenaud, B | 1 |
| Gorden, P | 1 |
| Roth, J | 1 |
| Hoenig, J | 1 |
| Gittleson, NL | 1 |
| Lewis, T | 1 |
| Schmidt, H | 1 |
| Koch, M | 1 |
| Büchel, CG | 1 |
1 trial available for tolbutamide and Leanness
| Article | Year |
|---|---|
[Effect of tolbutamide on body weight of underweight patients in double blind experiments].
Topics: Body Weight; Humans; Thinness; Tolbutamide | 1969 |
6 other studies available for tolbutamide and Leanness
| Article | Year |
|---|---|
Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men.
Topics: Adult; Analysis of Variance; Animals; Blood Glucose; Glucose Tolerance Test; Humans; Insulin; Insuli | 1996 |
Insulin secretion, glucose production, and insulin sensitivity in underweight and normal-weight volunteers, and in underweight and normal-weight cancer patients: a Clinical Research Center study.
Topics: Anthropometry; Blood Glucose; Body Weight; Glucose Tolerance Test; Head and Neck Neoplasms; Humans; | 1997 |
Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats.
Topics: Adenosine Triphosphate; Animals; Arcuate Nucleus of Hypothalamus; Glucose; Hypothalamus; In Vitro Te | 2000 |
Insulin secretory response to secretagogues by perifused islets from chronically glucose-infused rats.
Topics: Animals; Colforsin; Glucose; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion | 1991 |
Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Arginine; Fasting; Female; Glucose; Glucose Tole | 1969 |
Tolbutamide for weight gaining in psychiatric patients.
Topics: Antisocial Personality Disorder; Epilepsy; Feeding and Eating Disorders; Female; Humans; Insulin; Ma | 1965 |