tolbutamide has been researched along with Kidney Failure, Chronic in 21 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia." | 7.65 | Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972) |
| "Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment." | 7.65 | Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971) |
| "Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia." | 3.65 | Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972) |
| "Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment." | 3.65 | Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971) |
| "A Tolbutamide test was done and blood sugar (BS), serum C-peptide (CP) were measured at 0, 20 and 60 minutes, as well as the plasma L-carnitine level before and after treatment." | 2.71 | L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response. ( Assenova, B; Borissova, AM; Kirilov, G; Krivoshiev, S; Tchetirska, M; Vazelov, E, 2003) |
| "Pseudouridine (psi) is an outstanding nucleoside which is not rebuilt into the tRNA once the parent tRNA is broken down." | 1.29 | Inhibition of glucose utilization in isolated rat soleus muscle by pseudouridine: implications for renal failure. ( Dzúrik, R; Lajdová, I; Spustová, V, 1993) |
| "The origin of this hypoglycemia is not clear but is probably multifactorial." | 1.26 | [Spontaneous hypoglycemia and chronic kidney insufficiency]. ( Caron, C; Langlois, M; Nawar, T; Robert, G, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vazelov, E | 1 |
| Borissova, AM | 1 |
| Kirilov, G | 1 |
| Assenova, B | 1 |
| Tchetirska, M | 1 |
| Krivoshiev, S | 1 |
| Cerletty, JM | 1 |
| Engbring, NH | 1 |
| Balant, L | 1 |
| Bures, J | 1 |
| Fixa, B | 1 |
| Kaut, V | 1 |
| Herout, V | 1 |
| Hrncír, Z | 1 |
| Dzúrik, R | 1 |
| Spustová, V | 1 |
| Lajdová, I | 1 |
| Ramirez, G | 1 |
| O'Neill, WM | 1 |
| Bloomer, HA | 1 |
| Jubiz, W | 1 |
| Langlois, M | 1 |
| Robert, G | 1 |
| Nawar, T | 1 |
| Caron, C | 1 |
| García-Ramos, JL | 1 |
| Piñón, F | 1 |
| Bolufer, P | 1 |
| Pérez-García, A | 1 |
| Frizzell, M | 1 |
| Larsen, PR | 1 |
| Field, JB | 1 |
| Kokot, F | 1 |
| Kuska, J | 1 |
| Ianhez, LE | 1 |
| Sabbaga, E | 1 |
| Spitz, I | 1 |
| Rubenstein, AH | 2 |
| Bersohn, I | 2 |
| Lawrence, AM | 1 |
| Kirsteins, L | 1 |
| Pohl, JE | 2 |
| Thurston, H | 2 |
| Davis, D | 1 |
| Morgan, MY | 1 |
| Kleinknecht, D | 1 |
| Laudat, MH | 1 |
| Strauch, G | 1 |
| Jungers, P | 1 |
| Laudat, P | 1 |
| Berger, W | 2 |
| Spitz, IM | 1 |
| Abrahams, C | 1 |
| Lowy, C | 1 |
| Spring, P | 1 |
| Willms, B | 1 |
| Quellhorst, E | 1 |
| Scheler, F | 1 |
| Redaelli, B | 1 |
| Salvadeo, A | 1 |
| Imbasciati, E | 1 |
| Ponticelli, C | 1 |
| Carneiro de Moura, M | 1 |
| Ginestal Cruz, A | 1 |
1 review available for tolbutamide and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Hepatic clearance of drugs in kidney failure].
Topics: Adrenergic beta-Antagonists; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Liver; Metabolic | 1983 |
1 trial available for tolbutamide and Kidney Failure, Chronic
| Article | Year |
|---|---|
L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response.
Topics: Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Carnitine; Drug Administration Schedule; D | 2003 |
19 other studies available for tolbutamide and Kidney Failure, Chronic
| Article | Year |
|---|---|
Azotemia and glucose intolerance.
Topics: Adult; Aged; Blood Glucose; Blood Urea Nitrogen; Creatine; Fasting; Female; Glucagon; Glucose; Gluco | 1967 |
[Severe hypoglycemia due to Dirastan (tolbutamide) in a diabetic with chronic renal failure].
Topics: Aged; Diabetes Mellitus; Diabetic Nephropathies; Female; Humans; Hypoglycemia; Kidney Failure, Chron | 1982 |
Inhibition of glucose utilization in isolated rat soleus muscle by pseudouridine: implications for renal failure.
Topics: Animals; Calcium; Diltiazem; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Kidney Failu | 1993 |
Abnormalities in the regulation of growth hormone in chronic renal failure.
Topics: Adult; Blood Glucose; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Hypothalamus; Insuli | 1978 |
[Spontaneous hypoglycemia and chronic kidney insufficiency].
Topics: Adult; Alanine; Female; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Kidney Fail | 1978 |
[Glycaemic response to intravenous tolbutamide in renal insufficiency (author's transl)].
Topics: Blood Glucose; Creatinine; Humans; Injections, Intravenous; Kidney Failure, Chronic; Tolbutamide; Ur | 1974 |
Spontaneous hypoglycemia associated with chronic renal failure.
Topics: Adult; Aged; Blood Glucose; Dextropropoxyphene; Female; Glucagon; Glucose; Glucose Tolerance Test; H | 1973 |
[Insulin secretion in chronic kidney failure].
Topics: Adolescent; Adult; Aged; Blood Glucose; Fatty Acids, Nonesterified; Female; Glomerulonephritis; Gluc | 1973 |
[Changes of carbohydrate metabolism in uremia. Effect of renal transplantation].
Topics: Adolescent; Adult; Carbohydrate Metabolism; Female; Glucose Tolerance Test; Humans; Insulin; Kidney | 1969 |
The effect of dialysis on the carbohydrate intolerance of chronic renal failure.
Topics: Adult; Blood; Blood Glucose; Carbon Dioxide; Depression, Chemical; Drug Tolerance; Fatty Acids, None | 1970 |
Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy.
Topics: Acute Disease; Administration, Oral; Adult; Albuminuria; Blood Glucose; Diazoxide; Female; Furosemid | 1972 |
Lipoprotein and carbohydrate disorders in nephrotic syndrome and uremia.
Topics: Adipose Tissue; Blood Glucose; Carbohydrate Metabolism; Cholesterol; Fatty Acids, Nonesterified; Fem | 1972 |
Use of diazoxide in hypertension with renal failure.
Topics: Adolescent; Adult; Blood Glucose; Creatine; Diazoxide; Dietary Proteins; Female; Humans; Hyperglycem | 1971 |
[88 severe incidents of hypoglycemia in patients under treatment with sulfonylurea compounds. Results of a survey throughout Switzerland during 1968 and 1969].
Topics: Age Factors; Cerebrovascular Disorders; Chlorpropamide; Diabetes Mellitus; Diagnosis, Differential; | 1971 |
Carbohydrate metabolism in renal disease.
Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Creatinine; Fatty Acids, Nonesterified; F | 1970 |
[Changes of pharmacokinetics of oral antidiabetics from drug interference and renal insufficiency].
Topics: Acetohexamide; Carbutamide; Chlorpropamide; Drug Incompatibility; Humans; Hypoglycemia; Hypoglycemic | 1970 |
[Glucose tolerance in kidney insufficiency with and without dialysis treatment].
Topics: Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Kidney Failure, Chronic; Peritonea | 1967 |
[Aspects of carbohydrate metabolism in chronic uremic patients treated with periodic hemodialysis: determination of phosphoremia during some dynamic tests].
Topics: Blood Glucose; Carbohydrate Metabolism; Glucagon; Glucose Tolerance Test; Humans; Insulin; Kidney Fa | 1967 |
Carbohydrate metabolism studies in cirrhosis of the liver.
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Female; Glucagon; Gluco | 1968 |