tolbutamide has been researched along with Ischemia in 7 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 7.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| "As a model of ischemia, pericyte-containing microvessels freshly isolated from the adult rat retina were exposed to the inhibitors of ATP synthesis, iodoacetate and antimycin A." | 3.71 | Platelet-derived growth factor-BB: a survival factor for the retinal microvasculature during periods of metabolic compromise. ( Kawamura, H; Kodama, T; Oku, H; Puro, DG; Sakagami, K, 2001) |
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 3.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gasser, R | 1 |
| Klein, W | 1 |
| Kickenweiz, E | 1 |
| Engbersen, R | 1 |
| Moons, MM | 1 |
| Wouterse, AC | 1 |
| Dijkman, HB | 1 |
| Kramers, C | 1 |
| Smits, P | 1 |
| Russel, FG | 1 |
| Kodama, T | 1 |
| Oku, H | 1 |
| Kawamura, H | 1 |
| Sakagami, K | 1 |
| Puro, DG | 1 |
| Zhang, HL | 1 |
| Li, YS | 1 |
| Fu, SX | 1 |
| Yang, XP | 1 |
| Ghilchik, MW | 1 |
| Morris, AS | 1 |
| Krzanowski, JJ | 1 |
| Fertel, R | 1 |
| Matschinsky, FM | 1 |
| Binder, PS | 1 |
| Heiskell, CA | 1 |
| Adams, JR | 1 |
| Cerra, FB | 1 |
| Eilert, JB | 1 |
| Bergan, JJ | 1 |
7 other studies available for tolbutamide and Ischemia
| Article | Year |
|---|---|
Vasodilative response to hypoxia and simulated ischemia is mediated by ATP-sensitive K+ channels in guinea pig thoracic aorta.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Deoxyglucose; Guinea Pigs; In Vitro Techniques; Is | 1993 |
Sulphonylurea drugs reduce hypoxic damage in the isolated perfused rat kidney.
Topics: Analysis of Variance; Animals; ATP-Binding Cassette Transporters; Glyburide; Hypoglycemic Agents; In | 2000 |
Platelet-derived growth factor-BB: a survival factor for the retinal microvasculature during periods of metabolic compromise.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Becaplermin; Capillaries; Cell Survival; Iodoacetates; | 2001 |
Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; Hyp | 1991 |
Abnormal insulin response in patients with small-vessel disease.
Topics: Diabetic Angiopathies; Diagnosis, Differential; Female; Foot; Glucose Tolerance Test; Humans; Insuli | 1971 |
Energy metabolism in pancreatic islets of rats. Studies with tolbutamide and hypoxia.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Glucose; Glycogen; Hypoxia; Insulin; Insulin Secreti | 1971 |
Pancreatic function after normothermic ischemia. I. In vivo ischemia.
Topics: Amylases; Animals; Blood Glucose; Body Temperature; Disease Models, Animal; Dogs; Drug Tolerance; Fe | 1970 |