tolbutamide has been researched along with Insulin Sensitivity in 97 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Stevioside, a glycoside contained in the leaves of Stevia rebaudiana Bertoni (Compositae), was used to screen the effect induced by a diet containing 60% fructose on insulin resistance in rats." | 7.73 | Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats. ( Chang, JC; Cheng, JT; Liu, IM; Wu, MC, 2005) |
| "Alterations in the production of or the sensitivity to leptin, the protein encoded by the ob gene, cause obesity and diabetes in rodents." | 7.69 | Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. ( Klein, S; Landt, M; Segal, KR, 1996) |
| "Insulin sensitivity was increased by pioglitazone hydrochloride (P = 0." | 5.29 | Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. ( Baum, ST; Bergman, RN; Elson, DF; Kemnitz, JW; Meglasson, MD; Roecker, EB, 1994) |
| " Stevioside, a glycoside contained in the leaves of Stevia rebaudiana Bertoni (Compositae), was used to screen the effect induced by a diet containing 60% fructose on insulin resistance in rats." | 3.73 | Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats. ( Chang, JC; Cheng, JT; Liu, IM; Wu, MC, 2005) |
| " Effects of SCFA on insulin sensitivity (SI), glucose effectiveness (SG), KG and baseline concentrations of glucose, insulin, glucagon and free fatty acids were examined in unfed 20-50 kg pigs (n = 6)." | 3.69 | Splanchnic infusions of short chain fatty acids do not change insulin sensitivity of pigs. ( Apps, KV; Finegood, DT; McBurney, MI, 1995) |
| "The role of insulin resistance in the impaired glucose-stimulated insulin release of Zucker fatty rats was investigated using the insulin-sensitizing thiazolidinedione drug pioglitazone." | 3.69 | Insulin secretory defect in Zucker fa/fa rats is improved by ameliorating insulin resistance. ( de Souza, CJ; Meglasson, MD; Robinson, DD; Ulrich, RG; Yu, JH, 1995) |
| "Alterations in the production of or the sensitivity to leptin, the protein encoded by the ob gene, cause obesity and diabetes in rodents." | 3.69 | Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. ( Klein, S; Landt, M; Segal, KR, 1996) |
| "The effect of the method of insulin administration on insulin sensitivity estimates from the insulin modified minimal model (MINMOD) protocol was evaluated using the tolbutamide-boosted protocol as a reference." | 3.69 | Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol. ( Bergman, RN; Boyadjian, R; Jinagouda, SD; Khan, A; Riad-Gabriel, M; Saad, MF; Sharma, A; Steil, GM, 1997) |
| "Insulin tolerance test was done to assess the insulin sensitivity in a group of untreated non insulin dependent diabetic subjects before and after sulfonylurea (tolbutamide, glibenclamide, glipizide) therapy." | 3.68 | Effect of sulphonylurea therapy on insulin sensitivity in non insulin dependent diabetics. ( Dash, RJ; Khandekar, S; Sethi, BK, 1990) |
| "In high degree obesity there a significantly smaller area under the curve of C-peptide after stimulation with Tolbutamide and significantly lower insulin sensitivity measured in vivo by euglycemic hyperinsulinemic clamp-technique (Biostator) than in moderate obesity." | 3.68 | [High-degree obesity--a risk factor for the development of diabetes mellitus]. ( Borisova, AM; Kirilov, G; Koev, D, 1990) |
| "Carbohydrate metabolism was studied in a group of 66 women, taking cyproterone acetate (CA) and ethinyloestradiol (EO) as anti-androgen therapy for the treatment of hirsutism and/or acne." | 3.67 | The effects of cyproterone acetate and ethinyl oestradiol on carbohydrate metabolism. ( Godsland, IF; Jacobs, HS; Seed, M; Wynn, V, 1984) |
| "In order to elucidate the mechanism of the glucose intolerance frequently associated with myotonic dystrophy (MD), glucose metabolism of 10 patients and 10 controls was investigated using the following tests: successive intravenous stimulation of insulin secretion by glucose and tolbutamide, detection of serum islet cell antibodies, measure of the specific insulin binding on erythrocytes and evaluation in vivo of insulin sensitivity by the euglycaemic glucose clamp method." | 3.67 | Mechanism and significance of insulin resistance in myotonic dystrophy. ( Moulin, JP; Pouget, J; Serratrice, G; Vague, P; Vialettes, B; Viard, R, 1986) |
| " Insulin responses to tolbutamide, glucagon, arginine and leucine were determined and insulin resistance was measured with exogenous iv insulin." | 3.65 | Carbohydrate metabolism and insulin resistance in myotonia dystrophica. ( Hudson, AJ; Tevaarwerk, GJ, 1977) |
| "A Tolbutamide test was done and blood sugar (BS), serum C-peptide (CP) were measured at 0, 20 and 60 minutes, as well as the plasma L-carnitine level before and after treatment." | 2.71 | L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response. ( Assenova, B; Borissova, AM; Kirilov, G; Krivoshiev, S; Tchetirska, M; Vazelov, E, 2003) |
| "The search for the genetic basis of NIDDM has magnified the need for an efficient representation of the pre-NIDDM phenotype." | 2.39 | Toward an integrated phenotype in pre-NIDDM. ( Ader, M; Bergman, RN; Rebrin, K; Steil, G; Watanabe, R, 1996) |
| "Maturity-onset diabetes of the young (MODY) is a form of non-insulin-dependent diabetes mellitus (NIDDM) associated with autosomal-dominant inheritance." | 1.29 | Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree. ( Bell, GI; Fajans, SS; Halter, JB; Herman, WH; Ortiz, FJ; Polonsky, KS; Smith, MJ; Sturis, J, 1994) |
| "Insulin sensitivity was increased by pioglitazone hydrochloride (P = 0." | 1.29 | Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. ( Baum, ST; Bergman, RN; Elson, DF; Kemnitz, JW; Meglasson, MD; Roecker, EB, 1994) |
| "Pseudouridine (psi) is an outstanding nucleoside which is not rebuilt into the tRNA once the parent tRNA is broken down." | 1.29 | Inhibition of glucose utilization in isolated rat soleus muscle by pseudouridine: implications for renal failure. ( Dzúrik, R; Lajdová, I; Spustová, V, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (60.82) | 18.7374 |
| 1990's | 23 (23.71) | 18.2507 |
| 2000's | 13 (13.40) | 29.6817 |
| 2010's | 2 (2.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jellyman, JK | 1 |
| Valenzuela, OA | 1 |
| Allen, VL | 1 |
| Holdstock, NB | 1 |
| Fowden, AL | 1 |
| Wu, HT | 1 |
| Chang, CK | 1 |
| Tsao, CW | 1 |
| Wen, YJ | 1 |
| Ling, SM | 1 |
| Cheng, KC | 1 |
| Chang, CJ | 1 |
| Cheng, JT | 8 |
| Miyazaki, M | 1 |
| Fujii, T | 1 |
| Takeda, N | 1 |
| Magotani, H | 1 |
| Iwanaga, K | 1 |
| Kakemi, M | 1 |
| Liu, IM | 7 |
| Hsu, CF | 1 |
| Vazelov, E | 1 |
| Borissova, AM | 1 |
| Kirilov, G | 3 |
| Assenova, B | 1 |
| Tchetirska, M | 1 |
| Krivoshiev, S | 1 |
| MARIGO, S | 2 |
| PANELLI, G | 2 |
| SEGRE, EJ | 1 |
| BARRETT, JC | 1 |
| BOSHELL, BR | 2 |
| KODEJSZKO, E | 1 |
| RUVALCABA, RH | 1 |
| SAMOLS, E | 1 |
| KELLEY, VC | 1 |
| SCHNEIDER, HJ | 1 |
| KALKHOFF, R | 1 |
| SCHALCH, DS | 2 |
| WALKER, JL | 1 |
| BECK, P | 1 |
| KIPNIS, DM | 1 |
| DAUGHADAY, WH | 1 |
| HAWKINS, RD | 1 |
| CRAWFORD, AL | 1 |
| HAIST, RE | 1 |
| Carbunaru, G | 1 |
| Prasad, P | 1 |
| Scoccia, B | 1 |
| Shea, P | 1 |
| Hopwood, N | 1 |
| Ziai, F | 1 |
| Chang, YT | 1 |
| Myers, SE | 1 |
| Mason, JI | 1 |
| Pang, S | 1 |
| Zhao, YF | 1 |
| Zhu, YL | 1 |
| Chen, C | 1 |
| Bruns, CM | 1 |
| Baum, ST | 3 |
| Colman, RJ | 1 |
| Eisner, JR | 1 |
| Kemnitz, JW | 3 |
| Weindruch, R | 2 |
| Abbott, DH | 1 |
| Gordillo-Moscoso, A | 1 |
| Valadéz-Castillo, JF | 1 |
| Mandeville, PB | 1 |
| Hernández-Sierra, JF | 1 |
| Liu, TP | 2 |
| Lee, CS | 1 |
| Liou, SS | 1 |
| Chang, JC | 1 |
| Wu, MC | 1 |
| Chen, CC | 1 |
| Hsu, JH | 1 |
| Wu, YC | 1 |
| Kronfeld, DS | 1 |
| Raggi, F | 1 |
| Frumin, AM | 1 |
| Seed, M | 1 |
| Godsland, IF | 1 |
| Wynn, V | 1 |
| Jacobs, HS | 1 |
| Holländer, E | 2 |
| Tattersall, RB | 1 |
| Cotrozzi, G | 2 |
| Matteini, M | 2 |
| Relli, P | 2 |
| Lazzari, T | 2 |
| Bufalini, GN | 1 |
| Lebovitz, HE | 2 |
| Feinglos, MN | 1 |
| McBurney, MI | 1 |
| Apps, KV | 1 |
| Finegood, DT | 2 |
| de Souza, CJ | 1 |
| Yu, JH | 1 |
| Robinson, DD | 1 |
| Ulrich, RG | 1 |
| Meglasson, MD | 2 |
| Clausen, JO | 1 |
| Hansen, T | 1 |
| Bjørbaek, C | 1 |
| Echwald, SM | 1 |
| Urhammer, SA | 1 |
| Rasmussen, S | 1 |
| Andersen, CB | 1 |
| Hansen, L | 1 |
| Almind, K | 1 |
| Winther, K | 1 |
| Krempf, M | 1 |
| Got, I | 1 |
| Ziegler, O | 1 |
| Blanchard, P | 1 |
| Ranganathan, S | 1 |
| Drouin, P | 1 |
| Charbonnel, B | 1 |
| Osei, K | 1 |
| Henry, M | 1 |
| Ferguson, R | 1 |
| Roecker, EB | 2 |
| Elson, DF | 2 |
| Bergman, RN | 5 |
| Herman, WH | 1 |
| Fajans, SS | 1 |
| Ortiz, FJ | 1 |
| Smith, MJ | 1 |
| Sturis, J | 1 |
| Bell, GI | 1 |
| Polonsky, KS | 1 |
| Halter, JB | 1 |
| Dzúrik, R | 4 |
| Spustová, V | 4 |
| Lajdová, I | 1 |
| Kruszynska, YT | 1 |
| Harry, DS | 1 |
| McIntyre, N | 1 |
| Segal, KR | 1 |
| Landt, M | 1 |
| Klein, S | 1 |
| Sebeková, K | 1 |
| Watanabe, R | 1 |
| Rebrin, K | 1 |
| Ader, M | 1 |
| Steil, G | 1 |
| Saad, MF | 1 |
| Steil, GM | 1 |
| Riad-Gabriel, M | 1 |
| Khan, A | 1 |
| Sharma, A | 1 |
| Boyadjian, R | 1 |
| Jinagouda, SD | 1 |
| Luo, J | 1 |
| Quan, J | 1 |
| Tsai, J | 1 |
| Hobensack, CK | 1 |
| Sullivan, C | 1 |
| Hector, R | 1 |
| Reaven, GM | 1 |
| Chang, SL | 1 |
| Lin, JG | 1 |
| Chi, TC | 1 |
| Viviani, GL | 1 |
| Pacini, G | 1 |
| Yaspelkis, BB | 1 |
| Davis, JR | 1 |
| Saberi, M | 1 |
| Smith, TL | 1 |
| Jazayeri, R | 1 |
| Singh, M | 1 |
| Fernandez, V | 1 |
| Trevino, B | 1 |
| Chinookoswong, N | 1 |
| Wang, J | 1 |
| Shi, ZQ | 1 |
| Levin, N | 1 |
| Huseman, C | 1 |
| Johanson, A | 1 |
| Varma, M | 1 |
| Blizzard, RM | 1 |
| Tevaarwerk, GJ | 1 |
| Hudson, AJ | 1 |
| Andreev, D | 1 |
| Turkolev, N | 1 |
| Farag, Y | 1 |
| Gaafar, MA | 1 |
| Jucci, A | 1 |
| Vignini, M | 1 |
| Pelfini, C | 1 |
| Criffŏ, A | 1 |
| Fratino, P | 1 |
| Xie, W | 1 |
| Li, A | 1 |
| Wang, S | 1 |
| Dzúriková, K | 1 |
| Khandekar, S | 1 |
| Sethi, BK | 1 |
| Dash, RJ | 1 |
| Falcone, T | 1 |
| Fantus, IG | 1 |
| Morris, D | 1 |
| Borisova, AM | 2 |
| Koev, D | 2 |
| Vialettes, B | 1 |
| Pouget, J | 1 |
| Viard, R | 1 |
| Moulin, JP | 1 |
| Serratrice, G | 1 |
| Vague, P | 2 |
| Hosokawa, T | 1 |
| Ando, K | 1 |
| Tamura, G | 1 |
| Ionescu, E | 1 |
| Sauter, JF | 1 |
| Jeanrenaud, B | 1 |
| Costin, G | 1 |
| Kogut, MD | 1 |
| Vesely, DL | 1 |
| Coleman, MJ | 1 |
| Kohler, PO | 1 |
| Jordan, RM | 1 |
| Stanley, S | 1 |
| Johansen, K | 1 |
| Lundbaek, K | 1 |
| Hed, R | 1 |
| Nygren, A | 1 |
| Sundblad, L | 1 |
| McFarlin, DE | 1 |
| Barlow, MH | 1 |
| Creutzfeldt, W | 1 |
| Frerichs, H | 1 |
| Kneer, P | 1 |
| Cerdán Vallejo, A | 1 |
| Jolin Buzo, T | 1 |
| Sánchez Franco, F | 1 |
| Ortíz Vázquez, J | 1 |
| Adlung, J | 2 |
| Koch, CD | 1 |
| Ratzmann, KP | 1 |
| Vague, J | 1 |
| Pfeifer, EF | 1 |
| Mosin, VI | 1 |
| Sensi, S | 1 |
| Moneta, E | 1 |
| Capani, F | 1 |
| Caradonna, P | 1 |
| Garcea, N | 1 |
| Carotenuto, M | 1 |
| Artenisio, AC | 2 |
| Allegra, V | 2 |
| Albanese, MC | 2 |
| Sprovieri, M | 2 |
| Alibrando, S | 2 |
| Caruso, A | 2 |
| Corsi, V | 2 |
| Koch, C | 1 |
| Ritter, U | 1 |
| Berkowitz, D | 1 |
| Kopetz, K | 2 |
| Bacon, GE | 1 |
| Parkhurst, RD | 1 |
| Kleinknecht, D | 1 |
| Laudat, MH | 1 |
| Strauch, G | 1 |
| Jungers, P | 1 |
| Laudat, P | 1 |
| Bompiani, GD | 1 |
| Laudicina, E | 1 |
| Roddam, RF | 1 |
| McAdams, GL | 1 |
| Feldman, JM | 1 |
| Kahil, ME | 1 |
| McIlhaney, GR | 1 |
| Jordan, PH | 1 |
| Mueller, PS | 1 |
| Quick, DT | 1 |
| Wehrmann, P | 1 |
| Raptis, S | 1 |
| Rothenbuchner, G | 1 |
| Pfeiffer, EF | 1 |
| Bojanowicz, K | 1 |
| Stach, A | 1 |
| Orzeszyna, S | 1 |
| Fineberg, SK | 1 |
| Hosák, L | 1 |
| Komenda, S | 1 |
| Rastogi, GK | 1 |
| Singhal, KC | 1 |
| Spellacy, WN | 1 |
| Goetz, FC | 1 |
| Greenberg, BZ | 1 |
| Schoeller, KL | 1 |
| Genuth, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Improving Insulin Sensitivity by Combined Both Electroacupuncture and Drug Therapy[NCT00379379] | 26 participants | Interventional | 2005-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for tolbutamide and Insulin Sensitivity
| Article | Year |
|---|---|
Comparison of equivalence and determination of diagnostic utility of min-mod and clamp methods for insulin resistance in diabetes free subjects: a meta-analysis.
Topics: Blood Glucose; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insu | 2004 |
[25 years of diabetic treatment by oral hypoglycemic agents: successes and failures].
Topics: Aged; Aging; Blood Glucose; Cardiovascular Diseases; Chlorpropamide; Diabetes Complications; Diabete | 1984 |
Toward an integrated phenotype in pre-NIDDM.
Topics: Animals; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucose; Glucose Clamp Technique; Gluc | 1996 |
[Pathogenesis of hepatogenic diabetes mellitus].
Topics: Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose Tolerance Test; Humans; Hyperg | 1972 |
[Insulin secretion in the clinical stages of diabetes (with glucose tolerance test abnormalities)].
Topics: Blood Glucose; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insu | 1972 |
Obesity, islet function and diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diet, Reducing; Dietary Carbohydr | 1974 |
[Carbohydrate metabolism in liver diseases].
Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucagon; Glu | 1974 |
[The pathogenesis of hepatogenic diabetes mellitus].
Topics: Animals; Blood Glucose; Diabetes Mellitus; Dogs; Fatty Acids, Nonesterified; Glucose Tolerance Test; | 1970 |
Metabolic considerations in the treatment of juvenile diabetes mellitus.
Topics: Acid-Base Equilibrium; Amino Acids; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Diab | 1969 |
5 trials available for tolbutamide and Insulin Sensitivity
| Article | Year |
|---|---|
Sex-associated differences in pancreatic β cell function in healthy preweaning pony foals.
Topics: Animals; Animals, Suckling; Blood Glucose; Female; Glucose; Horses; Hypoglycemic Agents; Insulin; In | 2014 |
L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response.
Topics: Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Carnitine; Drug Administration Schedule; D | 2003 |
Minimal model for determination of insulin sensitivity: repeatability in control and obese subjects.
Topics: Adult; Blood Glucose; Body Mass Index; Computer Simulation; Female; Glucose Tolerance Test; Humans; | 1994 |
[Pathogenesis of diabetes in adulthood. I. Insulin secretion at different evolutionary phases of diabetes].
Topics: Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Glucose Tolerance Test; Humans; I | 1978 |
Glucose tolerance, free fatty acid, and serum insulin responses in patients with cirrhosis.
Topics: Adult; Alcoholism; Blood Glucose; Clinical Trials as Topic; Fatty Acids, Nonesterified; Female; Gluc | 1969 |
83 other studies available for tolbutamide and Insulin Sensitivity
| Article | Year |
|---|---|
Insulin resistance without obesity induced by cotton pellet granuloma in mice.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Blood Glucose; Chemokines; Cotton Fiber; Dise | 2009 |
Chronopharmacological assessment identified GLUT4 as a factor responsible for the circadian variation of the hypoglycemic effect of tolbutamide in rats.
Topics: Adipocytes; Animals; Blood Glucose; Chronobiology Phenomena; Circadian Rhythm; Glucose; Glucose Tran | 2011 |
Rapid induction of insulin resistance in opioid mu-receptor knock-out mice.
Topics: Animals; Blood Glucose; Diet; Food Deprivation; Fructose; Humans; Hypoglycemic Agents; Insulin; Insu | 2003 |
[Changes in insulin sensitivity after tolbutamide therapy].
Topics: Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Tolbutamide | 1958 |
[Insulinase and its inhibition by hypoglycemic sulfonamides; data on insulin sensitivity during tolbutamide therapy].
Topics: Endopeptidases; Humans; Hydrolases; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulysin; Pep | 1958 |
Diabetes mellitus with insulin resistance: report of a case successfully treated with tolbutamide.
Topics: Diabetes Mellitus; Hypoglycemic Agents; Insulin; Insulin Resistance; Tolbutamide | 1962 |
Tolbutamide in the therapy of insulin resistance.
Topics: Insulin Antibodies; Insulin Resistance; Tolbutamide | 1962 |
[CLINICAL PROBLEMS IN THE MATTER OF INSULIN RESISTANCE].
Topics: Adolescent; Chlorpropamide; Diabetes Mellitus; Diagnosis; Drug Tolerance; Hemagglutination; Humans; | 1964 |
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Dru | 1965 |
[INSULIN RESISTANCE].
Topics: Adrenal Cortex Hormones; Anti-Allergic Agents; Diabetes Mellitus; Drug Hypersensitivity; Drug Therap | 1965 |
DIABETOGENIC FACTORS ASSOCIATED WITH PREGNANCY.
Topics: Diabetes Mellitus; Fatty Acids; Female; Glucose Tolerance Test; Growth Hormone; Hormones; Humans; In | 1964 |
THE EFFECT OF RESERPINE ON THE SENSITIVITY OF RATS TO INSULIN AND TOLBUTAMIDE.
Topics: Animals; Blood Glucose; Drug Tolerance; Fasting; Insulin; Insulin Resistance; Pancreatectomy; Pharma | 1964 |
The hormonal phenotype of Nonclassic 3 beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in hyperandrogenic females is associated with insulin-resistant polycystic ovary syndrome and is not a variant of inherited HSD3B2 deficiency.
Topics: 3-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Area Under Curve; Blood Glucose; Female; Glucose | 2004 |
[3T3-L1 adipocytes reduces Kir6.2 channel expression in MIN6 insulin-secreting cells in vitro].
Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cells, Cultured; Coculture Techniques; Gene Ex | 2004 |
Insulin resistance and impaired insulin secretion in prenatally androgenized male rhesus monkeys.
Topics: Animals; Area Under Curve; Female; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; In | 2004 |
Improvement of insulin resistance by panax ginseng in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Drugs, Chinese Herbal; Fructose; Glucose Intolerance; Glucose Tolerance Test | 2005 |
Improvement of insulin resistance by Acanthopanax senticosus root in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Eleuthe | 2005 |
Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Diterpenes, Kaurane; | 2005 |
Improvement of insulin resistance by miracle fruit (Synsepalum dulcificum) in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Dose-Respo | 2006 |
Dioscorea as the principal herb of Die-Huang-Wan, a widely used herbal mixture in China, for improvement of insulin resistance in fructose-rich chow-fed rats.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates | 2007 |
Changing activity of erythrocyte glucose-6-phosphate dehydrogenase and tolerances to glucose and tolbutamide in growing sheep.
Topics: Animals; Animals, Newborn; Drug Tolerance; Erythrocytes; Glucokinase; Glucose Tolerance Test; Glucos | 1967 |
The effects of cyproterone acetate and ethinyl oestradiol on carbohydrate metabolism.
Topics: Acne Vulgaris; Adolescent; Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Cyproterone; Cy | 1984 |
[Testing insulin and sulfonylurea sensitivity in type II diabetes mellitus].
Topics: Aged; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; | 1984 |
[Hyperinsulinism and insulin resistance diagnosed by oral and intravenous glucose loading and by the tolbutamide test in polycystic ovary syndrome].
Topics: Adolescent; Adult; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin Resistance; Obes | 1983 |
[Hyperinsulinism and insulin resistance in the polycystic ovary syndrome as tested with tolbutamide].
Topics: Adolescent; Adult; Blood Glucose; Female; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Poly | 1982 |
Therapy of insulin-independent diabetes mellitus: general considerations.
Topics: Blood Glucose; Diabetes Mellitus; Glucagon; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance | 1980 |
Splanchnic infusions of short chain fatty acids do not change insulin sensitivity of pigs.
Topics: Acetates; Acetic Acid; Animals; Blood Glucose; Butyrates; Fatty Acids, Nonesterified; Fatty Acids, V | 1995 |
Insulin secretory defect in Zucker fa/fa rats is improved by ameliorating insulin resistance.
Topics: Aging; Amino Acids; Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Hypoglycemi | 1995 |
Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.
Topics: Adolescent; Adult; Codon; Dexamethasone; Female; Glucose Tolerance Test; Heterozygote; Humans; Insul | 1995 |
Differential effects of systemic insulin delivery and prednisone on tissue glucose and insulin sensitivity in insulin-dependent diabetes mellitus pancreas recipients.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1994 |
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys.
Topics: Animals; Blood Glucose; Diet; Fasting; Glucose; Glucose Tolerance Test; Glycated Hemoglobin; Injecti | 1994 |
Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.
Topics: Adolescent; Adult; Blood Glucose; Child; Chromosomes, Human, Pair 20; Diabetes Mellitus, Type 2; Fem | 1994 |
Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Eating; Fasting; Feeding Behavior; Female; Gluc | 1994 |
Accumulated end products participate in glucose intolerance and insulin resistance in uremia.
Topics: Animals; Glucose; Glucose Intolerance; Hippurates; Humans; In Vitro Techniques; Insulin Resistance; | 1993 |
Inhibition of glucose utilization in isolated rat soleus muscle by pseudouridine: implications for renal failure.
Topics: Animals; Calcium; Diltiazem; Glucose; In Vitro Techniques; Insulin; Insulin Resistance; Kidney Failu | 1993 |
Insulin sensitivity, insulin secretion and glucose effectiveness in diabetic and non-diabetic cirrhotic patients.
Topics: Administration, Oral; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus; Glucose; Glucose Clamp Tec | 1993 |
Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men.
Topics: Adult; Analysis of Variance; Animals; Blood Glucose; Glucose Tolerance Test; Humans; Insulin; Insuli | 1996 |
Inhibition of glucose uptake by 5-hydroxyindoleacetic acid in the isolated rat soleus muscle.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Glucose; Hindlimb; Hydroxyindoleacetic Acid; Hyp | 1996 |
Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol.
Topics: Adult; Blood Glucose; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Infusions, Intravenous; I | 1997 |
Nongenetic mouse models of non-insulin-dependent diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Di | 1998 |
An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats.
Topics: Acupuncture Points; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Diabete | 1999 |
Reduced glucose effectiveness as a feature of glucose intolerance: evidence in elderly type-2 diabetic subjects.
Topics: Adult; Age Factors; Aged; Aging; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fasting; Fem | 1999 |
Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats.
Topics: 3-O-Methylglucose; Animals; Blood Glucose; Body Mass Index; Diet; Dietary Fats; Energy Intake; Gluco | 2001 |
Congenital lipodystrophy: An endocrine study in three siblings. I. Disorders of carbohydrate metabolism.
Topics: Adolescent; Adrenocorticotropic Hormone; Antigens; Arginine; Blood Glucose; Child; Child, Preschool; | 1978 |
Carbohydrate metabolism and insulin resistance in myotonia dystrophica.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Female; Fructose; | 1977 |
Insulin tolerance test and tolbutamide tolerance test in acromegaly.
Topics: Acromegaly; Adult; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Male; Middle Aged; To | 1977 |
Psoriasis and insulin secretion. Preliminary results.
Topics: Blood Glucose; Body Weight; Diabetes Mellitus; Glucose Tolerance Test; Humans; Insulin; Insulin Resi | 1977 |
The effect of tolbutamide on burn hypermetabolism.
Topics: Adult; Animals; Blood Glucose; Burns; Energy Metabolism; Female; Glucagon; Humans; Insulin; Insulin | 1992 |
[Improvement in glucose tolerance and insulin sensitivity after a single administration of tolbutamide in hypertensive patients].
Topics: Blood Glucose; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Ma | 1991 |
Effect of sulphonylurea therapy on insulin sensitivity in non insulin dependent diabetics.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Glipizide; Glyburide; Humans; Insulin Resistance; Middle A | 1990 |
Androgen response to endogenous insulin secretion during the frequently sampled intravenous glucose tolerance test in normal and hyperandrogenic women.
Topics: Adult; Androgens; Androstenedione; Blood Glucose; Dehydroepiandrosterone; Female; Glucose Tolerance | 1990 |
[High-degree obesity--a risk factor for the development of diabetes mellitus].
Topics: Adolescent; Adult; C-Peptide; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; In | 1990 |
[Combination treatment with insulin and sulfonylurea. Results of a 5-year study].
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies | 1989 |
[Factors affecting stability in the course of insulin-dependent diabetes mellitus].
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Chronic Disease; Circadian Rhythm; Diabetes Mellitus, T | 1989 |
Mechanism and significance of insulin resistance in myotonic dystrophy.
Topics: Adult; Autoantibodies; Blood Glucose; Erythrocytes; Female; Glucose Tolerance Test; Humans; Insulin; | 1986 |
An ascochlorin derivative, AS-6, reduces insulin resistance in the genetically obese diabetic mouse, db/db.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drinking; | 1985 |
Abnormal oral glucose tolerance in genetically obese (fa/fa) rats.
Topics: Age Factors; Animals; Blood Glucose; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; M | 1985 |
Carbohydrate intolerance in gonadal dysgenesis: evidence for insulin resistance and hyperglucagonemia.
Topics: Adolescent; Adult; Aging; Arginine; Blood Glucose; Body Weight; Child; Glucagon; Glucose Tolerance T | 1985 |
Hyperalimentation as cause of markedly worsened metabolic control in a patient with autoantibodies to the insulin receptor.
Topics: Acanthosis Nigricans; Adult; Autoantibodies; Blood Glucose; Cyclophosphamide; Female; Humans; Hyperg | 1985 |
Plasma-insulin in mild juvenile diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Immunoassay; Insulin; Insu | 1967 |
Insulin response in chronic alcoholism.
Topics: Alcoholism; Blood Glucose; Carbohydrate Metabolism; Glucose Tolerance Test; Humans; Hyperinsulinism; | 1968 |
An unusual form of diabetes mellitus in ataxia telangiectasia.
Topics: Adolescent; Adult; Ataxia Telangiectasia; Blood Glucose; Child; Diabetes Mellitus; Fatty Acids, None | 1970 |
Liver disease, insulin antagonism and diabetes mellitus.
Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Fatty Acids, None | 1974 |
[Hepatic cirrhosis (non hemochromatosic) Diabetes mellitus. III. Secretion of insulin in cirrhotic patients tolerant and non tolerant to oral glucose overload].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Re | 1974 |
Influence of tolbutamide on serum glucose level, specific activity of glucose and glucose oxidation in severe diabetes.
Topics: Adolescent; Adult; Aged; Blood Glucose; Carbon Dioxide; Carbon Radioisotopes; Diabetes Mellitus; Dia | 1974 |
Studies of glucose metabolism in mothers of large babies.
Topics: Adult; Birth Weight; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; | 1972 |
[Behavior of blood levels of I.R.I. in obese persons after endovenous tolubtamide loading].
Topics: Adult; Analysis of Variance; Antigens; Blood Glucose; Diabetes Mellitus; Female; Humans; Insulin; In | 1972 |
[Behavior of the serum I.R.I. in persons with latent diabetes after endovenous tolbutamide load].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Humans; Insulin; Insulin Antibodies; Insulin Resist | 1972 |
[Carbohydrate tolerance, insulin secretion and insulin sensitivity in acute pancreatitis].
Topics: Acute Disease; Adult; Aged; Blood Glucose; Female; Glucose Tolerance Test; Humans; Insulin; Insulin | 1974 |
Lipoprotein and carbohydrate disorders in nephrotic syndrome and uremia.
Topics: Adipose Tissue; Blood Glucose; Carbohydrate Metabolism; Cholesterol; Fatty Acids, Nonesterified; Fem | 1972 |
Obesity and diabetes.
Topics: Adolescent; Adult; Amino Acids; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; H | 1972 |
Effects of phenformin on insulin reserve and release.
Topics: Diabetes Mellitus; Drug Tolerance; Ethanol; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin | 1968 |
Effect of fasting on insulin secretion and action in mice.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Hydroco | 1970 |
Effect of enteric hormones on insulin secretion.
Topics: Adult; Blood Glucose; Cholecystokinin; Diabetes Mellitus; Female; Glucagon; Hormones; Humans; Hyperg | 1970 |
Studies of glucose, insulin, and lipid metabolism in amyotrophic lateral sclerosis and other neuromuscular disorders.
Topics: Adult; Amyotrophic Lateral Sclerosis; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Female | 1970 |
[Metabolic changes following glucose and tolbutamide loading in liver cirrhosis and their role in the pathogenesis of hepatogenic diabetes mellitus].
Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Fasting; Fatty Acids, Nonesterified; Gluc | 1970 |
[Progress in the therapy of diabetes].
Topics: Adrenal Cortex Hormones; Adult; Aged; Aminocaproates; Animals; Biguanides; Blood Glucose; Child; Dia | 1971 |
[Behavior of the insulin-, tolbutamide- and cortisone-tests depending on the age and body constitution of adult diabetics].
Topics: Adolescent; Adult; Age Factors; Aged; Blood Glucose; Body Constitution; Cortisone; Depression, Chemi | 1971 |
Combinations of oral hypoglycemic drugs in obese, insulin-resistant diabetics.
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Drug Synergi | 1968 |
[On the anticonvulsive effects of tolbutamide in the treatment of schizophrenia with hypoglycemic coma].
Topics: Adolescent; Adult; Aged; Convulsive Therapy; Female; Humans; Hypoglycemia; Insulin; Insulin Coma; In | 1968 |
Young insulin-refractory diabetics.
Topics: Adolescent; Adult; Age Factors; Diabetes Mellitus; Female; Humans; Insulin; Insulin Resistance; Male | 1969 |
Tolbutamide response in normal pregnancy.
Topics: Blood; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Pregnancy; Tolbutamide | 1965 |
Effects of prolonged fasting on insulin secretion.
Topics: Adult; Blood Glucose; Diabetes Mellitus; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Female; G | 1966 |