Compounds > tolbutamide
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tolbutamide and Hyperlipemia

tolbutamide has been researched along with Hyperlipemia in 33 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Halofenate is a new antilipemic drug which is an ester of carboxylic acid."2.64The metabolic spectrum of halofenate. ( Ryan, JR, 1975)
" Similar pharmacokinetic changes were observed in HL rats after oral administration of tolbutamide."1.40Pharmacokinetics of tolbutamide and its metabolite 4-hydroxy tolbutamide in poloxamer 407-induced hyperlipidemic rats. ( Cho, YY; Choi, HD; Choi, MR; Kang, HE; Kim, YC; Kwon, MH, 2014)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199032 (96.97)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, MR1
Kwon, MH1
Cho, YY1
Choi, HD1
Kim, YC1
Kang, HE1
SHIPP, JC2
MUNROE, JF1
WADDELL, WR1
HURLEY, N1
FIELD, RA1
WOOD, FC1
MARBLE, A1
KNITTLE, JL1
AHRENS, EH1
GUMPEL, RC1
SCOW, RO1
CHERNICK, SS1
BRINLEY, MS1
GEBBIE, T1
REID, JD1
WEISSEL, W1
JUUL, J1
JAKOVCIC, S1
FUHRMANN, W1
HSIA, DY1
SULLIVAN, JF1
LANKFORD, HG1
GRINNELL, EH1
DE GENNES, JL1
BOUCHON, JP1
GODEAU, P1
BETOURNE, C1
CAMUS, JP1
LEVY, R1
SIGUIER, F1
SCHIFF, BL1
SONKIN, N1
KANE, JP1
LONGCOPE, C1
PAVLATOS, FC1
GRODSKY, GM1
Kallio, IV1
Saarimaa, HA1
Ryan, JR2
Jain, AK1
McMahon, FG1
Luccioni, R1
Vague, P1
Balansard, P1
Vague, J1
Simonin, R1
Gérard, R1
Vaisrub, S1
Ceruso, D1
Frisina, N1
Nicita-Mauro, V1
Friedman, M1
Rosenman, RH1
Byers, SO1
Frank, O1
Tidl, G1
Pfeiffer, EF1
Laube, H1
Pfeifer, EF1
Debry, G1
Popescu, P1
Anghel, S1
Idu, S1
Mihai, N1
Moldovan, T1
Mihail, A1
Sauer, H1
Böninger, C1
Bricker, LA1
Mintz, DH1
Bacon, GE1
Parkhurst, RD1
Thiele, P1
Keen, H1
Nestel, PJ1

Reviews

4 reviews available for tolbutamide and Hyperlipemia

ArticleYear
Obesity and diabetes mellitus.
    Advances in metabolic disorders, 1974, Volume: 7, Issue:0

    Topics: Adipose Tissue; Age Factors; Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Complication

1974
Obesity, islet function and diabetes mellitus.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: Suppl 4

    Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diet, Reducing; Dietary Carbohydr

1974
Insulin-independent diabetes mellitus.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Acetohexamide; Adult; Age Factors; Aged; Basement Membrane; Capillaries; Carbohydrate Metabolism, In

1971
Metabolic considerations in the treatment of juvenile diabetes mellitus.
    The Medical clinics of North America, 1969, Volume: 53, Issue:6

    Topics: Acid-Base Equilibrium; Amino Acids; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Diab

1969

Trials

2 trials available for tolbutamide and Hyperlipemia

ArticleYear
The metabolic spectrum of halofenate.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Blood Glucose; Cholesterol; Clinical Trials as Topic; Clofibrate; Creatine Kinase; Glycolates; Halof

1975
Potentiation of hypoglycemic effect of sulfonylureas by halofenate.
    The New England journal of medicine, 1975, Dec-18, Volume: 293, Issue:25

    Topics: Adult; Clinical Trials as Topic; Clofibrate; Diabetes Complications; Diabetes Mellitus; Drug Synergi

1975

Other Studies

27 other studies available for tolbutamide and Hyperlipemia

ArticleYear
Pharmacokinetics of tolbutamide and its metabolite 4-hydroxy tolbutamide in poloxamer 407-induced hyperlipidemic rats.
    Biopharmaceutics & drug disposition, 2014, Volume: 35, Issue:5

    Topics: Administration, Oral; Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P450 Fami

2014
Effects of sulfonylurea compounds on hyperlipemia and hypercholesteremia in patients with minimal impairment of glucose tolerance.
    Diabetes, 1962, Volume: 11(Suppl)

    Topics: Carbohydrate Metabolism; Diabetes Mellitus; Glucose; Humans; Hypercholesterolemia; Hyperlipidemias;

1962
Treatment of "idiopathic" hyperlipemia.
    Metabolism: clinical and experimental, 1962, Volume: 11

    Topics: Hyperlipidemias; Lipids; Niacin; Nicotinic Acids; Tolbutamide

1962
HYPERLIPEMIA FOLLOWING SULFONYLUREA THERAPY IN YOUNG DIABETICS.
    JAMA, 1964, May-04, Volume: 188

    Topics: Carbohydrate Metabolism; Diabetes Mellitus; Hyperlipidemias; Retina; Sulfonylurea Compounds; Tolbuta

1964
CARBOHYDRATE METABOLISM IN TWO FORMS OF HYPERGLYCERIDEMIA.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Hyperlipidemias; Lipoprotein Lipase; Path

1964
HYPERLIPEMIA AND SULFONYLUREA THERAPY.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Diet; Diet Therapy; Humans; Hyperlipidemias; Hypoglycemic Agents; Pharmacology; Sulfonylurea Compoun

1964
HYPERLIPEMIA AND KETOSIS IN THE PREGNANT RAT.
    The American journal of physiology, 1964, Volume: 206

    Topics: Acidosis; Adipose Tissue; Animals; Blood Glucose; Body Weight; Cholesterol; Fasting; Fatty Acids; Fa

1964
EFFECT OF TOLBUTAMIDE IN CLEARING INDUCED ALIMENTARY LIPAEMIA AFTER ALCOHOLIC HEPATOPANCREATIC DAMAGE.
    Lancet (London, England), 1964, Sep-26, Volume: 2, Issue:7361

    Topics: Alcoholism; Blood Glucose; Dietary Fats; Fatty Acids; Glycerides; Hyperlipidemias; Injections, Intra

1964
[GLUCOSE TOLERANCE AND TOLBUTAMIDE EFFECT IN INCREASED SERUM CHOLESTEROL].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1964, Volume: 45

    Topics: Angina Pectoris; Carbohydrate Metabolism; Cholesterol; Glucose Tolerance Test; Hypercholesterolemia;

1964
[MASSIVE HYPERLIPEMIA AND DIABETES MELLITUS. A CASE OF HEREDITARY OCCURRENCE OF THE COMBINATION].
    Ugeskrift for laeger, 1964, Nov-05, Volume: 126

    Topics: Diabetes Mellitus; Diet, Diabetic; Drug Therapy; Genetics, Medical; Hyperlipidemias; Insulin; Pathol

1964
ESSENTIAL FAMILIAL HYPERLIPEDEMIA IN CHILDHOOD. I. CARBOHYDRATE-INDUCED HYPERLIPIDEMIA.
    Pediatrics, 1964, Volume: 34

    Topics: Adolescent; Blood; Carbohydrates; Child; Chromatography; Dietary Carbohydrates; Dietary Fats; Fatty

1964
SERUM LIPID ABNORMALITIES IN DIABETES MELLITUS.
    Current therapeutic research, clinical and experimental, 1965, Volume: 7

    Topics: Blood Glucose; Diabetes Mellitus; Diet; Fasting; Glycerides; Humans; Hyperglycemia; Hyperlipidemias;

1965
[COMPARISON OF 14 PERSONAL CASES OF HYPERLIPEMIA WITH THE CLASSICAL CONCEPTS].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1965, Jan-26, Volume: 41

    Topics: Drug Therapy; Glucagon; Heparin; Hyperlipidemias; Hyperlipoproteinemia Type I; Hyperlipoproteinemia

1965
ERUPTIVE DIABETIC XANTHOMA. SKIN DISORDER ASSOCIATED WITH DIABETES CAN BE REVERSED BY CONTROL OF HYPERLIPEMIA.
    Rhode Island medical journal, 1965, Volume: 48

    Topics: Diabetes Mellitus; Dietary Fats; Humans; Hyperlipidemias; Pathology; Skin Diseases; Tolbutamide; Xan

1965
STUDIES OF CARBOHYDRATE METABOLISM IN IDIOPATHIC HYPERTRIGLYCERIDEMIA.
    Metabolism: clinical and experimental, 1965, Volume: 14

    Topics: Adolescent; Blood Glucose; Carbohydrate Metabolism; Fatty Acids; Geriatrics; Glucose; Glucose Tolera

1965
Changes in blood lipids, postprandial lipemia and intravenous tolbutamide test response after insulin shock treatment.
    The American journal of the medical sciences, 1967, Volume: 254, Issue:5

    Topics: Adult; Blood Glucose; Convulsive Therapy; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Hum

1967
[Abnormalities of insulin secretion in coronary patients. Apropos of 67 cases].
    Archives des maladies du coeur et des vaisseaux, 1977, Volume: 70, Issue:9

    Topics: Adult; Age Factors; Aged; Coronary Disease; Female; Glucose Tolerance Test; Humans; Hyperglycemia; H

1977
Editorial: Platelet aggregation.
    JAMA, 1975, Oct-27, Volume: 234, Issue:4

    Topics: Adenosine Diphosphate; Aspirin; Cerebrovascular Disorders; Coronary Disease; Glucose; Humans; Hyperl

1975
[Clofibrate and carbohydrate metabolism: behavior of blood insulin in patients with blood lipid disorders].
    Bollettino della Societa italiana di cardiologia, 1975, Volume: 20, Issue:11

    Topics: Adult; Age Factors; Aged; Arteriosclerosis; Blood Glucose; Carbohydrate Metabolism; Clofibrate; Fema

1975
Response of hyperlipemic subjects to carbohydrates, pancreatic hormones and prolonged fasting.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:12

    Topics: Adrenocorticotropic Hormone; Adult; Fasting; Fructose; Glucagon; Glucose; Humans; Hyperlipidemias; H

1968
[The prevalence of lipid metabolism disorders in rheumatological diseases].
    Wiener medizinische Wochenschrift (1946), 1974, Sep-14, Volume: 124, Issue:37

    Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Blood Glucose; Body Weight; Cholesterol; Diabetes M

1974
[Carbohydrate metabolism in hyperlipemia].
    Annales de biologie clinique, 1973, Volume: 31, Issue:2

    Topics: Carbohydrate Metabolism; Diet; Ethanol; Female; Humans; Hypercholesterolemia; Hyperglycemia; Hyperli

1973
[On the intravenous tolbutamide test (ivTT) in patients with coronary disease. (Glucide-lipid metabolic relationships)].
    Medicina interna, 1974, Volume: 26, Issue:4

    Topics: Adult; Aged; Carbohydrate Metabolism; Coronary Disease; Diabetic Angiopathies; Female; Humans; Hyper

1974
[What is reliable in the therapy of diabetes mellitus?].
    Der Internist, 1970, Volume: 11, Issue:12

    Topics: Carbutamide; Chlorpropamide; Chronic Disease; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nep

1970
[Hyperlipemia--an accelerating factor in occlusive arterial diseases].
    Das Deutsche Gesundheitswesen, 1971, Jan-28, Volume: 26, Issue:5

    Topics: Arteriosclerosis Obliterans; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Fatty Acids

1971
Factors influencing the progress of atherosclerosis in the diabetic.
    Acta diabetologica latina, 1971, Volume: 8 Suppl 1

    Topics: Adolescent; Adult; Aged; Arteriosclerosis; Child; Diabetes Mellitus; Diabetic Angiopathies; Female;

1971
Carbohydrate-induced hypertriglyceridemia and glucose utilization in ischemic heart disease.
    Metabolism: clinical and experimental, 1966, Volume: 15, Issue:9

    Topics: Adult; Blood Glucose; Body Weight; Dietary Carbohydrates; Fatty Acids, Nonesterified; Glucose; Glyce

1966