tolbutamide has been researched along with Heart Disease, Ischemic in 6 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to study the effects of nicorandil (an ATP-sensitive K+ channel opener) and tolbutamide (an ATP-sensitive K+ channel blocker) on reperfusion-induced arrhythmias in pentobarbitone and ketamine anesthetized rabbits." | 7.71 | Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| "The aim was to study the effects of nicorandil (an ATP-sensitive K+ channel opener) and tolbutamide (an ATP-sensitive K+ channel blocker) on reperfusion-induced arrhythmias in pentobarbitone and ketamine anesthetized rabbits." | 3.71 | Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meier, JJ | 1 |
| Gallwitz, B | 1 |
| Schmidt, WE | 1 |
| Mügge, A | 1 |
| Nauck, MA | 1 |
| Nakaya, H | 1 |
| Zünkler, BJ | 1 |
| Henning, B | 1 |
| Ott, T | 1 |
| Hildebrandt, AG | 1 |
| Fleck, E | 1 |
| Knowler, WC | 1 |
| Sartor, G | 1 |
| Melander, A | 1 |
| Scherstén, B | 1 |
| Das, B | 1 |
| Sarkar, C | 1 |
| Karanth, KS | 1 |
| Vanheel, B | 1 |
| de Hemptinne, A | 1 |
2 reviews available for tolbutamide and Heart Disease, Ischemic
| Article | Year |
|---|---|
Is impairment of ischaemic preconditioning by sulfonylurea drugs clinically important?
Topics: Animals; Cardiovascular Agents; Catheterization; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Age | 2004 |
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; G | 1993 |
1 trial available for tolbutamide and Heart Disease, Ischemic
| Article | Year |
|---|---|
Glucose tolerance and mortality, including a substudy of tolbutamide treatment.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Cause of Death; Confidence I | 1997 |
3 other studies available for tolbutamide and Heart Disease, Ischemic
| Article | Year |
|---|---|
Effects of tolbutamide on ATP-sensitive K+ channels from human right atrial cardiac myocytes.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Atrial Function, Right; Benzopyrans; Child; Cromaka | 1997 |
Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; | 2001 |
Influence of KATP channel modulation on net potassium efflux from ischaemic mammalian cardiac tissue.
Topics: Action Potentials; Animals; Barium; Benzopyrans; Cromakalim; Glyburide; Guinea Pigs; Hydrogen-Ion Co | 1992 |