Page last updated: 2024-11-05

tolbutamide and Genetic Predisposition

tolbutamide has been researched along with Genetic Predisposition in 3 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Congenic strains for the two subloci (Niddm1f and Niddm1i) have been generated by transfer of GK alleles onto the genome of F344 rats."1.31Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats. ( Bergsten, P; Fakhrai-Rad, H; Galli, J; Lin, JM; Luthman, H; Ortsäter, H, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ivask, M1
Hugill, A1
Kõks, S1
Tsukada, S1
Kobayashi, MA1
Omori, S1
Unoki, H1
Maeda, S1
Lin, JM1
Ortsäter, H1
Fakhrai-Rad, H1
Galli, J1
Luthman, H1
Bergsten, P1

Other Studies

3 other studies available for tolbutamide and Genetic Predisposition

ArticleYear
RNA-sequencing of WFS1-deficient pancreatic islets.
    Physiological reports, 2016, Volume: 4, Issue:7

    Topics: Animals; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory

2016
Transcription factor AP-2beta inhibits glucose-induced insulin secretion in cultured insulin-secreting cell-line.
    Diabetes research and clinical practice, 2009, Volume: 85, Issue:3

    Topics: Animals; Cell Line; Cricetinae; Diabetes Mellitus, Type 2; DNA Primers; Genetic Predisposition to Di

2009
Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats.
    Diabetes, 2001, Volume: 50, Issue:12

    Topics: Alleles; Animals; Crosses, Genetic; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Gl

2001