tolbutamide has been researched along with Diabetic Nephropathies in 16 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FABRYKANT, M | 1 |
| GELFAND, ML | 1 |
| ROSENBERG, AS | 1 |
| Bures, J | 1 |
| Fixa, B | 1 |
| Kaut, V | 1 |
| Herout, V | 1 |
| Hrncír, Z | 1 |
| Christiansen, E | 2 |
| Tibell, A | 2 |
| Võlund, A | 1 |
| Rasmussen, K | 2 |
| Tydén, G | 2 |
| Pedersen, O | 1 |
| Christensen, NJ | 1 |
| Madsbad, S | 2 |
| Osei, K | 1 |
| Henry, M | 1 |
| Ferguson, R | 1 |
| Haslbeck, M | 1 |
| Lenti, G | 1 |
| Yamada, K | 1 |
| Abe, M | 1 |
| Yamashita, K | 1 |
| Murachi, T | 1 |
| Shimada, N | 1 |
| Tchertkoff, V | 1 |
| Nayak, SV | 1 |
| Kamath, C | 1 |
| Salomon, MI | 1 |
| Sauer, H | 1 |
| Böninger, C | 1 |
| Ziegelasch, HJ | 1 |
| Andres, R | 1 |
| Kuntz, E | 1 |
| Strauss, FG | 1 |
| Argy, WP | 1 |
| Schreiner, GE | 1 |
| Sestoft, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective, Parallel Goups Study, Aimed to Evaluating Possible Benefits of the Treatment of New Generation Hypoglycaemic Drugs Compared to Sulphonylureas for the Tratment of Type 2 Diabetes Mellitus[NCT04272359] | 138 participants (Anticipated) | Observational [Patient Registry] | 2019-05-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tolbutamide and Diabetic Nephropathies
| Article | Year |
|---|---|
[New aspects of therapy with oral antidiabetic agents].
Topics: Acidosis; Biguanides; Blood Proteins; Chlorpropamide; Diabetes Mellitus; Diabetic Nephropathies; Dru | 1979 |
1 trial available for tolbutamide and Diabetic Nephropathies
| Article | Year |
|---|---|
Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucose | 1994 |
14 other studies available for tolbutamide and Diabetic Nephropathies
| Article | Year |
|---|---|
FURTHER EXPERIENCE WITH ANABOLIC STEROIDS IN DIABETIC RETINOPATHY: FACTORS PRECIPITATING RETINAL HEMORRHAGES.
Topics: Diabetic Nephropathies; Diabetic Retinopathy; Diet, Diabetic; Drug Therapy; Estrogens; Geriatrics; H | 1964 |
[Severe hypoglycemia due to Dirastan (tolbutamide) in a diabetic with chronic renal failure].
Topics: Aged; Diabetes Mellitus; Diabetic Nephropathies; Female; Humans; Hypoglycemia; Kidney Failure, Chron | 1982 |
Differential effects of systemic insulin delivery and prednisone on tissue glucose and insulin sensitivity in insulin-dependent diabetes mellitus pancreas recipients.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1994 |
Defects in quantitative and qualitative beta-cell function following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation (DSSGMEPT).
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Fasting; | 1993 |
A study of the effects of hypoglycemia agents on vascular complications in patients with adult-onset diabetes. VI. Supplementary report on nonfatal events in patients treated with tolbutamide.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic | 1976 |
[The diabetic disease (M.D.). Clinical picture and complications].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabeti | 1974 |
[Various problems in diabetes: from the symposium of the 18th Congress of the Japanese Association of Medical Sciences].
Topics: Blood Glucose; Congresses as Topic; Diabetes Mellitus; Diabetic Nephropathies; Diet, Diabetic; Femal | 1971 |
Hyperosmolar nonketotic diabetic coma: vascular complications.
Topics: Adult; Aged; Brain Edema; Diabetic Coma; Diabetic Nephropathies; Esophageal and Gastric Varices; Fem | 1974 |
[What is reliable in the therapy of diabetes mellitus?].
Topics: Carbutamide; Chlorpropamide; Chronic Disease; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nep | 1970 |
[Extreme hypoglycemia during combined tolbutamide, n-1-butylbiguanide hydrochloride and chloramphenicol therapy].
Topics: Age Factors; Aged; Biguanides; Chloramphenicol; Diabetes Mellitus; Diabetic Angiopathies; Diabetic N | 1972 |
Aging and diabetes.
Topics: Administration, Oral; Adult; Aged; Aging; Arteriosclerosis; Blood Pressure; Body Weight; Cortisone; | 1971 |
[Classification and clinical picture of diabetes mellitus].
Topics: Age Factors; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropat | 1970 |
Diabetic glomerulosclerosis in the absence of glucose intolerance.
Topics: Adult; Carbohydrate Metabolism; Cortisone; Diabetes Mellitus; Diabetic Nephropathies; Glomerular Fil | 1971 |
[Diabetes mellitus and reduced glucose tolerance in liver cirrhosis].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Glucose Tolerance Test; Humans; I | 1968 |