tolbutamide has been researched along with Diabetes Mellitus, Type 1 in 131 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Isolated rat islets were incubated in the presence of immunoglobulin preparations from patients with insulin-dependent and non-insulin-dependent diabetes mellitus (IDDM, NIDDM) and healthy subjects, and stimulated with D-glucose, L-arginine or tolbutamide." | 3.68 | Islet cell surface antibodies preferentially inhibit glucose-stimulated insulin release in vitro. ( Kajiyama, S; Kanatsuna, T; Kano, Y; Kitagawa, Y; Kondo, M; Ludvigsson, J; Nakamura, N; Nakamura, Y; Nakano, K, 1990) |
| "Tolbutamide was shown to have no independent effect on VLDL TG or VLDL apo B production in four insulin-deficient diabetic subjects." | 1.29 | VLDL production is decreased to a similar extent by acute portal vs. peripheral venous insulin. ( Lewis, GF; Steiner, G; Szeto, L; Uffelman, KD; Weller, B; Zinman, B, 1994) |
| "Basal values of T increased in both T-IDDM and T-NIDDM, compared to IDDM and NIDDM, respectively." | 1.28 | Chronic effects of tolbutamide on myocardial tension during ischemia and reperfusion in perfused hearts isolated from insulin dependent and non insulin dependent diabetic rats. ( Mimura, G; Murakami, K; Oshiro, K; Sunagawa, R, 1991) |
| "SI was normalized in IDDM in clinical remission despite a continued poor insulin secretory response to both glucose and tolbutamide." | 1.28 | A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes. ( Dupre, J; Finegood, DT; Hramiak, IM, 1990) |
| "No increase was noted in patients with Type 2 diabetes or with IGT." | 1.28 | Basal and tolbutamide-induced plasma somatostatin in healthy subjects and in patients with diabetes and impaired glucose tolerance. ( De Vroede, M; Michotte, Y; Segers, O; Somers, G, 1989) |
| "With overt IDDM, insulin levels are low and unresponsive." | 1.27 | Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat. ( Marliss, EB; Nakhooda, AF; Poussier, P, 1983) |
| "tolbutamide was significantly enhanced compared to the C-peptide secretion observed during arginine infusion alone." | 1.27 | The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus. ( Beischer, W; Heinze, E; Teller, W; Thon, A; Vetter, U, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 111 (84.73) | 18.7374 |
| 1990's | 15 (11.45) | 18.2507 |
| 2000's | 5 (3.82) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FABRYKANT, M | 3 |
| BERTO, R | 1 |
| ASHE, BI | 1 |
| DI GEORGE, AM | 1 |
| CHIOWANICH, P | 1 |
| HOSTOMSKA, L | 1 |
| KLASCHKOVA, J | 1 |
| SEJDOVA, E | 1 |
| LESTRADET, H | 1 |
| ROYER, P | 1 |
| BOSCHERINI, B | 1 |
| HAUGEN, HN | 1 |
| MOSS, JM | 1 |
| DELAWTER, DE | 1 |
| GALLAGHER, EJ | 1 |
| KEEN, H | 1 |
| RUVALCABA, RH | 1 |
| SAMOLS, E | 1 |
| KELLEY, VC | 1 |
| KAYE, R | 3 |
| DAVIDSON, MH | 1 |
| Koster, JC | 2 |
| Remedi, MS | 1 |
| Dao, C | 1 |
| Nichols, CG | 2 |
| Masia, R | 1 |
| Tumini, S | 1 |
| Chiarelli, F | 1 |
| Colombo, C | 1 |
| Barbetti, F | 1 |
| Babenko, AP | 1 |
| Ivancho, ES | 1 |
| de Belle, R | 1 |
| Belmonte, MM | 1 |
| Colle, E | 2 |
| Baker, L | 2 |
| Root, AW | 1 |
| Ratzmann, KP | 1 |
| Schulz, B | 1 |
| Heinke, P | 1 |
| Besch, W | 1 |
| Traeger, J | 1 |
| Dubernard, JM | 1 |
| Pozza, G | 3 |
| Secchi, A | 1 |
| Bosi, E | 1 |
| Pontiroli, AE | 2 |
| Gelet, A | 1 |
| Martin, X | 1 |
| Touraine, JL | 1 |
| Marliss, EB | 1 |
| Nakhooda, AF | 1 |
| Poussier, P | 1 |
| Vetter, U | 1 |
| Heinze, E | 1 |
| Thon, A | 1 |
| Beischer, W | 1 |
| Teller, W | 1 |
| Ganda, OP | 2 |
| Srikanta, S | 1 |
| Brink, SJ | 1 |
| Morris, MA | 1 |
| Gleason, RE | 3 |
| Soeldner, JS | 3 |
| Eisenbarth, GS | 1 |
| Tripathy, BB | 1 |
| Samal, KC | 1 |
| Murty, VK | 1 |
| Misra, PK | 1 |
| Parida, RK | 1 |
| Alberetto, M | 1 |
| Bertoletti, A | 1 |
| Baio, G | 1 |
| Mirel, RD | 1 |
| Ginsberg-Fellner, F | 1 |
| Horwitz, DL | 1 |
| Rayfield, EJ | 1 |
| Verlohren, HJ | 2 |
| Lohmann, D | 2 |
| Widness, JA | 1 |
| Cowett, RM | 1 |
| Zeller, WP | 1 |
| Susa, JB | 1 |
| Rubenstein, AH | 1 |
| Schwartz, R | 1 |
| Dreyer, M | 1 |
| Kühnau, J | 1 |
| Rüdiger, HW | 1 |
| Quon, MJ | 1 |
| Cochran, C | 1 |
| Taylor, SI | 1 |
| Eastman, RC | 1 |
| Streckfus, CF | 1 |
| Marcus, S | 1 |
| Welsh, S | 1 |
| Brown, RS | 1 |
| Cherry-Peppers, G | 1 |
| Brown, RH | 1 |
| Lewis, GF | 4 |
| Zinman, B | 3 |
| Uffelman, KD | 1 |
| Szeto, L | 1 |
| Weller, B | 2 |
| Steiner, G | 2 |
| Christiansen, E | 2 |
| Tibell, A | 2 |
| Võlund, A | 1 |
| Rasmussen, K | 2 |
| Tydén, G | 2 |
| Pedersen, O | 1 |
| Christensen, NJ | 1 |
| Madsbad, S | 2 |
| Polonsky, KS | 1 |
| Osei, K | 2 |
| Henry, M | 1 |
| Ferguson, R | 1 |
| Williams, AJ | 1 |
| Beales, PE | 1 |
| Krug, J | 1 |
| Procaccini, E | 1 |
| Signore, A | 1 |
| Xu, S | 1 |
| Gale, EA | 1 |
| Pozzilli, P | 1 |
| Groenewoud, Y | 1 |
| Vranic, M | 2 |
| Giacca, A | 2 |
| Cottrell, DA | 2 |
| Buschard, K | 1 |
| Bock, T | 1 |
| Pedersen, CR | 1 |
| Hansen, SV | 1 |
| Aaen, K | 1 |
| Jørgensen, M | 1 |
| Hansen, MW | 1 |
| Kjaer, TW | 1 |
| Hageman, I | 1 |
| Josefsen, K | 1 |
| AvRuskin, TW | 1 |
| Juan, CS | 1 |
| Adibi, SA | 1 |
| Morse, EL | 1 |
| Amin, PM | 1 |
| Smith, TM | 1 |
| Kilo, C | 1 |
| Williamson, JR | 1 |
| Fajans, SS | 2 |
| Cloutier, MC | 1 |
| Crowther, RL | 1 |
| Shen, SW | 1 |
| Bressler, R | 1 |
| Ellorhaoui, M | 1 |
| Jahnke, KA | 1 |
| Reis, HE | 1 |
| Jahnke, K | 1 |
| Willms, B | 1 |
| Takeda, R | 1 |
| Usukura, N | 1 |
| Miwa, U | 1 |
| Nakabayashi, H | 1 |
| Kishitani, M | 1 |
| Krause, U | 1 |
| Cordes, U | 1 |
| Beyer, J | 1 |
| Sodoyez-Goffaux, F | 1 |
| Sodoyez, JC | 1 |
| Atzenhofer, K | 1 |
| Schnetz, H | 1 |
| Johansen, K | 5 |
| Gottlieb, MS | 1 |
| Park, BN | 1 |
| Kaufmann, RL | 1 |
| Tan, MH | 1 |
| Otto-Buczkowska, E | 1 |
| Kokot, F | 1 |
| Kuska, J | 1 |
| Chiumello, G | 4 |
| Bierman, EL | 1 |
| Henry, ML | 1 |
| Tesi, RJ | 1 |
| Ferguson, RM | 1 |
| O'Dorisio, TM | 1 |
| Oshiro, K | 1 |
| Murakami, K | 1 |
| Sunagawa, R | 1 |
| Mimura, G | 1 |
| Finegood, DT | 1 |
| Hramiak, IM | 1 |
| Dupre, J | 1 |
| Kitagawa, Y | 1 |
| Kanatsuna, T | 1 |
| Kajiyama, S | 1 |
| Nakamura, N | 1 |
| Nakamura, Y | 1 |
| Kano, Y | 1 |
| Nakano, K | 1 |
| Kondo, M | 1 |
| Ludvigsson, J | 1 |
| Segers, O | 1 |
| De Vroede, M | 1 |
| Michotte, Y | 1 |
| Somers, G | 1 |
| Borisova, AM | 3 |
| Koev, D | 2 |
| Kirilov, G | 3 |
| Chiba, T | 1 |
| Okimura, Y | 1 |
| Kodama, H | 1 |
| Kadowaki, S | 1 |
| Chihara, K | 1 |
| Fujita, T | 1 |
| Mokuda, O | 1 |
| Murakami, I | 1 |
| Ikeda, T | 1 |
| Tominaga, M | 1 |
| Mashiba, H | 1 |
| Amemiya, S | 1 |
| Higashida, K | 1 |
| Fujimoto, M | 1 |
| Asayama, K | 1 |
| Ichimura, K | 1 |
| Kusano, S | 1 |
| Ohyama, K | 1 |
| Kato, K | 1 |
| Ovcharova, N | 1 |
| Ser, I | 2 |
| Schemmel, K | 1 |
| Haupt, E | 1 |
| Leybold, K | 1 |
| Lister, J | 1 |
| Lundbaek, K | 1 |
| Lenti, G | 2 |
| Gajdos, A | 1 |
| Pagliara, AS | 1 |
| Karl, IE | 1 |
| Kipnis, DB | 1 |
| Parra, A | 1 |
| Pérez-Pasten, E | 1 |
| Rosales, R | 1 |
| Cervantes, C | 1 |
| Argote, RM | 1 |
| García, G | 1 |
| Adlung, J | 1 |
| Koch, CD | 1 |
| Gottesbüren, H | 1 |
| Schmidt, E | 1 |
| Menge, H | 1 |
| Bloch, R | 1 |
| Lorenz-Meyer, H | 1 |
| Riecken, EO | 1 |
| Del Guercio, MJ | 1 |
| Di Natale, B | 1 |
| Devetta, M | 1 |
| Caccamo, A | 1 |
| Rosenbloom, AL | 3 |
| Bianchi, R | 1 |
| Chin, FT | 1 |
| Guthrie, RA | 2 |
| Guthrie, DW | 1 |
| Baker, HW | 1 |
| Jackson, RL | 2 |
| Cicognani, A | 1 |
| Tassoni, P | 1 |
| Pirazzoli, P | 1 |
| Collina, A | 1 |
| Cacciari, E | 1 |
| Ludwiczak, H | 1 |
| Symonides-Lawecka, A | 1 |
| Rogala, H | 2 |
| Lawecki, J | 2 |
| Fedorowicz, B | 1 |
| Pildes, RS | 2 |
| Drash, A | 3 |
| Ehrlich, RM | 1 |
| Martin, JM | 1 |
| Balsam, MJ | 1 |
| Carroll, KF | 1 |
| Nestel, PJ | 1 |
| Peden, VH | 1 |
| Powell, KR | 1 |
| Rejent, AJ | 1 |
| Grabner, W | 1 |
| Bergner, D | 1 |
| Sommer, B | 1 |
| Ghidoni, A | 1 |
| Lacy, PE | 1 |
| Handwerger, S | 1 |
| Roth, J | 1 |
| Gorden, P | 1 |
| Di Sant' Agnese, P | 1 |
| Carpenter, DF | 1 |
| Peter, G | 1 |
| Jacker, HJ | 1 |
| Kipnis, DM | 3 |
| Hermon-Taylor, J | 1 |
| Parker, ML | 1 |
| Chao, KL | 1 |
| Cornblath, M | 1 |
| Bacon, GE | 1 |
| Parkhurst, RD | 1 |
| Lubetzki, J | 1 |
| Schiff, D | 1 |
| Stern, L | 1 |
| Laor, J | 1 |
| Levitus, Z | 1 |
| Floyd, JC | 1 |
| Pek, S | 1 |
| Conn, JW | 1 |
| Daweke, H | 1 |
| Grote, W | 1 |
| Gries, FA | 1 |
| Liebermeister, H | 1 |
| Rehfeld, JF | 1 |
| Kowalski, H | 1 |
| Kuntz, E | 1 |
| Sperling, M | 1 |
| Schiavini, CA | 1 |
| Quaglia, P | 1 |
| Raptis, S | 1 |
| Rothenbuchner, G | 1 |
| Pfeiffer, EF | 1 |
| Carlström, S | 1 |
| Lundquist, A | 1 |
| Lundquist, I | 1 |
| Nordén, A | 1 |
| Scherstén, B | 1 |
| Wollmark, G | 1 |
| Pagano, G | 2 |
| Mascia, V | 2 |
| Cirillo, R | 2 |
| Pellegrini, A | 2 |
| Falorni, A | 1 |
| Sachsse, B | 1 |
| Yazdanfar, A | 1 |
| Field, JB | 1 |
| Garces, LY | 1 |
| Kenny, FM | 1 |
| Mintz, D | 1 |
| Vazquez, AM | 1 |
| Gellissen, K | 1 |
| Weber, B | 1 |
| Helge, H | 1 |
| Sihombing, G | 1 |
| Orskov, H | 1 |
| Creutzfeldt, W | 1 |
| Frerichs, H | 1 |
| Kosaka, K | 1 |
| Hagura, R | 1 |
| Saito, R | 1 |
| Tsukamoto, F | 1 |
| Kuzuya, T | 1 |
| Murthy, DY | 1 |
| Womack, WN | 1 |
| Muntoni, S | 1 |
| Boero, A | 1 |
| Corona, M | 1 |
| Schneider, H | 1 |
| Colombo, JP | 1 |
| Braunsteiner, H | 1 |
| Hansen, W | 1 |
| Jung, A | 1 |
| Sailer, S | 1 |
8 reviews available for tolbutamide and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Clinical and etiological heterogeneity of idiopathic diabetes mellitus. The banting memorial lecture.
Topics: Adenoma, Islet Cell; Adult; Antibodies, Viral; Autoantibodies; Cell Adhesion; Chlorpropamide; Chromo | 1979 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
[Early diagnosis and prevention of Diabetes mellitus].
Topics: Austria; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; England; Female; Germany, East | 1975 |
Pathobiology of the islets of Langerhans.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Insulin; Insulin Secretion; Islets of Langerh | 1969 |
[Antidiabetics. 42].
Topics: Adolescent; Adult; Aged; Biguanides; Carbutamide; Child; Child, Preschool; Diabetes Mellitus; Diabet | 1969 |
Insulin secretion in normal and diabetic individuals.
Topics: Adolescent; Amino Acids; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose; | 1970 |
[A review of pancreatic transplantation in man, and function of the pancreaticoduodenal graft].
Topics: Adult; Diabetes Mellitus, Type 1; Duodenum; Humans; Insulin; Pancreas; Pancreas Transplantation; Pan | 1970 |
Metabolic considerations in the treatment of juvenile diabetes mellitus.
Topics: Acid-Base Equilibrium; Amino Acids; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Diab | 1969 |
9 trials available for tolbutamide and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Direct comparison of standard and insulin modified protocols for minimal model estimation of insulin sensitivity in normal subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Insulin; In | 1994 |
Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucose | 1994 |
Role of insulin and glucose in the induction of hypoaminoacidemia in man: studies in normal, juvenile diabetic, and insuloma patients.
Topics: Adenoma, Islet Cell; Administration, Oral; Adolescent; Adult; Amino Acids; Blood Glucose; Clinical T | 1975 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
Chemical diabetes mellitus in siblings of children with overt diabetes.
Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hyperins | 1972 |
Tolbutamide in chemical diabetes mellitus in children.
Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; | 1973 |
Criteria for the selection of patients for treatment with tolbutamide.
Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diet Therapy; Evaluation Studies as Topi | 1973 |
Oral substitutes for insulin: modern appraisal of their action and indications.
Topics: Adolescent; Adult; Aged; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, | 1972 |
Studies in subjects with positive postprandial Clinistix test. 3. Special studies and follow-up of cases with borderline glucose tolerance.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Fas | 1971 |
115 other studies available for tolbutamide and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Favorable effects of supplemental orinase in insulin-treated labile diabetes.
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Tolbutamide | 1957 |
Use of orinase as a basic adjuvant in management of insulin-dependent diabetes.
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Tolbutamide | 1958 |
[Clinical study of tolbutamide therapy of juvenile diabetes].
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Tolbutamide | 1958 |
Combined insulin-tolbutamide therapy in the management of insulin-dependent diabetes.
Topics: Diabetes Mellitus, Type 1; Disease Management; Insulin; Tolbutamide | 1959 |
The intravenous tolbut-amide response test in infants and children. A preliminary report.
Topics: Adolescent; Amides; Child; Diabetes Mellitus, Type 1; Humans; Infant; Tolbutamide | 1962 |
[EFFECT OF TOLBUTAMIDE IN DIABETES IN CHILDREN AND ADOLESCENTS].
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Humans; Tolbutamide | 1963 |
[SECONDARY HEPATIC GLYCOGENOSIS].
Topics: Adolescent; Adrenocortical Hyperfunction; Carbohydrate Metabolism; Cataract; Child; Diabetes Mellitu | 1963 |
[DIABETES MELLITUS IN THE WILLI-PRADER SYNDROME].
Topics: Adolescent; Child; Congenital Abnormalities; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dwarfism; | 1963 |
[EXPLORATION OF CARBOHYDRATE METABOLISM IN CHILDREN BY INTRAVENOUS ADMINISTRATION OF TOLBUTAMIDE].
Topics: Administration, Intravenous; Adolescent; Blood Glucose; Carbohydrate Metabolism; Child; Diabetes Mel | 1963 |
THE BLOOD CONCENTRATION OF THIAMINE IN DIABETES.
Topics: Blood; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Drug Therapy; Fasting; Geriatric | 1964 |
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN.
Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete | 1964 |
THE FAMILY DOCTOR AND THE DIABETIC.
Topics: Acidosis; Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic | 1965 |
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Dru | 1965 |
LIMITATIONS IN THE USE OF ORAL HYPOGLYCEMIC AGENTS IN JUVENILE PATIENTS WITH DIABETES.
Topics: Adolescent; Blood Chemical Analysis; Blood Glucose; Body Weight; Child; Cholesterol; Diabetes Mellit | 1965 |
ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy.
Topics: Adenosine Triphosphate; Animals; Cell Line; Diabetes Mellitus, Type 1; Glyburide; Humans; Hypoglycem | 2005 |
An ATP-binding mutation (G334D) in KCNJ11 is associated with a sulfonylurea-insensitive form of developmental delay, epilepsy, and neonatal diabetes.
Topics: Adenosine Triphosphate; Adolescent; Alleles; ATP-Binding Cassette Transporters; Binding Sites; Devel | 2007 |
A novel ABCC8 (SUR1)-dependent mechanism of metabolism-excitation uncoupling.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cell Polarity; Chlorocebus aethi | 2008 |
[Hypoglycemic coma due to oranyl].
Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Humans; Male; Tolbutamide | 1966 |
Effect of intravenous tolbutamide in juvenile diabetes mellitus.
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Fatty Acids, Nonesterif | 1967 |
The early partial remission of juvenile diabetes mellitus. The roles of insulin and growth hormone.
Topics: Blood Glucose; Body Height; Body Weight; Calorimetry; Child; Diabetes Mellitus, Type 1; Fatty Acids, | 1967 |
Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Fatty Acids, Nonesterified; Glucagon; G | 1984 |
Functional study of insulin secretion pattern following segmental neoprene-injected pancreatic allograft in insulin-dependent (type 1) diabetic recipients.
Topics: Adult; Arginine; Cyclosporins; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; I | 1983 |
Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 1983 |
The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus.
Topics: Adolescent; Arginine; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose | 1983 |
Differential sensitivity to beta-cell secretagogues in "early," type I diabetes mellitus.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secr | 1984 |
Insulin response to sulphonylureas in diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; Tolbutamide | 1984 |
Sulfonylureas enhance in vivo the effectiveness of insulin in type 1 (insulin dependent) diabetes mellitus.
Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Female; Glipizide; | 1984 |
C-Peptide reserve in insulin-dependent diabetes. Comparative responses to glucose, glucagon and tolbutamide.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glu | 1980 |
[The significance of insulin secretion in the pathogenesis of diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Secretion; Islets o | 1981 |
Permanent neonatal diabetes in an infant of an insulin-dependent mother.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Humans; Infant, Newborn; Insulin; Male; Receptor, Insulin; Tol | 1982 |
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
Topics: Adolescent; Adult; Blushing; C-Peptide; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, | 1980 |
Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.
Topics: Aged; Analysis of Variance; Baltimore; Black People; Case-Control Studies; Diabetes Mellitus; Diabet | 1994 |
VLDL production is decreased to a similar extent by acute portal vs. peripheral venous insulin.
Topics: Adult; Apolipoproteins B; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Humans; Hyperinsuli | 1994 |
A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; | 1994 |
Differential effects of systemic insulin delivery and prednisone on tissue glucose and insulin sensitivity in insulin-dependent diabetes mellitus pancreas recipients.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1994 |
Tolbutamide reduces the incidence of diabetes mellitus, but not insulitis, in the non-obese-diabetic mouse.
Topics: Aging; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diazoxide; Female; Insulin; Islets of Lang | 1993 |
Defects in quantitative and qualitative beta-cell function following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation (DSSGMEPT).
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Fasting; | 1993 |
Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.
Topics: Adult; Algorithms; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucon | 1996 |
Normalization of insulin sensitivity and glucose homeostasis in type I diabetic pancreas transplant recipients: a 48-month cross-sectional study--a clinical research center study.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Food; G | 1996 |
Glucagon enhances the direct suppressive effect of insulin on hepatic glucose production in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Glucagon; Glucose; Human | 1997 |
Neonatal treatment with beta-cell stimulatory agents reduces the incidence of diabetes in BB rats.
Topics: Animals; Animals, Newborn; Arginine; Diabetes Mellitus, Type 1; Drug Combinations; Female; Glucagon; | 2000 |
Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway?
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 2002 |
Monozygotic triplets with discordance for diabetes mellitus and diabetic microangiopathy.
Topics: Adolescent; Adult; Antigens; Basement Membrane; Blood Glucose; Capillaries; Cortisone; Diabetes Mell | 1977 |
[Various disturbances in beta cell function in diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Islets of | 1977 |
[Assessment of the B-cell function in diabetic patients by means of the determination of insulin secretion following glucose-tolbutamide stimulation].
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Insulin | 1976 |
[The importance of serum insulin determination in the diagnosis and treatment of diabetes mellitus (author's transl)].
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Dose-Response Relationshi | 1975 |
Plasma immunoreactive insulin response to 100g-glucose-glucagon-tolbutamide stimulation in juvenile-onset diabetics.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin | 1977 |
[C-peptide: secretion and metabolism in different functional states and with abnormal B-cell function (author's transl)].
Topics: C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Half-Life; Humans; Insulin; Pancre | 1977 |
Transient diabetes mellitus in a neonate. Evaluation of insulin, glucagon, and growth hormone secretion and management with a continuous low-dose insulin infusion.
Topics: Adolescent; Antigens; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance | 1977 |
Serum insulin and growth hormone response patterns in monozygotic twin siblings of patients with juvenile-onset diabetes.
Topics: Adolescent; Adult; Antigens; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diseases in Twins; Fat | 1975 |
[Benign diabetes in children (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diagnosis, Differential; Female; Hum | 1975 |
[Infantile diabetes].
Topics: Adolescent; Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Hu | 1976 |
The oral antidiabetic agents.
Topics: Administration, Oral; Adult; Blood Glucose; Body Weight; Cardiovascular Diseases; Diabetes Mellitus; | 1976 |
Minimal model analysis of insulin sensitivity and glucose-mediated glucose disposal in type 1 (insulin-dependent) diabetic pancreas allograft recipients.
Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 1; Female; Humans; Insul | 1992 |
Chronic effects of tolbutamide on myocardial tension during ischemia and reperfusion in perfused hearts isolated from insulin dependent and non insulin dependent diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1991 |
A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes.
Topics: Adolescent; Adult; Blood Glucose; Child; Computer Simulation; Diabetes Mellitus, Type 1; Dose-Respon | 1990 |
Islet cell surface antibodies preferentially inhibit glucose-stimulated insulin release in vitro.
Topics: Adolescent; Adult; Animals; Arginine; Autoantibodies; Child; Diabetes Mellitus; Diabetes Mellitus, T | 1990 |
Basal and tolbutamide-induced plasma somatostatin in healthy subjects and in patients with diabetes and impaired glucose tolerance.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucose To | 1989 |
[An improvement in insulin efficacy in patients with type-1 diabetes mellitus following treatment using an insulin infusion pump].
Topics: Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Drug Evaluation; Humans; Insul | 1989 |
[Factors affecting stability in the course of insulin-dependent diabetes mellitus].
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Chronic Disease; Circadian Rhythm; Diabetes Mellitus, T | 1989 |
Tolbutamide inhibits gastrin release in man.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Routes; Female; Gastric Acid; G | 1988 |
Plasma glucose response after intravenous injection of tolbutamide in insulin-treated type I and type II diabetic patients.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; | 1988 |
Residual pancreatic beta-cell function in insulin-dependent diabetes mellitus.
Topics: Adolescent; Arginine; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Glucose Toleranc | 1987 |
[Insulin secretion and action in acromegaly].
Topics: Acromegaly; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Gro | 1987 |
Plasma-insulin in a young diabetic after 13 years' oral therapy.
Topics: Administration, Oral; Adolescent; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans; Insulin; | 1971 |
[In-vitro changes of the serum binding capacity for 131 I-insulin under tolbutamide and glybenclamide in normal persons, in juvenile and senile diabetes, as well as in insulin resistance].
Topics: Age Factors; Blood Glucose; Chromatography, Gel; Cyclohexanes; Diabetes Mellitus; Diabetes Mellitus, | 1970 |
The clinical spectrum of juvenile diabetes.
Topics: Child; Child, Preschool; Classification; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; | 1966 |
Plasma-insulin in mild juvenile diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Immunoassay; Insulin; Insu | 1967 |
[The diabetic disease (M.D.). Clinical picture and complications].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabeti | 1974 |
[Some new data on the biochemistry of insulin].
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Amino Acid Sequence; Amino Acids; Animals; Chemical Phe | 1969 |
Transient neonatal diabetes: delayed maturation of the pancreatic beta cell.
Topics: Adenylyl Cyclases; Blood Glucose; Caffeine; Cyclic AMP; Diabetes Mellitus, Type 1; Female; Glucose T | 1973 |
[Hyperinsulinemia in children with chemical diabetes mellitus].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose Toler | 1974 |
Influence of tolbutamide on serum glucose level, specific activity of glucose and glucose oxidation in severe diabetes.
Topics: Adolescent; Adult; Aged; Blood Glucose; Carbon Dioxide; Carbon Radioisotopes; Diabetes Mellitus; Dia | 1974 |
The effect of diabetes mellitus and insulin on the absorption of glucose, water and electrolytes by the small intestine in man.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Humans; Insulin; Intestinal Absorption; Jejun | 1973 |
B-pancreatic function in obese and diabetic children.
Topics: Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Ethylenediamines; Female; Glucagon; Gluco | 1972 |
[Infantile diabetes and treatment with oral hypoglycemizing agents (function tests of the endocrine pancreatic before and after one year of therapy)].
Topics: Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Glyburide; Human | 1972 |
[Spontaneous remissions in the early stage of diabetes in children].
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Male; Remissio | 1972 |
Adult-onset diabetes mellitus in childhood.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fa | 1973 |
Treatment of the child with chemical diabetes mellitus.
Topics: Child; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypoglycemia; I | 1973 |
Early diabetes mellitus in children.
Topics: Body Weight; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diet Therapy; Female; Follow-Up Stu | 1973 |
Chemical diabetes in children: tolbutamide experience.
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucose Tolerance | 1973 |
Diurnal variation in glucose tolerance and in insulin secretion in man.
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; | 1973 |
Glucose intolerance in a three-year-old child with cystic fibrosis.
Topics: Anti-Bacterial Agents; Blood Glucose; Child, Preschool; Cystic Fibrosis; Diabetes Mellitus, Type 1; | 1974 |
[Accuracy of radioimmunologic insulin determination].
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Iodine Isotopes; Isotope Labeling; Pa | 1974 |
[Behavior of insulin-like activity in juvenile diabetics].
Topics: Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; Islets | 1966 |
Glucose intolerance in cystic fibrosis.
Topics: Adolescent; Adult; Blood Glucose; Child; Cystic Fibrosis; Diabetes Mellitus; Diabetes Mellitus, Type | 1969 |
Juvenile diabetes mellitus, a deficiency in insulin.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insuli | 1968 |
[Considerations on diabetic angiopathies. Relations to hypoglycemic treatments].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dia | 1972 |
Metabolic and growth patterns in transient neonatal diabetes.
Topics: Birth Weight; Blood Glucose; Body Height; Body Weight; Diabetes Mellitus, Type 1; Glucose; Glucose T | 1972 |
[The diagnostic value of insulin measurement in juvenile diabetes and in diabetics on peroral therapy].
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Humans | 1971 |
The course of asymptomatic diabetes in young people, as determined by levels of blood glucose and plasma insulin.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; | 1969 |
[Genetics of diabetes mellitus: glucose tolerance, serum insulin and free fatty acids in monozygotic twins].
Topics: Adult; Blood Glucose; Blood Group Antigens; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dis | 1970 |
Insulin responses of children with chemical diabetes mellitus.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fe | 1970 |
A case of asymptomatic juvenile diabetes mellitus with severe insulin deficiency.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Glycosuria; Hum | 1970 |
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; | 1970 |
[Classification and clinical picture of diabetes mellitus].
Topics: Age Factors; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropat | 1970 |
Evolution of diabetes mellitus from hypoglycemia.
Topics: Adolescent; Blood Glucose; Child; Chronic Disease; Diabetes Mellitus, Type 1; Drug Tolerance; Female | 1971 |
[On a case of diabetes mellitus with unusual evolution].
Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Tes | 1971 |
[Progress in the therapy of diabetes].
Topics: Adrenal Cortex Hormones; Adult; Aged; Aminocaproates; Animals; Biguanides; Blood Glucose; Child; Dia | 1971 |
Mild carbohydrate intolerance developing into classic juvenile diabetes.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Glucose Tol | 1971 |
[The dynamics of free and conugated insulin of the blood in infantile prediabetes and diabetes. Physiopathological considerations].
Topics: Adolescent; Adult; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Human | 1967 |
[Criteria for the diagnosis of early diabetes].
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Child, Preschool; Cortisone; Diabetes Mellitus; Diabe | 1968 |
[The dynamics of insulinemia in man after administration of tolbutamide].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Insulin; Mid | 1968 |
Endogenous insulin and growth hormone response in children with newly diagnosed diabetes mellitus.
Topics: Adolescent; Arginine; Carbon Dioxide; Child; Child, Preschool; Chlorides; Diabetes Mellitus, Type 1; | 1968 |
[The intravenous tolbutamide test in childhood].
Topics: Adolescent; Age Factors; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; | 1968 |
[Mild diabetes mellitus in children and young adults. Clinical features and endogenous insulin response].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucose Toleran | 1968 |
Insulin secretion in diabetes mellitus.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; | 1968 |
[Plasma concentrations of insulin and free fatty acids in juvenile diabetes after loading with tolbutamide and glucagon].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Glucagon | 1968 |
Plasma insulin during remission in juvenile diabetes mellitus.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Female; Glucose Tolerance | 1969 |
[Hypoglycemia factitia. A differential diagnostic significant form of hyperinsulinism].
Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Diagnosis, Differential; Female; Humans; Hyper | 1969 |
Changes in plasma insulin and glucose tolerance in stable diabetes in a young woman.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Tes | 1969 |
Chemical and early overt diabetes mellitus in children. II. Effect of intravenous tolbutamide on "insulin reserve".
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; | 1969 |
[Significance and importance of fibrinolytic activation due to tolbutamide].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Fibrinolysis; Humans; Tolbutamide | 1965 |
[Tolbutamide tests in children].
Topics: Adenoma; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diagnosis, Differential; | 1965 |
[Latent diabetic metabolic state in parents of juvenile diabetics].
Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Child; Child, Preschool; Diabetes Mellitu | 1966 |