tolbutamide has been researched along with Developmental Disabilities in 2 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Developmental Disabilities: Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Babenko, AP | 1 |
| Polak, M | 1 |
| Cavé, H | 1 |
| Busiah, K | 1 |
| Czernichow, P | 1 |
| Scharfmann, R | 1 |
| Bryan, J | 1 |
| Aguilar-Bryan, L | 1 |
| Vaxillaire, M | 1 |
| Froguel, P | 1 |
| Masia, R | 1 |
| Koster, JC | 1 |
| Tumini, S | 1 |
| Chiarelli, F | 1 |
| Colombo, C | 1 |
| Nichols, CG | 1 |
| Barbetti, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long-term Sulfonylurea Response and Glucose Control After Switching From Insulin in Children With Diabetes Due to ABCC8 (SUR1) Mutations[NCT02624830] | Phase 4 | 30 participants (Anticipated) | Interventional | 2019-02-15 | Recruiting | ||
| Human Leucocytic Antigen Typing and Mutation of Adenosine Triphosphate Sensitive Potassium Channel Gene in Diabetic Patients Diagnosed Under the Age of One Year.[NCT03169413] | 100 participants (Anticipated) | Observational | 2018-01-31 | Not yet recruiting | |||
| Long-term Sulfonylurea Response and Glucose Control After Switching From Insulin in Children With Diabetes Due to KCNJ11 (KIR6.2) Mutations[NCT02624817] | Phase 4 | 90 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| Switching From Insulin to Sulfonylurea in Childhood and Adult Diabetes Due to Variants in the HNF1A, HNF4A, or HNF1B Genes[NCT04239586] | Phase 4 | 30 participants (Anticipated) | Interventional | 2017-04-18 | Enrolling by invitation | ||
| Tolerance and Acceptability of Glibentek in Patients With Neonatale Diabetes Secondary to Mutations in K+-ATP Channels[NCT02375828] | Phase 3 | 10 participants (Actual) | Interventional | 2015-03-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for tolbutamide and Developmental Disabilities
| Article | Year |
|---|---|
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Topics: ATP-Binding Cassette Transporters; Birth Weight; Developmental Disabilities; Diabetes Complications; | 2006 |
An ATP-binding mutation (G334D) in KCNJ11 is associated with a sulfonylurea-insensitive form of developmental delay, epilepsy, and neonatal diabetes.
Topics: Adenosine Triphosphate; Adolescent; Alleles; ATP-Binding Cassette Transporters; Binding Sites; Devel | 2007 |